×

KCNF1 cDNA ORF clone, Homo sapiens (human)

Gene Symbol KCNF1
Entrez Gene ID 3754
Full Name potassium channel, voltage gated modifier subfamily F, member 1
Synonyms IK8, KCNF, KV5.1, kH1
General protein information
Preferred Names
potassium voltage-gated channel subfamily F member 1
Names
potassium voltage-gated channel subfamily F member 1
potassium channel KH1
potassium channel Kv5.1
voltage-gated potassium channel subunit Kv5.1
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

2

2p25

Summary Voltage-gated potassium (Kv) channels represent the most complex class of voltage-gated ion channels from both functional and structural standpoints. Their diverse functions include regulating neurotransmitter release, heart rate, insulin secretion, neuronal excitability, epithelial electrolyte transport, smooth muscle contraction, and cell volume. This gene encodes a member of the potassium channel, voltage-gated, subfamily F. This gene is intronless and expressed in all tissues tested, including the heart, skeletal muscle, brain, kidney, and pancreas. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

603787


mRNA and Protein(s)

mRNA Protein Name
NM_002236 NP_002227 potassium voltage-gated channel subfamily F member 1



Homo sapiens (human) KCNF1 NP_002227.2
Pan troglodytes (chimpanzee) KCNF1 XP_003308941.1
Macaca mulatta (Rhesus monkey) KCNF1 XP_001087665.1
Canis lupus familiaris (dog) KCNF1 XP_540081.1
Bos taurus (cattle) KCNF1 NP_001091456.1
Mus musculus (house mouse) Kcnf1 NP_963289.2
Rattus norvegicus (Norway rat) Kcnf1 NP_001162575.1
Gallus gallus (chicken) KCNF1 XP_426210.2
Danio rerio (zebrafish) kcnf1b XP_005157014.1
Xenopus (Silurana) tropicalis (western clawed frog) kcnf1 NP_001096396.1


The following KCNF1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KCNF1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

Free ORF Clone
for Every Scientist
More Detail >>

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu31247 NM_002236 Homo sapiens potassium channel, voltage gated modifier subfamily F, member 1 (KCNF1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu31247
Clone ID Related Accession (Same CDS sequence) NM_002236
Accession Version NM_002236.4 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1485bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 18-JAN-2015
Organism Homo sapiens (human)
Product potassium voltage-gated channel subfamily F member 1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC026110.2. On Dec 31, 2002 this sequence version replaced gi:21314779. ##Evidence-Data-START## Transcript exon combination :: BC026110.2 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGACGGGT CCGGGGAGCG CAGCCTCCCG GAGCCGGGCA GCCAGAGCTC CGCTGCCAGC 
GACGACATAG AGATAGTCGT CAACGTGGGG GGCGTGCGGC AGGTGCTGTA CGGGGACCTC
CTCAGTCAGT ACCCTGAGAC CCGGCTGGCG GAGCTCATCA ACTGCTTGGC TGGGGGCTAC
GACACCATCT TCTCCCTGTG CGACGACTAC GACCCCGGCA AGCGCGAGTT CTACTTTGAC
AGGGACCCGG ACGCCTTCAA GTGTGTCATC GAGGTGTACT ATTTCGGGGA GGTCCACATG
AAGAAGGGCA TCTGCCCCAT CTGCTTCAAG AACGAGATGG ACTTCTGGAA GGTGGACCTC
AAGTTCCTGG ACGACTGTTG CAAGAGCCAC CTGAGCGAGA AGCGCGAGGA GCTGGAGGAG
ATCGCGCGCC GCGTGCAGCT CATCCTGGAC GACCTGGGCG TGGACGCAGC CGAGGGCCGC
TGGCGCCGCT GCCAGAAGTG CGTCTGGAAG TTCCTGGAGA AGCCCGAGTC GTCGTGCCCG
GCGCGGGTGG TGGCCGTGCT CTCCTTCCTG CTCATCCTCG TCTCGTCCGT GGTCATGTGC
ATGGGCACCA TCCCCGAGCT GCAGGTGCTG GACGCCGAGG GCAACCGCGT GGAGCACCCG
ACGCTGGAGA ACGTGGAGAC GGCGTGCATT GGCTGGTTCA CCCTGGAGTA CCTGCTGCGC
CTCTTCTCGT CACCCAACAA GCTGCACTTC GCGCTGTCCT TCATGAACAT TGTGGACGTG
CTGGCCATCC TCCCCTTCTA CGTGAGCCTC ACGCTCACGC ACCTGGGTGC CCGCATGATG
GAGCTGACCA ACGTGCAGCA GGCCGTGCAG GCGCTGCGGA TCATGCGCAT CGCGCGCATC
TTCAAGCTGG CCCGCCACTC CTCGGGCCTG CAGACCCTCA CCTATGCCCT CAAGCGCAGC
TTCAAGGAAC TGGGGCTGCT GCTCATGTAC CTGGCAGTGG GTATCTTCGT CTTCTCTGCC
CTGGGCTACA CCATGGAGCA GAGCCATCCA GAGACCCTGT TTAAGAGCAT CCCCCAGTCC
TTCTGGTGGG CCATCATCAC CATGACCACC GTCGGCTACG GCGACATCTA CCCCAAGACC
ACGCTGGGCA AGCTCAACGC GGCCATCAGC TTCTTGTGTG GTGTCATCGC CATCGCCCTG
CCCATCCACC CCATCATCAA CAACTTTGTC AGGTACTACA ACAAGCAGCG CGTCCTGGAG
ACCGCGGCCA AGCACGAGCT GGAGCTGATG GAACTCAACT CCAGCAGCGG GGGCGAGGGC
AAGACCGGGG GCTCCCGCAG TGACCTGGAC AACCTCCCTC CAGAGCCTGC GGGGAAGGAG
GCGCCGAGCT GCAGCAGCCG GCTGAAGCTC TCCCACAGCG ACACCTTCAT CCCCCTCCTG
ACCGAGGAGA AGCACCACAG GACCCGGCTC CAGAGTTGCA AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_002227.2
CDS491..1975
Misc Feature(1)347..349(+)
Misc Feature(2)563..868(+)
Misc Feature(3)1040..1102(+)
Misc Feature(4)1160..1222(+)
Misc Feature(5)1163..1696(+)
Misc Feature(6)1238..1300(+)
Misc Feature(7)1358..1420(+)
Misc Feature(8)1463..1525(+)
Misc Feature(9)1481..1690(+)
Misc Feature(10)1598..1615(+)
Misc Feature(11)1646..1708(+)
Exon (1)1..2289
Gene:KCNF1
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_002236
Organism Homo sapiens (human)
Definition Homo sapiens potassium channel, voltage gated modifier subfamily F, member 1 (KCNF1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_002236

