RHBDL2 cDNA ORF clone, Homo sapiens(human)

  • Gene

  • Clones

  • gRNAs

The following RHBDL2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RHBDL2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu02567 NM_017821.5
Latest version!
Homo sapiens rhomboid like 2 (RHBDL2), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$154.50-$216.30
$309.00
OHu68806 NM_001304746.2
Latest version!
Homo sapiens rhomboid like 2 (RHBDL2), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
View Old Accession Versions >>
OHu68806 NM_001304746.1 Homo sapiens rhomboid like 2 (RHBDL2), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $223.30
$319.00
OHu02567 NM_017821.4 Homo sapiens rhomboid like 2 (RHBDL2), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector
in pcDNA3.1-C-(k)DYK
$154.50-$216.30
$309.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

  • Reference Sequences (Refseq)
    CloneID OHu02567
    Clone ID Related Accession (Same CDS sequence) NM_017821.4 , NM_017821.5
    Accession Version NM_017821.4 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 912bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2017-10-02
    Organism Homo sapiens(human)
    Product rhomboid-related protein 2 isoform 2
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB036310.1, AK294115.1 and AL139260.19. On Feb 6, 2015 this sequence version replaced NM_017821.3. Transcript Variant: This variant (2) uses an alternate first exon in place of that of variant 1, which results in variant 2 using a downstream translation start site compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.212005.1, SRR1660803.137482.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGCTGCTG TTCATGATCT GGAGATGGAG AGCATGAATC TGAATATGGG GAGAGAGATG 
    AAAGAAGAGC TGGAGGAAGA GGAGAAAATG AGAGAGGATG GGGGAGGTAA AGATCGGGCC
    AAGAGTAAAA AGGTCCACAG GATTGTCTCA AAATGGATGC TGCCCGAAAA GTCCCGAGGA
    ACATACTTGG AGAGAGCTAA CTGCTTCCCG CCTCCCGTGT TCATCATCTC CATCAGCCTG
    GCCGAGCTGG CAGTGTTTAT TTACTATGCT GTGTGGAAGC CTCAGAAACA GTGGATCACG
    TTGGACACAG GCATCTTGGA GAGTCCCTTT ATCTACAGTC CTGAGAAGAG GGAGGAAGCC
    TGGAGGTTTA TCTCATACAT GCTGGTACAT GCTGGAGTTC AGCACATCTT GGGGAATCTT
    TGTATGCAGC TTGTTTTGGG TATTCCCTTG GAAATGGTCC ACAAAGGCCT CCGTGTGGGG
    CTGGTGTACC TGGCAGGAGT GATTGCAGGG TCCCTTGCCA GCTCCATCTT TGACCCACTC
    AGATATCTTG TGGGAGCTTC AGGAGGAGTC TATGCTCTGA TGGGAGGCTA TTTTATGAAT
    GTTCTGGTGA ATTTTCAAGA AATGATTCCT GCCTTTGGAA TTTTCAGACT GCTGATCATC
    ATCCTGATAA TTGTGTTGGA CATGGGATTT GCTCTCTATA GAAGGTTCTT TGTTCCTGAA
    GATGGGTCTC CGGTGTCTTT TGCAGCTCAC ATTGCAGGTG GATTTGCTGG AATGTCCATT
    GGCTACACGG TGTTTAGCTG CTTTGATAAA GCACTGCTGA AAGATCCAAG GTTTTGGATA
    GCAATTGCTG CATATTTAGC TTGTGTCTTA TTTGCTGTGT TTTTCAACAT TTTCCTATCT
    CCAGCAAACT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_060291.2
    CDS275..1186
    Translation

    Target ORF information:

    RefSeq Version NM_017821.4
    Organism Homo sapiens(human)
    Definition Homo sapiens rhomboid like 2 (RHBDL2), transcript variant 2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_017821.4

