HILPDA cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Gene Symbol	HILPDA
Entrez Gene ID	29923
Full Name	hypoxia inducible lipid droplet associated
Synonyms	C7orf68,HIG-2,HIG2
General protein information	Preferred Names hypoxia inducible lipid droplet associated Names hypoxia-inducible lipid droplet-associated protein hypoxia inducible gene 2 hypoxia-inducible gene 2 protein hypoxia-inducible protein 2
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 7 Map Location: 7q32.1

mRNA and Protein(s)

mRNA	Protein	Name
NM_001098786.1	NP_001092256.1	hypoxia-inducible lipid droplet-associated protein
NM_013332.3	NP_037464.1	hypoxia-inducible lipid droplet-associated protein
NM_013332.4	NP_037464.1	hypoxia-inducible lipid droplet-associated protein

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	HILPDA	XP_003951175.1
	HILPDA	XP_001089583.2
Homo sapiens (human)	HILPDA	NP_001092256.1
Rattus norvegicus (Norway rat)	Hilpda	XP_006236300.1
Mus musculus (house mouse)	Hilpda	NP_076005.1

Gene Ontology
Bibliography

Related articles in PubMed

Hypoxia Inducible Lipid Droplet Associated protein inhibits Adipose Triglyceride Lipase.
Padmanabha Das KM, Wechselberger L, Liziczai M, De la Rosa Rodriguez M, Grabner GF, Heier C, Viertlmayr R, Radler C, Lichtenegger J, Zimmermann R, Borst JW, Zechner R, Kersten S, Oberer M
Journal of lipid research(2018 Jan)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Study showed for the first time that HIG-2 and SOX11 mutually co-regulate each other, and that HIG-2 and SOX11 knock-down promote increased proliferation in a non-synergistic manner in primary mantle cell lymphoma cells.
Title: SOX11 and HIG-2 are cross-regulated and affect growth in mantle cell lymphoma.

data uncover HILPDA as a novel PPAR target that raises hepatic triglyceride storage via regulation of triglyceride secretion.
Title: Hypoxia-inducible lipid droplet-associated (HILPDA) is a novel peroxisome proliferator-activated receptor (PPAR) target involved in hepatic triglyceride secretion.

Data indicate that HIG2 (hypoxia-inducible gene 2) is a HIF-1alpha target in regulating cell survival during hypoxia.
Title: HIG2 promotes colorectal cancer progression via hypoxia-dependent and independent pathways.

there was no significant relationship between HIG2 expression and age, clinical stage and histology in either cervical cancer or endometrial cancer.
Title: Expression of hypoxia-inducible 2 (HIG2) protein in uterine cancer.

Data show that DBN1, SETMAR and HIG2 are direct transcriptional targets of the SOX11 protein.
Title: Gene expression profiling and chromatin immunoprecipitation identify DBN1, SETMAR and HIG2 as direct targets of SOX11 in mantle cell lymphoma.

The following HILPDA gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the HILPDA cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08913	NM_001098786.1 Latest version!	Homo sapiens hypoxia inducible lipid droplet associated (HILPDA), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
OHu08913	NM_013332.4 Latest version!	Homo sapiens hypoxia inducible lipid droplet associated (HILPDA), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
View Old Accession Versions >>
OHu08913	NM_013332.3	Homo sapiens hypoxia inducible lipid droplet associated (HILPDA), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$49.50-$69.30 $99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

HILPDA ( NM_001098786.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001092256.1 Homo sapiens hypoxia inducible lipid droplet associated (HILPDA), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OHu08913
Clone ID Related Accession (Same CDS sequence)	NM_001098786.1 , NM_013332.3 , NM_013332.4
Accession Version	NM_001098786.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 192bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Homo sapiens(human)
Product	hypoxia-inducible lipid droplet-associated protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CD686848.1, AL691669.1, CX784347.1, AF144755.1 and BC008573.1. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 both encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163657.118253.1, SRR1803617.222185.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCATG TGTTGAACCT CTACCTGTTA GGTGTGGTAC TGACCCTACT CTCCATCTTC 
GTTAGAGTGA TGGAGTCCCT AGAGGGCTTA CTAGAGAGCC CATCGCCTGG GACCTCCTGG 
ACCACCAGAA GCCAACTAGC CAACACAGAG CCCACCAAGG GCCTTCCAGA CCATCCATCC 
AGAAGCATGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001092256.1
CDS	149..340
Translation	MKHVLNLYLLGVVLTLLSIFVRVMESLEGLLESPSPGTSWTTRSQLANTEPTKGLPDHPSRSM

Target ORF information:

RefSeq Version	NM_001098786.1
Organism	Homo sapiens(human)
Definition	Homo sapiens hypoxia inducible lipid droplet associated (HILPDA), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001098786.1

ORF Insert Sequence:

