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NEUROD4 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol NEUROD4
Entrez Gene ID 58158
Full Name neuronal differentiation 4
Synonyms ATH-3,ATH3,Atoh3,MATH-3,MATH3,bHLHa4
General protein information
Preferred Names

neuronal differentiation 4

Names

neurogenic differentiation factor 4
class A basic helix-loop-helix protein 4
neurogenic differentiation 4
protein atonal homolog 3
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

12

12q13.2
Disorder MIM:

611635


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_021191.2 NP_067014.2 neurogenic differentiation factor 4
NM_021191.3 NP_067014.2 neurogenic differentiation factor 4

Pathways from BioSystems


Homologies


Homo sapiens (human) NEUROD4 NP_067014.2
Danio rerio (zebrafish) neurod4 NP_739568.1
Bos taurus (cattle) NEUROD4 XP_002687669.1
Pan troglodytes (chimpanzee) NEUROD4 XP_522415.2
Canis lupus familiaris (dog) NEUROD4 XP_003433599.1
Mus musculus (house mouse) Neurod4 NP_031527.1
Xenopus tropicalis (tropical clawed frog) neurod4 NP_001124513.1
NEUROD4 XP_001110416.1
Rattus norvegicus (Norway rat) Neurod4 NP_001099412.1
Gallus gallus (chicken) NEUROD4 NP_990407.1

Gene Ontology


Bibliography

Related articles in PubMed

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.
Gratac?s M, Costas J, de Cid R, Bay?s M, Gonz?lez JR, Baca-Garc?a E, de Diego Y, Fern?ndez-Aranda F, Fern?ndez-Piqueras J, Guitart M, Mart?n-Santos R, Martorell L, Mench?n JM, Roca M, S?iz-Ruiz J, Sanju?n J, Torrens M, Urretavizcaya M, Valero J, Vilella E, Estivill X, Carracedo A,
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics150B(6)808-16(2009 Sep)

A census of human transcription factors: function, expression and evolution.
Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM
Nature reviews. Genetics10(4)252-63(2009 04)

beta-cell transcription factors and diabetes: no evidence for diabetes-associated mutations in the gene encoding the basic helix-loop-helix transcription factor neurogenic differentiation 4 (NEUROD4) in Japanese patients with MODY.
Horikawa Y, Horikawa Y, Cox NJ, Iwasaki N, Ogata M, Iwamoto Y, Schwitzgebel V, German MS, Bell GI
Diabetes49(11)1955-7(2000 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.

Observational study of gene-disease association. (HuGE Navigator)
Title: Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.

The following NEUROD4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NEUROD4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu29907 NM_021191.3
Latest version!		 Homo sapiens neuronal differentiation 4 (NEUROD4), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $154.50-$216.30
$309.00
View Old Accession Versions >>
OHu29907 NM_021191.2 Homo sapiens neuronal differentiation 4 (NEUROD4), mRNA. pcDNA3.1+/C-(K)DYK or customized vector
in pcDNA3.1+/C-(K)DYK		 $154.50-$216.30
$309.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu29907
Clone ID Related Accession (Same CDS sequence) NM_021191.2 , NM_021191.3
Accession Version NM_021191.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 996bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-01
Organism Homo sapiens(human)
Product neurogenic differentiation factor 4
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA768001.1, DA417566.1, BC040961.1 and BM683125.1. On Jul 25, 2007 this sequence version replaced NM_021191.1. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.165175.1, AK314136.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145544, SAMEA2146411 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCAAAAA CTTTTGTAAA ATCCAAGGAG ATGGGAGAGC TAGTCAACAC ACCATCCTGG 
ATGGATAAAG GTCTGGGCTC CCAAAATGAG GTGAAGGAGG AAGAGAGCAG ACCAGGTACT 
TATGGGATGC TCAGCAGCTT AACTGAAGAG CATGACAGTA TTGAGGAAGA AGAAGAAGAG 
GAAGAAGATG GGGAGAAACC TAAGAGAAGG GGTCCCAAGA AAAAGAAGAT GACCAAAGCT 
CGCCTTGAGA GATTCAGGGC TCGAAGAGTC AAGGCTAATG CCAGAGAACG GACCCGGATG 
CATGGCCTGA ATGACGCCCT GGATAACCTG AGGCGAGTCA TGCCATGCTA CTCTAAAACC 
CAAAAACTTT CCAAGATAGA GACTCTTAGA CTGGCCAGGA ACTATATTTG GGCTTTATCT 
GAAGTCCTGG AGACTGGCCA GACACCTGAA GGGAAAGGCT TTGTGGAGAT GCTGTGTAAA 
GGGCTCTCTC AGCCCACAAG CAACCTGGTG GCTGGATGTC TCCAACTGGG CCCTCAGTCT 
GTCCTCCTGG AGAAGCACGA GGATAAATCT CCTATTTGTG ACTCTGCCAT CTCTGTCCAC 
AACTTCAACT ATCAGTCTCC GGGGCTTCCT AGCCCTCCTT ATGGTCATAT GGAAACACAT 
CTCCTTCATC TCAAGCCCCA AGTATTCAAG AGTTTGGGAG AATCGTCCTT TGGGAGCCAT 
CTGCCTGACT GCAGTACACC CCCTTATGAG GGCCCACTCA CTCCACCCCT GAGCATCAGT 
GGGAACTTCT CCTTGAAGCA AGATGGGTCT CCTGACCTAG AAAAATCCTA CAGCTTCATG 
CCACATTACC CTTCTTCAAG TCTAAGCTCA GGGCATGTGC ATTCAACTCC TTTTCAGGCT 
GGTACCCCCC GTTATGATGT TCCTATAGAC ATGTCCTATG ATTCCTACCC CCATCATGGT 
ATTGGGACCC AACTCAATAC AGTCTTCACT GAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_067014.2
CDS379..1374
Translation