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGCTGCTG TTCATGATCT GGAGATGGAG AGCATGAATC TGAATATGGG GAGAGAGATG 
    AAAGAAGAGC TGGAGGAAGA GGAGAAAATG AGAGAGGATG GGGGAGGTAA AGATCGGGCC
    AAGAGTAAAA AGGTCCACAG GATTGTCTCA AAATGGATGC TGCCCGAAAA GTCCCGAGGA
    ACATACTTGG AGAGAGCTAA CTGCTTCCCG CCTCCCGTGT TCATCATCTC CATCAGCCTG
    GCCGAGCTGG CAGTGTTTAT TTACTATGCT GTGTGGAAGC CTCAGAAACA GTGGATCACG
    TTGGACACAG GCATCTTGGA GAGTCCCTTT ATCTACAGTC CTGAGAAGAG GGAGGAAGCC
    TGGAGGTTTA TCTCATACAT GCTGGTACAT GCTGGAGTTC AGCACATCTT GGGGAATCTT
    TGTATGCAGC TTGTTTTGGG TATTCCCTTG GAAATGGTCC ACAAAGGCCT CCGTGTGGGG
    CTGGTGTACC TGGCAGGAGT GATTGCAGGG TCCCTTGCCA GCTCCATCTT TGACCCACTC
    AGATATCTTG TGGGAGCTTC AGGAGGAGTC TATGCTCTGA TGGGAGGCTA TTTTATGAAT
    GTTCTGGTGA ATTTTCAAGA AATGATTCCT GCCTTTGGAA TTTTCAGACT GCTGATCATC
    ATCCTGATAA TTGTGTTGGA CATGGGATTT GCTCTCTATA GAAGGTTCTT TGTTCCTGAA
    GATGGGTCTC CGGTGTCTTT TGCAGCTCAC ATTGCAGGTG GATTTGCTGG AATGTCCATT
    GGCTACACGG TGTTTAGCTG CTTTGATAAA GCACTGCTGA AAGATCCAAG GTTTTGGATA
    GCAATTGCTG CATATTTAGC TTGTGTCTTA TTTGCTGTGT TTTTCAACAT TTTCCTATCT
    CCAGCAAACT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu02567
    Clone ID Related Accession (Same CDS sequence) NM_017821.4 , NM_017821.5
    Accession Version NM_017821.5 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 912bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-09-26
    Organism Homo sapiens(human)
    Product rhomboid-related protein 2 isoform 2
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB036310.1, AK294115.1 and AL139260.19. On Nov 23, 2018 this sequence version replaced NM_017821.4. Transcript Variant: This variant (2) uses an alternate first exon in place of that of variant 1, which results in variant 2 using a downstream translation start site compared to variant 1. The resulting isoform (2) is shorter at the N-terminus compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.212005.1, SRR1660803.137482.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2142348 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000372990.6/ ENSP00000362081.1 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGCTGCTG TTCATGATCT GGAGATGGAG AGCATGAATC TGAATATGGG GAGAGAGATG 
    AAAGAAGAGC TGGAGGAAGA GGAGAAAATG AGAGAGGATG GGGGAGGTAA AGATCGGGCC
    AAGAGTAAAA AGGTCCACAG GATTGTCTCA AAATGGATGC TGCCCGAAAA GTCCCGAGGA
    ACATACTTGG AGAGAGCTAA CTGCTTCCCG CCTCCCGTGT TCATCATCTC CATCAGCCTG
    GCCGAGCTGG CAGTGTTTAT TTACTATGCT GTGTGGAAGC CTCAGAAACA GTGGATCACG
    TTGGACACAG GCATCTTGGA GAGTCCCTTT ATCTACAGTC CTGAGAAGAG GGAGGAAGCC
    TGGAGGTTTA TCTCATACAT GCTGGTACAT GCTGGAGTTC AGCACATCTT GGGGAATCTT
    TGTATGCAGC TTGTTTTGGG TATTCCCTTG GAAATGGTCC ACAAAGGCCT CCGTGTGGGG
    CTGGTGTACC TGGCAGGAGT GATTGCAGGG TCCCTTGCCA GCTCCATCTT TGACCCACTC
    AGATATCTTG TGGGAGCTTC AGGAGGAGTC TATGCTCTGA TGGGAGGCTA TTTTATGAAT
    GTTCTGGTGA ATTTTCAAGA AATGATTCCT GCCTTTGGAA TTTTCAGACT GCTGATCATC
    ATCCTGATAA TTGTGTTGGA CATGGGATTT GCTCTCTATA GAAGGTTCTT TGTTCCTGAA
    GATGGGTCTC CGGTGTCTTT TGCAGCTCAC ATTGCAGGTG GATTTGCTGG AATGTCCATT
    GGCTACACGG TGTTTAGCTG CTTTGATAAA GCACTGCTGA AAGATCCAAG GTTTTGGATA
    GCAATTGCTG CATATTTAGC TTGTGTCTTA TTTGCTGTGT TTTTCAACAT TTTCCTATCT
    CCAGCAAACT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_060291.2
    CDS275..1186
    Translation

