YTHDF1 cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Gene Symbol	YTHDF1
Entrez Gene ID	54915
Full Name	YTH N6-methyladenosine RNA binding protein 1
Synonyms	C20orf21
General protein information	Preferred Names YTH N6-methyladenosine RNA binding protein 1 Names YTH domain-containing family protein 1 DACA-1 YTH N(6)-methyladenosine RNA binding protein 1 YTH domain family 1 YTH domain family protein 1 YTH domain family, member 1 dermatomyositis associated with cancer putative autoantigen 1
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 20 Map Location: 20q13.33
Disorder MIM:	616529

mRNA and Protein(s)

mRNA	Protein	Name
NM_017798.3	NP_060268.2	YTH domain-containing family protein 1
NM_017798.4	NP_060268.2	YTH domain-containing family protein 1
XM_024451914.1	XP_024307682.1	YTH domain-containing family protein 1 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Ythdf1	NP_001019927.1
Gallus gallus (chicken)	YTHDF1	NP_001012851.1
Danio rerio (zebrafish)	ythdf1	NP_997878.1
Xenopus tropicalis (tropical clawed frog)	ythdf1	NP_989392.1
	YTHDF1	XP_002798106.1
Mus musculus (house mouse)	Ythdf1	NP_776122.1
Pan troglodytes (chimpanzee)	YTHDF1	XP_003317109.1
Canis lupus familiaris (dog)	YTHDF1	XP_005635335.1
Homo sapiens (human)	YTHDF1	NP_060268.2
Bos taurus (cattle)	YTHDF1	NP_001178345.1

Gene Ontology
Bibliography

Related articles in PubMed

YTHDF3 facilitates translation and decay of N
Shi H, Wang X, Lu Z, Zhao BS, Ma H, Hsu PJ, Liu C, He C
Cell research27(3)315-328(2017 Mar)

Cytoplasmic m
Li A, Chen YS, Ping XL, Yang X, Xiao W, Yang Y, Sun HY, Zhu Q, Baidya P, Wang X, Bhattarai DP, Zhao YL, Sun BF, Yang YG
Cell research27(3)444-447(2017 Mar)

N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression.
Tirumuru N, Zhao BS, Lu W, Lu Z, He C, Wu L
eLife5(2016 07)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The authors found that the overexpression of YTHDF proteins in cells inhibited HIV-1 infection mainly by decreasing HIV-1 reverse transcription, while knockdown of YTHDF1-3 in cells had the opposite effects. Moreover, silencing the N(6)-methyladenosine writers decreased HIV-1 Gag protein expression in virus-producing cells, while silencing the N(6)-methyladenosine erasers increased Gag expression.
Title: N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression.

binding affinities of the YTH domains of three human proteins and yeast YTH domain protein Pho92
Title: Structural Basis for the Discriminative Recognition of N6-Methyladenosine RNA by the Human YT521-B Homology Domain Family of Proteins.

The following YTHDF1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the YTHDF1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OHu08855	NM_017798.4 Latest version!	Homo sapiens YTH N6-methyladenosine RNA binding protein 1 (YTHDF1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
OHu105123	XM_024451914.1 Latest version!	Homo sapiens YTH N6-methyladenosine RNA binding protein 1 (YTHDF1), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OHu08855	NM_017798.3	Homo sapiens YTH N6-methyladenosine RNA binding protein 1 (YTHDF1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	in pcDNA3.1-C-(k)DYK	$189.50-$265.30 $379.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

YTHDF1 ( NM_017798.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_060268.2 Homo sapiens YTH N6-methyladenosine RNA binding protein 1 (YTHDF1), mRNA.

