Gene Symbol | SPINT4 |
Entrez Gene ID | 391253 |
Full Name | serine peptidase inhibitor, Kunitz type 4 |
Synonyms | C20orf137,SPINT3,dJ601O1.1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
ORF » Species Summary » Homo sapiens » SPINT4 cDNA ORF clone
gRNAs
Gene Symbol | SPINT4 |
Entrez Gene ID | 391253 |
Full Name | serine peptidase inhibitor, Kunitz type 4 |
Synonyms | C20orf137,SPINT3,dJ601O1.1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_178455.3 | NP_848550.1 | kunitz-type protease inhibitor 4 precursor |
NM_178455.1 | NP_848550.1 | kunitz-type protease inhibitor 4 precursor |
NM_178455.2 | NP_848550.1 | kunitz-type protease inhibitor 4 precursor |
Three genes expressing Kunitz domains in the epididymis are related to genes of WFDC-type protease inhibitors and semen coagulum proteins in spite of lacking similarity between their protein products.
Clauss A, Persson M, Lilja H, Lundwall ?
BMC biochemistry1255(2011 Oct)
Differing evolutionary histories of WFDC8 (short-term balancing) in Europeans and SPINT4 (incomplete selective sweep) in Africans.
Ferreira Z, Hurle B, Rocha J, Seixas S
Molecular biology and evolution28(10)2811-22(2011 Oct)
Transcriptome analysis of a cDNA library from adult human epididymis.
Li JY, Wang HY, Liu J, Liu Q, Zhang JS, Wan FC, Liu FJ, Jin SH, Zhang YL
DNA research : an international journal for rapid publication of reports on genes and genomes15(3)115-22(2008 Jun)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
We propose that the evolution of WFDC8 and SPINT4 has been shaped by complex selective scenarios due to the interdependence of variant fitness and ecological variables.
Title: Differing evolutionary histories of WFDC8 (short-term balancing) in Europeans and SPINT4 (incomplete selective sweep) in Africans.
The following SPINT4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SPINT4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu30107![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_178455.3 , NM_178455.1 , NM_178455.2 | |
Accession Version | NM_178455.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-20 | |
Organism | Homo sapiens(human) | |
Product | kunitz-type protease inhibitor 4 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CO408459.1, AY372173.1, AW303354.1 and AL109656.12. On May 17, 2019 this sequence version replaced NM_178455.2. ##Evidence-Data-START## Transcript exon combination :: AW303354.1, AY372174.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000279058.4/ ENSP00000279058.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAAGTCTG CCAAGCTGGG ATTTCTTCTA AGATTCTTCA TCTTCTGCTC ATTGAATACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_848550.1 |
CDS | 22..321 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAAGTCTG CCAAGCTGGG ATTTCTTCTA AGATTCTTCA TCTTCTGCTC ATTGAATACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu30107![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_178455.3 , NM_178455.1 , NM_178455.2 | |
Accession Version | NM_178455.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-03-14 | |
Organism | Homo sapiens(Human) | |
Product | kunitz-type protease inhibitor 4 precursor | |
Comment |
1 | ATGAAGTCTG CCAAGCTGGG ATTTCTTCTA AGATTCTTCA TCTTCTGCTC ATTGAATACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_848550.1 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAAGTCTG CCAAGCTGGG ATTTCTTCTA AGATTCTTCA TCTTCTGCTC ATTGAATACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu30107![]() |
|
Clone ID Related Accession (Same CDS sequence) | NM_178455.3 , NM_178455.1 , NM_178455.2 | |
Accession Version | NM_178455.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-10-08 | |
Organism | Homo sapiens(human) | |
Product | kunitz-type protease inhibitor 4 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CO408459.1, AY372173.1, AW303354.1 and AL109656.12. On Nov 5, 2016 this sequence version replaced NM_178455.1. ##Evidence-Data-START## Transcript exon combination :: AW303354.1, AY372174.1 [ECO:0000332] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAAGTCTG CCAAGCTGGG ATTTCTTCTA AGATTCTTCA TCTTCTGCTC ATTGAATACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_848550.1 |
CDS | 34..333 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGAAGTCTG CCAAGCTGGG ATTTCTTCTA AGATTCTTCA TCTTCTGCTC ATTGAATACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Three genes expressing Kunitz domains in the epididymis are related to genes of WFDC-type protease inhibitors and semen coagulum proteins in spite of lacking similarity between their protein products. |
Differing evolutionary histories of WFDC8 (short-term balancing) in Europeans and SPINT4 (incomplete selective sweep) in Africans. |
Transcriptome analysis of a cDNA library from adult human epididymis. |