Target ORF information:

RefSeq Version NM_021191.2
Organism Homo sapiens(human)
Definition Homo sapiens neuronal differentiation 4 (NEUROD4), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_021191.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCAAAAA CTTTTGTAAA ATCCAAGGAG ATGGGAGAGC TAGTCAACAC ACCATCCTGG 
ATGGATAAAG GTCTGGGCTC CCAAAATGAG GTGAAGGAGG AAGAGAGCAG ACCAGGTACT 
TATGGGATGC TCAGCAGCTT AACTGAAGAG CATGACAGTA TTGAGGAAGA AGAAGAAGAG 
GAAGAAGATG GGGAGAAACC TAAGAGAAGG GGTCCCAAGA AAAAGAAGAT GACCAAAGCT 
CGCCTTGAGA GATTCAGGGC TCGAAGAGTC AAGGCTAATG CCAGAGAACG GACCCGGATG 
CATGGCCTGA ATGACGCCCT GGATAACCTG AGGCGAGTCA TGCCATGCTA CTCTAAAACC 
CAAAAACTTT CCAAGATAGA GACTCTTAGA CTGGCCAGGA ACTATATTTG GGCTTTATCT 
GAAGTCCTGG AGACTGGCCA GACACCTGAA GGGAAAGGCT TTGTGGAGAT GCTGTGTAAA 
GGGCTCTCTC AGCCCACAAG CAACCTGGTG GCTGGATGTC TCCAACTGGG CCCTCAGTCT 
GTCCTCCTGG AGAAGCACGA GGATAAATCT CCTATTTGTG ACTCTGCCAT CTCTGTCCAC 
AACTTCAACT ATCAGTCTCC GGGGCTTCCT AGCCCTCCTT ATGGTCATAT GGAAACACAT 
CTCCTTCATC TCAAGCCCCA AGTATTCAAG AGTTTGGGAG AATCGTCCTT TGGGAGCCAT 
CTGCCTGACT GCAGTACACC CCCTTATGAG GGCCCACTCA CTCCACCCCT GAGCATCAGT 
GGGAACTTCT CCTTGAAGCA AGATGGGTCT CCTGACCTAG AAAAATCCTA CAGCTTCATG 
CCACATTACC CTTCTTCAAG TCTAAGCTCA GGGCATGTGC ATTCAACTCC TTTTCAGGCT 
GGTACCCCCC GTTATGATGT TCCTATAGAC ATGTCCTATG ATTCCTACCC CCATCATGGT 
ATTGGGACCC AACTCAATAC AGTCTTCACT GAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu29907
Clone ID Related Accession (Same CDS sequence) NM_021191.2 , NM_021191.3
Accession Version NM_021191.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 996bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-06-07
Organism Homo sapiens(human)
Product neurogenic differentiation factor 4
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA768001.1, DA417566.1, BC040961.1 and BM683125.1. On Nov 23, 2018 this sequence version replaced NM_021191.2. ##Evidence-Data-START## Transcript exon combination :: DA607396.1, SRR1803611.165175.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145544, SAMEA2146411 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000242994.4/ ENSP00000242994.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCAAAAA CTTTTGTAAA ATCCAAGGAG ATGGGAGAGC TAGTCAACAC ACCATCCTGG 
ATGGATAAAG GTCTGGGCTC CCAAAATGAG GTGAAGGAGG AAGAGAGCAG ACCAGGTACT 
TATGGGATGC TCAGCAGCTT AACTGAAGAG CATGACAGTA TTGAGGAAGA AGAAGAAGAG 
GAAGAAGATG GGGAGAAACC TAAGAGAAGG GGTCCCAAGA AAAAGAAGAT GACCAAAGCT 
CGCCTTGAGA GATTCAGGGC TCGAAGAGTC AAGGCTAATG CCAGAGAACG GACCCGGATG 
CATGGCCTGA ATGACGCCCT GGATAACCTG AGGCGAGTCA TGCCATGCTA CTCTAAAACC 
CAAAAACTTT CCAAGATAGA GACTCTTAGA CTGGCCAGGA ACTATATTTG GGCTTTATCT 
GAAGTCCTGG AGACTGGCCA GACACCTGAA GGGAAAGGCT TTGTGGAGAT GCTGTGTAAA 
GGGCTCTCTC AGCCCACAAG CAACCTGGTG GCTGGATGTC TCCAACTGGG CCCTCAGTCT 
GTCCTCCTGG AGAAGCACGA GGATAAATCT CCTATTTGTG ACTCTGCCAT CTCTGTCCAC 
AACTTCAACT ATCAGTCTCC GGGGCTTCCT AGCCCTCCTT ATGGTCATAT GGAAACACAT 
CTCCTTCATC TCAAGCCCCA AGTATTCAAG AGTTTGGGAG AATCGTCCTT TGGGAGCCAT 
CTGCCTGACT GCAGTACACC CCCTTATGAG GGCCCACTCA CTCCACCCCT GAGCATCAGT 
GGGAACTTCT CCTTGAAGCA AGATGGGTCT CCTGACCTAG AAAAATCCTA CAGCTTCATG 
CCACATTACC CTTCTTCAAG TCTAAGCTCA GGGCATGTGC ATTCAACTCC TTTTCAGGCT 
GGTACCCCCC GTTATGATGT TCCTATAGAC ATGTCCTATG ATTCCTACCC CCATCATGGT 
ATTGGGACCC AACTCAATAC AGTCTTCACT GAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_067014.2
CDS350..1345
Translation