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CloneID	OHu08855
Clone ID Related Accession (Same CDS sequence)	NM_017798.3 , NM_017798.4
Accession Version	NM_017798.3	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-12-05
Organism	Homo sapiens(human)
Product	YTH domain-containing family protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC050284.1 and BC003681.1. On Oct 11, 2008 this sequence version replaced NM_017798.2. ##Evidence-Data-START## Transcript exon combination :: BC050284.1, SRR1163655.119553.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END##

ATGTCGGCCA CCAGCGTGGA CACCCAGAGA ACAAAAGGAC AAGATAATAA AGTACAAAAT 
GGTTCGTTAC ATCAGAAGGA TACAGTTCAT GACAATGACT TTGAGCCCTA CCTTACTGGA 
CAGTCAAATC AGAGTAACAG TTACCCCTCA ATGAGCGACC CCTACCTGTC CAGCTATTAC 
CCGCCGTCCA TTGGATTTCC TTACTCCCTC AATGAGGCTC CGTGGTCTAC TGCAGGGGAC 
CCTCCGATTC CATACCTCAC CACCTACGGA CAGCTCAGTA ACGGAGACCA TCATTTTATG 
CACGATGCTG TTTTTGGGCA GCCTGGGGGC CTGGGGAACA ACATCTATCA GCACAGGTTC 
AATTTTTTCC CTGAAAACCC TGCGTTCTCA GCATGGGGGA CAAGTGGGTC TCAAGGTCAG 
CAGACCCAGA GCTCCGCGTA TGGGAGCAGC TACACCTACC CCCCGAGCTC CCTGGGTGGC 
ACGGTGGTTG ATGGGCAGCC AGGCTTTCAC AGCGACACCC TCAGCAAGGC CCCCGGGATG 
AACAGCCTGG AGCAGGGCAT GGTTGGCCTG AAGATTGGGG ACGTCAGCTC CTCCGCCGTC 
AAGACGGTGG GCTCTGTCGT CAGCAGCGTG GCACTGACTG GTGTCCTTTC TGGCAACGGT 
GGGACAAATG TGAACATGCC AGTTTCAAAG CCGACCTCGT GGGCTGCCAT TGCCAGCAAG 
CCTGCAAAAC CACAGCCTAA AATGAAAACA AAGAGCGGGC CTGTCATGGG GGGTGGGCTG 
CCCCCTCCAC CCATAAAGCA TAACATGGAC ATTGGCACCT GGGATAACAA GGGGCCTGTG 
CCGAAGGCCC CAGTCCCCCA GCAGGCACCC TCTCCACAGG CTGCCCCACA GCCCCAGCAG 
GTGGCTCAGC CTCTCCCAGC ACAGCCCCCA GCTTTGGCTC AACCGCAGTA TCAGAGCCCT 
CAGCAGCCAC CCCAGACCCG CTGGGTTGCC CCACGCAACA GAAACGCGGC GTTTGGGCAG 
AGCGGAGGGG CTGGCAGCGA TAGCAACTCT CCTGGAAACG TCCAGCCTAA TTCTGCCCCC 
AGCGTCGAAT CCCACCCCGT CCTTGAAAAA CTGAAGGCTG CTCACAGCTA CAACCCGAAA 
GAGTTTGAGT GGAATCTGAA AAGCGGGCGT GTGTTCATCA TCAAGAGCTA CTCTGAGGAC 
GACATCCACC GCTCCATTAA GTACTCCATC TGGTGTAGCA CAGAGCACGG CAACAAGCGC 
CTGGACAGCG CCTTCCGCTG CATGAGCAGC AAGGGGCCCG TCTACCTGCT CTTCAGCGTC 
AATGGGAGTG GGCATTTTTG TGGGGTGGCC GAGATGAAGT CCCCCGTGGA CTACGGCACC 
AGTGCCGGGG TCTGGTCTCA GGACAAGTGG AAGGGGAAGT TTGATGTCCA GTGGATTTTT 
GTTAAGGATG TACCCAATAA CCAGCTCCGG CACATCAGGC TGGAGAATAA CGACAACAAA 
CCGGTCACAA ACTCCCGGGA CACCCAGGAG GTGCCCTTAG AAAAAGCCAA GCAAGTGCTG 
AAAATTATCA GTTCCTACAA GCACACAACC TCCATCTTCG ACGACTTTGC TCACTACGAG 
AAGCGCCAGG AGGAGGAGGA GGTGGTGCGC AAGGAACGGC AGAGTCGAAA CAAACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060268.2
CDS	295..1974
Translation	MSATSVDTQRTKGQDNKVQNGSLHQKDTVHDNDFEPYLTGQSNQSNSYPSMSDPYLSSYYPPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIYQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLSKAPGMNSLEQGMVGLKIGDVSSSAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQPNSAPSVESHPVLEKLKAAHSYNPKEFEWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKGPVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVQWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIISSYKHTTSIFDDFAHYEKRQEEEEVVRKERQSRNKQ

