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SFTPC cDNA ORF clone, Homo sapiens (human)

Gene Symbol SFTPC
Entrez Gene ID 6440
Full Name surfactant protein C
Synonyms BRICD6, PSP-C, SFTP2, SMDP2, SP-C
General protein information
Preferred Names
pulmonary surfactant-associated protein C
Names
pulmonary surfactant-associated protein C
SP5
BRICHOS domain containing 6
pulmonary surfactant apoprotein-2 SP-C
pulmonary surfactant-associated proteolipid SPL(Val)
Gene Type protein-coding
Organism Homo sapiens (human)
Genome

8

8p21

Summary This gene encodes the pulmonary-associated surfactant protein C (SPC), an extremely hydrophobic surfactant protein essential for lung function and homeostasis after birth. Pulmonary surfactant is a surface-active lipoprotein complex composed of 90% lipids and 10% proteins which include plasma proteins and apolipoproteins SPA, SPB, SPC and SPD. The surfactant is secreted by the alveolar cells of the lung and maintains the stability of pulmonary tissue by reducing the surface tension of fluids that coat the lung. Multiple mutations in this gene have been identified, which cause pulmonary surfactant metabolism dysfunction type 2, also called pulmonary alveolar proteinosis due to surfactant protein C deficiency, and are associated with interstitial lung disease in older infants, children, and adults. Alternatively spliced transcript variants encoding different protein isoforms have been identified.[provided by RefSeq, Feb 2010]. lac of sum
Disorder MIM:

178620

Disorder Html: Surfactant metabolism dysfunction, pulmonary, 2, 610913 (3)

mRNA and Protein(s)

mRNA Protein Name
XM_006716379 XP_006716442 pulmonary surfactant-associated protein C isoform X1
XM_006716380 XP_006716443 pulmonary surfactant-associated protein C isoform X1
XM_011544612 XP_011542914 pulmonary surfactant-associated protein C isoform X2
XM_011544613 XP_011542915 pulmonary surfactant-associated protein C isoform X2
NM_003018 NP_003009 pulmonary surfactant-associated protein C isoform 1 proprotein
NM_001172357 NP_001165828 pulmonary surfactant-associated protein C isoform 2 proprotein
NM_001172410 NP_001165881 pulmonary surfactant-associated protein C isoform 1 proprotein


Homo sapiens (human) SFTPC NP_001165881.1
Pan troglodytes (chimpanzee) SFTPC XP_519645.2
Macaca mulatta (Rhesus monkey) SFTPC NP_001036224.1
Canis lupus familiaris (dog) SFTPC XP_534578.4
Bos taurus (cattle) SFTPC NP_776887.1
Mus musculus (house mouse) Sftpc NP_035489.2
Rattus norvegicus (Norway rat) Sftpc NP_059038.1
Xenopus (Silurana) tropicalis (western clawed frog) sftpc NP_001122132.2


GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following SFTPC gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SFTPC cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu22858 XM_006716379 PREDICTED: Homo sapiens surfactant protein C (SFTPC), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu22858 XM_006716380 PREDICTED: Homo sapiens surfactant protein C (SFTPC), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu60455 XM_011544612 PREDICTED: Homo sapiens surfactant protein C (SFTPC), transcript variant X3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu60455 XM_011544613 PREDICTED: Homo sapiens surfactant protein C (SFTPC), transcript variant X4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu22601 NM_003018 Homo sapiens surfactant protein C (SFTPC), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $69.30
$99.00
OHu22858 NM_001172357 Homo sapiens surfactant protein C (SFTPC), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu22601 NM_001172410 Homo sapiens surfactant protein C (SFTPC), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $69.30
$99.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu22858
Clone ID Related Accession (Same CDS sequence) NM_001172357 , XM_006716379 , XM_006716380
Accession Version XM_006716379.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 576bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product pulmonary surfactant-associated protein C isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167187.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578815432. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
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301
361
421
481
541
ATGGATGTGG GCAGCAAAGA GGTCCTGATG GAGAGCCCGC CGGACTACTC CGCAGCTCCC 
CGGGGCCGAT TTGGCATTCC CTGCTGCCCA GTGCACCTGA AACGCCTTCT TATCGTGGTG
GTGGTGGTGG TCCTCATCGT CGTGGTGATT GTGGGAGCCC TGCTCATGGG TCTCCACATG
AGCCAGAAAC ACACGGAGAT GGTTCTGGAG ATGAGCATTG GGGCGCCGGA AGCCCAGCAA
CGCCTGGCCC TGAGTGAGCA CCTGGTTACC ACTGCCACCT TCTCCATCGG CTCCACTGGC
CTCGTGGTGT ATGACTACCA GCAGCTGCTG ATCGCCTACA AGCCAGCCCC TGGCACCTGC
TGCTACATCA TGAAGATAGC TCCAGAGAGC ATCCCCAGTC TTGAGGCTCT CACTAGAAAA
GTCCACAACT TCCAGGCCAA GCCCGCAGTG CCTACGTCTA AGCTGGGCCA GGCAGAGGGG
CGAGATGCAG GCTCAGCACC CTCCGGAGGG GACCCGGCCT TCCTGGGCAT GGCCGTGAGC
ACCCTGTGTG GCGAGGTGCC GCTCTACTAC ATCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006716442.1
CDS78..653
Misc Feature(1)78..650(+)
Misc Feature(2)78..356(+)
Misc Feature(3)357..650(+)
Translation

Target ORF information:

RefSeq Version XM_006716379
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens surfactant protein C (SFTPC), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006716379

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGATGTGG GCAGCAAAGA GGTCCTGATG GAGAGCCCGC CGGACTACTC CGCAGCTCCC 
CGGGGCCGAT TTGGCATTCC CTGCTGCCCA GTGCACCTGA AACGCCTTCT TATCGTGGTG
GTGGTGGTGG TCCTCATCGT CGTGGTGATT GTGGGAGCCC TGCTCATGGG TCTCCACATG
AGCCAGAAAC ACACGGAGAT GGTTCTGGAG ATGAGCATTG GGGCGCCGGA AGCCCAGCAA
CGCCTGGCCC TGAGTGAGCA CCTGGTTACC ACTGCCACCT TCTCCATCGG CTCCACTGGC
CTCGTGGTGT ATGACTACCA GCAGCTGCTG ATCGCCTACA AGCCAGCCCC TGGCACCTGC
TGCTACATCA TGAAGATAGC TCCAGAGAGC ATCCCCAGTC TTGAGGCTCT CACTAGAAAA
GTCCACAACT TCCAGGCCAA GCCCGCAGTG CCTACGTCTA AGCTGGGCCA GGCAGAGGGG
CGAGATGCAG GCTCAGCACC CTCCGGAGGG GACCCGGCCT TCCTGGGCAT GGCCGTGAGC
ACCCTGTGTG GCGAGGTGCC GCTCTACTAC ATCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22858
Clone ID Related Accession (Same CDS sequence) NM_001172357 , XM_006716379 , XM_006716380
Accession Version XM_006716380.2 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 576bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product pulmonary surfactant-associated protein C isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167187.2) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 12, 2015 this sequence version replaced gi:578815434. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
ATGGATGTGG GCAGCAAAGA GGTCCTGATG GAGAGCCCGC CGGACTACTC CGCAGCTCCC 
CGGGGCCGAT TTGGCATTCC CTGCTGCCCA GTGCACCTGA AACGCCTTCT TATCGTGGTG
GTGGTGGTGG TCCTCATCGT CGTGGTGATT GTGGGAGCCC TGCTCATGGG TCTCCACATG
AGCCAGAAAC ACACGGAGAT GGTTCTGGAG ATGAGCATTG GGGCGCCGGA AGCCCAGCAA
CGCCTGGCCC TGAGTGAGCA CCTGGTTACC ACTGCCACCT TCTCCATCGG CTCCACTGGC
CTCGTGGTGT ATGACTACCA GCAGCTGCTG ATCGCCTACA AGCCAGCCCC TGGCACCTGC
TGCTACATCA TGAAGATAGC TCCAGAGAGC ATCCCCAGTC TTGAGGCTCT CACTAGAAAA
GTCCACAACT TCCAGGCCAA GCCCGCAGTG CCTACGTCTA AGCTGGGCCA GGCAGAGGGG
CGAGATGCAG GCTCAGCACC CTCCGGAGGG GACCCGGCCT TCCTGGGCAT GGCCGTGAGC
ACCCTGTGTG GCGAGGTGCC GCTCTACTAC ATCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006716443.1
CDS79..654
Misc Feature(1)79..651(+)
Misc Feature(2)79..357(+)
Misc Feature(3)358..651(+)
Translation