    Target ORF information:

    RefSeq Version NM_017821.5
    Organism Homo sapiens(human)
    Definition Homo sapiens rhomboid like 2 (RHBDL2), transcript variant 2, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_017821.5

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    ATGGCTGCTG TTCATGATCT GGAGATGGAG AGCATGAATC TGAATATGGG GAGAGAGATG 
    AAAGAAGAGC TGGAGGAAGA GGAGAAAATG AGAGAGGATG GGGGAGGTAA AGATCGGGCC
    AAGAGTAAAA AGGTCCACAG GATTGTCTCA AAATGGATGC TGCCCGAAAA GTCCCGAGGA
    ACATACTTGG AGAGAGCTAA CTGCTTCCCG CCTCCCGTGT TCATCATCTC CATCAGCCTG
    GCCGAGCTGG CAGTGTTTAT TTACTATGCT GTGTGGAAGC CTCAGAAACA GTGGATCACG
    TTGGACACAG GCATCTTGGA GAGTCCCTTT ATCTACAGTC CTGAGAAGAG GGAGGAAGCC
    TGGAGGTTTA TCTCATACAT GCTGGTACAT GCTGGAGTTC AGCACATCTT GGGGAATCTT
    TGTATGCAGC TTGTTTTGGG TATTCCCTTG GAAATGGTCC ACAAAGGCCT CCGTGTGGGG
    CTGGTGTACC TGGCAGGAGT GATTGCAGGG TCCCTTGCCA GCTCCATCTT TGACCCACTC
    AGATATCTTG TGGGAGCTTC AGGAGGAGTC TATGCTCTGA TGGGAGGCTA TTTTATGAAT
    GTTCTGGTGA ATTTTCAAGA AATGATTCCT GCCTTTGGAA TTTTCAGACT GCTGATCATC
    ATCCTGATAA TTGTGTTGGA CATGGGATTT GCTCTCTATA GAAGGTTCTT TGTTCCTGAA
    GATGGGTCTC CGGTGTCTTT TGCAGCTCAC ATTGCAGGTG GATTTGCTGG AATGTCCATT
    GGCTACACGG TGTTTAGCTG CTTTGATAAA GCACTGCTGA AAGATCCAAG GTTTTGGATA
    GCAATTGCTG CATATTTAGC TTGTGTCTTA TTTGCTGTGT TTTTCAACAT TTTCCTATCT
    CCAGCAAACT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu68806
    Clone ID Related Accession (Same CDS sequence) NM_001304746.1 , NM_001304746.2
    Accession Version NM_001304746.1 Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1152bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2018-06-30
    Organism Homo sapiens(human)
    Product rhomboid-related protein 2 isoform 1
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AK294115.1 and AL139260.19. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK294115.1, SRR1803611.13925.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGCAGCTAG GCAAGCGGCA CAAGCTCACA ACTAAAAGTG TCTGCCATGG AAAAGGAGTT 
    GTCATAAGGG TGTTGGCCTT GCCAGGGCCT TCCTGGGTGA GGCGAAGAAG GGAAGGAAAG
    GCCTTGGAAA GCAGTCGTTG CGCCAGACAG CCCAGGGAAG AGCGGCAGCC TGAGGACCTA
    GGGCCACCTG CTGTTCCCTG GGATTCATGT CCTTCTGGGG AGGAGGGAGG ACCCAGGACA
    ATGGCTGCTG TTCATGATCT GGAGATGGAG AGCATGAATC TGAATATGGG GAGAGAGATG
    AAAGAAGAGC TGGAGGAAGA GGAGAAAATG AGAGAGGATG GGGGAGGTAA AGATCGGGCC
    AAGAGTAAAA AGGTCCACAG GATTGTCTCA AAATGGATGC TGCCCGAAAA GTCCCGAGGA
    ACATACTTGG AGAGAGCTAA CTGCTTCCCG CCTCCCGTGT TCATCATCTC CATCAGCCTG
    GCCGAGCTGG CAGTGTTTAT TTACTATGCT GTGTGGAAGC CTCAGAAACA GTGGATCACG
    TTGGACACAG GCATCTTGGA GAGTCCCTTT ATCTACAGTC CTGAGAAGAG GGAGGAAGCC
    TGGAGGTTTA TCTCATACAT GCTGGTACAT GCTGGAGTTC AGCACATCTT GGGGAATCTT
    TGTATGCAGC TTGTTTTGGG TATTCCCTTG GAAATGGTCC ACAAAGGCCT CCGTGTGGGG
    CTGGTGTACC TGGCAGGAGT GATTGCAGGG TCCCTTGCCA GCTCCATCTT TGACCCACTC
    AGATATCTTG TGGGAGCTTC AGGAGGAGTC TATGCTCTGA TGGGAGGCTA TTTTATGAAT
    GTTCTGGTGA ATTTTCAAGA AATGATTCCT GCCTTTGGAA TTTTCAGACT GCTGATCATC
    ATCCTGATAA TTGTGTTGGA CATGGGATTT GCTCTCTATA GAAGGTTCTT TGTTCCTGAA
    GATGGGTCTC CGGTGTCTTT TGCAGCTCAC ATTGCAGGTG GATTTGCTGG AATGTCCATT
    GGCTACACGG TGTTTAGCTG CTTTGATAAA GCACTGCTGA AAGATCCAAG GTTTTGGATA
    GCAATTGCTG CATATTTAGC TTGTGTCTTA TTTGCTGTGT TTTTCAACAT TTTCCTATCT
    CCAGCAAACT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001291675.1
    CDS5..1156
    Translation

