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ELMOD1 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol ELMOD1
Entrez Gene ID 55531
Full Name ELMO domain containing 1
General protein information
Preferred Names

ELMO domain containing 1

Names

ELMO domain-containing protein 1
ELMO/CED-12 domain containing 1
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

11

11q22.3
Disorder MIM:

615456


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_017017994.1 XP_016873483.1 ELMO domain-containing protein 1 isoform X1
XM_017017995.1 XP_016873484.1 ELMO domain-containing protein 1 isoform X1
XM_017017994.2 XP_016873483.1 ELMO domain-containing protein 1 isoform X1
XM_017017995.2 XP_016873484.1 ELMO domain-containing protein 1 isoform X1
NM_001308018.1 NP_001294947.1 ELMO domain-containing protein 1 isoform 3
NM_001130037.1 NP_001123509.1 ELMO domain-containing protein 1 isoform 2
NM_018712.4 NP_061182.3 ELMO domain-containing protein 1 isoform 1
NM_018712.3 NP_061182.3 ELMO domain-containing protein 1 isoform 1

Pathways from BioSystems


Homologies


Homo sapiens (human) ELMOD1 NP_061182.3
Bos taurus (cattle) ELMOD1 NP_001071576.1
Pan troglodytes (chimpanzee) ELMOD1 XP_003313399.2
ELMOD1 XP_001103189.1
Rattus norvegicus (Norway rat) Elmod1 NP_001178508.1
Gallus gallus (chicken) ELMOD1 XP_417165.1
Danio rerio (zebrafish) elmod1 NP_001074150.1
Xenopus tropicalis (tropical clawed frog) elmod1 NP_001072315.1
Canis lupus familiaris (dog) ELMOD1 XP_005619892.1
Mus musculus (house mouse) Elmod1 NP_808437.2

Gene Ontology


Bibliography

Related articles in PubMed

ELMOD1 stimulates ARF6-GTP hydrolysis to stabilize apical structures in developing vestibular hair cells.
Krey JF, Dumont RA, Wilmarth PA, David LL, Johnson KR, Barr-Gillespie PG
The Journal of neuroscience : the official journal of the Society for Neuroscience(2017 Dec)

Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock.
Hern?ndez-V?squez MN, Adame-Garc?a SR, Hamoud N, Chidiac R, Reyes-Cruz G, Gratton JP, C?t? JF, V?zquez-Prado J
The Journal of biological chemistry292(29)12178-12191(2017 07)

Characterization of recombinant ELMOD (cell engulfment and motility domain) proteins as GTPase-activating proteins (GAPs) for ARF family GTPases.
Ivanova AA, East MP, Yi SL, Kahn RA
The Journal of biological chemistry289(16)11111-21(2014 Apr)

High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Hasson SA, Kane LA, Yamano K, Huang CH, Sliter DA, Buehler E, Wang C, Heman-Ackah SM, Hessa T, Guha R, Martin SE, Youle RJ
Nature504(7479)291-5(2013 Dec)

An approach based on a genome-wide association study reveals candidate loci for narcolepsy.
Shimada M, Miyagawa T, Kawashima M, Tanaka S, Honda Y, Honda M, Tokunaga K
Human genetics128(4)433-41(2010 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data suggest that GPR124 promotes cell adhesion via interaction with Elmo1-Dock180 and intersectin 1/2; this constitutes a previously unrecognized heteromeric complex that is putatively involved in GPR124-dependent adhesive/angiogenic responses in vascular endothelial cells. (GPR124 = G-protein coupled receptor 124; Elmo1 = ELMO domain-containing protein 1; Dock180 = dedicator of cytokinesis protein 1 180 kDa)
Title: Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock.

The non-opioid sigma-1 receptor (S1R) was identified as a novel effector of GAP activity of ELMOD1-3 proteins as its direct binding to either ELMOD1 or ELMOD2 resulted in loss of GAP activity.
Title: Characterization of recombinant ELMOD (cell engulfment and motility domain) proteins as GTPase-activating proteins (GAPs) for ARF family GTPases.

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: An approach based on a genome-wide association study reveals candidate loci for narcolepsy.

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

The following ELMOD1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ELMOD1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu02840 NM_018712.4
Latest version!		 Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $189.50-$265.30
$379.00
OHu69436 NM_001308018.1
Latest version!		 Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $139.30
$199.00
OHu31807 NM_001130037.1
Latest version!		 Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $216.30
$309.00
OHu92361 XM_017017995.2
Latest version!		 Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $139.30
$199.00
OHu92361 XM_017017994.2
Latest version!		 Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $139.30
$199.00
View Old Accession Versions >>
OHu92361 XM_017017994.1 Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $139.30
$199.00
OHu92361 XM_017017995.1 Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $139.30
$199.00
OHu02840 NM_018712.3 Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $189.50-$265.30
$379.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu02840
Clone ID Related Accession (Same CDS sequence) NM_018712.4 , NM_018712.3
Accession Version NM_018712.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1005bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-05-01
Organism Homo sapiens(human)
Product ELMO domain-containing protein 1 isoform 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC375486.1, BC028725.2 and AP002353.4. On Nov 23, 2018 this sequence version replaced NM_018712.3. Transcript Variant: This variant (1) represents the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC028725.2, SRR1803612.70661.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2146411 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000265840.12/ ENSP00000265840.7 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAAGCACT TCCTGAGAAT GTTGATCCAG GTATGCCTGT ATTTTTACTG TAAATTTCTG 
TGGCGCTGCC TGAAATTTGT AATGAGGAAG CTAACTGGAA GATGTGAACT ACAACGGATC 
TGTTATAATA CCAAGCCGGG AGCTTCTAGA ACCATGAAAA TCGAAACATC ACTGAGGGAT 
TCTAAAAGTA AGCTGTTGCA GACTTCTGTG AGTGTTCACC CCGACGCTAT TGAAAAAACT 
ATAGAAGATA TCATGGAACT GAAAAAAATT AATCCTGACG TAAATCCACA GCTGGGAATC 
TCTCTTCAGG CTTGCCTTCT GCAAATCGTT GGGTACAGGA ACCTTATTGC AGATGTGGAA 
AAACTGCGTA GAGAGGCCTA TGATTCTGAT AATCCCCAAC ATGAAGAAAT GCTTTTGAAG 
TTATGGAAAT TCTTGAAGCC CAATACTCCA CTGGAATCTC GGATTTCTAA GCAGTGGTGT 
GAAATTGGTT TCCAAGGTGA TGATCCTAAA ACAGACTTTC GAGGAATGGG ACTTCTGGGA 
CTGTACAATT TGCAGTATTT CGCGGAAAGG GATGCCACAG CAGCTCAGCA GGTCCTGTCT 
GACTCTCTTC ATCCGAAATG CAGGGATATC ACTAAAGAAG AAATAAGCAA ATTCAGCAAA 
GCAGAATGGG AGAAGAAAAG GATGGATAAG GCAATTGGGT ACTCATTTGC AATTGTGGGC 
ATCAATATAA CTGACCTGGC ATATAATCTA CTGGTCAGCG GAGCTCTAAA AACCCATTTC 
TACAATATCG CCCCAGAAGC TCCAACATTG TCTCACTTTC AGCAAACATT CTGCTATTTG 
ATGCATGAAT TTCATAAGTT TTGGATCGAA GAGGACCCCA TGGACATAAT GGAATTTAAT 
CGTGTGAGGG AGAAATTCCG CAAGAGGATC ATCAAACAGC TGCAGAACCC AGACATGGCG 
CTGTGCCCAC ATTTTGCTGC CTCGGAAGGT TTAATCAACA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_061182.3
CDS349..1353
Translation