Target ORF information:

RefSeq Version XM_006716380
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens surfactant protein C (SFTPC), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_006716380

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGATGTGG GCAGCAAAGA GGTCCTGATG GAGAGCCCGC CGGACTACTC CGCAGCTCCC 
CGGGGCCGAT TTGGCATTCC CTGCTGCCCA GTGCACCTGA AACGCCTTCT TATCGTGGTG
GTGGTGGTGG TCCTCATCGT CGTGGTGATT GTGGGAGCCC TGCTCATGGG TCTCCACATG
AGCCAGAAAC ACACGGAGAT GGTTCTGGAG ATGAGCATTG GGGCGCCGGA AGCCCAGCAA
CGCCTGGCCC TGAGTGAGCA CCTGGTTACC ACTGCCACCT TCTCCATCGG CTCCACTGGC
CTCGTGGTGT ATGACTACCA GCAGCTGCTG ATCGCCTACA AGCCAGCCCC TGGCACCTGC
TGCTACATCA TGAAGATAGC TCCAGAGAGC ATCCCCAGTC TTGAGGCTCT CACTAGAAAA
GTCCACAACT TCCAGGCCAA GCCCGCAGTG CCTACGTCTA AGCTGGGCCA GGCAGAGGGG
CGAGATGCAG GCTCAGCACC CTCCGGAGGG GACCCGGCCT TCCTGGGCAT GGCCGTGAGC
ACCCTGTGTG GCGAGGTGCC GCTCTACTAC ATCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60455
Clone ID Related Accession (Same CDS sequence) XM_011544612 , XM_011544613
Accession Version XM_011544612.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 435bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product pulmonary surfactant-associated protein C isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167187.2) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGGATGTGG GCAGCAAAGA GGTCCTGATG GAGAGCCCGC CGGTTCTGGA GATGAGCATT 
GGGGCGCCGG AAGCCCAGCA ACGCCTGGCC CTGAGTGAGC ACCTGGTTAC CACTGCCACC
TTCTCCATCG GCTCCACTGG CCTCGTGGTG TATGACTACC AGCAGCTGCT GATCGCCTAC
AAGCCAGCCC CTGGCACCTG CTGCTACATC ATGAAGATAG CTCCAGAGAG CATCCCCAGT
CTTGAGGCTC TCACTAGAAA AGTCCACAAC TTCCAGATGG AATGCTCTCT GCAGGCCAAG
CCCGCAGTGC CTACGTCTAA GCTGGGCCAG GCAGAGGGGC GAGATGCAGG CTCAGCACCC
TCCGGAGGGG ACCCGGCCTT CCTGGGCATG GCCGTGAGCA CCCTGTGTGG CGAGGTGCCG
CTCTACTACA TCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011542914.1
CDS95..529
Misc Feature(1)95..526(+)
Misc Feature(2)95..214(+)
Misc Feature(3)215..526(+)
Translation

Target ORF information:

RefSeq Version XM_011544612
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens surfactant protein C (SFTPC), transcript variant X3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011544612

