| Gene Symbol | SWAP70 |
| Entrez Gene ID | 23075 |
| Full Name | switching B cell complex subunit SWAP70 |
| Synonyms | HSPC321,SWAP-70 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Disorder MIM: |
The following SWAP70 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SWAP70 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
Online Only Promotion
Up to 50% OFF! Starting
from $49/clone
| CloneID | OHu30276 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_015055.3 , NM_015055.4 | |
| Accession Version | NM_015055.3 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1758bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-12-12 | |
| Organism | Homo sapiens(human) | |
| Product | switch-associated protein 70 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK096859.1, BC000616.2, AC026250.16 and AI693686.1. On Jul 10, 2014 this sequence version replaced NM_015055.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB014540.1, SRR1803615.208775.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGGGAGCT TGAAGGAGGA GCTGCTCAAA GCCATCTGGC ACGCCTTCAC CGCACTCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_055870.2 |
| CDS | 104..1861 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_015055.3 |
1 | ATGGGGAGCT TGAAGGAGGA GCTGCTCAAA GCCATCTGGC ACGCCTTCAC CGCACTCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu30276 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_015055.3 , NM_015055.4 | |
| Accession Version | NM_015055.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1758bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-23 | |
| Organism | Homo sapiens(human) | |
| Product | switch-associated protein 70 isoform 1 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK096859.1, BC000616.2, AC026250.16 and AI693686.1. On Nov 22, 2018 this sequence version replaced NM_015055.3. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AB014540.1, SRR1803615.208775.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000318950.11/ ENSP00000315630.6 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. | |
1 | ATGGGGAGCT TGAAGGAGGA GCTGCTCAAA GCCATCTGGC ACGCCTTCAC CGCACTCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_055870.2 |
| CDS | 104..1861 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_015055.4 |
1 | ATGGGGAGCT TGAAGGAGGA GCTGCTCAAA GCCATCTGGC ACGCCTTCAC CGCACTCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu44798 | |
| Clone ID Related Accession (Same CDS sequence) | XM_005252830.4 | |
| Accession Version | XM_005252830.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1311bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-05 | |
| Organism | Homo sapiens(human) | |
| Product | switch-associated protein 70 isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005252830.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGGAGGAG GTTGGCAGCA AGAACAATTT GAACATTATA AAATCAACTT TGATGACAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_005252887.1 |
| CDS | 452..1762 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_005252830.4 |
1 | ATGGGAGGAG GTTGGCAGCA AGAACAATTT GAACATTATA AAATCAACTT TGATGACAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu44797 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001297714.2 , NM_001297714.1 | |
| Accession Version | NM_001297714.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-25 | |
| Organism | Homo sapiens(human) | |
| Product | switch-associated protein 70 isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK096859.1, BC000616.2, AC026250.16 and AI693686.1. On May 31, 2019 this sequence version replaced NM_001297714.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.65537.1, SRR1660803.192803.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGGGAGCT TGAAGGAGGA GCTGCTCAAA GCCATCTGGC ACGCCTTCAC CGCACTCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001284643.1 |
| CDS | 104..1687 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001297714.2 |
1 | ATGGGGAGCT TGAAGGAGGA GCTGCTCAAA GCCATCTGGC ACGCCTTCAC CGCACTCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu44797 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001297714.2 , NM_001297714.1 | |
| Accession Version | NM_001297714.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1584bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2018-06-29 | |
| Organism | Homo sapiens(human) | |
| Product | switch-associated protein 70 isoform 2 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK096859.1, BC000616.2, AC026250.16 and AI693686.1. On Jul 10, 2014 this sequence version replaced XM_005252829.2. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803614.65537.1, SRR1660809.169621.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGGGAGCT TGAAGGAGGA GCTGCTCAAA GCCATCTGGC ACGCCTTCAC CGCACTCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001284643.1 |
| CDS | 104..1687 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001297714.1 |
1 | ATGGGGAGCT TGAAGGAGGA GCTGCTCAAA GCCATCTGGC ACGCCTTCAC CGCACTCGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
SWAP70 Organizes the Actin Cytoskeleton and Is Essential for Phagocytosis. |
Expression of switch-associated protein 70 is associated with lymphocyte activation and reduced disability in multiple sclerosis. |
The guanine exchange factor SWAP70 mediates vGPCR-induced endothelial plasticity. |
E-cadherin interactome complexity and robustness resolved by quantitative proteomics. |