Target ORF information:

RefSeq Version NM_021191.3
Organism Homo sapiens(human)
Definition Homo sapiens neuronal differentiation 4 (NEUROD4), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_021191.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
ATGTCAAAAA CTTTTGTAAA ATCCAAGGAG ATGGGAGAGC TAGTCAACAC ACCATCCTGG 
ATGGATAAAG GTCTGGGCTC CCAAAATGAG GTGAAGGAGG AAGAGAGCAG ACCAGGTACT 
TATGGGATGC TCAGCAGCTT AACTGAAGAG CATGACAGTA TTGAGGAAGA AGAAGAAGAG 
GAAGAAGATG GGGAGAAACC TAAGAGAAGG GGTCCCAAGA AAAAGAAGAT GACCAAAGCT 
CGCCTTGAGA GATTCAGGGC TCGAAGAGTC AAGGCTAATG CCAGAGAACG GACCCGGATG 
CATGGCCTGA ATGACGCCCT GGATAACCTG AGGCGAGTCA TGCCATGCTA CTCTAAAACC 
CAAAAACTTT CCAAGATAGA GACTCTTAGA CTGGCCAGGA ACTATATTTG GGCTTTATCT 
GAAGTCCTGG AGACTGGCCA GACACCTGAA GGGAAAGGCT TTGTGGAGAT GCTGTGTAAA 
GGGCTCTCTC AGCCCACAAG CAACCTGGTG GCTGGATGTC TCCAACTGGG CCCTCAGTCT 
GTCCTCCTGG AGAAGCACGA GGATAAATCT CCTATTTGTG ACTCTGCCAT CTCTGTCCAC 
AACTTCAACT ATCAGTCTCC GGGGCTTCCT AGCCCTCCTT ATGGTCATAT GGAAACACAT 
CTCCTTCATC TCAAGCCCCA AGTATTCAAG AGTTTGGGAG AATCGTCCTT TGGGAGCCAT 
CTGCCTGACT GCAGTACACC CCCTTATGAG GGCCCACTCA CTCCACCCCT GAGCATCAGT 
GGGAACTTCT CCTTGAAGCA AGATGGGTCT CCTGACCTAG AAAAATCCTA CAGCTTCATG 
CCACATTACC CTTCTTCAAG TCTAAGCTCA GGGCATGTGC ATTCAACTCC TTTTCAGGCT 
GGTACCCCCC GTTATGATGT TCCTATAGAC ATGTCCTATG ATTCCTACCC CCATCATGGT 
ATTGGGACCC AACTCAATAC AGTCTTCACT GAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Identification of new putative susceptibility genes for several psychiatric disorders by association analysis of regulatory and non-synonymous SNPs of 306 genes involved in neurotransmission and neurodevelopment.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics150B(6)808-16(2009 Sep)
Gratac?s M,Costas J,de Cid R,Bay?s M,Gonz?lez JR,Baca-Garc?a E,de Diego Y,Fern?ndez-Aranda F,Fern?ndez-Piqueras J,Guitart M,Mart?n-Santos R,Martorell L,Mench?n JM,Roca M,S?iz-Ruiz J,Sanju?n J,Torrens M,Urretavizcaya M,Valero J,Vilella E,Estivill X,Carracedo A,


book

A census of human transcription factors: function, expression and evolution.
Nature reviews. Genetics10(4)252-63(2009 04)
Vaquerizas JM,Kummerfeld SK,Teichmann SA,Luscombe NM


book

beta-cell transcription factors and diabetes: no evidence for diabetes-associated mutations in the gene encoding the basic helix-loop-helix transcription factor neurogenic differentiation 4 (NEUROD4) in Japanese patients with MODY.
Diabetes49(11)1955-7(2000 Nov)
Horikawa Y,Horikawa Y,Cox NJ,Iwasaki N,Ogata M,Iwamoto Y,Schwitzgebel V,German MS,Bell GI