×

PITX3 cDNA ORF clone, Homo sapiens (human)

Gene Symbol PITX3
Entrez Gene ID 5309
Full Name paired-like homeodomain 3
Synonyms ASMD, ASOD, CTPP4, CTRCT11, PTX3
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

10

10q24.32

Summary This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription factors. This protein is involved in lens formation during eye development. Mutations of this gene have been associated with anterior segment mesenchymal dysgenesis and congenital cataracts. [provided by RefSeq, Jul 2008]. lac of sum
Disorder MIM:

602669

Disorder Html: Anterior segment mesenchymal dysgenesis, 107250 (3); Cataract,

mRNA and Protein(s)

mRNA Protein Name
XM_011539865 XP_011538167 pituitary homeobox 3 isoform X1
NM_005029 NP_005020 pituitary homeobox 3


Homo sapiens (human) PITX3 NP_005020.1
Pan troglodytes (chimpanzee) PITX3 XP_521591.2
Canis lupus familiaris (dog) PITX3 XP_005637719.1
Bos taurus (cattle) PITX3 NP_001179234.1
Mus musculus (house mouse) Pitx3 NP_032878.1
Rattus norvegicus (Norway rat) Pitx3 NP_062120.1
Gallus gallus (chicken) PITX3 XP_421631.2
Danio rerio (zebrafish) pitx3 NP_991238.1
Xenopus (Silurana) tropicalis (western clawed frog) pitx3 XP_002935807.2


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following PITX3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PITX3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID RefSeq Accession Definition **Vector *Turnaround time Price Select
OHu59713 XM_011539865 PREDICTED: Homo sapiens paired-like homeodomain 3 (PITX3), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $139.30
$199.00
OHu18059 NM_005029 Homo sapiens paired-like homeodomain 3 (PITX3), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $216.30
$309.00
Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu59713
Clone ID Related Accession (Same CDS sequence) XM_011539865
Accession Version XM_011539865.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 927bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product pituitary homeobox 3 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_030059.14) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCAGAGCC CTCCCTCCAT GGAGTTCGGC CTGCTCAGCG AGGCAGAGGC CCGGAGCCCT 
GCCCTGTCGC TGTCAGACGC TGGCACTCCG CACCCCCAGC TCCCAGAGCA CGGCTGCAAG
GGCCAGGAGC ACAGCGACTC AGAAAAGGCC TCGGCTTCGC TGCCCGGCGG CTCCCCAGAG
GACGGTTCGC TGAAAAAGAA GCAGCGGCGG CAGCGCACGC ACTTCACCAG CCAGCAGCTA
CAGGAGCTAG AGGCGACCTT CCAGAGGAAC CGCTACCCCG ACATGAGCAC GCGCGAGGAG
ATCGCCGTGT GGACCAACCT CACCGAGGCC CGCGTGCGGG TGTGGTTCAA GAACCGGCGC
GCCAAATGGC GGAAGCGCGA GCGCAGCCAG CAGGCCGAGC TATGCAAAGG CAGCTTCGCG
GCGCCGCTCG GGGGGCTGGT GCCGCCCTAC GAGGAGGTGT ACCCCGGCTA CTCGTACGGC
AACTGGCCGC CCAAGGCTCT TGCCCCGCCG CTCGCCGCCA AGACCTTTCC ATTCGCCTTC
AACTCGGTCA ACGTGGGGCC TCTGGCTTCG CAGCCCGTCT TCTCGCCACC CAGCTCCATC
GCCGCCTCCA TGGTGCCCTC CGCCGCGGCT GCCCCGGGCA CCGTGCCAGG GCCTGGGGCC
CTGCAGGGCC TGGGCGGGGG CCCCCCCGGG CTGGCTCCGG CCGCCGTGTC CTCCGGGGCC
GTGTCCTGCC CTTATGCCTC GGCCGCCGCC GCCGCCGCGG CTGCCGCCTC TTCCCCCTAC
GTCTATCGGG ACCCGTGTAA CTCGAGCCTG GCCAGCCTGC GGCTCAAAGC CAAACAGCAC
GCCTCCTTCA GCTACCCCGC TGTGCACGGG CCGCCCCCGG CAGCCAACCT TAGTCCGTGC
CAGTACGCCG TGGAAAGGCC CGTATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011538167.1
CDS196..1122
Misc Feature(1)400..576(+)
Misc Feature(2)400..570(+)
Misc Feature(3)406..558(+)
Misc Feature(4)982..1038(+)
Translation

