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SLC2A11 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol SLC2A11
Entrez Gene ID 66035
Full Name solute carrier family 2 member 11
Synonyms GLUT10,GLUT11
General protein information
Preferred Names

solute carrier family 2 member 11

Names

solute carrier family 2, facilitated glucose transporter member 11
facilitative glucose transporter GLUT11
glucose transporter protein 10
glucose transporter protein 11
glucose transporter type 10
glucose transporter type 11
glucose transporter-like protein XI
solute carrier family 2 (facilitated glucose transporter), member 11

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

22

22q11.23

Summary This gene belongs to a family of proteins that mediate the transport of sugars across the cell membrane. The encoded protein transports glucose and fructose. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2013].
Disorder MIM:

610367


mRNA and Protein(s)

mRNA Protein Name
NM_001024938.3 NP_001020109.1 solute carrier family 2, facilitated glucose transporter member 11 isoform c
NM_001024939.3 NP_001020110.1 solute carrier family 2, facilitated glucose transporter member 11 isoform b
NM_001282864.1 NP_001269793.1 solute carrier family 2, facilitated glucose transporter member 11 isoform d
NM_030807.4 NP_110434.3 solute carrier family 2, facilitated glucose transporter member 11 isoform a



Xenopus tropicalis (tropical clawed frog) slc2a11 XP_004910639.1
Macaca mulatta (rhesus monkey) SLC2A11 XP_001086712.1
Homo sapiens (human) SLC2A11 NP_110434.3
Bos taurus (cattle) SLC2A11 NP_001180026.1
Gallus gallus (chicken) SLC2A11 XP_425279.2
Pan troglodytes (chimpanzee) SLC2A11 XP_003317186.1
Canis lupus familiaris (dog) SLC2A11 XP_543531.4
Danio rerio (zebrafish) LOC560358 XP_688856.2


Related articles in PubMed

Multiple myeloma exhibits novel dependence on GLUT4, GLUT8, and GLUT11: implications for glucose transporter-directed therapy.
McBrayer SK, Cheng JC, Singhal S, Krett NL, Rosen ST, Shanmugam M
Blood119(20)4686-97(2012 May)

A highly conserved hydrophobic motif in the exofacial vestibule of fructose transporting SLC2A proteins acts as a critical determinant of their substrate selectivity.
Manolescu AR, Augustin R, Moley K, Cheeseman C
Molecular membrane biology24(5-6)455-63(2007 Sep-Dec)

Characterization of the human SLC2A11 (GLUT11) gene: alternative promoter usage, function, expression, and subcellular distribution of three isoforms, and lack of mouse orthologue.
Scheepers A, Schmidt S, Manolescu A, Cheeseman CI, Bell A, Zahn C, Joost HG, Schürmann A
Molecular membrane biology22(4)339-51(2005 Jul-Aug)

GLUT11, but not GLUT8 or GLUT12, is expressed in human skeletal muscle in a fibre type-specific pattern.
Gaster M, Handberg A, Schürmann A, Joost HG, Beck-Nielsen H, Schrøder HD
Pflugers Archiv : European journal of physiology448(1)105-13(2004 Apr)

Cloning and characterization of glucose transporter 11, a novel sugar transporter that is alternatively spliced in various tissues.
Wu X, Li W, Sharma V, Godzik A, Freeze HH
Molecular genetics and metabolism76(1)37-45(2002 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Critical roles for novel GLUT family members highlight a therapeutic strategy entailing selective GLUT inhibition to specifically target aberrant glucose metabolism in cancer.
Title: Multiple myeloma exhibits novel dependence on GLUT4, GLUT8, and GLUT11: implications for glucose transporter-directed therapy.

Observational study of gene-disease association and gene-gene interaction. (HuGE Navigator)
Title: Polymorphisms in innate immunity genes and risk of childhood leukemia.

Observational study of gene-disease association. (HuGE Navigator)
Title: Risk of meningioma and common variation in genes related to innate immunity.

Observational study of gene-disease association. (HuGE Navigator)
Title: Common variation in genes related to innate immunity and risk of adult glioma.

GLUT11 can also transport fructose, but it has the motif DSV at the same position, which appears to function in the same manner as NXI and when all three residues are replaced with NAV fructose transport lost.
Title: A highly conserved hydrophobic motif in the exofacial vestibule of fructose transporting SLC2A proteins acts as a critical determinant of their substrate selectivity.