Target ORF information:

RefSeq Version	NM_017798.3
Organism	Homo sapiens(human)
Definition	Homo sapiens YTH N6-methyladenosine RNA binding protein 1 (YTHDF1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017798.3

ORF Insert Sequence:

ATGTCGGCCA CCAGCGTGGA CACCCAGAGA ACAAAAGGAC AAGATAATAA AGTACAAAAT 
GGTTCGTTAC ATCAGAAGGA TACAGTTCAT GACAATGACT TTGAGCCCTA CCTTACTGGA 
CAGTCAAATC AGAGTAACAG TTACCCCTCA ATGAGCGACC CCTACCTGTC CAGCTATTAC 
CCGCCGTCCA TTGGATTTCC TTACTCCCTC AATGAGGCTC CGTGGTCTAC TGCAGGGGAC 
CCTCCGATTC CATACCTCAC CACCTACGGA CAGCTCAGTA ACGGAGACCA TCATTTTATG 
CACGATGCTG TTTTTGGGCA GCCTGGGGGC CTGGGGAACA ACATCTATCA GCACAGGTTC 
AATTTTTTCC CTGAAAACCC TGCGTTCTCA GCATGGGGGA CAAGTGGGTC TCAAGGTCAG 
CAGACCCAGA GCTCCGCGTA TGGGAGCAGC TACACCTACC CCCCGAGCTC CCTGGGTGGC 
ACGGTGGTTG ATGGGCAGCC AGGCTTTCAC AGCGACACCC TCAGCAAGGC CCCCGGGATG 
AACAGCCTGG AGCAGGGCAT GGTTGGCCTG AAGATTGGGG ACGTCAGCTC CTCCGCCGTC 
AAGACGGTGG GCTCTGTCGT CAGCAGCGTG GCACTGACTG GTGTCCTTTC TGGCAACGGT 
GGGACAAATG TGAACATGCC AGTTTCAAAG CCGACCTCGT GGGCTGCCAT TGCCAGCAAG 
CCTGCAAAAC CACAGCCTAA AATGAAAACA AAGAGCGGGC CTGTCATGGG GGGTGGGCTG 
CCCCCTCCAC CCATAAAGCA TAACATGGAC ATTGGCACCT GGGATAACAA GGGGCCTGTG 
CCGAAGGCCC CAGTCCCCCA GCAGGCACCC TCTCCACAGG CTGCCCCACA GCCCCAGCAG 
GTGGCTCAGC CTCTCCCAGC ACAGCCCCCA GCTTTGGCTC AACCGCAGTA TCAGAGCCCT 
CAGCAGCCAC CCCAGACCCG CTGGGTTGCC CCACGCAACA GAAACGCGGC GTTTGGGCAG 
AGCGGAGGGG CTGGCAGCGA TAGCAACTCT CCTGGAAACG TCCAGCCTAA TTCTGCCCCC 
AGCGTCGAAT CCCACCCCGT CCTTGAAAAA CTGAAGGCTG CTCACAGCTA CAACCCGAAA 
GAGTTTGAGT GGAATCTGAA AAGCGGGCGT GTGTTCATCA TCAAGAGCTA CTCTGAGGAC 
GACATCCACC GCTCCATTAA GTACTCCATC TGGTGTAGCA CAGAGCACGG CAACAAGCGC 
CTGGACAGCG CCTTCCGCTG CATGAGCAGC AAGGGGCCCG TCTACCTGCT CTTCAGCGTC 
AATGGGAGTG GGCATTTTTG TGGGGTGGCC GAGATGAAGT CCCCCGTGGA CTACGGCACC 
AGTGCCGGGG TCTGGTCTCA GGACAAGTGG AAGGGGAAGT TTGATGTCCA GTGGATTTTT 
GTTAAGGATG TACCCAATAA CCAGCTCCGG CACATCAGGC TGGAGAATAA CGACAACAAA 
CCGGTCACAA ACTCCCGGGA CACCCAGGAG GTGCCCTTAG AAAAAGCCAA GCAAGTGCTG 
AAAATTATCA GTTCCTACAA GCACACAACC TCCATCTTCG ACGACTTTGC TCACTACGAG 
AAGCGCCAGG AGGAGGAGGA GGTGGTGCGC AAGGAACGGC AGAGTCGAAA CAAACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