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGATGTGG GCAGCAAAGA GGTCCTGATG GAGAGCCCGC CGGTTCTGGA GATGAGCATT 
GGGGCGCCGG AAGCCCAGCA ACGCCTGGCC CTGAGTGAGC ACCTGGTTAC CACTGCCACC
TTCTCCATCG GCTCCACTGG CCTCGTGGTG TATGACTACC AGCAGCTGCT GATCGCCTAC
AAGCCAGCCC CTGGCACCTG CTGCTACATC ATGAAGATAG CTCCAGAGAG CATCCCCAGT
CTTGAGGCTC TCACTAGAAA AGTCCACAAC TTCCAGATGG AATGCTCTCT GCAGGCCAAG
CCCGCAGTGC CTACGTCTAA GCTGGGCCAG GCAGAGGGGC GAGATGCAGG CTCAGCACCC
TCCGGAGGGG ACCCGGCCTT CCTGGGCATG GCCGTGAGCA CCCTGTGTGG CGAGGTGCCG
CTCTACTACA TCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu60455
Clone ID Related Accession (Same CDS sequence) XM_011544612 , XM_011544613
Accession Version XM_011544613.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 435bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 12-MAR-2015
Organism Homo sapiens (human)
Product pulmonary surfactant-associated protein C isoform X2
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NT_167187.2) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 107 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
ATGGATGTGG GCAGCAAAGA GGTCCTGATG GAGAGCCCGC CGGTTCTGGA GATGAGCATT 
GGGGCGCCGG AAGCCCAGCA ACGCCTGGCC CTGAGTGAGC ACCTGGTTAC CACTGCCACC
TTCTCCATCG GCTCCACTGG CCTCGTGGTG TATGACTACC AGCAGCTGCT GATCGCCTAC
AAGCCAGCCC CTGGCACCTG CTGCTACATC ATGAAGATAG CTCCAGAGAG CATCCCCAGT
CTTGAGGCTC TCACTAGAAA AGTCCACAAC TTCCAGATGG AATGCTCTCT GCAGGCCAAG
CCCGCAGTGC CTACGTCTAA GCTGGGCCAG GCAGAGGGGC GAGATGCAGG CTCAGCACCC
TCCGGAGGGG ACCCGGCCTT CCTGGGCATG GCCGTGAGCA CCCTGTGTGG CGAGGTGCCG
CTCTACTACA TCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011542915.1
CDS97..531
Misc Feature(1)97..528(+)
Misc Feature(2)97..216(+)
Misc Feature(3)217..528(+)
Translation

Target ORF information:

RefSeq Version XM_011544613
Organism Homo sapiens (human)
Definition PREDICTED: Homo sapiens surfactant protein C (SFTPC), transcript variant X4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011544613

