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HEYL cDNA ORF clone, Homo sapiens (human)

Gene Symbol HEYL
Entrez Gene ID 26508
Full Name hes-related family bHLH transcription factor with YRPW motif-like
Synonyms HESR3, HEY3, HRT3, bHLHb33
General protein information
Preferred Names
hairy/enhancer-of-split related with YRPW motif-like protein
Names
hairy/enhancer-of-split related with YRPW motif-like protein
HRT-3
hHRT3
hHeyL
HEY-like protein
hairy-related transcription factor 3
class B basic helix-loop-helix protein 33
hairy/enhancer-of-split related with YRPW motif 3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

1

1p34.3

Summary This gene encodes a member of the hairy and enhancer of split-related (HESR) family of basic helix-loop-helix (bHLH)-type transcription factors. The sequence of the encoded protein contains a conserved bHLH and orange domain, but its YRPW motif has diverged from other HESR family members. It is thought to be an effector of Notch signaling and a regulator of cell fate decisions. Alternatively spliced transcript variants have been found, but their biological validity has not been determined. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

609034


mRNA and Protein(s)

mRNA Protein Name
XM_005270745 XP_005270802 hairy/enhancer-of-split related with YRPW motif-like protein isoform X1
NM_014571 NP_055386 hairy/enhancer-of-split related with YRPW motif-like protein



Homo sapiens (human) HEYL NP_055386.1
Pan troglodytes (chimpanzee) HEYL XP_001171234.1
Macaca mulatta (Rhesus monkey) LOC716117 XP_001113370.1
Canis lupus familiaris (dog) HEYL XP_849702.1
Bos taurus (cattle) HEYL NP_001019736.2
Mus musculus (house mouse) Heyl NP_038933.2
Rattus norvegicus (Norway rat) Heyl NP_001101447.1
Gallus gallus (chicken) HEYL XP_001234406.2
Danio rerio (zebrafish) heyl NP_859425.1


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following HEYL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HEYL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu33344 XM_005270745 PREDICTED: Homo sapiens hes-related family bHLH transcription factor with YRPW motif-like (HEYL), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $139.30
$199.00
OHu06538
NM_014571 Homo sapiens hes-related family bHLH transcription factor with YRPW motif-like (HEYL), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK
$154.50-$216.30
$309.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
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30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu33344
Clone ID Related Accession (Same CDS sequence) XM_005270745
Accession Version XM_005270745.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 903bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product hairy/enhancer-of-split related with YRPW motif-like protein isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_032977.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:530362370. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCAGGC CGCTGTCCAC CCCCAGCTCT TCGCAGATGC AAGCCAGGAA GAAACACAGA 
GGGATCATAG AGAAACGGCG TCGAGACCGC ATCAACAGTA GCCTTTCTGA ATTGCGACGC
TTGGTCCCCA CTGCCTTTGA GAAACAGGGC TCTTCCAAGC TGGAGAAAGC CGAGGTCTTG
CAGATGACGG TGGATCACTT GAAAATGCTC CATGCCACTG GTGGGACAGG ATTCTTTGAT
GCCCGAGCCC TGGCAGTTGA CTTCCGGAGC ATTGGTTTTC GGGAGTGCCT CACTGAGGTC
ATCAGGTACC TGGGGGTCCT TGAAGGGCCC AGCAGCCGTG CAGACCCCGT CCGGATTCGC
CTTCTCTCCC ACCTCAACAG CTACGCAGCC GAGATGGAGC CTTCGCCCAC GCCCACTGGC
CCTTTGGCCT TCCCTGCCTG GCCCTGGTCT TTCTTCCATA GCTGTCCAGG GCTGCCAGCC
CTGAGCAACC AGCTCGCCAT CCTGGGAAGA GTGCCCAGCC CTGTCCTCCC CGGTGTCTCC
TCTCCTGCTT ACCCCATCCC AGCCCTCCGA ACCGCTCCCC TTCGCAGAGC CACAGGCATC
ATCCTGCCAG CCCGGAGGAA TGTGCTGCCC AGTCGAGGGG CATCTTCCAC CCGGAGGGCC
CGCCCCCTAG AGAGGCCAGC GACCCCTGTG CCTGTCGCCC CCAGCAGCAG GGCTGCCAGG
AGCAGCCACA TCGCTCCCCT CCTGCAGTCT TCCTCCCCAA CACCCCCTGG TCCTACAGGG
TCGGCTGCTT ACGTGGCTGT TCCCACCCCC AACTCATCCT CCCCAGGGCC AGCTGGGAGG
CCAGCGGGAG CCATGCTCTA CCACTCCTGG GTCTCTGAAA TCACTGAAAT CGGGGCTTTC
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005270802.1
CDS190..1092
Misc Feature(1)229..405(+)
Misc Feature(2)232..357(+)
Misc Feature(3)259..261(+)
Misc Feature(4)277..402(+)
Misc Feature(5)448..591(+)
Translation