ATGAAGCATG TGTTGAACCT CTACCTGTTA GGTGTGGTAC TGACCCTACT CTCCATCTTC 
GTTAGAGTGA TGGAGTCCCT AGAGGGCTTA CTAGAGAGCC CATCGCCTGG GACCTCCTGG 
ACCACCAGAA GCCAACTAGC CAACACAGAG CCCACCAAGG GCCTTCCAGA CCATCCATCC 
AGAAGCATGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HILPDA ( NM_013332.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_037464.1 Homo sapiens hypoxia inducible lipid droplet associated (HILPDA), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08913
Clone ID Related Accession (Same CDS sequence)	NM_001098786.1 , NM_013332.3 , NM_013332.4
Accession Version	NM_013332.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 192bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-31
Organism	Homo sapiens(human)
Product	hypoxia-inducible lipid droplet-associated protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CD686848.1, BC001863.1, AF144755.1 and BC008573.1. On Jun 20, 2007 this sequence version replaced NM_013332.2. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1163655.251736.1, SRR1163655.172413.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGAAGCATG TGTTGAACCT CTACCTGTTA GGTGTGGTAC TGACCCTACT CTCCATCTTC 
GTTAGAGTGA TGGAGTCCCT AGAGGGCTTA CTAGAGAGCC CATCGCCTGG GACCTCCTGG 
ACCACCAGAA GCCAACTAGC CAACACAGAG CCCACCAAGG GCCTTCCAGA CCATCCATCC 
AGAAGCATGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037464.1
CDS	263..454
Translation	MKHVLNLYLLGVVLTLLSIFVRVMESLEGLLESPSPGTSWTTRSQLANTEPTKGLPDHPSRSM

Target ORF information:

RefSeq Version	NM_013332.3
Organism	Homo sapiens(human)
Definition	Homo sapiens hypoxia inducible lipid droplet associated (HILPDA), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013332.3

ORF Insert Sequence:

ATGAAGCATG TGTTGAACCT CTACCTGTTA GGTGTGGTAC TGACCCTACT CTCCATCTTC 
GTTAGAGTGA TGGAGTCCCT AGAGGGCTTA CTAGAGAGCC CATCGCCTGG GACCTCCTGG 
ACCACCAGAA GCCAACTAGC CAACACAGAG CCCACCAAGG GCCTTCCAGA CCATCCATCC 
AGAAGCATGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

HILPDA ( NM_013332.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_037464.1 Homo sapiens hypoxia inducible lipid droplet associated (HILPDA), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu08913
Clone ID Related Accession (Same CDS sequence)	NM_001098786.1 , NM_013332.3 , NM_013332.4
Accession Version	NM_013332.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 192bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-03
Organism	Homo sapiens(human)
Product	hypoxia-inducible lipid droplet-associated protein
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CD686848.1, BC001863.1, AF144755.1 and BC008573.1. On Nov 22, 2018 this sequence version replaced NM_013332.3. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 both encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR5189652.100004.1, SRR1660805.143322.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000257696.5/ ENSP00000257696.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGAAGCATG TGTTGAACCT CTACCTGTTA GGTGTGGTAC TGACCCTACT CTCCATCTTC 
GTTAGAGTGA TGGAGTCCCT AGAGGGCTTA CTAGAGAGCC CATCGCCTGG GACCTCCTGG 
ACCACCAGAA GCCAACTAGC CAACACAGAG CCCACCAAGG GCCTTCCAGA CCATCCATCC 
AGAAGCATGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_037464.1
CDS	215..406
Translation	MKHVLNLYLLGVVLTLLSIFVRVMESLEGLLESPSPGTSWTTRSQLANTEPTKGLPDHPSRSM

Target ORF information:

RefSeq Version	NM_013332.4
Organism	Homo sapiens(human)
Definition	Homo sapiens hypoxia inducible lipid droplet associated (HILPDA), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_013332.4

ORF Insert Sequence:

ATGAAGCATG TGTTGAACCT CTACCTGTTA GGTGTGGTAC TGACCCTACT CTCCATCTTC 
GTTAGAGTGA TGGAGTCCCT AGAGGGCTTA CTAGAGAGCC CATCGCCTGG GACCTCCTGG 
ACCACCAGAA GCCAACTAGC CAACACAGAG CCCACCAAGG GCCTTCCAGA CCATCCATCC 
AGAAGCATGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Hypoxia Inducible Lipid Droplet Associated protein inhibits Adipose Triglyceride Lipase.
Journal of lipid research(2018 Jan)
Padmanabha Das KM,Wechselberger L,Liziczai M,De la Rosa Rodriguez M,Grabner GF,Heier C,Viertlmayr R,Radler C,Lichtenegger J,Zimmermann R,Borst JW,Zechner R,Kersten S,Oberer M

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HILPDA cDNA ORF clone, Homo sapiens(human)

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Related articles in PubMed

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Target ORF information:

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Target ORF information:

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Target ORF information:

Target ORF information:

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