The following SLC2A11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC2A11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu00721 NM_001024939.3
Latest version!
Homo sapiens solute carrier family 2 member 11 (SLC2A11), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00
OHu07871 NM_030807.4
Latest version!
Homo sapiens solute carrier family 2 member 11 (SLC2A11), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
OHu08461 NM_001282864.1
Latest version!
Homo sapiens solute carrier family 2 member 11 (SLC2A11), transcript variant 4, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $307.30
$439.00
OHu08722 NM_001024938.3
Latest version!
Homo sapiens solute carrier family 2 member 11 (SLC2A11), transcript variant 3, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $223.30
$319.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu00721
Clone ID Related Accession (Same CDS sequence) NM_001024939.3
Accession Version NM_001024939.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1500bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-02-20
Organism Homo sapiens(Human)
Product solute carrier family 2, facilitated glucose transporter member 11 isoform b
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DC303452.1, AP000350.1 and AK092466.1. On Sep 20, 2013 this sequence version replaced NM_001024939.2. Transcript Variant: This variant (2, also known as SLC2A11-c) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (b) is shorter and has a distinct N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: CR456373.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGCTCCACG CCCTCCTGCG ATCTAGAATG ATTCAGGGCA GGATCCTGCT CCTGACCATC 
TGCGCTGCCG GCATTGGTGG GACTTTTCAG TTTGGCTATA ACCTCTCTAT CATCAATGCC
CCGACCTTGC ACATTCAGGA ATTCACCAAT GAGACATGGC AGGCGCGTAC TGGAGAGCCA
CTGCCCGATC ACCTAGTCCT GCTTATGTGG TCCCTCATCG TGTCTCTGTA TCCCCTGGGA
GGCCTCTTTG GAGCACTGCT TGCAGGTCCC TTGGCCATCA CGCTGGGAAG GAAGAAGTCC
CTCCTGGTGA ATAACATCTT TGTGGTGTCA GCAGCAATCC TGTTTGGATT CAGCCGCAAA
GCAGGCTCCT TTGAGATGAT CATGCTGGGA AGACTGCTCG TGGGAGTCAA TGCAGGTGTG
AGCATGAACA TCCAGCCCAT GTACCTGGGG GAGAGCGCCC CTAAGGAGCT CCGAGGAGCT
GTGGCCATGA GCTCAGCCAT CTTTACGGCT CTGGGGATCG TGATGGGACA GGTGGTCGGA
CTCAGGGAGC TCCTAGGTGG CCCTCAGGCC TGGCCCCTGC TGCTGGCCAG CTGCCTGGTG
CCCGGGGCGC TCCAGCTCGC CTCCCTGCCT CTGCTCCCTG AAAGCCCGCG CTACCTCCTC
ATTGACTGTG GAGACACCGA GGCCTGCCTG GCAGCACTAC GGCGGCTCCG GGGCTCCGGG
GACTTGGCAG GGGAGCTGGA GGAGCTGGAG GAGGAGCGCG CTGCCTGCCA GGGCTGCCGT
GCCCGGCGCC CATGGGAGCT GTTCCAGCAT CGGGCCCTGA GGAGACAGGT GACAAGCCTC
GTGGTTCTGG GCAGTGCCAT GGAGCTCTGC GGGAATGACT CGGTGTACGC CTACGCCTCC
TCCGTGTTCC GGAAGGCAGG AGTGCCGGAA GCGAAGATCC AGTACGCGAT CATCGGGACT
GGGAGCTGCG AGCTGCTCAC GGCGGTTGTT AGTTGTGTGG TAATCGAGAG GGTGGGTCGG
CGCGTGCTGC TCATCGGTGG GTACAGCCTG ATGACCTGCT GGGGGAGCAT CTTCACTGTG
GCCCTGTGCC TGCAGAGCTC CTTCCCCTGG ACACTCTACC TGGCCATGGC CTGCATCTTT
GCCTTCATCC TCAGCTTTGG CATTGGCCCT GCCGGAGTGA CGGGGATCCT GGCCACAGAG
CTGTTTGACC AGATGGCCAG GCCTGCTGCC TGCATGGTCT GCGGGGCGCT CATGTGGATC
ATGCTCATCC TGGTCGGCCT GGGATTTCCC TTTATCATGG AGGCCTTGTC CCACTTCCTC
TATGTCCCTT TCCTTGGTGT CTGTGTCTGT GGGGCCATCT ACACTGGCCT GTTCCTTCCT
GAGACCAAAG GCAAGACCTT CCAAGAGATC TCCAAGGAAT TACACAGACT CAACTTCCCC
AGGCGGGCCC AGGGCCCCAC GTGGAGGAGC CTGGAGGTTA TCCAGTCAAC AGAACTCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001020110.1
CDS148..1647
Exon (1)1..177
Translation

Target ORF information:

RefSeq Version NM_001024939.3
Organism Homo sapiens(Human)
Definition Homo sapiens solute carrier family 2 member 11 (SLC2A11), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001024939.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGCTCCACG CCCTCCTGCG ATCTAGAATG ATTCAGGGCA GGATCCTGCT CCTGACCATC 
TGCGCTGCCG GCATTGGTGG GACTTTTCAG TTTGGCTATA ACCTCTCTAT CATCAATGCC
CCGACCTTGC ACATTCAGGA ATTCACCAAT GAGACATGGC AGGCGCGTAC TGGAGAGCCA
CTGCCCGATC ACCTAGTCCT GCTTATGTGG TCCCTCATCG TGTCTCTGTA TCCCCTGGGA
GGCCTCTTTG GAGCACTGCT TGCAGGTCCC TTGGCCATCA CGCTGGGAAG GAAGAAGTCC
CTCCTGGTGA ATAACATCTT TGTGGTGTCA GCAGCAATCC TGTTTGGATT CAGCCGCAAA
GCAGGCTCCT TTGAGATGAT CATGCTGGGA AGACTGCTCG TGGGAGTCAA TGCAGGTGTG
AGCATGAACA TCCAGCCCAT GTACCTGGGG GAGAGCGCCC CTAAGGAGCT CCGAGGAGCT
GTGGCCATGA GCTCAGCCAT CTTTACGGCT CTGGGGATCG TGATGGGACA GGTGGTCGGA
CTCAGGGAGC TCCTAGGTGG CCCTCAGGCC TGGCCCCTGC TGCTGGCCAG CTGCCTGGTG
CCCGGGGCGC TCCAGCTCGC CTCCCTGCCT CTGCTCCCTG AAAGCCCGCG CTACCTCCTC
ATTGACTGTG GAGACACCGA GGCCTGCCTG GCAGCACTAC GGCGGCTCCG GGGCTCCGGG
GACTTGGCAG GGGAGCTGGA GGAGCTGGAG GAGGAGCGCG CTGCCTGCCA GGGCTGCCGT
GCCCGGCGCC CATGGGAGCT GTTCCAGCAT CGGGCCCTGA GGAGACAGGT GACAAGCCTC
GTGGTTCTGG GCAGTGCCAT GGAGCTCTGC GGGAATGACT CGGTGTACGC CTACGCCTCC
TCCGTGTTCC GGAAGGCAGG AGTGCCGGAA GCGAAGATCC AGTACGCGAT CATCGGGACT
GGGAGCTGCG AGCTGCTCAC GGCGGTTGTT AGTTGTGTGG TAATCGAGAG GGTGGGTCGG
CGCGTGCTGC TCATCGGTGG GTACAGCCTG ATGACCTGCT GGGGGAGCAT CTTCACTGTG
GCCCTGTGCC TGCAGAGCTC CTTCCCCTGG ACACTCTACC TGGCCATGGC CTGCATCTTT
GCCTTCATCC TCAGCTTTGG CATTGGCCCT GCCGGAGTGA CGGGGATCCT GGCCACAGAG
CTGTTTGACC AGATGGCCAG GCCTGCTGCC TGCATGGTCT GCGGGGCGCT CATGTGGATC
ATGCTCATCC TGGTCGGCCT GGGATTTCCC TTTATCATGG AGGCCTTGTC CCACTTCCTC
TATGTCCCTT TCCTTGGTGT CTGTGTCTGT GGGGCCATCT ACACTGGCCT GTTCCTTCCT
GAGACCAAAG GCAAGACCTT CCAAGAGATC TCCAAGGAAT TACACAGACT CAACTTCCCC
AGGCGGGCCC AGGGCCCCAC GTGGAGGAGC CTGGAGGTTA TCCAGTCAAC AGAACTCTAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu07871
Clone ID Related Accession (Same CDS sequence) NM_030807.4
Accession Version NM_030807.4 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1512bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-02-20
Organism Homo sapiens(Human)
Product solute carrier family 2, facilitated glucose transporter member 11 isoform a
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA084206.1, AK314502.1, AJ271290.1, AK092466.1 and AP000350.1. On Sep 20, 2013 this sequence version replaced NM_030807.3. Transcript Variant: This variant (1, also known as SLC2A11-b) encodes isoform a (also known as GLUT11-L). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AF443201.1, AK314502.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1970526, SAMEA2149398 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGAGGATG AACTGGAGCC GTCCTTACGG CCTCGGACGC AGATTCAGGG CAGGATCCTG 
CTCCTGACCA TCTGCGCTGC CGGCATTGGT GGGACTTTTC AGTTTGGCTA TAACCTCTCT
ATCATCAATG CCCCGACCTT GCACATTCAG GAATTCACCA ATGAGACATG GCAGGCGCGT
ACTGGAGAGC CACTGCCCGA TCACCTAGTC CTGCTTATGT GGTCCCTCAT CGTGTCTCTG
TATCCCCTGG GAGGCCTCTT TGGAGCACTG CTTGCAGGTC CCTTGGCCAT CACGCTGGGA
AGGAAGAAGT CCCTCCTGGT GAATAACATC TTTGTGGTGT CAGCAGCAAT CCTGTTTGGA
TTCAGCCGCA AAGCAGGCTC CTTTGAGATG ATCATGCTGG GAAGACTGCT CGTGGGAGTC
AATGCAGGTG TGAGCATGAA CATCCAGCCC ATGTACCTGG GGGAGAGCGC CCCTAAGGAG
CTCCGAGGAG CTGTGGCCAT GAGCTCAGCC ATCTTTACGG CTCTGGGGAT CGTGATGGGA
CAGGTGGTCG GACTCAGGGA GCTCCTAGGT GGCCCTCAGG CCTGGCCCCT GCTGCTGGCC
AGCTGCCTGG TGCCCGGGGC GCTCCAGCTC GCCTCCCTGC CTCTGCTCCC TGAAAGCCCG
CGCTACCTCC TCATTGACTG TGGAGACACC GAGGCCTGCC TGGCAGCACT ACGGCGGCTC
CGGGGCTCCG GGGACTTGGC AGGGGAGCTG GAGGAGCTGG AGGAGGAGCG CGCTGCCTGC
CAGGGCTGCC GTGCCCGGCG CCCATGGGAG CTGTTCCAGC ATCGGGCCCT GAGGAGACAG
GTGACAAGCC TCGTGGTTCT GGGCAGTGCC ATGGAGCTCT GCGGGAATGA CTCGGTGTAC
GCCTACGCCT CCTCCGTGTT CCGGAAGGCA GGAGTGCCGG AAGCGAAGAT CCAGTACGCG
ATCATCGGGA CTGGGAGCTG CGAGCTGCTC ACGGCGGTTG TTAGTTGTGT GGTAATCGAG
AGGGTGGGTC GGCGCGTGCT GCTCATCGGT GGGTACAGCC TGATGACCTG CTGGGGGAGC
ATCTTCACTG TGGCCCTGTG CCTGCAGAGC TCCTTCCCCT GGACACTCTA CCTGGCCATG
GCCTGCATCT TTGCCTTCAT CCTCAGCTTT GGCATTGGCC CTGCCGGAGT GACGGGGATC
CTGGCCACAG AGCTGTTTGA CCAGATGGCC AGGCCTGCTG CCTGCATGGT CTGCGGGGCG
CTCATGTGGA TCATGCTCAT CCTGGTCGGC CTGGGATTTC CCTTTATCAT GGAGGCCTTG
TCCCACTTCC TCTATGTCCC TTTCCTTGGT GTCTGTGTCT GTGGGGCCAT CTACACTGGC
CTGTTCCTTC CTGAGACCAA AGGCAAGACC TTCCAAGAGA TCTCCAAGGA ATTACACAGA
CTCAACTTCC CCAGGCGGGC CCAGGGCCCC ACGTGGAGGA GCCTGGAGGT TATCCAGTCA
ACAGAACTCT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_110434.3
CDS359..1870
Misc Feature(1)314..316
Exon (1)1..289
Exon (2)290..400
Translation