Target ORF information:

RefSeq Version NM_018712.4
Organism Homo sapiens(human)
Definition Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_018712.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAAGCACT TCCTGAGAAT GTTGATCCAG GTATGCCTGT ATTTTTACTG TAAATTTCTG 
TGGCGCTGCC TGAAATTTGT AATGAGGAAG CTAACTGGAA GATGTGAACT ACAACGGATC 
TGTTATAATA CCAAGCCGGG AGCTTCTAGA ACCATGAAAA TCGAAACATC ACTGAGGGAT 
TCTAAAAGTA AGCTGTTGCA GACTTCTGTG AGTGTTCACC CCGACGCTAT TGAAAAAACT 
ATAGAAGATA TCATGGAACT GAAAAAAATT AATCCTGACG TAAATCCACA GCTGGGAATC 
TCTCTTCAGG CTTGCCTTCT GCAAATCGTT GGGTACAGGA ACCTTATTGC AGATGTGGAA 
AAACTGCGTA GAGAGGCCTA TGATTCTGAT AATCCCCAAC ATGAAGAAAT GCTTTTGAAG 
TTATGGAAAT TCTTGAAGCC CAATACTCCA CTGGAATCTC GGATTTCTAA GCAGTGGTGT 
GAAATTGGTT TCCAAGGTGA TGATCCTAAA ACAGACTTTC GAGGAATGGG ACTTCTGGGA 
CTGTACAATT TGCAGTATTT CGCGGAAAGG GATGCCACAG CAGCTCAGCA GGTCCTGTCT 
GACTCTCTTC ATCCGAAATG CAGGGATATC ACTAAAGAAG AAATAAGCAA ATTCAGCAAA 
GCAGAATGGG AGAAGAAAAG GATGGATAAG GCAATTGGGT ACTCATTTGC AATTGTGGGC 
ATCAATATAA CTGACCTGGC ATATAATCTA CTGGTCAGCG GAGCTCTAAA AACCCATTTC 
TACAATATCG CCCCAGAAGC TCCAACATTG TCTCACTTTC AGCAAACATT CTGCTATTTG 
ATGCATGAAT TTCATAAGTT TTGGATCGAA GAGGACCCCA TGGACATAAT GGAATTTAAT 
CGTGTGAGGG AGAAATTCCG CAAGAGGATC ATCAAACAGC TGCAGAACCC AGACATGGCG 
CTGTGCCCAC ATTTTGCTGC CTCGGAAGGT TTAATCAACA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu02840
Clone ID Related Accession (Same CDS sequence) NM_018712.4 , NM_018712.3
Accession Version NM_018712.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1005bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-01
Organism Homo sapiens(human)
Product ELMO domain-containing protein 1 isoform 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DC375486.1, BC028725.2 and AP002353.4. On Jul 11, 2008 this sequence version replaced NM_018712.2. Transcript Variant: This variant (1) represents the longest isoform (1). ##Evidence-Data-START## Transcript exon combination :: BC028725.2, SRR1803612.70661.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2146411 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAAGCACT TCCTGAGAAT GTTGATCCAG GTATGCCTGT ATTTTTACTG TAAATTTCTG 
TGGCGCTGCC TGAAATTTGT AATGAGGAAG CTAACTGGAA GATGTGAACT ACAACGGATC 
TGTTATAATA CCAAGCCGGG AGCTTCTAGA ACCATGAAAA TCGAAACATC ACTGAGGGAT 
TCTAAAAGTA AGCTGTTGCA GACTTCTGTG AGTGTTCACC CCGACGCTAT TGAAAAAACT 
ATAGAAGATA TCATGGAACT GAAAAAAATT AATCCTGACG TAAATCCACA GCTGGGAATC 
TCTCTTCAGG CTTGCCTTCT GCAAATCGTT GGGTACAGGA ACCTTATTGC AGATGTGGAA 
AAACTGCGTA GAGAGGCCTA TGATTCTGAT AATCCCCAAC ATGAAGAAAT GCTTTTGAAG 
TTATGGAAAT TCTTGAAGCC CAATACTCCA CTGGAATCTC GGATTTCTAA GCAGTGGTGT 
GAAATTGGTT TCCAAGGTGA TGATCCTAAA ACAGACTTTC GAGGAATGGG ACTTCTGGGA 
CTGTACAATT TGCAGTATTT CGCGGAAAGG GATGCCACAG CAGCTCAGCA GGTCCTGTCT 
GACTCTCTTC ATCCGAAATG CAGGGATATC ACTAAAGAAG AAATAAGCAA ATTCAGCAAA 
GCAGAATGGG AGAAGAAAAG GATGGATAAG GCAATTGGGT ACTCATTTGC AATTGTGGGC 
ATCAATATAA CTGACCTGGC ATATAATCTA CTGGTCAGCG GAGCTCTAAA AACCCATTTC 
TACAATATCG CCCCAGAAGC TCCAACATTG TCTCACTTTC AGCAAACATT CTGCTATTTG 
ATGCATGAAT TTCATAAGTT TTGGATCGAA GAGGACCCCA TGGACATAAT GGAATTTAAT 
CGTGTGAGGG AGAAATTCCG CAAGAGGATC ATCAAACAGC TGCAGAACCC AGACATGGCG 
CTGTGCCCAC ATTTTGCTGC CTCGGAAGGT TTAATCAACA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_061182.3
CDS405..1409
Translation

