Gene Symbol | XKR8 |
Entrez Gene ID | 55113 |
Full Name | XK related 8 |
Synonyms | XRG8,hXkr8 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
ORF » Species Summary » Homo sapiens » XKR8 cDNA ORF clone
Gene Symbol | XKR8 |
Entrez Gene ID | 55113 |
Full Name | XK related 8 |
Synonyms | XRG8,hXkr8 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_018053.3 | NP_060523.2 | XK-related protein 8 |
XM_011541680.2 | XP_011539982.1 | XK-related protein 8 isoform X2 |
NM_018053.4 | NP_060523.2 | XK-related protein 8 |
XM_011541680.3 | XP_011539982.1 | XK-related protein 8 isoform X2 |
XM_011541679.3 | XP_011539981.1 | XK-related protein 8 isoform X1 |
XM_011541679.2 | XP_011539981.1 | XK-related protein 8 isoform X1 |
Pan troglodytes (chimpanzee) | XKR8 | NP_001028209.1 |
Canis lupus familiaris (dog) | XKR8 | XP_003638966.1 |
Danio rerio (zebrafish) | xkr8.3 | NP_001006014.2 |
Homo sapiens (human) | XKR8 | NP_060523.2 |
Bos taurus (cattle) | XKR8 | XP_002685733.1 |
Rattus norvegicus (Norway rat) | Xkr8 | NP_001012099.1 |
Gallus gallus (chicken) | XKR8 | NP_001038158.1 |
Mus musculus (house mouse) | Xkr8 | NP_958756.1 |
Xenopus tropicalis (tropical clawed frog) | xkr8 | NP_001029116.1 |
Xk-related protein 8 regulates myoblast differentiation and survival.
Kim GW, Nam GH, Kim IS, Park SY
The FEBS journal284(21)3575-3588(2017 Nov)
Xkr8 phospholipid scrambling complex in apoptotic phosphatidylserine exposure.
Suzuki J, Imanishi E, Nagata S
Proceedings of the National Academy of Sciences of the United States of America113(34)9509-14(2016 08)
Getting to the Outer Leaflet: Physiology of Phosphatidylserine Exposure at the Plasma Membrane.
Bevers EM, Williamson PL
Physiological reviews96(2)605-45(2016 Apr)
Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells.
Suzuki J, Denning DP, Imanishi E, Horvitz HR, Nagata S
Science (New York, N.Y.)341(6144)403-6(2013 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The Xkr8 influences myogenesis by acting as a positive regulator of terminal differentiation and myoblast survival.
Title: Xk-related protein 8 regulates myoblast differentiation and survival.
facilitates transbilayer migration of lipids [review]
Title: Getting to the Outer Leaflet: Physiology of Phosphatidylserine Exposure at the Plasma Membrane.
findings show the Xk-family protein Xkr8 mediates phosphatidylserine exposure in response to apoptotic stimuli; Xk-family proteins have evolutionarily conserved roles in promoting phagocytosis of dying cells by altering the phospholipid distribution in the plasma membrane
Title: Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells.
The following XKR8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the XKR8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu29598 | |
Clone ID Related Accession (Same CDS sequence) | NM_018053.3 , NM_018053.4 | |
Accession Version | NM_018053.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1188bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-03 | |
Organism | Homo sapiens(human) | |
Product | XK-related protein 8 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK091615.1, BC013379.2 and AL512288.19. On Feb 1, 2015 this sequence version replaced NM_018053.2. ##Evidence-Data-START## Transcript exon combination :: AK091615.1, SRR1660809.129701.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCCCTGGT CGTCCCGCGG CGCCCTCCTT CGGGACCTGG TCCTGGGCGT GCTGGGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_060523.2 |
CDS | 609..1796 |
Translation |
Target ORF information:
Target ORF information:
|
NM_018053.3 |
1 | ATGCCCTGGT CGTCCCGCGG CGCCCTCCTT CGGGACCTGG TCCTGGGCGT GCTGGGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu29598 | |
Clone ID Related Accession (Same CDS sequence) | NM_018053.3 , NM_018053.4 | |
Accession Version | NM_018053.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1188bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-14 | |
Organism | Homo sapiens(human) | |
Product | XK-related protein 8 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL512288.19. On Jul 29, 2019 this sequence version replaced NM_018053.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK091615.1, AK026024.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCCCTGGT CGTCCCGCGG CGCCCTCCTT CGGGACCTGG TCCTGGGCGT GCTGGGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_060523.2 |
CDS | 98..1285 |
Translation |
Target ORF information:
Target ORF information:
|
NM_018053.4 |
1 | ATGCCCTGGT CGTCCCGCGG CGCCCTCCTT CGGGACCTGG TCCTGGGCGT GCTGGGCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu68998 | |
Clone ID Related Accession (Same CDS sequence) | XM_011541679.3 , XM_011541679.2 | |
Accession Version | XM_011541679.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1350bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | XK-related protein 8 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011541679.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCTCGG CGGCCGCTAC CTGTGGGCGG CGCTGGTGCT GGCGCTGCTG GGCCTGGCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011539981.1 |
CDS | 245..1594 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011541679.3 |
1 | ATGCGCTCGG CGGCCGCTAC CTGTGGGCGG CGCTGGTGCT GGCGCTGCTG GGCCTGGCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu68998 | |
Clone ID Related Accession (Same CDS sequence) | XM_011541679.3 , XM_011541679.2 | |
Accession Version | XM_011541679.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1350bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | XK-related protein 8 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011541679.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCTCGG CGGCCGCTAC CTGTGGGCGG CGCTGGTGCT GGCGCTGCTG GGCCTGGCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011539981.1 |
CDS | 718..2067 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011541679.2 |
1 | ATGCGCTCGG CGGCCGCTAC CTGTGGGCGG CGCTGGTGCT GGCGCTGCTG GGCCTGGCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu68999 | |
Clone ID Related Accession (Same CDS sequence) | XM_011541680.2 , XM_011541680.3 | |
Accession Version | XM_011541680.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1242bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | XK-related protein 8 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011541680.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCTCGG CGGCCGCTAC CTGTGGGCGG CGCTGGTGCT GGCGCTGCTG GGCCTGGCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011539982.1 |
CDS | 718..1959 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011541680.2 |
1 | ATGCGCTCGG CGGCCGCTAC CTGTGGGCGG CGCTGGTGCT GGCGCTGCTG GGCCTGGCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu68999 | |
Clone ID Related Accession (Same CDS sequence) | XM_011541680.2 , XM_011541680.3 | |
Accession Version | XM_011541680.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1242bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | XK-related protein 8 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_011541680.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGCTCGG CGGCCGCTAC CTGTGGGCGG CGCTGGTGCT GGCGCTGCTG GGCCTGGCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011539982.1 |
CDS | 245..1486 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011541680.3 |
1 | ATGCGCTCGG CGGCCGCTAC CTGTGGGCGG CGCTGGTGCT GGCGCTGCTG GGCCTGGCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Xk-related protein 8 regulates myoblast differentiation and survival. |
Xkr8 phospholipid scrambling complex in apoptotic phosphatidylserine exposure. |
Getting to the Outer Leaflet: Physiology of Phosphatidylserine Exposure at the Plasma Membrane. |
Xk-related protein 8 and CED-8 promote phosphatidylserine exposure in apoptotic cells. |