Target ORF information:

RefSeq Version NM_030807.4
Organism Homo sapiens(Human)
Definition Homo sapiens solute carrier family 2 member 11 (SLC2A11), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_030807.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
ATGGAGGATG AACTGGAGCC GTCCTTACGG CCTCGGACGC AGATTCAGGG CAGGATCCTG 
CTCCTGACCA TCTGCGCTGC CGGCATTGGT GGGACTTTTC AGTTTGGCTA TAACCTCTCT
ATCATCAATG CCCCGACCTT GCACATTCAG GAATTCACCA ATGAGACATG GCAGGCGCGT
ACTGGAGAGC CACTGCCCGA TCACCTAGTC CTGCTTATGT GGTCCCTCAT CGTGTCTCTG
TATCCCCTGG GAGGCCTCTT TGGAGCACTG CTTGCAGGTC CCTTGGCCAT CACGCTGGGA
AGGAAGAAGT CCCTCCTGGT GAATAACATC TTTGTGGTGT CAGCAGCAAT CCTGTTTGGA
TTCAGCCGCA AAGCAGGCTC CTTTGAGATG ATCATGCTGG GAAGACTGCT CGTGGGAGTC
AATGCAGGTG TGAGCATGAA CATCCAGCCC ATGTACCTGG GGGAGAGCGC CCCTAAGGAG
CTCCGAGGAG CTGTGGCCAT GAGCTCAGCC ATCTTTACGG CTCTGGGGAT CGTGATGGGA
CAGGTGGTCG GACTCAGGGA GCTCCTAGGT GGCCCTCAGG CCTGGCCCCT GCTGCTGGCC
AGCTGCCTGG TGCCCGGGGC GCTCCAGCTC GCCTCCCTGC CTCTGCTCCC TGAAAGCCCG
CGCTACCTCC TCATTGACTG TGGAGACACC GAGGCCTGCC TGGCAGCACT ACGGCGGCTC
CGGGGCTCCG GGGACTTGGC AGGGGAGCTG GAGGAGCTGG AGGAGGAGCG CGCTGCCTGC
CAGGGCTGCC GTGCCCGGCG CCCATGGGAG CTGTTCCAGC ATCGGGCCCT GAGGAGACAG
GTGACAAGCC TCGTGGTTCT GGGCAGTGCC ATGGAGCTCT GCGGGAATGA CTCGGTGTAC
GCCTACGCCT CCTCCGTGTT CCGGAAGGCA GGAGTGCCGG AAGCGAAGAT CCAGTACGCG
ATCATCGGGA CTGGGAGCTG CGAGCTGCTC ACGGCGGTTG TTAGTTGTGT GGTAATCGAG
AGGGTGGGTC GGCGCGTGCT GCTCATCGGT GGGTACAGCC TGATGACCTG CTGGGGGAGC
ATCTTCACTG TGGCCCTGTG CCTGCAGAGC TCCTTCCCCT GGACACTCTA CCTGGCCATG
GCCTGCATCT TTGCCTTCAT CCTCAGCTTT GGCATTGGCC CTGCCGGAGT GACGGGGATC
CTGGCCACAG AGCTGTTTGA CCAGATGGCC AGGCCTGCTG CCTGCATGGT CTGCGGGGCG
CTCATGTGGA TCATGCTCAT CCTGGTCGGC CTGGGATTTC CCTTTATCAT GGAGGCCTTG
TCCCACTTCC TCTATGTCCC TTTCCTTGGT GTCTGTGTCT GTGGGGCCAT CTACACTGGC
CTGTTCCTTC CTGAGACCAA AGGCAAGACC TTCCAAGAGA TCTCCAAGGA ATTACACAGA
CTCAACTTCC CCAGGCGGGC CCAGGGCCCC ACGTGGAGGA GCCTGGAGGT TATCCAGTCA
ACAGAACTCT AG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu08461
Clone ID Related Accession (Same CDS sequence) NM_001282864.1
Accession Version NM_001282864.1 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1608bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-13
Organism Homo sapiens(Human)
Product solute carrier family 2, facilitated glucose transporter member 11 isoform d