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGATGTGG GCAGCAAAGA GGTCCTGATG GAGAGCCCGC CGGTTCTGGA GATGAGCATT 
GGGGCGCCGG AAGCCCAGCA ACGCCTGGCC CTGAGTGAGC ACCTGGTTAC CACTGCCACC
TTCTCCATCG GCTCCACTGG CCTCGTGGTG TATGACTACC AGCAGCTGCT GATCGCCTAC
AAGCCAGCCC CTGGCACCTG CTGCTACATC ATGAAGATAG CTCCAGAGAG CATCCCCAGT
CTTGAGGCTC TCACTAGAAA AGTCCACAAC TTCCAGATGG AATGCTCTCT GCAGGCCAAG
CCCGCAGTGC CTACGTCTAA GCTGGGCCAG GCAGAGGGGC GAGATGCAGG CTCAGCACCC
TCCGGAGGGG ACCCGGCCTT CCTGGGCATG GCCGTGAGCA CCCTGTGTGG CGAGGTGCCG
CTCTACTACA TCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22601
Clone ID Related Accession (Same CDS sequence) NM_001172410 , NM_003018
Accession Version NM_003018.3 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 594bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product pulmonary surfactant-associated protein C isoform 1 proprotein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from J03553.1, BC105594.1, DB537043.1 and J03517.1. This sequence is a reference standard in the RefSeqGene project. On Jun 28, 2007 this sequence version replaced gi:42476334. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: J03517.1, J03553.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
ATGGATGTGG GCAGCAAAGA GGTCCTGATG GAGAGCCCGC CGGACTACTC CGCAGCTCCC 
CGGGGCCGAT TTGGCATTCC CTGCTGCCCA GTGCACCTGA AACGCCTTCT TATCGTGGTG
GTGGTGGTGG TCCTCATCGT CGTGGTGATT GTGGGAGCCC TGCTCATGGG TCTCCACATG
AGCCAGAAAC ACACGGAGAT GGTTCTGGAG ATGAGCATTG GGGCGCCGGA AGCCCAGCAA
CGCCTGGCCC TGAGTGAGCA CCTGGTTACC ACTGCCACCT TCTCCATCGG CTCCACTGGC
CTCGTGGTGT ATGACTACCA GCAGCTGCTG ATCGCCTACA AGCCAGCCCC TGGCACCTGC
TGCTACATCA TGAAGATAGC TCCAGAGAGC ATCCCCAGTC TTGAGGCTCT CACTAGAAAA
GTCCACAACT TCCAGATGGA ATGCTCTCTG CAGGCCAAGC CCGCAGTGCC TACGTCTAAG
CTGGGCCAGG CAGAGGGGCG AGATGCAGGC TCAGCACCCT CCGGAGGGGA CCCGGCCTTC
CTGGGCATGG CCGTGAGCAC CCTGTGTGGC GAGGTGCCGC TCTACTACAT CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_003009.2
CDS159..752
Misc Feature(1)102..104(+)
Misc Feature(2)159..749(+)
Misc Feature(3)159..437(+)
Misc Feature(4)438..749(+)
Exon (1)1..200
Gene:SFTPC
Gene Synonym:
Exon (2)201..359
Gene:SFTPC
Gene Synonym:
Exon (3)360..482
Gene:SFTPC
Gene Synonym:
Exon (4)483..593
Gene:SFTPC
Gene Synonym:
Exon (5)594..770
Gene:SFTPC
Gene Synonym:
Exon (6)771..984
Gene:SFTPC
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_003018
Organism Homo sapiens (human)
Definition Homo sapiens surfactant protein C (SFTPC), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_003018