Target ORF information:

RefSeq Version XM_011539865
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens paired-like homeodomain 3 (PITX3), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011539865

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGCAGAGCC CTCCCTCCAT GGAGTTCGGC CTGCTCAGCG AGGCAGAGGC CCGGAGCCCT 
GCCCTGTCGC TGTCAGACGC TGGCACTCCG CACCCCCAGC TCCCAGAGCA CGGCTGCAAG
GGCCAGGAGC ACAGCGACTC AGAAAAGGCC TCGGCTTCGC TGCCCGGCGG CTCCCCAGAG
GACGGTTCGC TGAAAAAGAA GCAGCGGCGG CAGCGCACGC ACTTCACCAG CCAGCAGCTA
CAGGAGCTAG AGGCGACCTT CCAGAGGAAC CGCTACCCCG ACATGAGCAC GCGCGAGGAG
ATCGCCGTGT GGACCAACCT CACCGAGGCC CGCGTGCGGG TGTGGTTCAA GAACCGGCGC
GCCAAATGGC GGAAGCGCGA GCGCAGCCAG CAGGCCGAGC TATGCAAAGG CAGCTTCGCG
GCGCCGCTCG GGGGGCTGGT GCCGCCCTAC GAGGAGGTGT ACCCCGGCTA CTCGTACGGC
AACTGGCCGC CCAAGGCTCT TGCCCCGCCG CTCGCCGCCA AGACCTTTCC ATTCGCCTTC
AACTCGGTCA ACGTGGGGCC TCTGGCTTCG CAGCCCGTCT TCTCGCCACC CAGCTCCATC
GCCGCCTCCA TGGTGCCCTC CGCCGCGGCT GCCCCGGGCA CCGTGCCAGG GCCTGGGGCC
CTGCAGGGCC TGGGCGGGGG CCCCCCCGGG CTGGCTCCGG CCGCCGTGTC CTCCGGGGCC
GTGTCCTGCC CTTATGCCTC GGCCGCCGCC GCCGCCGCGG CTGCCGCCTC TTCCCCCTAC
GTCTATCGGG ACCCGTGTAA CTCGAGCCTG GCCAGCCTGC GGCTCAAAGC CAAACAGCAC
GCCTCCTTCA GCTACCCCGC TGTGCACGGG CCGCCCCCGG CAGCCAACCT TAGTCCGTGC
CAGTACGCCG TGGAAAGGCC CGTATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu18059
Clone ID Related Accession (Same CDS sequence) NM_005029
Accession Version NM_005029.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 909bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product pituitary homeobox 3
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from BC011642.2. This sequence is a reference standard in the RefSeqGene project. On Oct 22, 2002 this sequence version replaced gi:21361258. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC011642.2, CD675151.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA962332, SAMEA962347 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGAGTTCG GCCTGCTCAG CGAGGCAGAG GCCCGGAGCC CTGCCCTGTC GCTGTCAGAC 
GCTGGCACTC CGCACCCCCA GCTCCCAGAG CACGGCTGCA AGGGCCAGGA GCACAGCGAC
TCAGAAAAGG CCTCGGCTTC GCTGCCCGGC GGCTCCCCAG AGGACGGTTC GCTGAAAAAG
AAGCAGCGGC GGCAGCGCAC GCACTTCACC AGCCAGCAGC TACAGGAGCT AGAGGCGACC
TTCCAGAGGA ACCGCTACCC CGACATGAGC ACGCGCGAGG AGATCGCCGT GTGGACCAAC
CTCACCGAGG CCCGCGTGCG GGTGTGGTTC AAGAACCGGC GCGCCAAATG GCGGAAGCGC
GAGCGCAGCC AGCAGGCCGA GCTATGCAAA GGCAGCTTCG CGGCGCCGCT CGGGGGGCTG
GTGCCGCCCT ACGAGGAGGT GTACCCCGGC TACTCGTACG GCAACTGGCC GCCCAAGGCT
CTTGCCCCGC CGCTCGCCGC CAAGACCTTT CCATTCGCCT TCAACTCGGT CAACGTGGGG
CCTCTGGCTT CGCAGCCCGT CTTCTCGCCA CCCAGCTCCA TCGCCGCCTC CATGGTGCCC
TCCGCCGCGG CTGCCCCGGG CACCGTGCCA GGGCCTGGGG CCCTGCAGGG CCTGGGCGGG
GGCCCCCCCG GGCTGGCTCC GGCCGCCGTG TCCTCCGGGG CCGTGTCCTG CCCTTATGCC
TCGGCCGCCG CCGCCGCCGC GGCTGCCGCC TCTTCCCCCT ACGTCTATCG GGACCCGTGT
AACTCGAGCC TGGCCAGCCT GCGGCTCAAA GCCAAACAGC ACGCCTCCTT CAGCTACCCC
GCTGTGCACG GGCCGCCCCC GGCAGCCAAC CTTAGTCCGT GCCAGTACGC CGTGGAAAGG
CCCGTATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_005020.1
CDS155..1063
Misc Feature(1)89..91(+)
Misc Feature(2)341..517(+)
Misc Feature(3)341..511(+)
Misc Feature(4)347..499(+)
Misc Feature(5)923..979(+)
Misc Feature(6)938..979(+)
Misc Feature(7)956..970(+)
Exon (1)1..142
Gene:PITX3
Gene Synonym:
Exon (2)143..272
Gene:PITX3
Gene Synonym:
Exon (3)273..475
Gene:PITX3
Gene Synonym:
Exon (4)476..1388
Gene:PITX3
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_005029
Organism Homo sapiens (human)
Definition Homo sapiens paired-like homeodomain 3 (PITX3), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_005029