YTHDF1 ( NM_017798.4 ) cDNA ORF clone, Homo sapiens(human) -> NP_060268.2 Homo sapiens YTH N6-methyladenosine RNA binding protein 1 (YTHDF1), mRNA.

Price & Availability↑

CloneID	OHu08855
Clone ID Related Accession (Same CDS sequence)	NM_017798.3 , NM_017798.4
Accession Version	NM_017798.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-26
Organism	Homo sapiens(human)
Product	YTH domain-containing family protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC050284.1 and BC003681.1. On Nov 23, 2018 this sequence version replaced NM_017798.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC050284.1, SRR1163655.119553.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000370339.8/ ENSP00000359364.3 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length.

ATGTCGGCCA CCAGCGTGGA CACCCAGAGA ACAAAAGGAC AAGATAATAA AGTACAAAAT 
GGTTCGTTAC ATCAGAAGGA TACAGTTCAT GACAATGACT TTGAGCCCTA CCTTACTGGA 
CAGTCAAATC AGAGTAACAG TTACCCCTCA ATGAGCGACC CCTACCTGTC CAGCTATTAC 
CCGCCGTCCA TTGGATTTCC TTACTCCCTC AATGAGGCTC CGTGGTCTAC TGCAGGGGAC 
CCTCCGATTC CATACCTCAC CACCTACGGA CAGCTCAGTA ACGGAGACCA TCATTTTATG 
CACGATGCTG TTTTTGGGCA GCCTGGGGGC CTGGGGAACA ACATCTATCA GCACAGGTTC 
AATTTTTTCC CTGAAAACCC TGCGTTCTCA GCATGGGGGA CAAGTGGGTC TCAAGGTCAG 
CAGACCCAGA GCTCCGCGTA TGGGAGCAGC TACACCTACC CCCCGAGCTC CCTGGGTGGC 
ACGGTGGTTG ATGGGCAGCC AGGCTTTCAC AGCGACACCC TCAGCAAGGC CCCCGGGATG 
AACAGCCTGG AGCAGGGCAT GGTTGGCCTG AAGATTGGGG ACGTCAGCTC CTCCGCCGTC 
AAGACGGTGG GCTCTGTCGT CAGCAGCGTG GCACTGACTG GTGTCCTTTC TGGCAACGGT 
GGGACAAATG TGAACATGCC AGTTTCAAAG CCGACCTCGT GGGCTGCCAT TGCCAGCAAG 
CCTGCAAAAC CACAGCCTAA AATGAAAACA AAGAGCGGGC CTGTCATGGG GGGTGGGCTG 
CCCCCTCCAC CCATAAAGCA TAACATGGAC ATTGGCACCT GGGATAACAA GGGGCCTGTG 
CCGAAGGCCC CAGTCCCCCA GCAGGCACCC TCTCCACAGG CTGCCCCACA GCCCCAGCAG 
GTGGCTCAGC CTCTCCCAGC ACAGCCCCCA GCTTTGGCTC AACCGCAGTA TCAGAGCCCT 
CAGCAGCCAC CCCAGACCCG CTGGGTTGCC CCACGCAACA GAAACGCGGC GTTTGGGCAG 
AGCGGAGGGG CTGGCAGCGA TAGCAACTCT CCTGGAAACG TCCAGCCTAA TTCTGCCCCC 
AGCGTCGAAT CCCACCCCGT CCTTGAAAAA CTGAAGGCTG CTCACAGCTA CAACCCGAAA 
GAGTTTGAGT GGAATCTGAA AAGCGGGCGT GTGTTCATCA TCAAGAGCTA CTCTGAGGAC 
GACATCCACC GCTCCATTAA GTACTCCATC TGGTGTAGCA CAGAGCACGG CAACAAGCGC 
CTGGACAGCG CCTTCCGCTG CATGAGCAGC AAGGGGCCCG TCTACCTGCT CTTCAGCGTC 
AATGGGAGTG GGCATTTTTG TGGGGTGGCC GAGATGAAGT CCCCCGTGGA CTACGGCACC 
AGTGCCGGGG TCTGGTCTCA GGACAAGTGG AAGGGGAAGT TTGATGTCCA GTGGATTTTT 
GTTAAGGATG TACCCAATAA CCAGCTCCGG CACATCAGGC TGGAGAATAA CGACAACAAA 
CCGGTCACAA ACTCCCGGGA CACCCAGGAG GTGCCCTTAG AAAAAGCCAA GCAAGTGCTG 
AAAATTATCA GTTCCTACAA GCACACAACC TCCATCTTCG ACGACTTTGC TCACTACGAG 
AAGCGCCAGG AGGAGGAGGA GGTGGTGCGC AAGGAACGGC AGAGTCGAAA CAAACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_060268.2
CDS	240..1919
Translation	MSATSVDTQRTKGQDNKVQNGSLHQKDTVHDNDFEPYLTGQSNQSNSYPSMSDPYLSSYYPPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIYQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLSKAPGMNSLEQGMVGLKIGDVSSSAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQPNSAPSVESHPVLEKLKAAHSYNPKEFEWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKGPVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVQWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIISSYKHTTSIFDDFAHYEKRQEEEEVVRKERQSRNKQ