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGATGTGG GCAGCAAAGA GGTCCTGATG GAGAGCCCGC CGGACTACTC CGCAGCTCCC 
CGGGGCCGAT TTGGCATTCC CTGCTGCCCA GTGCACCTGA AACGCCTTCT TATCGTGGTG
GTGGTGGTGG TCCTCATCGT CGTGGTGATT GTGGGAGCCC TGCTCATGGG TCTCCACATG
AGCCAGAAAC ACACGGAGAT GGTTCTGGAG ATGAGCATTG GGGCGCCGGA AGCCCAGCAA
CGCCTGGCCC TGAGTGAGCA CCTGGTTACC ACTGCCACCT TCTCCATCGG CTCCACTGGC
CTCGTGGTGT ATGACTACCA GCAGCTGCTG ATCGCCTACA AGCCAGCCCC TGGCACCTGC
TGCTACATCA TGAAGATAGC TCCAGAGAGC ATCCCCAGTC TTGAGGCTCT CACTAGAAAA
GTCCACAACT TCCAGATGGA ATGCTCTCTG CAGGCCAAGC CCGCAGTGCC TACGTCTAAG
CTGGGCCAGG CAGAGGGGCG AGATGCAGGC TCAGCACCCT CCGGAGGGGA CCCGGCCTTC
CTGGGCATGG CCGTGAGCAC CCTGTGTGGC GAGGTGCCGC TCTACTACAT CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22858
Clone ID Related Accession (Same CDS sequence) NM_001172357 , XM_006716379 , XM_006716380
Accession Version NM_001172357.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 576bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product pulmonary surfactant-associated protein C isoform 2 proprotein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from J03553.1, BC105594.1 and BM993053.1. Transcript Variant: This variant (3) lacks an in-frame segment in the 3' coding region and has an additional segment in the 3' UTR, as compared to variant 1. The transcript is longer than variant 1, but encodes a shorter isoform (2), as compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC105594.1, BG542819.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
ATGGATGTGG GCAGCAAAGA GGTCCTGATG GAGAGCCCGC CGGACTACTC CGCAGCTCCC 
CGGGGCCGAT TTGGCATTCC CTGCTGCCCA GTGCACCTGA AACGCCTTCT TATCGTGGTG
GTGGTGGTGG TCCTCATCGT CGTGGTGATT GTGGGAGCCC TGCTCATGGG TCTCCACATG
AGCCAGAAAC ACACGGAGAT GGTTCTGGAG ATGAGCATTG GGGCGCCGGA AGCCCAGCAA
CGCCTGGCCC TGAGTGAGCA CCTGGTTACC ACTGCCACCT TCTCCATCGG CTCCACTGGC
CTCGTGGTGT ATGACTACCA GCAGCTGCTG ATCGCCTACA AGCCAGCCCC TGGCACCTGC
TGCTACATCA TGAAGATAGC TCCAGAGAGC ATCCCCAGTC TTGAGGCTCT CACTAGAAAA
GTCCACAACT TCCAGGCCAA GCCCGCAGTG CCTACGTCTA AGCTGGGCCA GGCAGAGGGG
CGAGATGCAG GCTCAGCACC CTCCGGAGGG GACCCGGCCT TCCTGGGCAT GGCCGTGAGC
ACCCTGTGTG GCGAGGTGCC GCTCTACTAC ATCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001165828.1
CDS159..734
Misc Feature(1)102..104(+)
Misc Feature(2)159..731(+)
Misc Feature(3)159..437(+)
Misc Feature(4)438..731(+)
Exon (1)1..200
Gene:SFTPC
Gene Synonym:
Exon (2)201..359
Gene:SFTPC
Gene Synonym:
Exon (3)360..482
Gene:SFTPC
Gene Synonym:
Exon (4)483..593
Gene:SFTPC
Gene Synonym:
Exon (5)594..1172
Gene:SFTPC
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001172357
Organism Homo sapiens (human)
Definition Homo sapiens surfactant protein C (SFTPC), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001172357