    Target ORF information:

    RefSeq Version NM_001304746.1
    Organism Homo sapiens(human)
    Definition Homo sapiens rhomboid like 2 (RHBDL2), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001304746.1

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGCAGCTAG GCAAGCGGCA CAAGCTCACA ACTAAAAGTG TCTGCCATGG AAAAGGAGTT 
    GTCATAAGGG TGTTGGCCTT GCCAGGGCCT TCCTGGGTGA GGCGAAGAAG GGAAGGAAAG
    GCCTTGGAAA GCAGTCGTTG CGCCAGACAG CCCAGGGAAG AGCGGCAGCC TGAGGACCTA
    GGGCCACCTG CTGTTCCCTG GGATTCATGT CCTTCTGGGG AGGAGGGAGG ACCCAGGACA
    ATGGCTGCTG TTCATGATCT GGAGATGGAG AGCATGAATC TGAATATGGG GAGAGAGATG
    AAAGAAGAGC TGGAGGAAGA GGAGAAAATG AGAGAGGATG GGGGAGGTAA AGATCGGGCC
    AAGAGTAAAA AGGTCCACAG GATTGTCTCA AAATGGATGC TGCCCGAAAA GTCCCGAGGA
    ACATACTTGG AGAGAGCTAA CTGCTTCCCG CCTCCCGTGT TCATCATCTC CATCAGCCTG
    GCCGAGCTGG CAGTGTTTAT TTACTATGCT GTGTGGAAGC CTCAGAAACA GTGGATCACG
    TTGGACACAG GCATCTTGGA GAGTCCCTTT ATCTACAGTC CTGAGAAGAG GGAGGAAGCC
    TGGAGGTTTA TCTCATACAT GCTGGTACAT GCTGGAGTTC AGCACATCTT GGGGAATCTT
    TGTATGCAGC TTGTTTTGGG TATTCCCTTG GAAATGGTCC ACAAAGGCCT CCGTGTGGGG
    CTGGTGTACC TGGCAGGAGT GATTGCAGGG TCCCTTGCCA GCTCCATCTT TGACCCACTC
    AGATATCTTG TGGGAGCTTC AGGAGGAGTC TATGCTCTGA TGGGAGGCTA TTTTATGAAT
    GTTCTGGTGA ATTTTCAAGA AATGATTCCT GCCTTTGGAA TTTTCAGACT GCTGATCATC
    ATCCTGATAA TTGTGTTGGA CATGGGATTT GCTCTCTATA GAAGGTTCTT TGTTCCTGAA
    GATGGGTCTC CGGTGTCTTT TGCAGCTCAC ATTGCAGGTG GATTTGCTGG AATGTCCATT
    GGCTACACGG TGTTTAGCTG CTTTGATAAA GCACTGCTGA AAGATCCAAG GTTTTGGATA
    GCAATTGCTG CATATTTAGC TTGTGTCTTA TTTGCTGTGT TTTTCAACAT TTTCCTATCT
    CCAGCAAACT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    CloneID OHu68806
    Clone ID Related Accession (Same CDS sequence) NM_001304746.1 , NM_001304746.2
    Accession Version NM_001304746.2 Latest version! Documents for ORF clone product in default vector
    Sequence Information ORF Nucleotide Sequence (Length: 1152bp)
    Protein sequence
    SNP
    Vector pcDNA3.1-C-(k)DYK or customized vector User Manual