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
ATGGAGTTCG GCCTGCTCAG CGAGGCAGAG GCCCGGAGCC CTGCCCTGTC GCTGTCAGAC 
GCTGGCACTC CGCACCCCCA GCTCCCAGAG CACGGCTGCA AGGGCCAGGA GCACAGCGAC
TCAGAAAAGG CCTCGGCTTC GCTGCCCGGC GGCTCCCCAG AGGACGGTTC GCTGAAAAAG
AAGCAGCGGC GGCAGCGCAC GCACTTCACC AGCCAGCAGC TACAGGAGCT AGAGGCGACC
TTCCAGAGGA ACCGCTACCC CGACATGAGC ACGCGCGAGG AGATCGCCGT GTGGACCAAC
CTCACCGAGG CCCGCGTGCG GGTGTGGTTC AAGAACCGGC GCGCCAAATG GCGGAAGCGC
GAGCGCAGCC AGCAGGCCGA GCTATGCAAA GGCAGCTTCG CGGCGCCGCT CGGGGGGCTG
GTGCCGCCCT ACGAGGAGGT GTACCCCGGC TACTCGTACG GCAACTGGCC GCCCAAGGCT
CTTGCCCCGC CGCTCGCCGC CAAGACCTTT CCATTCGCCT TCAACTCGGT CAACGTGGGG
CCTCTGGCTT CGCAGCCCGT CTTCTCGCCA CCCAGCTCCA TCGCCGCCTC CATGGTGCCC
TCCGCCGCGG CTGCCCCGGG CACCGTGCCA GGGCCTGGGG CCCTGCAGGG CCTGGGCGGG
GGCCCCCCCG GGCTGGCTCC GGCCGCCGTG TCCTCCGGGG CCGTGTCCTG CCCTTATGCC
TCGGCCGCCG CCGCCGCCGC GGCTGCCGCC TCTTCCCCCT ACGTCTATCG GGACCCGTGT
AACTCGAGCC TGGCCAGCCT GCGGCTCAAA GCCAAACAGC ACGCCTCCTT CAGCTACCCC
GCTGTGCACG GGCCGCCCCC GGCAGCCAAC CTTAGTCCGT GCCAGTACGC CGTGGAAAGG
CCCGTATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
*
*
*
*