Target ORF information:

RefSeq Version	NM_017798.4
Organism	Homo sapiens(human)
Definition	Homo sapiens YTH N6-methyladenosine RNA binding protein 1 (YTHDF1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_017798.4

ORF Insert Sequence:

ATGTCGGCCA CCAGCGTGGA CACCCAGAGA ACAAAAGGAC AAGATAATAA AGTACAAAAT 
GGTTCGTTAC ATCAGAAGGA TACAGTTCAT GACAATGACT TTGAGCCCTA CCTTACTGGA 
CAGTCAAATC AGAGTAACAG TTACCCCTCA ATGAGCGACC CCTACCTGTC CAGCTATTAC 
CCGCCGTCCA TTGGATTTCC TTACTCCCTC AATGAGGCTC CGTGGTCTAC TGCAGGGGAC 
CCTCCGATTC CATACCTCAC CACCTACGGA CAGCTCAGTA ACGGAGACCA TCATTTTATG 
CACGATGCTG TTTTTGGGCA GCCTGGGGGC CTGGGGAACA ACATCTATCA GCACAGGTTC 
AATTTTTTCC CTGAAAACCC TGCGTTCTCA GCATGGGGGA CAAGTGGGTC TCAAGGTCAG 
CAGACCCAGA GCTCCGCGTA TGGGAGCAGC TACACCTACC CCCCGAGCTC CCTGGGTGGC 
ACGGTGGTTG ATGGGCAGCC AGGCTTTCAC AGCGACACCC TCAGCAAGGC CCCCGGGATG 
AACAGCCTGG AGCAGGGCAT GGTTGGCCTG AAGATTGGGG ACGTCAGCTC CTCCGCCGTC 
AAGACGGTGG GCTCTGTCGT CAGCAGCGTG GCACTGACTG GTGTCCTTTC TGGCAACGGT 
GGGACAAATG TGAACATGCC AGTTTCAAAG CCGACCTCGT GGGCTGCCAT TGCCAGCAAG 
CCTGCAAAAC CACAGCCTAA AATGAAAACA AAGAGCGGGC CTGTCATGGG GGGTGGGCTG 
CCCCCTCCAC CCATAAAGCA TAACATGGAC ATTGGCACCT GGGATAACAA GGGGCCTGTG 
CCGAAGGCCC CAGTCCCCCA GCAGGCACCC TCTCCACAGG CTGCCCCACA GCCCCAGCAG 
GTGGCTCAGC CTCTCCCAGC ACAGCCCCCA GCTTTGGCTC AACCGCAGTA TCAGAGCCCT 
CAGCAGCCAC CCCAGACCCG CTGGGTTGCC CCACGCAACA GAAACGCGGC GTTTGGGCAG 
AGCGGAGGGG CTGGCAGCGA TAGCAACTCT CCTGGAAACG TCCAGCCTAA TTCTGCCCCC 
AGCGTCGAAT CCCACCCCGT CCTTGAAAAA CTGAAGGCTG CTCACAGCTA CAACCCGAAA 
GAGTTTGAGT GGAATCTGAA AAGCGGGCGT GTGTTCATCA TCAAGAGCTA CTCTGAGGAC 
GACATCCACC GCTCCATTAA GTACTCCATC TGGTGTAGCA CAGAGCACGG CAACAAGCGC 
CTGGACAGCG CCTTCCGCTG CATGAGCAGC AAGGGGCCCG TCTACCTGCT CTTCAGCGTC 
AATGGGAGTG GGCATTTTTG TGGGGTGGCC GAGATGAAGT CCCCCGTGGA CTACGGCACC 
AGTGCCGGGG TCTGGTCTCA GGACAAGTGG AAGGGGAAGT TTGATGTCCA GTGGATTTTT 
GTTAAGGATG TACCCAATAA CCAGCTCCGG CACATCAGGC TGGAGAATAA CGACAACAAA 
CCGGTCACAA ACTCCCGGGA CACCCAGGAG GTGCCCTTAG AAAAAGCCAA GCAAGTGCTG 
AAAATTATCA GTTCCTACAA GCACACAACC TCCATCTTCG ACGACTTTGC TCACTACGAG 
AAGCGCCAGG AGGAGGAGGA GGTGGTGCGC AAGGAACGGC AGAGTCGAAA CAAACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

