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ANKRD23 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol ANKRD23
Entrez Gene ID 200539
Full Name ankyrin repeat domain 23
Synonyms DARP,MARP3
General protein information
Preferred Names

ankyrin repeat domain 23

Names

ankyrin repeat domain-containing protein 23
diabetes related ankyrin repeat protein
muscle ankyrin repeat protein 3
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

2

2q11.2
Summary This gene is a member of the muscle ankyrin repeat protein (MARP) family and encodes a protein with four tandem ankyrin-like repeats. The protein is localized to the nucleus, functioning as a transcriptional regulator. Expression of this protein is induced during recovery following starvation. [provided by RefSeq, Jul 2008].
Disorder MIM:

610736


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_144994.8 NP_659431.5 ankyrin repeat domain-containing protein 23
NM_144994.7 NP_659431.5 ankyrin repeat domain-containing protein 23

Pathways from BioSystems


Homologies


Rattus norvegicus (Norway rat) Ankrd23 NP_001101681.1
Pan troglodytes (chimpanzee) ANKRD23 XP_001151487.1
Canis lupus familiaris (dog) ANKRD23 XP_538465.2
Homo sapiens (human) ANKRD23 NP_659431.5
Bos taurus (cattle) ANKRD23 XP_005212450.1
Mus musculus (house mouse) Ankrd23 NP_705722.2

Gene Ontology


Bibliography

Related articles in PubMed

Probing muscle ankyrin-repeat protein (MARP) structure and function.
Lun AS, Chen J, Lange S
Anatomical record (Hoboken, N.J. : 2007)297(9)1615-29(2014 Sep)

Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy.
Nagueh SF, Shah G, Wu Y, Torre-Amione G, King NM, Lahmers S, Witt CC, Becker K, Labeit S, Granzier HL
Circulation110(2)155-62(2004 Jul)

The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules.
Miller MK, Bang ML, Witt CC, Labeit D, Trombitas C, Watanabe K, Granzier H, McElhinny AS, Gregorio CC, Labeit S
Journal of molecular biology333(5)951-64(2003 Nov)

Molecular identification and characterization of a novel nuclear protein whose expression is up-regulated in insulin-resistant animals.
Ikeda K, Emoto N, Matsuo M, Yokoyama M
The Journal of biological chemistry278(6)3514-20(2003 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Report structure activity relationships for ANKRD23.
Title: Probing muscle ankyrin-repeat protein (MARP) structure and function.

The following ANKRD23 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ANKRD23 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu06432 NM_144994.8
Latest version!		 Homo sapiens ankyrin repeat domain 23 (ANKRD23), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $154.50-$216.30
$309.00
View Old Accession Versions >>
OHu06432 NM_144994.7 Homo sapiens ankyrin repeat domain 23 (ANKRD23), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $154.50-$216.30
$309.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu06432
Clone ID Related Accession (Same CDS sequence) NM_144994.8 , NM_144994.7
Accession Version NM_144994.8 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 918bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-29
Organism Homo sapiens(human)
Product ankyrin repeat domain-containing protein 23
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BF827606.1, BC107056.2, AK092564.1, AY196212.1 and AC092636.3. On Nov 22, 2018 this sequence version replaced NM_144994.7. ##Evidence-Data-START## Transcript exon combination :: ERR279873.1184.1, BC107056.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000318357.9/ ENSP00000321679.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGACTTCA TCAGCATTCA GCAGTTGGTA AGTGGAGAAA GAGTTGAAGG GAAAGTGTTG 
GGATTTGGAC ATGGAGTTCC TGACCCTGGA GCCTGGCCTA GTGACTGGAG GAGGGGCCCC 
CAAGAGGCTG TGGCCCGGGA GAAGCTGAAA TTGGAAGAAG AGAAGAAGAA GAAACTTGAA 
AGATTTAACA GTACCAGATT TAATCTGGAT AACCTGGCTG ACTTGGAAAA CTTGGTTCAA 
AGACGGAAAA AGCGACTGAG ACACAGAGTC CCCCCCAGGA AACCTGAGCC CCTGGTTAAG 
CCGCAGTCCC AGGCCCAGGT GGAGCCTGTG GGCCTGGAGA TGTTCCTGAA GGCAGCTGCT 
GAGAACCAGG AGTACCTGAT TGACAAGTAC TTGACAGACG GAGGGGACCC CAATGCCCAT 
GACAAGCTCC ACCGCACCGC CTTGCACTGG GCCTGTCTGA AGGGTCACAG CCAGCTGGTG 
AACAAGCTGC TGGTGGCAGG TGCCACAGTG GACGCGCGAG ACTTGCTGGA CAGGACACCT 
GTGTTCTGGG CCTGCCGCGG AGGACATCTG GTCATCCTCA AACAGCTGCT TAACCAGGGA 
GCCCGGGTCA ATGCCCGGGA CAAGATCGGG AGCACCCCCC TGCACGTGGC AGTGCGCACC 
CGGCACCCCG ACTGCCTGGA GCACCTCATC GAGTGTGGCG CCCACCTGAA CGCACAGGAT 
AAGGAAGGGG ACACGGCTCT GCACGAGGCC GTGCGGCACG GCAGCTACAA AGCCATGAAG 
CTACTGCTGC TCTATGGGGC CGAGCTGGGG GTGCGGAACG CGGCCTCCGT GACCCCGGTG 
CAGCTGGCTC GAGACTGGCA GCGCGGCATC CGGGAGGCCC TGCAGGCCCA CGTGGCGCAT 
CCCCGCACCC GGTGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_659431.5
CDS30..947
Translation