Target ORF information:

RefSeq Version NM_018712.3
Organism Homo sapiens(human)
Definition Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_018712.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAAGCACT TCCTGAGAAT GTTGATCCAG GTATGCCTGT ATTTTTACTG TAAATTTCTG 
TGGCGCTGCC TGAAATTTGT AATGAGGAAG CTAACTGGAA GATGTGAACT ACAACGGATC 
TGTTATAATA CCAAGCCGGG AGCTTCTAGA ACCATGAAAA TCGAAACATC ACTGAGGGAT 
TCTAAAAGTA AGCTGTTGCA GACTTCTGTG AGTGTTCACC CCGACGCTAT TGAAAAAACT 
ATAGAAGATA TCATGGAACT GAAAAAAATT AATCCTGACG TAAATCCACA GCTGGGAATC 
TCTCTTCAGG CTTGCCTTCT GCAAATCGTT GGGTACAGGA ACCTTATTGC AGATGTGGAA 
AAACTGCGTA GAGAGGCCTA TGATTCTGAT AATCCCCAAC ATGAAGAAAT GCTTTTGAAG 
TTATGGAAAT TCTTGAAGCC CAATACTCCA CTGGAATCTC GGATTTCTAA GCAGTGGTGT 
GAAATTGGTT TCCAAGGTGA TGATCCTAAA ACAGACTTTC GAGGAATGGG ACTTCTGGGA 
CTGTACAATT TGCAGTATTT CGCGGAAAGG GATGCCACAG CAGCTCAGCA GGTCCTGTCT 
GACTCTCTTC ATCCGAAATG CAGGGATATC ACTAAAGAAG AAATAAGCAA ATTCAGCAAA 
GCAGAATGGG AGAAGAAAAG GATGGATAAG GCAATTGGGT ACTCATTTGC AATTGTGGGC 
ATCAATATAA CTGACCTGGC ATATAATCTA CTGGTCAGCG GAGCTCTAAA AACCCATTTC 
TACAATATCG CCCCAGAAGC TCCAACATTG TCTCACTTTC AGCAAACATT CTGCTATTTG 
ATGCATGAAT TTCATAAGTT TTGGATCGAA GAGGACCCCA TGGACATAAT GGAATTTAAT 
CGTGTGAGGG AGAAATTCCG CAAGAGGATC ATCAAACAGC TGCAGAACCC AGACATGGCG 
CTGTGCCCAC ATTTTGCTGC CTCGGAAGGT TTAATCAACA TGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu69436
Clone ID Related Accession (Same CDS sequence) NM_001308018.1
Accession Version NM_001308018.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 987bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-05
Organism Homo sapiens(human)
Product ELMO domain-containing protein 1 isoform 3
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK297351.1, AK303689.1, AL359601.1, AP002353.4 and AA450353.1. On Apr 21, 2015 this sequence version replaced XM_011542894.1. Transcript Variant: This variant (3) differs in the 5' UTR and uses an alternate exon in the 5' coding region that results in use of a downstream start codon compared to variant 1. It encodes isoform 3, which has a shorter N-terminus compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: AK297351.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2147596, SAMEA2148874 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTTGATCC AGGTATGCCT GTATTTTTAC TGTAAATTTC TGTGGCGCTG CCTGAAATTT 
GTAATGAGGA AGCTAACTGG AAGATGTGAA CTACAACGGA TCTGTTATAA TACCAAGCCG 
GGAGCTTCTA GAACCATGAA AATCGAAACA TCACTGAGGG ATTCTAAAAG TAAGCTGTTG 
CAGACTTCTG TGAGTGTTCA CCCCGACGCT ATTGAAAAAA CTATAGAAGA TATCATGGAA 
CTGAAAAAAA TTAATCCTGA CGTAAATCCA CAGCTGGGAA TCTCTCTTCA GGCTTGCCTT 
CTGCAAATCG TTGGGTACAG GAACCTTATT GCAGATGTGG AAAAACTGCG TAGAGAGGCC 
TATGATTCTG ATAATCCCCA ACATGAAGAA ATGCTTTTGA AGTTATGGAA ATTCTTGAAG 
CCCAATACTC CACTGGAATC TCGGATTTCT AAGCAGTGGT GTGAAATTGG TTTCCAAGGT 
GATGATCCTA AAACAGACTT TCGAGGAATG GGACTTCTGG GACTGTACAA TTTGCAGTAT 
TTCGCGGAAA GGGATGCCAC AGCAGCTCAG CAGGTCCTGT CTGACTCTCT TCATCCGAAA 
TGCAGGGATA TCACTAAAGA AGAAATAAGC AAATTCAGCA AAGCAGAATG GGAGAAGAAA 
AGGATGGATA AGGCAATTGG GTACTCATTT GCAATTGTGG GCATCAATAT AACTGACCTG 
GCATATAATC TACTGGTCAG CGGAGCTCTA AAAACCCATT TCTACAATAT CGCCCCAGAA 
GCTCCAACAT TGTCTCACTT TCAGCAAACA TTCTGCTATT TGATGCATGA ATTTCATAAG 
TTTTGGATCG AAGAGGACCC CATGGACATA ATGGAATTTA ATCGTGTGAG GGAGAAATTC 
CGCAAGAGGA TCATCAAACA GCTGCAGAAC CCAGACATGG CGCTGTGCCC ACATTTTGCT 
GCCTCGGAAG GTTTAATCAA CATGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001294947.1
CDS559..1545
Translation