Target ORF information:

RefSeq Version XM_005270745
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens hes-related family bHLH transcription factor with YRPW motif-like (HEYL), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_005270745

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGCCAGGC CGCTGTCCAC CCCCAGCTCT TCGCAGATGC AAGCCAGGAA GAAACACAGA 
GGGATCATAG AGAAACGGCG TCGAGACCGC ATCAACAGTA GCCTTTCTGA ATTGCGACGC
TTGGTCCCCA CTGCCTTTGA GAAACAGGGC TCTTCCAAGC TGGAGAAAGC CGAGGTCTTG
CAGATGACGG TGGATCACTT GAAAATGCTC CATGCCACTG GTGGGACAGG ATTCTTTGAT
GCCCGAGCCC TGGCAGTTGA CTTCCGGAGC ATTGGTTTTC GGGAGTGCCT CACTGAGGTC
ATCAGGTACC TGGGGGTCCT TGAAGGGCCC AGCAGCCGTG CAGACCCCGT CCGGATTCGC
CTTCTCTCCC ACCTCAACAG CTACGCAGCC GAGATGGAGC CTTCGCCCAC GCCCACTGGC
CCTTTGGCCT TCCCTGCCTG GCCCTGGTCT TTCTTCCATA GCTGTCCAGG GCTGCCAGCC
CTGAGCAACC AGCTCGCCAT CCTGGGAAGA GTGCCCAGCC CTGTCCTCCC CGGTGTCTCC
TCTCCTGCTT ACCCCATCCC AGCCCTCCGA ACCGCTCCCC TTCGCAGAGC CACAGGCATC
ATCCTGCCAG CCCGGAGGAA TGTGCTGCCC AGTCGAGGGG CATCTTCCAC CCGGAGGGCC
CGCCCCCTAG AGAGGCCAGC GACCCCTGTG CCTGTCGCCC CCAGCAGCAG GGCTGCCAGG
AGCAGCCACA TCGCTCCCCT CCTGCAGTCT TCCTCCCCAA CACCCCCTGG TCCTACAGGG
TCGGCTGCTT ACGTGGCTGT TCCCACCCCC AACTCATCCT CCCCAGGGCC AGCTGGGAGG
CCAGCGGGAG CCATGCTCTA CCACTCCTGG GTCTCTGAAA TCACTGAAAT CGGGGCTTTC
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu06538
Clone ID Related Accession (Same CDS sequence) NM_014571
Accession Version NM_014571.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 987bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags COA
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product hairy/enhancer-of-split related with YRPW motif-like protein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL541019.3, BC006087.1, AL035404.20 and BM682076.1. On Jun 1, 2006 this sequence version replaced gi:19923414. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AL541019.3, BC006087.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA2162946 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAAGCGAC CCAAGGAGCC GAGCGGCTCC GACGGGGAGT CCGACGGACC CATCGACGTG 
GGCCAAGAGG GCCAGCTGAG CCAGATGGCC AGGCCGCTGT CCACCCCCAG CTCTTCGCAG
ATGCAAGCCA GGAAGAAACG CAGAGGGATC ATAGAGAAAC GGCGTCGAGA CCGCATCAAC
AGTAGCCTTT CTGAATTGCG ACGCTTGGTC CCCACTGCCT TTGAGAAACA GGGCTCTTCC
AAGCTGGAGA AAGCCGAGGT CTTGCAGATG ACGGTGGATC ACTTGAAAAT GCTCCATGCC
ACTGGTGGGA CAGGATTCTT TGATGCCCGA GCCCTGGCAG TTGACTTCCG GAGCATTGGT
TTTCGGGAGT GCCTCACTGA GGTCATCAGG TACCTGGGGG TCCTTGAAGG GCCCAGCAGC
CGTGCAGACC CCGTCCGGAT TCGCCTTCTC TCCCACCTCA ACAGCTACGC AGCCGAGATG
GAGCCTTCGC CCACGCCCAC TGGCCCTTTG GCCTTCCCTG CCTGGCCCTG GTCTTTCTTC
CATAGCTGTC CAGGGCTGCC AGCCCTGAGC AACCAGCTCG CCATCCTGGG AAGAGTGCCC
AGCCCTGTCC TCCCCGGTGT CTCCTCTCCT GCTTACCCCA TCCCAGCCCT CCGAACCGCT
CCCCTTCGCA GAGCCACAGG CATCATCCTG CCAGCCCGGA GGAATGTGCT GCCCAGTCGA
GGGGCATCTT CCACCCGGAG GGCCCGCCCC CTAGAGAGGC CAGCGACCCC TGTGCCTGTC
GCCCCCAGCA GCAGGGCTGC CAGGAGCAGC CACATCGCTC CCCTCCTGCA GTCTTCCTCC
CCAACACCCC CTGGTCCTAC AGGGTCGGCT GCTTACGTGG CTGTTCCCAC CCCCAACTCA
TCCTCCCCAG GGCCAGCTGG GAGGCCAGCG GGAGCCATGC TCTACCACTC CTGGGTCTCT
GAAATCACTG AAATCGGGGC TTTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_055386.1
CDS52..1038
Misc Feature(1)175..384(+)
Misc Feature(2)181..351(+)
Misc Feature(3)181..303(+)
Misc Feature(4)205..207(+)
Misc Feature(5)223..348(+)
Misc Feature(6)394..537(+)
Exon (1)1..131
Gene:HEYL
Gene Synonym:
Exon (2)132..198
Gene:HEYL
Gene Synonym:
Exon (3)199..282
Gene:HEYL
Gene Synonym:
Exon (4)283..364
Gene:HEYL
Gene Synonym:
Exon (5)365..4114
Gene:HEYL
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_014571
Organism Homo sapiens (human)
Definition Homo sapiens hes-related family bHLH transcription factor with YRPW motif-like (HEYL), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_014571

