The protein encoded by this gene belongs to the interalpha trypsin inhibitor heavy chain (ITIH) family. Interalpha trypsin inhibitor (ITI) is composed of two heavy chains (containing VWA domain) and one light chain. The light chain confers the protease-inhibitor function, while the heavy chains are involved in mediating protein-protein interactions with the components of the extracellular matrix. [provided by RefSeq, Sep 2009].
The following ITIH6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ITIH6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
inter-alpha-trypsin inhibitor heavy chain H6 precursor
Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AY358170.1 and CA413764.1. This sequence is a reference standard in the RefSeqGene project. On Jul 17, 2009 this sequence version replaced NM_198510.1.
Transcript exon combination :: AY358170.1 [ECO:0000332]
RNAseq introns :: mixed/partial sample support SAMEA1968832, SAMEA2142853 [ECO:0000350]
COMPLETENESS: complete on the 3' end.