Target ORF information:

RefSeq Version NM_001308018.1
Organism Homo sapiens(human)
Definition Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001308018.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTTGATCC AGGTATGCCT GTATTTTTAC TGTAAATTTC TGTGGCGCTG CCTGAAATTT 
GTAATGAGGA AGCTAACTGG AAGATGTGAA CTACAACGGA TCTGTTATAA TACCAAGCCG 
GGAGCTTCTA GAACCATGAA AATCGAAACA TCACTGAGGG ATTCTAAAAG TAAGCTGTTG 
CAGACTTCTG TGAGTGTTCA CCCCGACGCT ATTGAAAAAA CTATAGAAGA TATCATGGAA 
CTGAAAAAAA TTAATCCTGA CGTAAATCCA CAGCTGGGAA TCTCTCTTCA GGCTTGCCTT 
CTGCAAATCG TTGGGTACAG GAACCTTATT GCAGATGTGG AAAAACTGCG TAGAGAGGCC 
TATGATTCTG ATAATCCCCA ACATGAAGAA ATGCTTTTGA AGTTATGGAA ATTCTTGAAG 
CCCAATACTC CACTGGAATC TCGGATTTCT AAGCAGTGGT GTGAAATTGG TTTCCAAGGT 
GATGATCCTA AAACAGACTT TCGAGGAATG GGACTTCTGG GACTGTACAA TTTGCAGTAT 
TTCGCGGAAA GGGATGCCAC AGCAGCTCAG CAGGTCCTGT CTGACTCTCT TCATCCGAAA 
TGCAGGGATA TCACTAAAGA AGAAATAAGC AAATTCAGCA AAGCAGAATG GGAGAAGAAA 
AGGATGGATA AGGCAATTGG GTACTCATTT GCAATTGTGG GCATCAATAT AACTGACCTG 
GCATATAATC TACTGGTCAG CGGAGCTCTA AAAACCCATT TCTACAATAT CGCCCCAGAA 
GCTCCAACAT TGTCTCACTT TCAGCAAACA TTCTGCTATT TGATGCATGA ATTTCATAAG 
TTTTGGATCG AAGAGGACCC CATGGACATA ATGGAATTTA ATCGTGTGAG GGAGAAATTC 
CGCAAGAGGA TCATCAAACA GCTGCAGAAC CCAGACATGG CGCTGTGCCC ACATTTTGCT 
GCCTCGGAAG GTTTAATCAA CATGTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu31807
Clone ID Related Accession (Same CDS sequence) NM_001130037.1
Accession Version NM_001130037.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 981bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-03
Organism Homo sapiens(human)
Product ELMO domain-containing protein 1 isoform 2
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AP000889.6 and AP002353.4. Transcript Variant: This variant (2) lacks an in-frame exon, compared to variant 1. It encodes isoform 2 which is shorter than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1803616.134017.1, SRR1803611.70420.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2146411 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAAGCACT TCCTGAGAAT GTTGATCCAG GTATGCCTGT ATTTTTACTG TAAATTTCTG 
TGGCGCTGCC TGAAATTTGT AATGAGGAAG CTAACTGGAA GATGTGAACT ACAACGGATC 
TGTTATAATA CCAAGCCGGG AGCTTCTAGA ACCATGAAAA TCGAAACATC ACTGAGGGAT 
TCTAAAAGTA AGCTGTTGCA GACTTCTGTG AGTGTTCACC CCGACGCTAT TGAAAAAACT 
ATAGAAGATA TCATGGAACT GAAAAAAATT AATCCTGACG TAAATCCACA GCTGGGAATC 
TCTCTTCAGG CTTGCCTTCT GCAAATCGTT GGGTACAGGA ACCTTATTGC AGATGTGGAA 
AAACTGCGTA GAGAGGCCTA TGATTCTGAT AATCCCCAAC ATGAAGAAAT GCTTTTGAAG 
TTATGGAAAT TCTTGAAGCC CAATACTCCA CTGGAATCTC GGATTTCTAA GCAGTGGTGT 
GAAATTGGTT TCCAAGGTGA TGATCCTAAA ACAGACTTTC GAGGAATGGG ACTTCTGGGA 
CTGTACAATT TGCAGTATTT CGCGGAAAGG GATGCCACAG CAGCTCAGCA GGTCCTGTCT 
GACTCTCTTC ATCCGAAATG CAGCAAATTC AGCAAAGCAG AATGGGAGAA GAAAAGGATG 
GATAAGGCAA TTGGGTACTC ATTTGCAATT GTGGGCATCA ATATAACTGA CCTGGCATAT 
AATCTACTGG TCAGCGGAGC TCTAAAAACC CATTTCTACA ATATCGCCCC AGAAGCTCCA 
ACATTGTCTC ACTTTCAGCA AACATTCTGC TATTTGATGC ATGAATTTCA TAAGTTTTGG 
ATCGAAGAGG ACCCCATGGA CATAATGGAA TTTAATCGTG TGAGGGAGAA ATTCCGCAAG 
AGGATCATCA AACAGCTGCA GAACCCAGAC ATGGCGCTGT GCCCACATTT TGCTGCCTCG 
GAAGGTTTAA TCAACATGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001123509.1
CDS405..1385
Translation

Target ORF information:

