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RNASE13 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol RNASE13
Entrez Gene ID 440163
Full Name ribonuclease A family member 13 (inactive)
Synonyms HEL-S-86p,RAL1
General protein information
Preferred Names

ribonuclease A family member 13 (inactive)

Names

probable inactive ribonuclease-like protein 13
epididymis secretory sperm binding protein Li 86p
ribonuclease 13
ribonuclease A L1
ribonuclease, RNase A family, 13 (non-active)
ribonuclease-like protein 13
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

14

14q11.2

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_001012264.3 NP_001012264.1 probable inactive ribonuclease-like protein 13 precursor
NM_001012264.4 NP_001012264.1 probable inactive ribonuclease-like protein 13 precursor

Pathways from BioSystems


Homologies


Homo sapiens (human) RNASE13 NP_001012264.1
Pan troglodytes (chimpanzee) RNASE13 XP_001148573.1
Mus musculus (house mouse) Rnase13 NP_001011687.1
Rattus norvegicus (Norway rat) Rnase13 NP_001012231.1
Canis lupus familiaris (dog) RNASE13 XP_005629201.1
Bos taurus (cattle) RNASE13 NP_001098896.1
RNASE13 XP_001094063.1

Gene Ontology


Bibliography

Related articles in PubMed

Identification of EGFLAM, SPATC1L and RNASE13 as novel susceptibility loci for aortic aneurysm in Japanese individuals by exome-wide association studies.
Yamada Y, Sakuma J, Takeuchi I, Yasukochi Y, Kato K, Oguri M, Fujimaki T, Horibe H, Muramatsu M, Sawabe M, Fujiwara Y, Taniguchi Y, Obuchi S, Kawai H, Shinkai S, Mori S, Arai T, Tanaka M
International journal of molecular medicine39(5)1091-1100(2017 May)

Comparative genomic analysis of eutherian ribonuclease A genes.
Premzl M
Molecular genetics and genomics : MGG289(2)161-7(2014 Apr)

The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories.
Cho S, Beintema JJ, Zhang J
Genomics85(2)208-20(2005 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

rs1465567 of EGFLAM and rs113710653 of SPATC1L may be susceptibility loci for true aortic aneurysm and rs143881017 of RNASE13 may be such a locus for dissecting aortic aneurysm in Japanese individuals.
Title: Identification of EGFLAM, SPATC1L and RNASE13 as novel susceptibility loci for aortic aneurysm in Japanese individuals by exome-wide association studies.

The following RNASE13 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RNASE13 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu25439 NM_001012264.4
Latest version!		 Homo sapiens ribonuclease A family member 13 (inactive) (RNASE13), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
View Old Accession Versions >>
OHu25439 NM_001012264.3 Homo sapiens ribonuclease A family member 13 (inactive) (RNASE13), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $49.50-$69.30
$99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu25439
Clone ID Related Accession (Same CDS sequence) NM_001012264.3 , NM_001012264.4
Accession Version NM_001012264.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 471bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-01
Organism Homo sapiens(human)
Product probable inactive ribonuclease-like protein 13 precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC044831.1, AY665808.1 and AL161668.6. On Oct 6, 2006 this sequence version replaced NM_001012264.2. ##Evidence-Data-START## Transcript exon combination :: BC044831.1, FJ237363.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMN02400288 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
ATGGCACCAG CTGTGACCCG GCTCCTTTTC CTCCAGCTTG TTCTGGGGCC AACTCTGGTC 
ATGGACATCA AGATGCAGAT TGGCAGCAGG AACTTCTATA CCTTAAGCAT TGACTATCCC 
AGGGTTAACT ACCCAAAGGG TTTCCGGGGC TATTGTAATG GTCTGATGTC CTATATGCGA 
GGCAAGATGC AAAATTCAGA TTGCCCAAAG ATCCATTATG TGATACATGC CCCTTGGAAG 
GCCATCCAGA AGTTCTGCAA GTATAGTGAC AGCTTCTGTG AGAATTACAA TGAATACTGC 
ACACTCACCC AGGATTCCCT CCCCATCACG GTCTGCTCCC TGAGCCACCA ACAGCCACCC 
ACTAGCTGCT ACTACAATAG CACCCTAACC AACCAGAAGC TCTACCTACT CTGCTCCCGC 
AAGTATGAAG CTGATCCAAT AGGTATCGCT GGTCTCTATT CGGGAATTTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001012264.1
CDS139..609
Translation

Target ORF information:

RefSeq Version NM_001012264.3
Organism Homo sapiens(human)
Definition Homo sapiens ribonuclease A family member 13 (inactive) (RNASE13), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001012264.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCACCAG CTGTGACCCG GCTCCTTTTC CTCCAGCTTG TTCTGGGGCC AACTCTGGTC 
ATGGACATCA AGATGCAGAT TGGCAGCAGG AACTTCTATA CCTTAAGCAT TGACTATCCC 
AGGGTTAACT ACCCAAAGGG TTTCCGGGGC TATTGTAATG GTCTGATGTC CTATATGCGA 
GGCAAGATGC AAAATTCAGA TTGCCCAAAG ATCCATTATG TGATACATGC CCCTTGGAAG 
GCCATCCAGA AGTTCTGCAA GTATAGTGAC AGCTTCTGTG AGAATTACAA TGAATACTGC 
ACACTCACCC AGGATTCCCT CCCCATCACG GTCTGCTCCC TGAGCCACCA ACAGCCACCC 
ACTAGCTGCT ACTACAATAG CACCCTAACC AACCAGAAGC TCTACCTACT CTGCTCCCGC 
AAGTATGAAG CTGATCCAAT AGGTATCGCT GGTCTCTATT CGGGAATTTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu25439
Clone ID Related Accession (Same CDS sequence) NM_001012264.3 , NM_001012264.4
Accession Version NM_001012264.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 471bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-30
Organism Homo sapiens(human)
Product probable inactive ribonuclease-like protein 13 precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL161668.6, BC044831.1 and AY665808.1. On Nov 22, 2018 this sequence version replaced NM_001012264.3. ##Evidence-Data-START## Transcript exon combination :: BC044831.1, FJ237363.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145893, SAMN02400288 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000382951.4/ ENSP00000372410.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
ATGGCACCAG CTGTGACCCG GCTCCTTTTC CTCCAGCTTG TTCTGGGGCC AACTCTGGTC 
ATGGACATCA AGATGCAGAT TGGCAGCAGG AACTTCTATA CCTTAAGCAT TGACTATCCC 
AGGGTTAACT ACCCAAAGGG TTTCCGGGGC TATTGTAATG GTCTGATGTC CTATATGCGA 
GGCAAGATGC AAAATTCAGA TTGCCCAAAG ATCCATTATG TGATACATGC CCCTTGGAAG 
GCCATCCAGA AGTTCTGCAA GTATAGTGAC AGCTTCTGTG AGAATTACAA TGAATACTGC 
ACACTCACCC AGGATTCCCT CCCCATCACG GTCTGCTCCC TGAGCCACCA ACAGCCACCC 
ACTAGCTGCT ACTACAATAG CACCCTAACC AACCAGAAGC TCTACCTACT CTGCTCCCGC 
AAGTATGAAG CTGATCCAAT AGGTATCGCT GGTCTCTATT CGGGAATTTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001012264.1
CDS161..631
Translation

Target ORF information:

RefSeq Version NM_001012264.4
Organism Homo sapiens(human)
Definition Homo sapiens ribonuclease A family member 13 (inactive) (RNASE13), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001012264.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGCACCAG CTGTGACCCG GCTCCTTTTC CTCCAGCTTG TTCTGGGGCC AACTCTGGTC 
ATGGACATCA AGATGCAGAT TGGCAGCAGG AACTTCTATA CCTTAAGCAT TGACTATCCC 
AGGGTTAACT ACCCAAAGGG TTTCCGGGGC TATTGTAATG GTCTGATGTC CTATATGCGA 
GGCAAGATGC AAAATTCAGA TTGCCCAAAG ATCCATTATG TGATACATGC CCCTTGGAAG 
GCCATCCAGA AGTTCTGCAA GTATAGTGAC AGCTTCTGTG AGAATTACAA TGAATACTGC 
ACACTCACCC AGGATTCCCT CCCCATCACG GTCTGCTCCC TGAGCCACCA ACAGCCACCC 
ACTAGCTGCT ACTACAATAG CACCCTAACC AACCAGAAGC TCTACCTACT CTGCTCCCGC 
AAGTATGAAG CTGATCCAAT AGGTATCGCT GGTCTCTATT CGGGAATTTA A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Identification of EGFLAM, SPATC1L and RNASE13 as novel susceptibility loci for aortic aneurysm in Japanese individuals by exome-wide association studies.
International journal of molecular medicine39(5)1091-1100(2017 May)
Yamada Y,Sakuma J,Takeuchi I,Yasukochi Y,Kato K,Oguri M,Fujimaki T,Horibe H,Muramatsu M,Sawabe M,Fujiwara Y,Taniguchi Y,Obuchi S,Kawai H,Shinkai S,Mori S,Arai T,Tanaka M


book

Comparative genomic analysis of eutherian ribonuclease A genes.
Molecular genetics and genomics : MGG289(2)161-7(2014 Apr)
Premzl M


book

The ribonuclease A superfamily of mammals and birds: identifying new members and tracing evolutionary histories.
Genomics85(2)208-20(2005 Feb)
Cho S,Beintema JJ,Zhang J