    Clone information Clone Map MSDS
    Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
    ORF Insert Method CloneEZ™ Seamless cloning technology
    Insert Structure linear
    Update Date 2019-09-27
    Organism Homo sapiens(human)
    Product rhomboid-related protein 2 isoform 1
    Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AL139260.19 and AK294115.1. On May 31, 2019 this sequence version replaced NM_001304746.1. Transcript Variant: This variant (1) encodes the longer isoform (1). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.199432.1, SRR1660807.215624.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGCAGCTAG GCAAGCGGCA CAAGCTCACA ACTAAAAGTG TCTGCCATGG AAAAGGAGTT 
    GTCATAAGGG TGTTGGCCTT GCCAGGGCCT TCCTGGGTGA GGCGAAGAAG GGAAGGAAAG
    GCCTTGGAAA GCAGTCGTTG CGCCAGACAG CCCAGGGAAG AGCGGCAGCC TGAGGACCTA
    GGGCCACCTG CTGTTCCCTG GGATTCATGT CCTTCTGGGG AGGAGGGAGG ACCCAGGACA
    ATGGCTGCTG TTCATGATCT GGAGATGGAG AGCATGAATC TGAATATGGG GAGAGAGATG
    AAAGAAGAGC TGGAGGAAGA GGAGAAAATG AGAGAGGATG GGGGAGGTAA AGATCGGGCC
    AAGAGTAAAA AGGTCCACAG GATTGTCTCA AAATGGATGC TGCCCGAAAA GTCCCGAGGA
    ACATACTTGG AGAGAGCTAA CTGCTTCCCG CCTCCCGTGT TCATCATCTC CATCAGCCTG
    GCCGAGCTGG CAGTGTTTAT TTACTATGCT GTGTGGAAGC CTCAGAAACA GTGGATCACG
    TTGGACACAG GCATCTTGGA GAGTCCCTTT ATCTACAGTC CTGAGAAGAG GGAGGAAGCC
    TGGAGGTTTA TCTCATACAT GCTGGTACAT GCTGGAGTTC AGCACATCTT GGGGAATCTT
    TGTATGCAGC TTGTTTTGGG TATTCCCTTG GAAATGGTCC ACAAAGGCCT CCGTGTGGGG
    CTGGTGTACC TGGCAGGAGT GATTGCAGGG TCCCTTGCCA GCTCCATCTT TGACCCACTC
    AGATATCTTG TGGGAGCTTC AGGAGGAGTC TATGCTCTGA TGGGAGGCTA TTTTATGAAT
    GTTCTGGTGA ATTTTCAAGA AATGATTCCT GCCTTTGGAA TTTTCAGACT GCTGATCATC
    ATCCTGATAA TTGTGTTGGA CATGGGATTT GCTCTCTATA GAAGGTTCTT TGTTCCTGAA
    GATGGGTCTC CGGTGTCTTT TGCAGCTCAC ATTGCAGGTG GATTTGCTGG AATGTCCATT
    GGCTACACGG TGTTTAGCTG CTTTGATAAA GCACTGCTGA AAGATCCAAG GTTTTGGATA
    GCAATTGCTG CATATTTAGC TTGTGTCTTA TTTGCTGTGT TTTTCAACAT TTTCCTATCT
    CCAGCAAACT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