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from AP000350.1, AK300196.1 and AK092466.1. Transcript Variant: This variant (4) differs in the 5' UTR and contains multiple differences in the coding region, compared to variant 1, one of which results in a frameshift. The encoded isoform (d) is longer and has a distinct C- terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK300196.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN04284274 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGAGGATG AACTGGAGCC GTCCTTACGG CCTCGGACGC AGATTCAGGG CAGGATCCTG 
CTCCTGACCA TCTGCGCTGC CGGCATTGGT GGGACTTTTC AGTTTGGCTA TAACCTCTCT
ATCATCAATG CCCCGACCTT GCACATTCAG GAATTCACCA ATGAGACATG GCAGGCGCGT
ACTGGAGAGC CACTGCCCGA TCACCTAGTC CTGCTTATGT GGTCCCTCAT CGTGTCTCTG
TATCCCCTGG GAGGCCTCTT TGGAGCACTG CTTGCAGGTC CCTTGGCCAT CACGCTGGGA
AGGAAGAAGT CCCTCCTGGT GAATAACATC TTTGTGGTGT CAGCAGCAAT CCTGTTTGGA
TTCAGCCGCA AAGCAGGCTC CTTTGAGATG ATCATGCTGG GAAGACTGCT CGTGGGAGTC
AATGCAGGTG TGAGCATGAA CATCCAGCCC ATGTACCTGG GGGAGAGCGC CCCTAAGGAG
CTCCGAGGAG CTGTGGCCAT GAGCTCAGCC ATCTTTACGG CTCTGGGGAT CGTGATGGGA
CAGGTGGTCG GACTCAGGGA GCTCCTAGGT GGCCCTCAGG CCTGGCCCCT GCTGCTGGCC
AGCTGCCTGG TGCCCGGGGC GCTCCAGCTC GCCTCCCTGC CTCTGCTCCC TGAAAGCCCG
CGCTACCTCC TCATTGACTG TGGAGACACC GAGGCCTGCC TGGCAGCACT ACGGCGGCTC
CGGGGCTCCG GGGACTTGGC AGGGGAGCTG GAGGAGCTGG AGGAGGAGCG CGCTGCCTGC
CAGGGCTGCC GTGCCCGGCG CCCATGGGAG CTGTTCCAGC ATCGGGCCCT GAGGAGACAG
GTGACAAGCC TCGTGGTTCT GGGCAGTGCC ATGGAGCTCT GCGGGAATGA CTCGGTGTAC
GCCTACGCCT CCTCCGTGTT CCGGAAGGCA GGAGTGCCGG AAGCGAAGAT CCAGTACGCG
ATCATCGGGA CTGGGAGCTG CGAGCTGCTC ACGGCGGTTG TTAGTGTAGC TGGGGTGGAT
GAGGGCTGGG GGGTCCAGGC CGGGCTGACT TCCACCTCAC CCCCGCCCCG TCCACGGCAG
AGCTCCTTCC CCTGGACACT CTACCTGGCC ATGGCCTGCA TCTTTGCCTT CATCCTCAGC
TTTGGCATTG GCCCTGCCGG AGTGACGGGG ATCCTGGCCA CAGAGCTGTT TGACCAGATG
GCCAGGCCTG CTGCCTGCAT GGTCTGCGGG GCGCTCATGT GGATCATGCT CATCCTGGTC
GGCCTGGGAT TTCCCTTTAT CATGGTCTTG GGGTCTTTTT TAATCCGCAG GAGGCCTTGT
CCCACTTCCT CTATGTCCCT TTCCTTGGTG TCTGTGTCTG TGGGGCCATC TACACTGGCC
TGTTCCTTCC TGAGACCAAA GGCAAGACCT TCCAAGAGAT CTCCAAGGAA TTACACAGAC
TCAACTTCCC CAGGCGGGCC CAGGGCCCCA CGTGGAGGAG CCTGGAGGTT ATCCAGTCAA
CAGAACTCTA GTCCCAAAGG GGTGGCCAGA GCCAAAGCCA GCTACTGTCC TGTCCTCTGC
TTCCTGCCAG GGCCCTGGTC CTCACTCCCT CCTGCATTCC TCATTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001269793.1
CDS491..2098
Misc Feature(1)446..448
Misc Feature(2)554..1774
Misc Feature(3)692..>1141
Exon (1)1..532
Exon (2)533..631
Exon (3)632..792
Exon (4)793..917
Exon (5)918..1047
Exon (6)1048..1196
Exon (7)1197..1384
Exon (8)1385..1495
Exon (9)1496..1646
Exon (10)1647..1774
Exon (11)1775..3264
Translation