RefSeq Version NM_001130037.1
Organism Homo sapiens(human)
Definition Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001130037.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGAAGCACT TCCTGAGAAT GTTGATCCAG GTATGCCTGT ATTTTTACTG TAAATTTCTG 
TGGCGCTGCC TGAAATTTGT AATGAGGAAG CTAACTGGAA GATGTGAACT ACAACGGATC 
TGTTATAATA CCAAGCCGGG AGCTTCTAGA ACCATGAAAA TCGAAACATC ACTGAGGGAT 
TCTAAAAGTA AGCTGTTGCA GACTTCTGTG AGTGTTCACC CCGACGCTAT TGAAAAAACT 
ATAGAAGATA TCATGGAACT GAAAAAAATT AATCCTGACG TAAATCCACA GCTGGGAATC 
TCTCTTCAGG CTTGCCTTCT GCAAATCGTT GGGTACAGGA ACCTTATTGC AGATGTGGAA 
AAACTGCGTA GAGAGGCCTA TGATTCTGAT AATCCCCAAC ATGAAGAAAT GCTTTTGAAG 
TTATGGAAAT TCTTGAAGCC CAATACTCCA CTGGAATCTC GGATTTCTAA GCAGTGGTGT 
GAAATTGGTT TCCAAGGTGA TGATCCTAAA ACAGACTTTC GAGGAATGGG ACTTCTGGGA 
CTGTACAATT TGCAGTATTT CGCGGAAAGG GATGCCACAG CAGCTCAGCA GGTCCTGTCT 
GACTCTCTTC ATCCGAAATG CAGCAAATTC AGCAAAGCAG AATGGGAGAA GAAAAGGATG 
GATAAGGCAA TTGGGTACTC ATTTGCAATT GTGGGCATCA ATATAACTGA CCTGGCATAT 
AATCTACTGG TCAGCGGAGC TCTAAAAACC CATTTCTACA ATATCGCCCC AGAAGCTCCA 
ACATTGTCTC ACTTTCAGCA AACATTCTGC TATTTGATGC ATGAATTTCA TAAGTTTTGG 
ATCGAAGAGG ACCCCATGGA CATAATGGAA TTTAATCGTG TGAGGGAGAA ATTCCGCAAG 
AGGATCATCA AACAGCTGCA GAACCCAGAC ATGGCGCTGT GCCCACATTT TGCTGCCTCG 
GAAGGTTTAA TCAACATGTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu92361
Clone ID Related Accession (Same CDS sequence) XM_017017994.1 , XM_017017995.1 , XM_017017994.2 , XM_017017995.2
Accession Version XM_017017994.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 963bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-05
Organism Homo sapiens(human)
Product ELMO domain-containing protein 1 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTTGATCC AGGTATGCCT GTATTTTTAC TGTAAATTTC TGTGGCGCTG CCTGAAATTT 
GTAATGAGGA AGCTAACTGG AAGATGTGAA CTACAACGGA TCTGTTATAA TACCAAGCCG 
GGAGCTTCTA GAACCATGAA AATCGAAACA TCACTGAGGG ATTCTAAAAG TAAGCTGTTG 
CAGACTTCTG TGAGTGTTCA CCCCGACGCT ATTGAAAAAA CTATAGAAGA TATCATGGAA 
CTGAAAAAAA TTAATCCTGA CGTAAATCCA CAGCTGGGAA TCTCTCTTCA GGCTTGCCTT 
CTGCAAATCG TTGGGTACAG GAACCTTATT GCAGATGTGG AAAAACTGCG TAGAGAGGCC 
TATGATTCTG ATAATCCCCA ACATGAAGAA ATGCTTTTGA AGTTATGGAA ATTCTTGAAG 
CCCAATACTC CACTGGAATC TCGGATTTCT AAGCAGTGGT GTGAAATTGG TTTCCAAGGT 
GATGATCCTA AAACAGACTT TCGAGGAATG GGACTTCTGG GACTGTACAA TTTGCAGTAT 
TTCGCGGAAA GGGATGCCAC AGCAGCTCAG CAGGTCCTGT CTGACTCTCT TCATCCGAAA 
TGCAGCAAAT TCAGCAAAGC AGAATGGGAG AAGAAAAGGA TGGATAAGGC AATTGGGTAC 
TCATTTGCAA TTGTGGGCAT CAATATAACT GACCTGGCAT ATAATCTACT GGTCAGCGGA 
GCTCTAAAAA CCCATTTCTA CAATATCGCC CCAGAAGCTC CAACATTGTC TCACTTTCAG 
CAAACATTCT GCTATTTGAT GCATGAATTT CATAAGTTTT GGATCGAAGA GGACCCCATG 
GACATAATGG AATTTAATCG TGTGAGGGAG AAATTCCGCA AGAGGATCAT CAAACAGCTG 
CAGAACCCAG ACATGGCGCT GTGCCCACAT TTTGCTGCCT CGGAAGGTTT AATCAACATG 
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016873483.1
CDS554..1516
Translation

Target ORF information:

RefSeq Version XM_017017994.1
Organism Homo sapiens(human)
Definition Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017017994.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTTGATCC AGGTATGCCT GTATTTTTAC TGTAAATTTC TGTGGCGCTG CCTGAAATTT 
GTAATGAGGA AGCTAACTGG AAGATGTGAA CTACAACGGA TCTGTTATAA TACCAAGCCG 
GGAGCTTCTA GAACCATGAA AATCGAAACA TCACTGAGGG ATTCTAAAAG TAAGCTGTTG 
CAGACTTCTG TGAGTGTTCA CCCCGACGCT ATTGAAAAAA CTATAGAAGA TATCATGGAA 
CTGAAAAAAA TTAATCCTGA CGTAAATCCA CAGCTGGGAA TCTCTCTTCA GGCTTGCCTT 
CTGCAAATCG TTGGGTACAG GAACCTTATT GCAGATGTGG AAAAACTGCG TAGAGAGGCC 
TATGATTCTG ATAATCCCCA ACATGAAGAA ATGCTTTTGA AGTTATGGAA ATTCTTGAAG 
CCCAATACTC CACTGGAATC TCGGATTTCT AAGCAGTGGT GTGAAATTGG TTTCCAAGGT 
GATGATCCTA AAACAGACTT TCGAGGAATG GGACTTCTGG GACTGTACAA TTTGCAGTAT 
TTCGCGGAAA GGGATGCCAC AGCAGCTCAG CAGGTCCTGT CTGACTCTCT TCATCCGAAA 
TGCAGCAAAT TCAGCAAAGC AGAATGGGAG AAGAAAAGGA TGGATAAGGC AATTGGGTAC 
TCATTTGCAA TTGTGGGCAT CAATATAACT GACCTGGCAT ATAATCTACT GGTCAGCGGA 
GCTCTAAAAA CCCATTTCTA CAATATCGCC CCAGAAGCTC CAACATTGTC TCACTTTCAG 
CAAACATTCT GCTATTTGAT GCATGAATTT CATAAGTTTT GGATCGAAGA GGACCCCATG 
GACATAATGG AATTTAATCG TGTGAGGGAG AAATTCCGCA AGAGGATCAT CAAACAGCTG 
CAGAACCCAG ACATGGCGCT GTGCCCACAT TTTGCTGCCT CGGAAGGTTT AATCAACATG 
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu92361
Clone ID Related Accession (Same CDS sequence) XM_017017994.1 , XM_017017995.1 , XM_017017994.2 , XM_017017995.2
Accession Version XM_017017995.1 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 963bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-05
Organism Homo sapiens(human)
Product ELMO domain-containing protein 1 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTTGATCC AGGTATGCCT GTATTTTTAC TGTAAATTTC TGTGGCGCTG CCTGAAATTT 
GTAATGAGGA AGCTAACTGG AAGATGTGAA CTACAACGGA TCTGTTATAA TACCAAGCCG 
GGAGCTTCTA GAACCATGAA AATCGAAACA TCACTGAGGG ATTCTAAAAG TAAGCTGTTG 
CAGACTTCTG TGAGTGTTCA CCCCGACGCT ATTGAAAAAA CTATAGAAGA TATCATGGAA 
CTGAAAAAAA TTAATCCTGA CGTAAATCCA CAGCTGGGAA TCTCTCTTCA GGCTTGCCTT 
CTGCAAATCG TTGGGTACAG GAACCTTATT GCAGATGTGG AAAAACTGCG TAGAGAGGCC 
TATGATTCTG ATAATCCCCA ACATGAAGAA ATGCTTTTGA AGTTATGGAA ATTCTTGAAG 
CCCAATACTC CACTGGAATC TCGGATTTCT AAGCAGTGGT GTGAAATTGG TTTCCAAGGT 
GATGATCCTA AAACAGACTT TCGAGGAATG GGACTTCTGG GACTGTACAA TTTGCAGTAT 
TTCGCGGAAA GGGATGCCAC AGCAGCTCAG CAGGTCCTGT CTGACTCTCT TCATCCGAAA 
TGCAGCAAAT TCAGCAAAGC AGAATGGGAG AAGAAAAGGA TGGATAAGGC AATTGGGTAC 
TCATTTGCAA TTGTGGGCAT CAATATAACT GACCTGGCAT ATAATCTACT GGTCAGCGGA 
GCTCTAAAAA CCCATTTCTA CAATATCGCC CCAGAAGCTC CAACATTGTC TCACTTTCAG 
CAAACATTCT GCTATTTGAT GCATGAATTT CATAAGTTTT GGATCGAAGA GGACCCCATG 
GACATAATGG AATTTAATCG TGTGAGGGAG AAATTCCGCA AGAGGATCAT CAAACAGCTG 
CAGAACCCAG ACATGGCGCT GTGCCCACAT TTTGCTGCCT CGGAAGGTTT AATCAACATG 
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016873484.1
CDS304..1266
Translation

Target ORF information:

RefSeq Version XM_017017995.1
Organism Homo sapiens(human)
Definition Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017017995.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTTGATCC AGGTATGCCT GTATTTTTAC TGTAAATTTC TGTGGCGCTG CCTGAAATTT 
GTAATGAGGA AGCTAACTGG AAGATGTGAA CTACAACGGA TCTGTTATAA TACCAAGCCG 
GGAGCTTCTA GAACCATGAA AATCGAAACA TCACTGAGGG ATTCTAAAAG TAAGCTGTTG 
CAGACTTCTG TGAGTGTTCA CCCCGACGCT ATTGAAAAAA CTATAGAAGA TATCATGGAA 
CTGAAAAAAA TTAATCCTGA CGTAAATCCA CAGCTGGGAA TCTCTCTTCA GGCTTGCCTT 
CTGCAAATCG TTGGGTACAG GAACCTTATT GCAGATGTGG AAAAACTGCG TAGAGAGGCC 
TATGATTCTG ATAATCCCCA ACATGAAGAA ATGCTTTTGA AGTTATGGAA ATTCTTGAAG 
CCCAATACTC CACTGGAATC TCGGATTTCT AAGCAGTGGT GTGAAATTGG TTTCCAAGGT 
GATGATCCTA AAACAGACTT TCGAGGAATG GGACTTCTGG GACTGTACAA TTTGCAGTAT 
TTCGCGGAAA GGGATGCCAC AGCAGCTCAG CAGGTCCTGT CTGACTCTCT TCATCCGAAA 
TGCAGCAAAT TCAGCAAAGC AGAATGGGAG AAGAAAAGGA TGGATAAGGC AATTGGGTAC 
TCATTTGCAA TTGTGGGCAT CAATATAACT GACCTGGCAT ATAATCTACT GGTCAGCGGA 
GCTCTAAAAA CCCATTTCTA CAATATCGCC CCAGAAGCTC CAACATTGTC TCACTTTCAG 
CAAACATTCT GCTATTTGAT GCATGAATTT CATAAGTTTT GGATCGAAGA GGACCCCATG 
GACATAATGG AATTTAATCG TGTGAGGGAG AAATTCCGCA AGAGGATCAT CAAACAGCTG 
CAGAACCCAG ACATGGCGCT GTGCCCACAT TTTGCTGCCT CGGAAGGTTT AATCAACATG 
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu92361
Clone ID Related Accession (Same CDS sequence) XM_017017994.1 , XM_017017995.1 , XM_017017994.2 , XM_017017995.2
Accession Version XM_017017994.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 963bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product ELMO domain-containing protein 1 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017017994.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTTGATCC AGGTATGCCT GTATTTTTAC TGTAAATTTC TGTGGCGCTG CCTGAAATTT 
GTAATGAGGA AGCTAACTGG AAGATGTGAA CTACAACGGA TCTGTTATAA TACCAAGCCG 
GGAGCTTCTA GAACCATGAA AATCGAAACA TCACTGAGGG ATTCTAAAAG TAAGCTGTTG 
CAGACTTCTG TGAGTGTTCA CCCCGACGCT ATTGAAAAAA CTATAGAAGA TATCATGGAA 
CTGAAAAAAA TTAATCCTGA CGTAAATCCA CAGCTGGGAA TCTCTCTTCA GGCTTGCCTT 
CTGCAAATCG TTGGGTACAG GAACCTTATT GCAGATGTGG AAAAACTGCG TAGAGAGGCC 
TATGATTCTG ATAATCCCCA ACATGAAGAA ATGCTTTTGA AGTTATGGAA ATTCTTGAAG 
CCCAATACTC CACTGGAATC TCGGATTTCT AAGCAGTGGT GTGAAATTGG TTTCCAAGGT 
GATGATCCTA AAACAGACTT TCGAGGAATG GGACTTCTGG GACTGTACAA TTTGCAGTAT 
TTCGCGGAAA GGGATGCCAC AGCAGCTCAG CAGGTCCTGT CTGACTCTCT TCATCCGAAA 
TGCAGCAAAT TCAGCAAAGC AGAATGGGAG AAGAAAAGGA TGGATAAGGC AATTGGGTAC 
TCATTTGCAA TTGTGGGCAT CAATATAACT GACCTGGCAT ATAATCTACT GGTCAGCGGA 
GCTCTAAAAA CCCATTTCTA CAATATCGCC CCAGAAGCTC CAACATTGTC TCACTTTCAG 
CAAACATTCT GCTATTTGAT GCATGAATTT CATAAGTTTT GGATCGAAGA GGACCCCATG 
GACATAATGG AATTTAATCG TGTGAGGGAG AAATTCCGCA AGAGGATCAT CAAACAGCTG 
CAGAACCCAG ACATGGCGCT GTGCCCACAT TTTGCTGCCT CGGAAGGTTT AATCAACATG 
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016873483.1
CDS641..1603
Translation

Target ORF information:

RefSeq Version XM_017017994.2
Organism Homo sapiens(human)
Definition Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017017994.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTTGATCC AGGTATGCCT GTATTTTTAC TGTAAATTTC TGTGGCGCTG CCTGAAATTT 
GTAATGAGGA AGCTAACTGG AAGATGTGAA CTACAACGGA TCTGTTATAA TACCAAGCCG 
GGAGCTTCTA GAACCATGAA AATCGAAACA TCACTGAGGG ATTCTAAAAG TAAGCTGTTG 
CAGACTTCTG TGAGTGTTCA CCCCGACGCT ATTGAAAAAA CTATAGAAGA TATCATGGAA 
CTGAAAAAAA TTAATCCTGA CGTAAATCCA CAGCTGGGAA TCTCTCTTCA GGCTTGCCTT 
CTGCAAATCG TTGGGTACAG GAACCTTATT GCAGATGTGG AAAAACTGCG TAGAGAGGCC 
TATGATTCTG ATAATCCCCA ACATGAAGAA ATGCTTTTGA AGTTATGGAA ATTCTTGAAG 
CCCAATACTC CACTGGAATC TCGGATTTCT AAGCAGTGGT GTGAAATTGG TTTCCAAGGT 
GATGATCCTA AAACAGACTT TCGAGGAATG GGACTTCTGG GACTGTACAA TTTGCAGTAT 
TTCGCGGAAA GGGATGCCAC AGCAGCTCAG CAGGTCCTGT CTGACTCTCT TCATCCGAAA 
TGCAGCAAAT TCAGCAAAGC AGAATGGGAG AAGAAAAGGA TGGATAAGGC AATTGGGTAC 
TCATTTGCAA TTGTGGGCAT CAATATAACT GACCTGGCAT ATAATCTACT GGTCAGCGGA 
GCTCTAAAAA CCCATTTCTA CAATATCGCC CCAGAAGCTC CAACATTGTC TCACTTTCAG 
CAAACATTCT GCTATTTGAT GCATGAATTT CATAAGTTTT GGATCGAAGA GGACCCCATG 
GACATAATGG AATTTAATCG TGTGAGGGAG AAATTCCGCA AGAGGATCAT CAAACAGCTG 
CAGAACCCAG ACATGGCGCT GTGCCCACAT TTTGCTGCCT CGGAAGGTTT AATCAACATG 
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu92361
Clone ID Related Accession (Same CDS sequence) XM_017017994.1 , XM_017017995.1 , XM_017017994.2 , XM_017017995.2
Accession Version XM_017017995.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 963bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-05
Organism Homo sapiens(human)
Product ELMO domain-containing protein 1 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000011.10) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017017995.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTTGATCC AGGTATGCCT GTATTTTTAC TGTAAATTTC TGTGGCGCTG CCTGAAATTT 
GTAATGAGGA AGCTAACTGG AAGATGTGAA CTACAACGGA TCTGTTATAA TACCAAGCCG 
GGAGCTTCTA GAACCATGAA AATCGAAACA TCACTGAGGG ATTCTAAAAG TAAGCTGTTG 
CAGACTTCTG TGAGTGTTCA CCCCGACGCT ATTGAAAAAA CTATAGAAGA TATCATGGAA 
CTGAAAAAAA TTAATCCTGA CGTAAATCCA CAGCTGGGAA TCTCTCTTCA GGCTTGCCTT 
CTGCAAATCG TTGGGTACAG GAACCTTATT GCAGATGTGG AAAAACTGCG TAGAGAGGCC 
TATGATTCTG ATAATCCCCA ACATGAAGAA ATGCTTTTGA AGTTATGGAA ATTCTTGAAG 
CCCAATACTC CACTGGAATC TCGGATTTCT AAGCAGTGGT GTGAAATTGG TTTCCAAGGT 
GATGATCCTA AAACAGACTT TCGAGGAATG GGACTTCTGG GACTGTACAA TTTGCAGTAT 
TTCGCGGAAA GGGATGCCAC AGCAGCTCAG CAGGTCCTGT CTGACTCTCT TCATCCGAAA 
TGCAGCAAAT TCAGCAAAGC AGAATGGGAG AAGAAAAGGA TGGATAAGGC AATTGGGTAC 
TCATTTGCAA TTGTGGGCAT CAATATAACT GACCTGGCAT ATAATCTACT GGTCAGCGGA 
GCTCTAAAAA CCCATTTCTA CAATATCGCC CCAGAAGCTC CAACATTGTC TCACTTTCAG 
CAAACATTCT GCTATTTGAT GCATGAATTT CATAAGTTTT GGATCGAAGA GGACCCCATG 
GACATAATGG AATTTAATCG TGTGAGGGAG AAATTCCGCA AGAGGATCAT CAAACAGCTG 
CAGAACCCAG ACATGGCGCT GTGCCCACAT TTTGCTGCCT CGGAAGGTTT AATCAACATG 
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016873484.1
CDS543..1505
Translation

