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SDF2L1 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol SDF2L1
Entrez Gene ID 23753
Full Name stromal cell derived factor 2 like 1
General protein information
Preferred Names

stromal cell derived factor 2 like 1

Names

stromal cell-derived factor 2-like protein 1
PWP1-interacting protein 8
SDF2-like 1
SDF2-like protein 1
dihydropyrimidinase-like 2

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

22

22q11.21

Disorder MIM:

607551


mRNA and Protein(s)

mRNA Protein Name
NM_022044.2 NP_071327.2 stromal cell-derived factor 2-like protein 1 precursor



Homo sapiens (human) SDF2L1 NP_071327.2
Pan troglodytes (chimpanzee) SDF2L1 XP_001159592.2
Mus musculus (house mouse) Sdf2l1 NP_071719.1
Xenopus tropicalis (tropical clawed frog) LOC101732749 XP_004920914.1
Xenopus tropicalis (tropical clawed frog) sdf2l1 NP_001008033.1
Rattus norvegicus (Norway rat) Sdf2l1 NP_001102903.1
Macaca mulatta (rhesus monkey) SDF2L1 NP_001138539.1
Canis lupus familiaris (dog) SDF2L1 XP_850810.2
Bos taurus (cattle) SDF2L1 NP_001030400.1
Gallus gallus (chicken) SDF2L1 XP_001232858.1
Danio rerio (zebrafish) sdf2l1 NP_001003730.2


Related articles in PubMed

SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells.
Tiwari A, Schuiki I, Zhang L, Allister EM, Wheeler MB, Volchuk A
Journal of cell science126(Pt 9)1962-8(2013 May)

A genome annotation-driven approach to cloning the human ORFeome.
Collins JE, Wright CL, Edwards CA, Davis MP, Grinham JA, Cole CG, Goward ME, Aguado B, Mallya M, Mokrab Y, Huckle EJ, Beare DM, Dunham I
Genome biology5(10)R84(2004)

Murine and human SDF2L1 is an endoplasmic reticulum stress-inducible gene and encodes a new member of the Pmt/rt protein family.
Fukuda S, Sumii M, Masuda Y, Takahashi M, Koike N, Teishima J, Yasumoto H, Itamoto T, Asahara T, Dohi K, Kamiya K
Biochemical and biophysical research communications280(1)407-14(2001 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

SDF2L1 increases the time that misfolded proteins have to achieve a correctly folded conformation and thus that SDF2L1 can act as a buffer for substrate availability for ERAD in pancreatic beta-cells.
Title: SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells.

The following SDF2L1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SDF2L1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu29585 NM_022044.2
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Homo sapiens stromal cell derived factor 2 like 1 (SDF2L1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$49.50-$69.30
$99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu29585
Clone ID Related Accession (Same CDS sequence) NM_022044.2
Accession Version NM_022044.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 666bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2017-04-26
Organism Homo sapiens(Human)
Product stromal cell-derived factor 2-like protein 1 precursor
Comment VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BM560445.1 and AY359118.1. On Dec 3, 2004 this sequence version replaced NM_022044.1. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.485658.1, SRR1163655.242110.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
ATGTGGAGCG CGGGCCGCGG CGGGGCTGCC TGGCCGGTGC TGTTGGGGCT GCTGCTGGCG 
CTGTTAGTGC CGGGCGGTGG TGCCGCCAAG ACCGGTGCGG AGCTCGTGAC CTGCGGGTCG
GTGCTGAAGC TGCTCAATAC GCACCACCGC GTGCGGCTGC ACTCGCACGA CATCAAATAC
GGATCCGGCA GCGGCCAGCA ATCGGTGACC GGCGTAGAGG CGTCGGACGA CGCCAATAGC
TACTGGCGGA TCCGCGGCGG CTCGGAGGGC GGGTGCCCGC GCGGGTCCCC GGTGCGCTGC
GGGCAGGCGG TGAGGCTCAC GCATGTGCTT ACGGGCAAGA ACCTGCACAC GCACCACTTC
CCGTCGCCGC TGTCCAACAA CCAGGAGGTG AGTGCCTTTG GGGAAGACGG CGAGGGCGAC
GACCTGGACC TATGGACAGT GCGCTGCTCT GGACAGCACT GGGAGCGTGA GGCTGCTGTG
CGCTTCCAGC ATGTGGGCAC CTCTGTGTTC CTGTCAGTCA CGGGTGAGCA GTATGGAAGC
CCCATCCGTG GGCAGCATGA GGTCCACGGC ATGCCCAGTG CCAACACGCA CAATACGTGG
AAGGCCATGG AAGGCATCTT CATCAAGCCT AGTGTGGAGC CCTCTGCAGG TCACGATGAA
CTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_071327.2
CDS85..750
Misc Feature(1)184..336
Misc Feature(2)367..534
Misc Feature(3)562..687
Misc Feature(4)727..729
Misc Feature(5)736..747
Exon (1)1..271
Exon (2)272..468
Exon (3)469..874
Translation