    RefSeq NP_001291675.1
    CDS11..1162
    Translation

    Target ORF information:

    RefSeq Version NM_001304746.2
    Organism Homo sapiens(human)
    Definition Homo sapiens rhomboid like 2 (RHBDL2), transcript variant 1, mRNA.

    Target ORF information:

    Epitope DYKDDDDK
    Bacterial selection AMPR
    Mammalian selection NeoR
    Vector pcDNA3.1+/C-(K)DYK
    NM_001304746.2

    ORF Insert Sequence:

    1
    61
    121
    181
    241
    301
    361
    421
    481
    541
    601
    661
    721
    781
    841
    901
    961
    1021
    1081
    1141
    ATGCAGCTAG GCAAGCGGCA CAAGCTCACA ACTAAAAGTG TCTGCCATGG AAAAGGAGTT 
    GTCATAAGGG TGTTGGCCTT GCCAGGGCCT TCCTGGGTGA GGCGAAGAAG GGAAGGAAAG
    GCCTTGGAAA GCAGTCGTTG CGCCAGACAG CCCAGGGAAG AGCGGCAGCC TGAGGACCTA
    GGGCCACCTG CTGTTCCCTG GGATTCATGT CCTTCTGGGG AGGAGGGAGG ACCCAGGACA
    ATGGCTGCTG TTCATGATCT GGAGATGGAG AGCATGAATC TGAATATGGG GAGAGAGATG
    AAAGAAGAGC TGGAGGAAGA GGAGAAAATG AGAGAGGATG GGGGAGGTAA AGATCGGGCC
    AAGAGTAAAA AGGTCCACAG GATTGTCTCA AAATGGATGC TGCCCGAAAA GTCCCGAGGA
    ACATACTTGG AGAGAGCTAA CTGCTTCCCG CCTCCCGTGT TCATCATCTC CATCAGCCTG
    GCCGAGCTGG CAGTGTTTAT TTACTATGCT GTGTGGAAGC CTCAGAAACA GTGGATCACG
    TTGGACACAG GCATCTTGGA GAGTCCCTTT ATCTACAGTC CTGAGAAGAG GGAGGAAGCC
    TGGAGGTTTA TCTCATACAT GCTGGTACAT GCTGGAGTTC AGCACATCTT GGGGAATCTT
    TGTATGCAGC TTGTTTTGGG TATTCCCTTG GAAATGGTCC ACAAAGGCCT CCGTGTGGGG
    CTGGTGTACC TGGCAGGAGT GATTGCAGGG TCCCTTGCCA GCTCCATCTT TGACCCACTC
    AGATATCTTG TGGGAGCTTC AGGAGGAGTC TATGCTCTGA TGGGAGGCTA TTTTATGAAT
    GTTCTGGTGA ATTTTCAAGA AATGATTCCT GCCTTTGGAA TTTTCAGACT GCTGATCATC
    ATCCTGATAA TTGTGTTGGA CATGGGATTT GCTCTCTATA GAAGGTTCTT TGTTCCTGAA
    GATGGGTCTC CGGTGTCTTT TGCAGCTCAC ATTGCAGGTG GATTTGCTGG AATGTCCATT
    GGCTACACGG TGTTTAGCTG CTTTGATAAA GCACTGCTGA AAGATCCAAG GTTTTGGATA
    GCAATTGCTG CATATTTAGC TTGTGTCTTA TTTGCTGTGT TTTTCAACAT TTTCCTATCT
    CCAGCAAACT GA