Target ORF information:

RefSeq Version XM_017017995.2
Organism Homo sapiens(human)
Definition Homo sapiens ELMO domain containing 1 (ELMOD1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017017995.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTTGATCC AGGTATGCCT GTATTTTTAC TGTAAATTTC TGTGGCGCTG CCTGAAATTT 
GTAATGAGGA AGCTAACTGG AAGATGTGAA CTACAACGGA TCTGTTATAA TACCAAGCCG 
GGAGCTTCTA GAACCATGAA AATCGAAACA TCACTGAGGG ATTCTAAAAG TAAGCTGTTG 
CAGACTTCTG TGAGTGTTCA CCCCGACGCT ATTGAAAAAA CTATAGAAGA TATCATGGAA 
CTGAAAAAAA TTAATCCTGA CGTAAATCCA CAGCTGGGAA TCTCTCTTCA GGCTTGCCTT 
CTGCAAATCG TTGGGTACAG GAACCTTATT GCAGATGTGG AAAAACTGCG TAGAGAGGCC 
TATGATTCTG ATAATCCCCA ACATGAAGAA ATGCTTTTGA AGTTATGGAA ATTCTTGAAG 
CCCAATACTC CACTGGAATC TCGGATTTCT AAGCAGTGGT GTGAAATTGG TTTCCAAGGT 
GATGATCCTA AAACAGACTT TCGAGGAATG GGACTTCTGG GACTGTACAA TTTGCAGTAT 
TTCGCGGAAA GGGATGCCAC AGCAGCTCAG CAGGTCCTGT CTGACTCTCT TCATCCGAAA 
TGCAGCAAAT TCAGCAAAGC AGAATGGGAG AAGAAAAGGA TGGATAAGGC AATTGGGTAC 
TCATTTGCAA TTGTGGGCAT CAATATAACT GACCTGGCAT ATAATCTACT GGTCAGCGGA 
GCTCTAAAAA CCCATTTCTA CAATATCGCC CCAGAAGCTC CAACATTGTC TCACTTTCAG 
CAAACATTCT GCTATTTGAT GCATGAATTT CATAAGTTTT GGATCGAAGA GGACCCCATG 
GACATAATGG AATTTAATCG TGTGAGGGAG AAATTCCGCA AGAGGATCAT CAAACAGCTG 
CAGAACCCAG ACATGGCGCT GTGCCCACAT TTTGCTGCCT CGGAAGGTTT AATCAACATG 
TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

ELMOD1 stimulates ARF6-GTP hydrolysis to stabilize apical structures in developing vestibular hair cells.
The Journal of neuroscience : the official journal of the Society for Neuroscience(2017 Dec)
Krey JF,Dumont RA,Wilmarth PA,David LL,Johnson KR,Barr-Gillespie PG


book

Cell adhesion controlled by adhesion G protein-coupled receptor GPR124/ADGRA2 is mediated by a protein complex comprising intersectins and Elmo-Dock.
The Journal of biological chemistry292(29)12178-12191(2017 07)
Hern?ndez-V?squez MN,Adame-Garc?a SR,Hamoud N,Chidiac R,Reyes-Cruz G,Gratton JP,C?t? JF,V?zquez-Prado J


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Characterization of recombinant ELMOD (cell engulfment and motility domain) proteins as GTPase-activating proteins (GAPs) for ARF family GTPases.
The Journal of biological chemistry289(16)11111-21(2014 Apr)
Ivanova AA,East MP,Yi SL,Kahn RA


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High-content genome-wide RNAi screens identify regulators of parkin upstream of mitophagy.
Nature504(7479)291-5(2013 Dec)
Hasson SA,Kane LA,Yamano K,Huang CH,Sliter DA,Buehler E,Wang C,Heman-Ackah SM,Hessa T,Guha R,Martin SE,Youle RJ


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An approach based on a genome-wide association study reveals candidate loci for narcolepsy.
Human genetics128(4)433-41(2010 Oct)
Shimada M,Miyagawa T,Kawashima M,Tanaka S,Honda Y,Honda M,Tokunaga K