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGGACGGGT CCGGGGAGCG CAGCCTCCCG GAGCCGGGCA GCCAGAGCTC CGCTGCCAGC 
GACGACATAG AGATAGTCGT CAACGTGGGG GGCGTGCGGC AGGTGCTGTA CGGGGACCTC
CTCAGTCAGT ACCCTGAGAC CCGGCTGGCG GAGCTCATCA ACTGCTTGGC TGGGGGCTAC
GACACCATCT TCTCCCTGTG CGACGACTAC GACCCCGGCA AGCGCGAGTT CTACTTTGAC
AGGGACCCGG ACGCCTTCAA GTGTGTCATC GAGGTGTACT ATTTCGGGGA GGTCCACATG
AAGAAGGGCA TCTGCCCCAT CTGCTTCAAG AACGAGATGG ACTTCTGGAA GGTGGACCTC
AAGTTCCTGG ACGACTGTTG CAAGAGCCAC CTGAGCGAGA AGCGCGAGGA GCTGGAGGAG
ATCGCGCGCC GCGTGCAGCT CATCCTGGAC GACCTGGGCG TGGACGCAGC CGAGGGCCGC
TGGCGCCGCT GCCAGAAGTG CGTCTGGAAG TTCCTGGAGA AGCCCGAGTC GTCGTGCCCG
GCGCGGGTGG TGGCCGTGCT CTCCTTCCTG CTCATCCTCG TCTCGTCCGT GGTCATGTGC
ATGGGCACCA TCCCCGAGCT GCAGGTGCTG GACGCCGAGG GCAACCGCGT GGAGCACCCG
ACGCTGGAGA ACGTGGAGAC GGCGTGCATT GGCTGGTTCA CCCTGGAGTA CCTGCTGCGC
CTCTTCTCGT CACCCAACAA GCTGCACTTC GCGCTGTCCT TCATGAACAT TGTGGACGTG
CTGGCCATCC TCCCCTTCTA CGTGAGCCTC ACGCTCACGC ACCTGGGTGC CCGCATGATG
GAGCTGACCA ACGTGCAGCA GGCCGTGCAG GCGCTGCGGA TCATGCGCAT CGCGCGCATC
TTCAAGCTGG CCCGCCACTC CTCGGGCCTG CAGACCCTCA CCTATGCCCT CAAGCGCAGC
TTCAAGGAAC TGGGGCTGCT GCTCATGTAC CTGGCAGTGG GTATCTTCGT CTTCTCTGCC
CTGGGCTACA CCATGGAGCA GAGCCATCCA GAGACCCTGT TTAAGAGCAT CCCCCAGTCC
TTCTGGTGGG CCATCATCAC CATGACCACC GTCGGCTACG GCGACATCTA CCCCAAGACC
ACGCTGGGCA AGCTCAACGC GGCCATCAGC TTCTTGTGTG GTGTCATCGC CATCGCCCTG
CCCATCCACC CCATCATCAA CAACTTTGTC AGGTACTACA ACAAGCAGCG CGTCCTGGAG
ACCGCGGCCA AGCACGAGCT GGAGCTGATG GAACTCAACT CCAGCAGCGG GGGCGAGGGC
AAGACCGGGG GCTCCCGCAG TGACCTGGAC AACCTCCCTC CAGAGCCTGC GGGGAAGGAG
GCGCCGAGCT GCAGCAGCCG GCTGAAGCTC TCCCACAGCG ACACCTTCAT CCCCCTCCTG
ACCGAGGAGA AGCACCACAG GACCCGGCTC CAGAGTTGCA AGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

International Union of Pharmacology. LIII. Nomenclature and molecular relationships of voltage-gated potassium channels
Pharmacol. Rev. 57 (4), 473-508 (2005)
Gutman GA, Chandy KG, Grissmer S, Lazdunski M, McKinnon D, Pardo LA, Robertson GA, Rudy B, Sanguinetti MC, Stuhmer W and Wang X.


book

Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome
Proc. Natl. Acad. Sci. U.S.A. 99 (12), 7986-7991 (2002)
Ottschytsch N, Raes A, Van Hoorick D and Snyders DJ.


book

Isolation, characterization, and mapping of two human potassium channels
Biochem. Biophys. Res. Commun. 241 (3), 675-681 (1997)
Su K, Kyaw H, Fan P, Zeng Z, Shell BK, Carter KC and Li Y.


 
*
*
*
*