Target ORF information:

RefSeq Version NM_001282864.1
Organism Homo sapiens(Human)
Definition Homo sapiens solute carrier family 2 member 11 (SLC2A11), transcript variant 4, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001282864.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
ATGGAGGATG AACTGGAGCC GTCCTTACGG CCTCGGACGC AGATTCAGGG CAGGATCCTG 
CTCCTGACCA TCTGCGCTGC CGGCATTGGT GGGACTTTTC AGTTTGGCTA TAACCTCTCT
ATCATCAATG CCCCGACCTT GCACATTCAG GAATTCACCA ATGAGACATG GCAGGCGCGT
ACTGGAGAGC CACTGCCCGA TCACCTAGTC CTGCTTATGT GGTCCCTCAT CGTGTCTCTG
TATCCCCTGG GAGGCCTCTT TGGAGCACTG CTTGCAGGTC CCTTGGCCAT CACGCTGGGA
AGGAAGAAGT CCCTCCTGGT GAATAACATC TTTGTGGTGT CAGCAGCAAT CCTGTTTGGA
TTCAGCCGCA AAGCAGGCTC CTTTGAGATG ATCATGCTGG GAAGACTGCT CGTGGGAGTC
AATGCAGGTG TGAGCATGAA CATCCAGCCC ATGTACCTGG GGGAGAGCGC CCCTAAGGAG
CTCCGAGGAG CTGTGGCCAT GAGCTCAGCC ATCTTTACGG CTCTGGGGAT CGTGATGGGA
CAGGTGGTCG GACTCAGGGA GCTCCTAGGT GGCCCTCAGG CCTGGCCCCT GCTGCTGGCC
AGCTGCCTGG TGCCCGGGGC GCTCCAGCTC GCCTCCCTGC CTCTGCTCCC TGAAAGCCCG
CGCTACCTCC TCATTGACTG TGGAGACACC GAGGCCTGCC TGGCAGCACT ACGGCGGCTC
CGGGGCTCCG GGGACTTGGC AGGGGAGCTG GAGGAGCTGG AGGAGGAGCG CGCTGCCTGC
CAGGGCTGCC GTGCCCGGCG CCCATGGGAG CTGTTCCAGC ATCGGGCCCT GAGGAGACAG
GTGACAAGCC TCGTGGTTCT GGGCAGTGCC ATGGAGCTCT GCGGGAATGA CTCGGTGTAC
GCCTACGCCT CCTCCGTGTT CCGGAAGGCA GGAGTGCCGG AAGCGAAGAT CCAGTACGCG
ATCATCGGGA CTGGGAGCTG CGAGCTGCTC ACGGCGGTTG TTAGTGTAGC TGGGGTGGAT
GAGGGCTGGG GGGTCCAGGC CGGGCTGACT TCCACCTCAC CCCCGCCCCG TCCACGGCAG
AGCTCCTTCC CCTGGACACT CTACCTGGCC ATGGCCTGCA TCTTTGCCTT CATCCTCAGC
TTTGGCATTG GCCCTGCCGG AGTGACGGGG ATCCTGGCCA CAGAGCTGTT TGACCAGATG
GCCAGGCCTG CTGCCTGCAT GGTCTGCGGG GCGCTCATGT GGATCATGCT CATCCTGGTC
GGCCTGGGAT TTCCCTTTAT CATGGTCTTG GGGTCTTTTT TAATCCGCAG GAGGCCTTGT
CCCACTTCCT CTATGTCCCT TTCCTTGGTG TCTGTGTCTG TGGGGCCATC TACACTGGCC
TGTTCCTTCC TGAGACCAAA GGCAAGACCT TCCAAGAGAT CTCCAAGGAA TTACACAGAC
TCAACTTCCC CAGGCGGGCC CAGGGCCCCA CGTGGAGGAG CCTGGAGGTT ATCCAGTCAA
CAGAACTCTA GTCCCAAAGG GGTGGCCAGA GCCAAAGCCA GCTACTGTCC TGTCCTCTGC
TTCCTGCCAG GGCCCTGGTC CTCACTCCCT CCTGCATTCC TCATTTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu08722
Clone ID Related Accession (Same CDS sequence) NM_001024938.3
Accession Version NM_001024938.3 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 1491bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-02-20
Organism Homo sapiens(Human)
Product solute carrier family 2, facilitated glucose transporter member 11 isoform c
