Gene Symbol | COA4 |
Entrez Gene ID | 51287 |
Full Name | cytochrome c oxidase assembly factor 4 homolog |
Synonyms | CHCHD8,CMC3,E2IG2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » COA4 cDNA ORF clone
Gene Symbol | COA4 |
Entrez Gene ID | 51287 |
Full Name | cytochrome c oxidase assembly factor 4 homolog |
Synonyms | CHCHD8,CMC3,E2IG2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
XM_017017884.1 | XP_016873373.1 | cytochrome c oxidase assembly factor 4 homolog, mitochondrial isoform X2 |
NM_016565.3 | NP_057649.2 | cytochrome c oxidase assembly factor 4 homolog, mitochondrial |
XM_017017883.1 | XP_016873372.1 | cytochrome c oxidase assembly factor 4 homolog, mitochondrial isoform X1 |
NM_016565.2 | NP_057649.2 | cytochrome c oxidase assembly factor 4 homolog, mitochondrial |
Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells.
Fischer M, Horn S, Belkacemi A, Kojer K, Petrungaro C, Habich M, Ali M, K?ttner V, Bien M, Kauff F, Dengjel J, Herrmann JM, Riemer J
Molecular biology of the cell24(14)2160-70(2013 Jul)
Analysis of Leigh syndrome mutations in the yeast SURF1 homolog reveals a new member of the cytochrome oxidase assembly factor family.
Bestwick M, Jeong MY, Khalimonchuk O, Kim H, Winge DR
Molecular and cellular biology30(18)4480-91(2010 Sep)
Effects of estrogen on global gene expression: identification of novel targets of estrogen action.
Charpentier AH, Bednarek AK, Daniel RL, Hawkins KA, Laflin KJ, Gaddis S, MacLeod MC, Aldaz CM
Cancer research60(21)5977-83(2000 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following COA4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the COA4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu07288 | |
Clone ID Related Accession (Same CDS sequence) | XM_017017884.1 , NM_016565.3 , NM_016565.2 | |
Accession Version | NM_016565.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 264bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-11-16 | |
Organism | Homo sapiens(human) | |
Product | cytochrome c oxidase assembly factor 4 homolog, mitochondrial | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP002770.3 and AK000434.1. On Nov 22, 2018 this sequence version replaced NM_016565.2. ##Evidence-Data-START## Transcript exon combination :: SRR1163658.464421.1, SRR5189667.154486.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000355693.5/ ENSP00000347919.4 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGTCAACCT CAGTCCCTCA AGGCCATACC TGGACCCAAC GGGTGAAGAA AGACGATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_057649.2 |
CDS | 107..370 |
Translation |
Target ORF information:
Target ORF information:
|
NM_016565.3 |
1 | ATGTCAACCT CAGTCCCTCA AGGCCATACC TGGACCCAAC GGGTGAAGAA AGACGATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu07288 | |
Clone ID Related Accession (Same CDS sequence) | XM_017017884.1 , NM_016565.3 , NM_016565.2 | |
Accession Version | NM_016565.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 264bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-09-30 | |
Organism | Homo sapiens(human) | |
Product | cytochrome c oxidase assembly factor 4 homolog, mitochondrial | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK000434.1. On Apr 5, 2004 this sequence version replaced NM_016565.1. ##Evidence-Data-START## Transcript exon combination :: AK000434.1, SRR1163655.305219.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968189, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTCAACCT CAGTCCCTCA AGGCCATACC TGGACCCAAC GGGTGAAGAA AGACGATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_057649.2 |
CDS | 106..369 |
Translation |
Target ORF information:
Target ORF information:
|
NM_016565.2 |
1 | ATGTCAACCT CAGTCCCTCA AGGCCATACC TGGACCCAAC GGGTGAAGAA AGACGATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu07288 | |
Clone ID Related Accession (Same CDS sequence) | XM_017017884.1 , NM_016565.3 , NM_016565.2 | |
Accession Version | XM_017017884.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 264bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | cytochrome c oxidase assembly factor 4 homolog, mitochondrial isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCAACCT CAGTCCCTCA AGGCCATACC TGGACCCAAC GGGTGAAGAA AGACGATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016873373.1 |
CDS | 259..522 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017017884.1 |
1 | ATGTCAACCT CAGTCCCTCA AGGCCATACC TGGACCCAAC GGGTGAAGAA AGACGATGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu92300 | |
Clone ID Related Accession (Same CDS sequence) | XM_017017883.1 | |
Accession Version | XM_017017883.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 291bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | cytochrome c oxidase assembly factor 4 homolog, mitochondrial isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTCTATA GACTCCCCAT CCCCAGGATG TCAACCTCAG TCCCTCAAGG CCATACCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016873372.1 |
CDS | 395..685 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017017883.1 |
1 | ATGTTCTATA GACTCCCCAT CCCCAGGATG TCAACCTCAG TCCCTCAAGG CCATACCTGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Protein import and oxidative folding in the mitochondrial intermembrane space of intact mammalian cells. |
Analysis of Leigh syndrome mutations in the yeast SURF1 homolog reveals a new member of the cytochrome oxidase assembly factor family. |
Effects of estrogen on global gene expression: identification of novel targets of estrogen action. |