    The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

  • PubMed

    The rhomboid-like superfamily: molecular mechanisms and biological roles.
    Annual review of cell and developmental biology30235-54(2014)
    Freeman M


    Emerging role of rhomboid family proteins in mammalian biology and disease.
    Biochimica et biophysica acta1828(12)2840-8(2013 Dec)
    Bergbold N,Lemberg MK


    Sampling the membrane: function of rhomboid-family proteins.
    Trends in cell biology23(5)210-7(2013 May)
    Lemberg MK


    Meta-analyses identify 13 loci associated with age at menopause and highlight DNA repair and immune pathways.
    Nature genetics44(3)260-8(2012 Jan)
    Stolk L,Perry JR,Chasman DI,He C,Mangino M,Sulem P,Barbalic M,Broer L,Byrne EM,Ernst F,Esko T,Franceschini N,Gudbjartsson DF,Hottenga JJ,Kraft P,McArdle PF,Porcu E,Shin SY,Smith AV,van Wingerden S,Zhai G,Zhuang WV,Albrecht E,Alizadeh BZ,Aspelund T,Bandinelli S,Lauc LB,Beckmann JS,Boban M,Boerwinkle E,Broekmans FJ,Burri A,Campbell H,Chanock SJ,Chen C,Cornelis MC,Corre T,Coviello AD,d'Adamo P,Davies G,de Faire U,de Geus EJ,Deary IJ,Dedoussis GV,Deloukas P,Ebrahim S,Eiriksdottir G,Emilsson V,Eriksson JG,Fauser BC,Ferreli L,Ferrucci L,Fischer K,Folsom AR,Garcia ME,Gasparini P,Gieger C,Glazer N,Grobbee DE,Hall P,Haller T,Hankinson SE,Hass M,Hayward C,Heath AC,Hofman A,Ingelsson E,Janssens AC,Johnson AD,Karasik D,Kardia SL,Keyzer J,Kiel DP,Kolcic I,Kutalik Z,Lahti J,Lai S,Laisk T,Laven JS,Lawlor DA,Liu J,Lopez LM,Louwers YV,Magnusson PK,Marongiu M,Martin NG,Klaric IM,Masciullo C,McKnight B,Medland SE,Melzer D,Mooser V,Navarro P,Newman AB,Nyholt DR,Onland-Moret NC,Palotie A,Par? G,Parker AN,Pedersen NL,Peeters PH,Pistis G,Plump AS,Polasek O,Pop VJ,Psaty BM,R?ikk?nen K,Rehnberg E,Rotter JI,Rudan I,Sala C,Salumets A,Scuteri A,Singleton A,Smith JA,Snieder H,Soranzo N,Stacey SN,Starr JM,Stathopoulou MG,Stirrups K,Stolk RP,Styrkarsdottir U,Sun YV,Tenesa A,Thorand B,Toniolo D,Tryggvadottir L,Tsui K,Ulivi S,van Dam RM,van der Schouw YT,van Gils CH,van Nierop P,Vink JM,Visscher PM,Voorhuis M,Waeber G,Wallaschofski H,Wichmann HE,Widen E,Wijnands-van Gent CJ,Willemsen G,Wilson JF,Wolffenbuttel BH,Wright AF,Yerges-Armstrong LM,Zemunik T,Zgaga L,Zillikens MC,Zygmunt M,,Arnold AM,Boomsma DI,Buring JE,Crisponi L,Demerath EW,Gudnason V,Harris TB,Hu FB,Hunter DJ,Launer LJ,Metspalu A,Montgomery GW,Oostra BA,Ridker PM,Sanna S,Schlessinger D,Spector TD,Stefansson K,Streeten EA,Thorsteinsdottir U,Uda M,Uitterlinden AG,van Duijn CM,V?lzke H,Murray A,Murabito JM,Visser JA,Lunetta KL


    The rhomboid protease family: a decade of progress on function and mechanism.
    Genome biology12(10)231(2011 Oct)
    Urban S,Dickey SW


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