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGATGTGG GCAGCAAAGA GGTCCTGATG GAGAGCCCGC CGGACTACTC CGCAGCTCCC 
CGGGGCCGAT TTGGCATTCC CTGCTGCCCA GTGCACCTGA AACGCCTTCT TATCGTGGTG
GTGGTGGTGG TCCTCATCGT CGTGGTGATT GTGGGAGCCC TGCTCATGGG TCTCCACATG
AGCCAGAAAC ACACGGAGAT GGTTCTGGAG ATGAGCATTG GGGCGCCGGA AGCCCAGCAA
CGCCTGGCCC TGAGTGAGCA CCTGGTTACC ACTGCCACCT TCTCCATCGG CTCCACTGGC
CTCGTGGTGT ATGACTACCA GCAGCTGCTG ATCGCCTACA AGCCAGCCCC TGGCACCTGC
TGCTACATCA TGAAGATAGC TCCAGAGAGC ATCCCCAGTC TTGAGGCTCT CACTAGAAAA
GTCCACAACT TCCAGGCCAA GCCCGCAGTG CCTACGTCTA AGCTGGGCCA GGCAGAGGGG
CGAGATGCAG GCTCAGCACC CTCCGGAGGG GACCCGGCCT TCCTGGGCAT GGCCGTGAGC
ACCCTGTGTG GCGAGGTGCC GCTCTACTAC ATCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu22601
Clone ID Related Accession (Same CDS sequence) NM_001172410 , NM_003018
Accession Version NM_001172410.1 Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 594bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 15-MAR-2015
Organism Homo sapiens (human)
Product pulmonary surfactant-associated protein C isoform 1 proprotein
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from J03553.1, BC005913.1, AK315742.1 and BQ027183.1. Transcript Variant: This variant (2) lacks an internal segment in the 3' UTR, as compared to variant 1. Both variants 1 and 2 encode the same isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC005913.1, BG485480.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA2142363 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
ATGGATGTGG GCAGCAAAGA GGTCCTGATG GAGAGCCCGC CGGACTACTC CGCAGCTCCC 
CGGGGCCGAT TTGGCATTCC CTGCTGCCCA GTGCACCTGA AACGCCTTCT TATCGTGGTG
GTGGTGGTGG TCCTCATCGT CGTGGTGATT GTGGGAGCCC TGCTCATGGG TCTCCACATG
AGCCAGAAAC ACACGGAGAT GGTTCTGGAG ATGAGCATTG GGGCGCCGGA AGCCCAGCAA
CGCCTGGCCC TGAGTGAGCA CCTGGTTACC ACTGCCACCT TCTCCATCGG CTCCACTGGC
CTCGTGGTGT ATGACTACCA GCAGCTGCTG ATCGCCTACA AGCCAGCCCC TGGCACCTGC
TGCTACATCA TGAAGATAGC TCCAGAGAGC ATCCCCAGTC TTGAGGCTCT CACTAGAAAA
GTCCACAACT TCCAGATGGA ATGCTCTCTG CAGGCCAAGC CCGCAGTGCC TACGTCTAAG
CTGGGCCAGG CAGAGGGGCG AGATGCAGGC TCAGCACCCT CCGGAGGGGA CCCGGCCTTC
CTGGGCATGG CCGTGAGCAC CCTGTGTGGC GAGGTGCCGC TCTACTACAT CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001165881.1
CDS159..752
Misc Feature(1)102..104(+)
Misc Feature(2)159..749(+)
Misc Feature(3)159..437(+)
Misc Feature(4)438..749(+)
Exon (1)1..200
Gene:SFTPC
Gene Synonym:
Exon (2)201..359
Gene:SFTPC
Gene Synonym:
Exon (3)360..482
Gene:SFTPC
Gene Synonym:
Exon (4)483..593
Gene:SFTPC
Gene Synonym:
Exon (5)594..762
Gene:SFTPC
Gene Synonym:
Exon (6)763..976
Gene:SFTPC
Gene Synonym:
Translation

Target ORF information:

RefSeq Version NM_001172410
Organism Homo sapiens (human)
Definition Homo sapiens surfactant protein C (SFTPC), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001172410

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGATGTGG GCAGCAAAGA GGTCCTGATG GAGAGCCCGC CGGACTACTC CGCAGCTCCC 
CGGGGCCGAT TTGGCATTCC CTGCTGCCCA GTGCACCTGA AACGCCTTCT TATCGTGGTG
GTGGTGGTGG TCCTCATCGT CGTGGTGATT GTGGGAGCCC TGCTCATGGG TCTCCACATG
AGCCAGAAAC ACACGGAGAT GGTTCTGGAG ATGAGCATTG GGGCGCCGGA AGCCCAGCAA
CGCCTGGCCC TGAGTGAGCA CCTGGTTACC ACTGCCACCT TCTCCATCGG CTCCACTGGC
CTCGTGGTGT ATGACTACCA GCAGCTGCTG ATCGCCTACA AGCCAGCCCC TGGCACCTGC
TGCTACATCA TGAAGATAGC TCCAGAGAGC ATCCCCAGTC TTGAGGCTCT CACTAGAAAA
GTCCACAACT TCCAGATGGA ATGCTCTCTG CAGGCCAAGC CCGCAGTGCC TACGTCTAAG
CTGGGCCAGG CAGAGGGGCG AGATGCAGGC TCAGCACCCT CCGGAGGGGA CCCGGCCTTC
CTGGGCATGG CCGTGAGCAC CCTGTGTGGC GAGGTGCCGC TCTACTACAT CTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

 
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