Target ORF information:

RefSeq Version NM_022044.2
Organism Homo sapiens(Human)
Definition Homo sapiens stromal cell derived factor 2 like 1 (SDF2L1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_022044.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
ATGTGGAGCG CGGGCCGCGG CGGGGCTGCC TGGCCGGTGC TGTTGGGGCT GCTGCTGGCG 
CTGTTAGTGC CGGGCGGTGG TGCCGCCAAG ACCGGTGCGG AGCTCGTGAC CTGCGGGTCG
GTGCTGAAGC TGCTCAATAC GCACCACCGC GTGCGGCTGC ACTCGCACGA CATCAAATAC
GGATCCGGCA GCGGCCAGCA ATCGGTGACC GGCGTAGAGG CGTCGGACGA CGCCAATAGC
TACTGGCGGA TCCGCGGCGG CTCGGAGGGC GGGTGCCCGC GCGGGTCCCC GGTGCGCTGC
GGGCAGGCGG TGAGGCTCAC GCATGTGCTT ACGGGCAAGA ACCTGCACAC GCACCACTTC
CCGTCGCCGC TGTCCAACAA CCAGGAGGTG AGTGCCTTTG GGGAAGACGG CGAGGGCGAC
GACCTGGACC TATGGACAGT GCGCTGCTCT GGACAGCACT GGGAGCGTGA GGCTGCTGTG
CGCTTCCAGC ATGTGGGCAC CTCTGTGTTC CTGTCAGTCA CGGGTGAGCA GTATGGAAGC
CCCATCCGTG GGCAGCATGA GGTCCACGGC ATGCCCAGTG CCAACACGCA CAATACGTGG
AAGGCCATGG AAGGCATCTT CATCAAGCCT AGTGTGGAGC CCTCTGCAGG TCACGATGAA
CTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

SDF2L1 interacts with the ER-associated degradation machinery and retards the degradation of mutant proinsulin in pancreatic β-cells.
Journal of cell science126(Pt 9)1962-8(2013 May)
Tiwari A,Schuiki I,Zhang L,Allister EM,Wheeler MB,Volchuk A


book

A genome annotation-driven approach to cloning the human ORFeome.
Genome biology5(10)R84(2004)
Collins JE,Wright CL,Edwards CA,Davis MP,Grinham JA,Cole CG,Goward ME,Aguado B,Mallya M,Mokrab Y,Huckle EJ,Beare DM,Dunham I


book

Murine and human SDF2L1 is an endoplasmic reticulum stress-inducible gene and encodes a new member of the Pmt/rt protein family.
Biochemical and biophysical research communications280(1)407-14(2001 Jan)
Fukuda S,Sumii M,Masuda Y,Takahashi M,Koike N,Teishima J,Yasumoto H,Itamoto T,Asahara T,Dohi K,Kamiya K


 
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