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA084206.1, AK075467.1, BC018967.2 and AP000350.1. On Sep 20, 2013 this sequence version replaced NM_001024938.2. Transcript Variant: This variant (3, also known as SLC2A11-a) differs in the 5' UTR, lacks a portion of the 5' coding region, and initiates translation at an alternate upstream start codon, compared to variant 1. The encoded isoform (c, also known as GLUT11-S) is shorter and has a distinct N-terminus, compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AK075467.1, AJ271290.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968968 [ECO:0000348] ##Evidence-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGAGAGCGC TCCGAAGACT GATTCAGGGC AGGATCCTGC TCCTGACCAT CTGCGCTGCC 
GGCATTGGTG GGACTTTTCA GTTTGGCTAT AACCTCTCTA TCATCAATGC CCCGACCTTG
CACATTCAGG AATTCACCAA TGAGACATGG CAGGCGCGTA CTGGAGAGCC ACTGCCCGAT
CACCTAGTCC TGCTTATGTG GTCCCTCATC GTGTCTCTGT ATCCCCTGGG AGGCCTCTTT
GGAGCACTGC TTGCAGGTCC CTTGGCCATC ACGCTGGGAA GGAAGAAGTC CCTCCTGGTG
AATAACATCT TTGTGGTGTC AGCAGCAATC CTGTTTGGAT TCAGCCGCAA AGCAGGCTCC
TTTGAGATGA TCATGCTGGG AAGACTGCTC GTGGGAGTCA ATGCAGGTGT GAGCATGAAC
ATCCAGCCCA TGTACCTGGG GGAGAGCGCC CCTAAGGAGC TCCGAGGAGC TGTGGCCATG
AGCTCAGCCA TCTTTACGGC TCTGGGGATC GTGATGGGAC AGGTGGTCGG ACTCAGGGAG
CTCCTAGGTG GCCCTCAGGC CTGGCCCCTG CTGCTGGCCA GCTGCCTGGT GCCCGGGGCG
CTCCAGCTCG CCTCCCTGCC TCTGCTCCCT GAAAGCCCGC GCTACCTCCT CATTGACTGT
GGAGACACCG AGGCCTGCCT GGCAGCACTA CGGCGGCTCC GGGGCTCCGG GGACTTGGCA
GGGGAGCTGG AGGAGCTGGA GGAGGAGCGC GCTGCCTGCC AGGGCTGCCG TGCCCGGCGC
CCATGGGAGC TGTTCCAGCA TCGGGCCCTG AGGAGACAGG TGACAAGCCT CGTGGTTCTG
GGCAGTGCCA TGGAGCTCTG CGGGAATGAC TCGGTGTACG CCTACGCCTC CTCCGTGTTC
CGGAAGGCAG GAGTGCCGGA AGCGAAGATC CAGTACGCGA TCATCGGGAC TGGGAGCTGC
GAGCTGCTCA CGGCGGTTGT TAGTTGTGTG GTAATCGAGA GGGTGGGTCG GCGCGTGCTG
CTCATCGGTG GGTACAGCCT GATGACCTGC TGGGGGAGCA TCTTCACTGT GGCCCTGTGC
CTGCAGAGCT CCTTCCCCTG GACACTCTAC CTGGCCATGG CCTGCATCTT TGCCTTCATC
CTCAGCTTTG GCATTGGCCC TGCCGGAGTG ACGGGGATCC TGGCCACAGA GCTGTTTGAC
CAGATGGCCA GGCCTGCTGC CTGCATGGTC TGCGGGGCGC TCATGTGGAT CATGCTCATC
CTGGTCGGCC TGGGATTTCC CTTTATCATG GAGGCCTTGT CCCACTTCCT CTATGTCCCT
TTCCTTGGTG TCTGTGTCTG TGGGGCCATC TACACTGGCC TGTTCCTTCC TGAGACCAAA
GGCAAGACCT TCCAAGAGAT CTCCAAGGAA TTACACAGAC TCAACTTCCC CAGGCGGGCC
CAGGGCCCCA CGTGGAGGAG CCTGGAGGTT ATCCAGTCAA CAGAACTCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001020109.1
CDS269..1759
Misc Feature(1)89..91
Exon (1)1..289
Translation

Target ORF information:

RefSeq Version NM_001024938.3
Organism Homo sapiens(Human)
Definition Homo sapiens solute carrier family 2 member 11 (SLC2A11), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_001024938.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
ATGAGAGCGC TCCGAAGACT GATTCAGGGC AGGATCCTGC TCCTGACCAT CTGCGCTGCC 
GGCATTGGTG GGACTTTTCA GTTTGGCTAT AACCTCTCTA TCATCAATGC CCCGACCTTG
CACATTCAGG AATTCACCAA TGAGACATGG CAGGCGCGTA CTGGAGAGCC ACTGCCCGAT
CACCTAGTCC TGCTTATGTG GTCCCTCATC GTGTCTCTGT ATCCCCTGGG AGGCCTCTTT
GGAGCACTGC TTGCAGGTCC CTTGGCCATC ACGCTGGGAA GGAAGAAGTC CCTCCTGGTG
AATAACATCT TTGTGGTGTC AGCAGCAATC CTGTTTGGAT TCAGCCGCAA AGCAGGCTCC
TTTGAGATGA TCATGCTGGG AAGACTGCTC GTGGGAGTCA ATGCAGGTGT GAGCATGAAC
ATCCAGCCCA TGTACCTGGG GGAGAGCGCC CCTAAGGAGC TCCGAGGAGC TGTGGCCATG
AGCTCAGCCA TCTTTACGGC TCTGGGGATC GTGATGGGAC AGGTGGTCGG ACTCAGGGAG
CTCCTAGGTG GCCCTCAGGC CTGGCCCCTG CTGCTGGCCA GCTGCCTGGT GCCCGGGGCG
CTCCAGCTCG CCTCCCTGCC TCTGCTCCCT GAAAGCCCGC GCTACCTCCT CATTGACTGT
GGAGACACCG AGGCCTGCCT GGCAGCACTA CGGCGGCTCC GGGGCTCCGG GGACTTGGCA
GGGGAGCTGG AGGAGCTGGA GGAGGAGCGC GCTGCCTGCC AGGGCTGCCG TGCCCGGCGC
CCATGGGAGC TGTTCCAGCA TCGGGCCCTG AGGAGACAGG TGACAAGCCT CGTGGTTCTG
GGCAGTGCCA TGGAGCTCTG CGGGAATGAC TCGGTGTACG CCTACGCCTC CTCCGTGTTC
CGGAAGGCAG GAGTGCCGGA AGCGAAGATC CAGTACGCGA TCATCGGGAC TGGGAGCTGC
GAGCTGCTCA CGGCGGTTGT TAGTTGTGTG GTAATCGAGA GGGTGGGTCG GCGCGTGCTG
CTCATCGGTG GGTACAGCCT GATGACCTGC TGGGGGAGCA TCTTCACTGT GGCCCTGTGC
CTGCAGAGCT CCTTCCCCTG GACACTCTAC CTGGCCATGG CCTGCATCTT TGCCTTCATC
CTCAGCTTTG GCATTGGCCC TGCCGGAGTG ACGGGGATCC TGGCCACAGA GCTGTTTGAC
CAGATGGCCA GGCCTGCTGC CTGCATGGTC TGCGGGGCGC TCATGTGGAT CATGCTCATC
CTGGTCGGCC TGGGATTTCC CTTTATCATG GAGGCCTTGT CCCACTTCCT CTATGTCCCT
TTCCTTGGTG TCTGTGTCTG TGGGGCCATC TACACTGGCC TGTTCCTTCC TGAGACCAAA
GGCAAGACCT TCCAAGAGAT CTCCAAGGAA TTACACAGAC TCAACTTCCC CAGGCGGGCC
CAGGGCCCCA CGTGGAGGAG CCTGGAGGTT ATCCAGTCAA CAGAACTCTA G

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

Multiple myeloma exhibits novel dependence on GLUT4, GLUT8, and GLUT11: implications for glucose transporter-directed therapy.
Blood119(20)4686-97(2012 May)
McBrayer SK,Cheng JC,Singhal S,Krett NL,Rosen ST,Shanmugam M


book

A highly conserved hydrophobic motif in the exofacial vestibule of fructose transporting SLC2A proteins acts as a critical determinant of their substrate selectivity.
Molecular membrane biology24(5-6)455-63(2007 Sep-Dec)
Manolescu AR,Augustin R,Moley K,Cheeseman C


book

Characterization of the human SLC2A11 (GLUT11) gene: alternative promoter usage, function, expression, and subcellular distribution of three isoforms, and lack of mouse orthologue.
Molecular membrane biology22(4)339-51(2005 Jul-Aug)
Scheepers A,Schmidt S,Manolescu A,Cheeseman CI,Bell A,Zahn C,Joost HG,Schürmann A


book

GLUT11, but not GLUT8 or GLUT12, is expressed in human skeletal muscle in a fibre type-specific pattern.
Pflugers Archiv : European journal of physiology448(1)105-13(2004 Apr)
Gaster M,Handberg A,Schürmann A,Joost HG,Beck-Nielsen H,Schrøder HD


book

Cloning and characterization of glucose transporter 11, a novel sugar transporter that is alternatively spliced in various tissues.
Molecular genetics and metabolism76(1)37-45(2002 May)
Wu X,Li W,Sharma V,Godzik A,Freeze HH


 
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