YTHDF1 ( XM_024451914.1 ) cDNA ORF clone, Homo sapiens(human) -> XP_024307682.1 Homo sapiens YTH N6-methyladenosine RNA binding protein 1 (YTHDF1), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OHu105123
Clone ID Related Accession (Same CDS sequence)	XM_024451914.1
Accession Version	XM_024451914.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1530bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-05
Organism	Homo sapiens(human)
Product	YTH domain-containing family protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000020.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGAGCGACC CCTACCTGTC CAGCTATTAC CCGCCGTCCA TTGGATTTCC TTACTCCCTC 
AATGAGGCTC CGTGGTCTAC TGCAGGGGAC CCTCCGATTC CATACCTCAC CACCTACGGA 
CAGCTCAGTA ACGGAGACCA TCATTTTATG CACGATGCTG TTTTTGGGCA GCCTGGGGGC 
CTGGGGAACA ACATCTATCA GCACAGGTTC AATTTTTTCC CTGAAAACCC TGCGTTCTCA 
GCATGGGGGA CAAGTGGGTC TCAAGGTCAG CAGACCCAGA GCTCCGCGTA TGGGAGCAGC 
TACACCTACC CCCCGAGCTC CCTGGGTGGC ACGGTGGTTG ATGGGCAGCC AGGCTTTCAC 
AGCGACACCC TCAGCAAGGC CCCCGGGATG AACAGCCTGG AGCAGGGCAT GGTTGGCCTG 
AAGATTGGGG ACGTCAGCTC CTCCGCCGTC AAGACGGTGG GCTCTGTCGT CAGCAGCGTG 
GCACTGACTG GTGTCCTTTC TGGCAACGGT GGGACAAATG TGAACATGCC AGTTTCAAAG 
CCGACCTCGT GGGCTGCCAT TGCCAGCAAG CCTGCAAAAC CACAGCCTAA AATGAAAACA 
AAGAGCGGGC CTGTCATGGG GGGTGGGCTG CCCCCTCCAC CCATAAAGCA TAACATGGAC 
ATTGGCACCT GGGATAACAA GGGGCCTGTG CCGAAGGCCC CAGTCCCCCA GCAGGCACCC 
TCTCCACAGG CTGCCCCACA GCCCCAGCAG GTGGCTCAGC CTCTCCCAGC ACAGCCCCCA 
GCTTTGGCTC AACCGCAGTA TCAGAGCCCT CAGCAGCCAC CCCAGACCCG CTGGGTTGCC 
CCACGCAACA GAAACGCGGC GTTTGGGCAG AGCGGAGGGG CTGGCAGCGA TAGCAACTCT 