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAAGCGAC CCAAGGAGCC GAGCGGCTCC GACGGGGAGT CCGACGGACC CATCGACGTG 
GGCCAAGAGG GCCAGCTGAG CCAGATGGCC AGGCCGCTGT CCACCCCCAG CTCTTCGCAG
ATGCAAGCCA GGAAGAAACG CAGAGGGATC ATAGAGAAAC GGCGTCGAGA CCGCATCAAC
AGTAGCCTTT CTGAATTGCG ACGCTTGGTC CCCACTGCCT TTGAGAAACA GGGCTCTTCC
AAGCTGGAGA AAGCCGAGGT CTTGCAGATG ACGGTGGATC ACTTGAAAAT GCTCCATGCC
ACTGGTGGGA CAGGATTCTT TGATGCCCGA GCCCTGGCAG TTGACTTCCG GAGCATTGGT
TTTCGGGAGT GCCTCACTGA GGTCATCAGG TACCTGGGGG TCCTTGAAGG GCCCAGCAGC
CGTGCAGACC CCGTCCGGAT TCGCCTTCTC TCCCACCTCA ACAGCTACGC AGCCGAGATG
GAGCCTTCGC CCACGCCCAC TGGCCCTTTG GCCTTCCCTG CCTGGCCCTG GTCTTTCTTC
CATAGCTGTC CAGGGCTGCC AGCCCTGAGC AACCAGCTCG CCATCCTGGG AAGAGTGCCC
AGCCCTGTCC TCCCCGGTGT CTCCTCTCCT GCTTACCCCA TCCCAGCCCT CCGAACCGCT
CCCCTTCGCA GAGCCACAGG CATCATCCTG CCAGCCCGGA GGAATGTGCT GCCCAGTCGA
GGGGCATCTT CCACCCGGAG GGCCCGCCCC CTAGAGAGGC CAGCGACCCC TGTGCCTGTC
GCCCCCAGCA GCAGGGCTGC CAGGAGCAGC CACATCGCTC CCCTCCTGCA GTCTTCCTCC
CCAACACCCC CTGGTCCTAC AGGGTCGGCT GCTTACGTGG CTGTTCCCAC CCCCAACTCA
TCCTCCCCAG GGCCAGCTGG GAGGCCAGCG GGAGCCATGC TCTACCACTC CTGGGTCTCT
GAAATCACTG AAATCGGGGC TTTCTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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