Gene Symbol | NKX2-4 |
Entrez Gene ID | 644524 |
Full Name | NK2 homeobox 4 |
Synonyms | NKX2.4,NKX2D |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » NKX2-4 cDNA ORF clone
gRNAs
Gene Symbol | NKX2-4 |
Entrez Gene ID | 644524 |
Full Name | NK2 homeobox 4 |
Synonyms | NKX2.4,NKX2D |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_033176.1 | NP_149416.1 | homeobox protein Nkx-2.4 |
NM_033176.2 | NP_149416.1 | homeobox protein Nkx-2.4 |
Homo sapiens (human) | NKX2-4 | NP_149416.1 |
Rattus norvegicus (Norway rat) | Nkx2-4 | XP_345446.3 |
Pan troglodytes (chimpanzee) | NKX2-4 | XP_525278.3 |
Xenopus tropicalis (tropical clawed frog) | nkx2-4 | XP_002939478.1 |
Canis lupus familiaris (dog) | NKX2-4 | XP_005635390.1 |
Mus musculus (house mouse) | Nkx2-4 | NP_075993.1 |
Danio rerio (zebrafish) | zgc:171531 | NP_001104636.1 |
Drosophila melanogaster (fruit fly) | scro | NP_001015473.1 |
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus.
Chung SA, Brown EE, Williams AH, Ramos PS, Berthier CC, Bhangale T, Alarcon-Riquelme ME, Behrens TW, Criswell LA, Graham DC, Demirci FY, Edberg JC, Gaffney PM, Harley JB, Jacob CO, Kamboh MI, Kelly JA, Manzi S, Moser-Sivils KL, Russell LP, Petri M, Tsao BP, Vyse TJ, Zidovetzki R, Kretzler M, Kimberly RP, Freedman BI, Graham RR, Langefeld CD,
Journal of the American Society of Nephrology : JASN25(12)2859-70(2014 Dec)
A census of human transcription factors: function, expression and evolution.
Vaquerizas JM, Kummerfeld SK, Teichmann SA, Luscombe NM
Nature reviews. Genetics10(4)252-63(2009 04)
The DNA sequence and comparative analysis of human chromosome 20.
Deloukas P, Matthews LH, Ashurst J, Burton J, Gilbert JG, Jones M, Stavrides G, Almeida JP, Babbage AK, Bagguley CL, Bailey J, Barlow KF, Bates KN, Beard LM, Beare DM, Beasley OP, Bird CP, Blakey SE, Bridgeman AM, Brown AJ, Buck D, Burrill W, Butler AP, Carder C, Carter NP, Chapman JC, Clamp M, Clark G, Clark LN, Clark SY, Clee CM, Clegg S, Cobley VE, Collier RE, Connor R, Corby NR, Coulson A, Coville GJ, Deadman R, Dhami P, Dunn M, Ellington AG, Frankland JA, Fraser A, French L, Garner P, Grafham DV, Griffiths C, Griffiths MN, Gwilliam R, Hall RE, Hammond S, Harley JL, Heath PD, Ho S, Holden JL, Howden PJ, Huckle E, Hunt AR, Hunt SE, Jekosch K, Johnson CM, Johnson D, Kay MP, Kimberley AM, King A, Knights A, Laird GK, Lawlor S, Lehvaslaiho MH, Leversha M, Lloyd C, Lloyd DM, Lovell JD, Marsh VL, Martin SL, McConnachie LJ, McLay K, McMurray AA, Milne S, Mistry D, Moore MJ, Mullikin JC, Nickerson T, Oliver K, Parker A, Patel R, Pearce TA, Peck AI, Phillimore BJ, Prathalingam SR, Plumb RW, Ramsay H, Rice CM, Ross MT, Scott CE, Sehra HK, Shownkeen R, Sims S, Skuce CD, Smith ML, Soderlund C, Steward CA, Sulston JE, Swann M, Sycamore N, Taylor R, Tee L, Thomas DW, Thorpe A, Tracey A, Tromans AC, Vaudin M, Wall M, Wallis JM, Whitehead SL, Whittaker P, Willey DL, Williams L, Williams SA, Wilming L, Wray PW, Hubbard T, Durbin RM, Bentley DR, Beck S, Rogers J
Nature414(6866)865-71(2001 Dec 20-27)
Conserved linkage of NK-2 homeobox gene pairs Nkx2-2/2-4 and Nkx2-1/2-9 in mammals.
Wang CC, Brodnicki T, Copeland NG, Jenkins NA, Harvey RP
Mammalian genome : official journal of the International Mammalian Genome Society11(6)466-8(2000 Jun)
Regional expression of the homeobox gene Nkx-2.2 in the developing mammalian forebrain.
Price M, Lazzaro D, Pohl T, Mattei MG, R?ther U, Olivo JC, Duboule D, Di Lauro R
Neuron8(2)241-55(1992 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following NKX2-4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the NKX2-4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu00202 | |
Clone ID Related Accession (Same CDS sequence) | NM_033176.1 , NM_033176.2 | |
Accession Version | NM_033176.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1065bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Homo sapiens(human) | |
Product | homeobox protein Nkx-2.4 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL158013.25. On or before Sep 23, 2007 this sequence version replaced XM_927653.2, XM_940179.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. |
1 | ATGTCGTTGA GCCCAAAGCA CACGACGCCC TTCTCCGTGT CCGACATCCT GAGCCCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_149416.1 |
CDS | 11..1075 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTCGTTGA GCCCAAAGCA CACGACGCCC TTCTCCGTGT CCGACATCCT GAGCCCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu00202 | |
Clone ID Related Accession (Same CDS sequence) | NM_033176.1 , NM_033176.2 | |
Accession Version | NM_033176.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1065bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-21 | |
Organism | Homo sapiens(human) | |
Product | homeobox protein Nkx-2.4 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL158013.25. On Nov 22, 2018 this sequence version replaced NM_033176.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000351817.5/ ENSP00000345147.4 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGTCGTTGA GCCCAAAGCA CACGACGCCC TTCTCCGTGT CCGACATCCT GAGCCCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_149416.1 |
CDS | 128..1192 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGTCGTTGA GCCCAAAGCA CACGACGCCC TTCTCCGTGT CCGACATCCT GAGCCCCATC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Lupus nephritis susceptibility loci in women with systemic lupus erythematosus. |
A census of human transcription factors: function, expression and evolution. |
The DNA sequence and comparative analysis of human chromosome 20. |
Conserved linkage of NK-2 homeobox gene pairs Nkx2-2/2-4 and Nkx2-1/2-9 in mammals. |
Regional expression of the homeobox gene Nkx-2.2 in the developing mammalian forebrain. |