Target ORF information:

RefSeq Version NM_144994.8
Organism Homo sapiens(human)
Definition Homo sapiens ankyrin repeat domain 23 (ANKRD23), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_144994.8

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGACTTCA TCAGCATTCA GCAGTTGGTA AGTGGAGAAA GAGTTGAAGG GAAAGTGTTG 
GGATTTGGAC ATGGAGTTCC TGACCCTGGA GCCTGGCCTA GTGACTGGAG GAGGGGCCCC 
CAAGAGGCTG TGGCCCGGGA GAAGCTGAAA TTGGAAGAAG AGAAGAAGAA GAAACTTGAA 
AGATTTAACA GTACCAGATT TAATCTGGAT AACCTGGCTG ACTTGGAAAA CTTGGTTCAA 
AGACGGAAAA AGCGACTGAG ACACAGAGTC CCCCCCAGGA AACCTGAGCC CCTGGTTAAG 
CCGCAGTCCC AGGCCCAGGT GGAGCCTGTG GGCCTGGAGA TGTTCCTGAA GGCAGCTGCT 
GAGAACCAGG AGTACCTGAT TGACAAGTAC TTGACAGACG GAGGGGACCC CAATGCCCAT 
GACAAGCTCC ACCGCACCGC CTTGCACTGG GCCTGTCTGA AGGGTCACAG CCAGCTGGTG 
AACAAGCTGC TGGTGGCAGG TGCCACAGTG GACGCGCGAG ACTTGCTGGA CAGGACACCT 
GTGTTCTGGG CCTGCCGCGG AGGACATCTG GTCATCCTCA AACAGCTGCT TAACCAGGGA 
GCCCGGGTCA ATGCCCGGGA CAAGATCGGG AGCACCCCCC TGCACGTGGC AGTGCGCACC 
CGGCACCCCG ACTGCCTGGA GCACCTCATC GAGTGTGGCG CCCACCTGAA CGCACAGGAT 
AAGGAAGGGG ACACGGCTCT GCACGAGGCC GTGCGGCACG GCAGCTACAA AGCCATGAAG 
CTACTGCTGC TCTATGGGGC CGAGCTGGGG GTGCGGAACG CGGCCTCCGT GACCCCGGTG 
CAGCTGGCTC GAGACTGGCA GCGCGGCATC CGGGAGGCCC TGCAGGCCCA CGTGGCGCAT 
CCCCGCACCC GGTGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu06432
Clone ID Related Accession (Same CDS sequence) NM_144994.8 , NM_144994.7
Accession Version NM_144994.7 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 918bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-01
Organism Homo sapiens(human)
Product ankyrin repeat domain-containing protein 23
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BF827606.1, BC107056.2, AK092564.1 and AY196212.1. On Mar 8, 2006 this sequence version replaced NM_144994.6. ##Evidence-Data-START## Transcript exon combination :: ERR279873.1184.1, BC107056.2 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGACTTCA TCAGCATTCA GCAGTTGGTA AGTGGAGAAA GAGTTGAAGG GAAAGTGTTG 
GGATTTGGAC ATGGAGTTCC TGACCCTGGA GCCTGGCCTA GTGACTGGAG GAGGGGCCCC 
CAAGAGGCTG TGGCCCGGGA GAAGCTGAAA TTGGAAGAAG AGAAGAAGAA GAAACTTGAA 
AGATTTAACA GTACCAGATT TAATCTGGAT AACCTGGCTG ACTTGGAAAA CTTGGTTCAA 
AGACGGAAAA AGCGACTGAG ACACAGAGTC CCCCCCAGGA AACCTGAGCC CCTGGTTAAG 
CCGCAGTCCC AGGCCCAGGT GGAGCCTGTG GGCCTGGAGA TGTTCCTGAA GGCAGCTGCT 
GAGAACCAGG AGTACCTGAT TGACAAGTAC TTGACAGACG GAGGGGACCC CAATGCCCAT 
GACAAGCTCC ACCGCACCGC CTTGCACTGG GCCTGTCTGA AGGGTCACAG CCAGCTGGTG 
AACAAGCTGC TGGTGGCAGG TGCCACAGTG GACGCGCGAG ACTTGCTGGA CAGGACACCT 
GTGTTCTGGG CCTGCCGCGG AGGACATCTG GTCATCCTCA AACAGCTGCT TAACCAGGGA 
GCCCGGGTCA ATGCCCGGGA CAAGATCGGG AGCACCCCCC TGCACGTGGC AGTGCGCACC 
CGGCACCCCG ACTGCCTGGA GCACCTCATC GAGTGTGGCG CCCACCTGAA CGCACAGGAT 
AAGGAAGGGG ACACGGCTCT GCACGAGGCC GTGCGGCACG GCAGCTACAA AGCCATGAAG 
CTACTGCTGC TCTATGGGGC CGAGCTGGGG GTGCGGAACG CGGCCTCCGT GACCCCGGTG 
CAGCTGGCTC GAGACTGGCA GCGCGGCATC CGGGAGGCCC TGCAGGCCCA CGTGGCGCAT 
CCCCGCACCC GGTGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_659431.5
CDS30..947
Translation