CCTGGAAACG TCCAGCCTAA TTCTGCCCCC AGCGTCGAAT CCCACCCCGT CCTTGAAAAA 
CTGAAGGCTG CTCACAGCTA CAACCCGAAA GAGTTTGAGT GGAATCTGAA AAGCGGGCGT 
GTGTTCATCA TCAAGAGCTA CTCTGAGGAC GACATCCACC GCTCCATTAA GTACTCCATC 
TGGTGTAGCA CAGAGCACGG CAACAAGCGC CTGGACAGCG CCTTCCGCTG CATGAGCAGC 
AAGGGGCCCG TCTACCTGCT CTTCAGCGTC AATGGGAGTG GGCATTTTTG TGGGGTGGCC 
GAGATGAAGT CCCCCGTGGA CTACGGCACC AGTGCCGGGG TCTGGTCTCA GGACAAGTGG 
AAGGGGAAGT TTGATGTCCA GTGGATTTTT GTTAAGGATG TACCCAATAA CCAGCTCCGG 
CACATCAGGC TGGAGAATAA CGACAACAAA CCGGTCACAA ACTCCCGGGA CACCCAGGAG 
GTGCCCTTAG AAAAAGCCAA GCAAGTGCTG AAAATTATCA GTTCCTACAA GCACACAACC 
TCCATCTTCG ACGACTTTGC TCACTACGAG AAGCGCCAGG AGGAGGAGGA GGTGGTGCGC 
AAGGAACGGC AGAGTCGAAA CAAACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024307682.1
CDS	208..1737
Translation	MSDPYLSSYYPPSIGFPYSLNEAPWSTAGDPPIPYLTTYGQLSNGDHHFMHDAVFGQPGGLGNNIYQHRFNFFPENPAFSAWGTSGSQGQQTQSSAYGSSYTYPPSSLGGTVVDGQPGFHSDTLSKAPGMNSLEQGMVGLKIGDVSSSAVKTVGSVVSSVALTGVLSGNGGTNVNMPVSKPTSWAAIASKPAKPQPKMKTKSGPVMGGGLPPPPIKHNMDIGTWDNKGPVPKAPVPQQAPSPQAAPQPQQVAQPLPAQPPALAQPQYQSPQQPPQTRWVAPRNRNAAFGQSGGAGSDSNSPGNVQPNSAPSVESHPVLEKLKAAHSYNPKEFEWNLKSGRVFIIKSYSEDDIHRSIKYSIWCSTEHGNKRLDSAFRCMSSKGPVYLLFSVNGSGHFCGVAEMKSPVDYGTSAGVWSQDKWKGKFDVQWIFVKDVPNNQLRHIRLENNDNKPVTNSRDTQEVPLEKAKQVLKIISSYKHTTSIFDDFAHYEKRQEEEEVVRKERQSRNKQ

Target ORF information:

RefSeq Version	XM_024451914.1
Organism	Homo sapiens(human)
Definition	Homo sapiens YTH N6-methyladenosine RNA binding protein 1 (YTHDF1), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024451914.1

ORF Insert Sequence:

ATGAGCGACC CCTACCTGTC CAGCTATTAC CCGCCGTCCA TTGGATTTCC TTACTCCCTC 
AATGAGGCTC CGTGGTCTAC TGCAGGGGAC CCTCCGATTC CATACCTCAC CACCTACGGA 
CAGCTCAGTA ACGGAGACCA TCATTTTATG CACGATGCTG TTTTTGGGCA GCCTGGGGGC 
CTGGGGAACA ACATCTATCA GCACAGGTTC AATTTTTTCC CTGAAAACCC TGCGTTCTCA 
GCATGGGGGA CAAGTGGGTC TCAAGGTCAG CAGACCCAGA GCTCCGCGTA TGGGAGCAGC 
TACACCTACC CCCCGAGCTC CCTGGGTGGC ACGGTGGTTG ATGGGCAGCC AGGCTTTCAC 
AGCGACACCC TCAGCAAGGC CCCCGGGATG AACAGCCTGG AGCAGGGCAT GGTTGGCCTG 
AAGATTGGGG ACGTCAGCTC CTCCGCCGTC AAGACGGTGG GCTCTGTCGT CAGCAGCGTG 
GCACTGACTG GTGTCCTTTC TGGCAACGGT GGGACAAATG TGAACATGCC AGTTTCAAAG 
CCGACCTCGT GGGCTGCCAT TGCCAGCAAG CCTGCAAAAC CACAGCCTAA AATGAAAACA 
AAGAGCGGGC CTGTCATGGG GGGTGGGCTG CCCCCTCCAC CCATAAAGCA TAACATGGAC 
ATTGGCACCT GGGATAACAA GGGGCCTGTG CCGAAGGCCC CAGTCCCCCA GCAGGCACCC 
TCTCCACAGG CTGCCCCACA GCCCCAGCAG GTGGCTCAGC CTCTCCCAGC ACAGCCCCCA 
GCTTTGGCTC AACCGCAGTA TCAGAGCCCT CAGCAGCCAC CCCAGACCCG CTGGGTTGCC 
CCACGCAACA GAAACGCGGC GTTTGGGCAG AGCGGAGGGG CTGGCAGCGA TAGCAACTCT 
CCTGGAAACG TCCAGCCTAA TTCTGCCCCC AGCGTCGAAT CCCACCCCGT CCTTGAAAAA 
CTGAAGGCTG CTCACAGCTA CAACCCGAAA GAGTTTGAGT GGAATCTGAA AAGCGGGCGT 
GTGTTCATCA TCAAGAGCTA CTCTGAGGAC GACATCCACC GCTCCATTAA GTACTCCATC 
TGGTGTAGCA CAGAGCACGG CAACAAGCGC CTGGACAGCG CCTTCCGCTG CATGAGCAGC 
AAGGGGCCCG TCTACCTGCT CTTCAGCGTC AATGGGAGTG GGCATTTTTG TGGGGTGGCC 
GAGATGAAGT CCCCCGTGGA CTACGGCACC AGTGCCGGGG TCTGGTCTCA GGACAAGTGG 
AAGGGGAAGT TTGATGTCCA GTGGATTTTT GTTAAGGATG TACCCAATAA CCAGCTCCGG 
CACATCAGGC TGGAGAATAA CGACAACAAA CCGGTCACAA ACTCCCGGGA CACCCAGGAG 
GTGCCCTTAG AAAAAGCCAA GCAAGTGCTG AAAATTATCA GTTCCTACAA GCACACAACC 
TCCATCTTCG ACGACTTTGC TCACTACGAG AAGCGCCAGG AGGAGGAGGA GGTGGTGCGC 
AAGGAACGGC AGAGTCGAAA CAAACAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

YTHDF3 facilitates translation and decay of N
Cell research27(3)315-328(2017 Mar)
Shi H,Wang X,Lu Z,Zhao BS,Ma H,Hsu PJ,Liu C,He C

Cytoplasmic m
Cell research27(3)444-447(2017 Mar)
Li A,Chen YS,Ping XL,Yang X,Xiao W,Yang Y,Sun HY,Zhu Q,Baidya P,Wang X,Bhattarai DP,Zhao YL,Sun BF,Yang YG

N(6)-methyladenosine of HIV-1 RNA regulates viral infection and HIV-1 Gag protein expression.
eLife5(2016 07)
Tirumuru N,Zhao BS,Lu W,Lu Z,He C,Wu L

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YTHDF1 cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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