Gene Symbol | DLGAP3 |
Entrez Gene ID | 58512 |
Full Name | DLG associated protein 3 |
Synonyms | DAP3,SAPAP3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » DLGAP3 cDNA ORF clone
Gene Symbol | DLGAP3 |
Entrez Gene ID | 58512 |
Full Name | DLG associated protein 3 |
Synonyms | DAP3,SAPAP3 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
XM_011541879.2 | XP_011540181.1 | disks large-associated protein 3 isoform X1 |
XM_011541880.2 | XP_011540182.1 | disks large-associated protein 3 isoform X2 |
NM_001080418.3 | NP_001073887.1 | disks large-associated protein 3 |
NM_001080418.2 | NP_001073887.1 | disks large-associated protein 3 |
Homo sapiens (human) | DLGAP3 | NP_001073887.1 |
DLGAP3 | XP_001108687.1 | |
Mus musculus (house mouse) | Dlgap3 | NP_941020.1 |
Pan troglodytes (chimpanzee) | DLGAP3 | XP_003949428.1 |
Bos taurus (cattle) | DLGAP3 | NP_001179367.1 |
Rattus norvegicus (Norway rat) | Dlgap3 | NP_775161.2 |
Xenopus tropicalis (tropical clawed frog) | dlgap3 | NP_001106458.1 |
Danio rerio (zebrafish) | dlgap3 | NP_001038179.1 |
Canis lupus familiaris (dog) | DLGAP3 | XP_532568.4 |
Gallus gallus (chicken) | DLGAP3 | XP_004947837.1 |
Exonic resequencing of the DLGAP3 gene as a candidate gene for schizophrenia.
Li JM, Lu CL, Cheng MC, Luu SU, Hsu SH, Chen CH
Psychiatry research208(1)84-7(2013 Jun)
Synthesis of two SAPAP3 isoforms from a single mRNA is mediated via alternative translational initiation.
Chua JJ, Schob C, Rehbein M, Gkogkas CG, Richter D, Kindler S
Scientific reports2484(2012)
Interaction between genetic variants of DLGAP3 and SLC1A1 affecting the risk of atypical antipsychotics-induced obsessive-compulsive symptoms.
Ryu S, Oh S, Cho EY, Nam HJ, Yoo JH, Park T, Joo YH, Kwon JS, Hong KS
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics156B(8)949-59(2011 Dec)
Investigating SAPAP3 variants in the etiology of obsessive-compulsive disorder and trichotillomania in the South African white population.
Boardman L, van der Merwe L, Lochner C, Kinnear CJ, Seedat S, Stein DJ, Moolman-Smook JC, Hemmings SM
Comprehensive psychiatry52(2)181-7(2011 Mar-Apr)
Family-based genetic association study of DLGAP3 in Tourette Syndrome.
Crane J, Fagerness J, Osiecki L, Gunnell B, Stewart SE, Pauls DL, Scharf JM,
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics156B(1)108-14(2011 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
several rare variants of the DLGAP3 gene were found in this study which may be associated with schizophrenia.
Title: Exonic resequencing of the DLGAP3 gene as a candidate gene for schizophrenia.
This study provides suggestive evidence that DLGAP3 and its interactive effect with SLC1A1 might be involved in susceptibility to developing OC symptoms in schizophrenia patients receiving AAP treatment.
Title: Interaction between genetic variants of DLGAP3 and SLC1A1 affecting the risk of atypical antipsychotics-induced obsessive-compulsive symptoms.
This study generated preliminary evidence to link SAPAP3 variants to the development of earlier onset obsessive-compulsive disorder.
Title: Investigating SAPAP3 variants in the etiology of obsessive-compulsive disorder and trichotillomania in the South African white population.
DLGAP3 remains a promising candidate gene for Tourette Syndrome.
Title: Family-based genetic association study of DLGAP3 in Tourette Syndrome.
Multiple rare SAPAP3 missense variants in trichotillomania and OCD.
Title: Multiple rare SAPAP3 missense variants in trichotillomania and OCD.
The following DLGAP3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DLGAP3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu05448 | |
Clone ID Related Accession (Same CDS sequence) | XM_011541879.2 , NM_001080418.3 , NM_001080418.2 | |
Accession Version | NM_001080418.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2940bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-30 | |
Organism | Homo sapiens(human) | |
Product | disks large-associated protein 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC114490.2 and AL122010.10. On Nov 23, 2018 this sequence version replaced NM_001080418.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000373347.6/ ENSP00000362444.1 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGAGGGGTT ACCATGGCGA CCGAGGCAGC CATCCCCGCC CAGCCCGCTT TGCTGACCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001073887.1 |
CDS | 335..3274 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001080418.3 |
1 | ATGAGGGGTT ACCATGGCGA CCGAGGCAGC CATCCCCGCC CAGCCCGCTT TGCTGACCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu05448 | |
Clone ID Related Accession (Same CDS sequence) | XM_011541879.2 , NM_001080418.3 , NM_001080418.2 | |
Accession Version | NM_001080418.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2940bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-02 | |
Organism | Homo sapiens(human) | |
Product | disks large-associated protein 3 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC114490.2 and AL122010.10. On Sep 26, 2014 this sequence version replaced NM_001080418.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAGGGGTT ACCATGGCGA CCGAGGCAGC CATCCCCGCC CAGCCCGCTT TGCTGACCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001073887.1 |
CDS | 270..3209 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001080418.2 |
1 | ATGAGGGGTT ACCATGGCGA CCGAGGCAGC CATCCCCGCC CAGCCCGCTT TGCTGACCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu05448 | |
Clone ID Related Accession (Same CDS sequence) | XM_011541879.2 , NM_001080418.3 , NM_001080418.2 | |
Accession Version | XM_011541879.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2940bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | disks large-associated protein 3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011541879.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAGGGGTT ACCATGGCGA CCGAGGCAGC CATCCCCGCC CAGCCCGCTT TGCTGACCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011540181.1 |
CDS | 2155..5094 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011541879.2 |
1 | ATGAGGGGTT ACCATGGCGA CCGAGGCAGC CATCCCCGCC CAGCCCGCTT TGCTGACCAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu71008 | |
Clone ID Related Accession (Same CDS sequence) | XM_011541880.2 | |
Accession Version | XM_011541880.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1449bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | disks large-associated protein 3 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011541880.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCGGAGCC ACAGCTACCT CCGGGCCATC CAGGCCGGCT GCTCTCAAGA CGACGACTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011540182.1 |
CDS | 1470..2918 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011541880.2 |
1 | ATGCGGAGCC ACAGCTACCT CCGGGCCATC CAGGCCGGCT GCTCTCAAGA CGACGACTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Exonic resequencing of the DLGAP3 gene as a candidate gene for schizophrenia. |
Synthesis of two SAPAP3 isoforms from a single mRNA is mediated via alternative translational initiation. |
Interaction between genetic variants of DLGAP3 and SLC1A1 affecting the risk of atypical antipsychotics-induced obsessive-compulsive symptoms. |
Investigating SAPAP3 variants in the etiology of obsessive-compulsive disorder and trichotillomania in the South African white population. |
Family-based genetic association study of DLGAP3 in Tourette Syndrome. |