Target ORF information:

RefSeq Version NM_144994.7
Organism Homo sapiens(human)
Definition Homo sapiens ankyrin repeat domain 23 (ANKRD23), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_144994.7

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGACTTCA TCAGCATTCA GCAGTTGGTA AGTGGAGAAA GAGTTGAAGG GAAAGTGTTG 
GGATTTGGAC ATGGAGTTCC TGACCCTGGA GCCTGGCCTA GTGACTGGAG GAGGGGCCCC 
CAAGAGGCTG TGGCCCGGGA GAAGCTGAAA TTGGAAGAAG AGAAGAAGAA GAAACTTGAA 
AGATTTAACA GTACCAGATT TAATCTGGAT AACCTGGCTG ACTTGGAAAA CTTGGTTCAA 
AGACGGAAAA AGCGACTGAG ACACAGAGTC CCCCCCAGGA AACCTGAGCC CCTGGTTAAG 
CCGCAGTCCC AGGCCCAGGT GGAGCCTGTG GGCCTGGAGA TGTTCCTGAA GGCAGCTGCT 
GAGAACCAGG AGTACCTGAT TGACAAGTAC TTGACAGACG GAGGGGACCC CAATGCCCAT 
GACAAGCTCC ACCGCACCGC CTTGCACTGG GCCTGTCTGA AGGGTCACAG CCAGCTGGTG 
AACAAGCTGC TGGTGGCAGG TGCCACAGTG GACGCGCGAG ACTTGCTGGA CAGGACACCT 
GTGTTCTGGG CCTGCCGCGG AGGACATCTG GTCATCCTCA AACAGCTGCT TAACCAGGGA 
GCCCGGGTCA ATGCCCGGGA CAAGATCGGG AGCACCCCCC TGCACGTGGC AGTGCGCACC 
CGGCACCCCG ACTGCCTGGA GCACCTCATC GAGTGTGGCG CCCACCTGAA CGCACAGGAT 
AAGGAAGGGG ACACGGCTCT GCACGAGGCC GTGCGGCACG GCAGCTACAA AGCCATGAAG 
CTACTGCTGC TCTATGGGGC CGAGCTGGGG GTGCGGAACG CGGCCTCCGT GACCCCGGTG 
CAGCTGGCTC GAGACTGGCA GCGCGGCATC CGGGAGGCCC TGCAGGCCCA CGTGGCGCAT 
CCCCGCACCC GGTGCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Probing muscle ankyrin-repeat protein (MARP) structure and function.
Anatomical record (Hoboken, N.J. : 2007)297(9)1615-29(2014 Sep)
Lun AS,Chen J,Lange S


book

Altered titin expression, myocardial stiffness, and left ventricular function in patients with dilated cardiomyopathy.
Circulation110(2)155-62(2004 Jul)
Nagueh SF,Shah G,Wu Y,Torre-Amione G,King NM,Lahmers S,Witt CC,Becker K,Labeit S,Granzier HL


book

The muscle ankyrin repeat proteins: CARP, ankrd2/Arpp and DARP as a family of titin filament-based stress response molecules.
Journal of molecular biology333(5)951-64(2003 Nov)
Miller MK,Bang ML,Witt CC,Labeit D,Trombitas C,Watanabe K,Granzier H,McElhinny AS,Gregorio CC,Labeit S


book

Molecular identification and characterization of a novel nuclear protein whose expression is up-regulated in insulin-resistant animals.
The Journal of biological chemistry278(6)3514-20(2003 Feb)
Ikeda K,Emoto N,Matsuo M,Yokoyama M