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VIP cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol VIP
Entrez Gene ID 7432
Full Name vasoactive intestinal peptide
Synonyms PHM27
General protein information
Preferred Names

vasoactive intestinal peptide

Names

VIP peptides
prepro-VIP
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

6

6q25.2
Summary The protein encoded by this gene belongs to the glucagon family. It stimulates myocardial contractility, causes vasodilation, increases glycogenolysis, lowers arterial blood pressure and relaxes the smooth muscle of trachea, stomach and gall bladder. The protein also acts as an antimicrobial peptide with antibacterial and antifungal activity. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Nov 2014].
Disorder MIM:

192320


Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_006715562.3 XP_006715625.1 VIP peptides isoform X1
NM_003381.3 NP_003372.1 VIP peptides isoform 1 preproprotein
NM_194435.2 NP_919416.1 VIP peptides isoform 2 preproprotein
XM_005267135.3 XP_005267192.1 VIP peptides isoform X2

Pathways from BioSystems


Homologies


Mus musculus (house mouse) Vip NP_035832.1
Homo sapiens (human) VIP NP_003372.1
VIP XP_001096218.1
Bos taurus (cattle) VIP NP_776395.1
Gallus gallus (chicken) VIP NP_990697.2
Danio rerio (zebrafish) vip NP_001108025.1
Xenopus tropicalis (tropical clawed frog) vip XP_002936422.2
Pan troglodytes (chimpanzee) VIP XP_527541.2
Canis lupus familiaris (dog) VIP XP_541155.2
Rattus norvegicus (Norway rat) Vip NP_446443.1

Gene Ontology


Bibliography

Related articles in PubMed

Vasoactive Intestinal Polypeptide and Mast Cells Regulate Increased Passage of Colonic Bacteria in Patients With Irritable Bowel Syndrome.
Bednarska O, Walter SA, Casado-Bedmar M, Str?m M, Salvo-Romero E, Vicario M, Mayer EA, Keita ?V
Gastroenterology153(4)948-960.e3(2017 Oct)

Vasoactive intestinal peptide dampens formyl-peptide-induced ROS production and inflammation by targeting a MAPK-p47
Chedid P, Boussetta T, Dang PM, Belambri SA, Marzaioli V, Fasseau M, Walker F, Couvineau A, El-Benna J, Marie JC
Mucosal immunology10(2)332-340(2017 Mar)

NFATc3 and VIP in Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary Disease.
Szema AM, Forsyth E, Ying B, Hamidi SA, Chen JJ, Hwang S, Li JC, Sabatini Dwyer D, Ramiro-Diaz JM, Giermakowska W, Gonzalez Bosc LV
PloS one12(1)e0170606(2017)

VIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts.
P?rez-Garc?a S, Carri?n M, Guti?rrez-Ca?as I, Gonz?lez-?lvaro I, Gomariz RP, Juarranz Y
Journal of cellular and molecular medicine20(4)678-87(2016 Apr)

Opening Holes in the Blanket of Inhibition: Localized Lateral Disinhibition by VIP Interneurons.
Karnani MM, Jackson J, Ayzenshtat I, Hamzehei Sichani A, Manoocheri K, Kim S, Yuste R
The Journal of neuroscience : the official journal of the Society for Neuroscience36(12)3471-80(2016 Mar)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Both mast cells and VIP appear to be important factors in the regulation of this bacterial translocation through the colonic mucosa of irritable bowel syndrome patients.
Title: Vasoactive Intestinal Polypeptide and Mast Cells Regulate Increased Passage of Colonic Bacteria in Patients With Irritable Bowel Syndrome.

this study shows that that VIP exerts anti-inflammatory effects by inhibiting the MAPK-p47phox phosphorylation-NOX2 activation axis, and that VIP dampens carrageenan-induced inflammation in rats
Title: Vasoactive intestinal peptide dampens formyl-peptide-induced ROS production and inflammation by targeting a MAPK-p47

we found that VIP inhibits NFAT nuclear translocation in primary human pulmonary artery smooth muscle cells (PASMC). Early activation of NFATc3 in IPF patients may contribute to disease progression and the increase in VIP expression could be a protective compensatory mechanism
Title: NFATc3 and VIP in Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary Disease.

VIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts.
Title: VIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts.

optogenetically activating single VIPs in live mice while recording the activity of nearby neurons, we find that VIPs break open a hole in blanket inhibition.
Title: Opening Holes in the Blanket of Inhibition: Localized Lateral Disinhibition by VIP Interneurons.

The following VIP gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the VIP cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu14101 NM_194435.2
Latest version!		 Homo sapiens vasoactive intestinal peptide (VIP), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $69.30
$99.00
OHu27483 NM_003381.3
Latest version!		 Homo sapiens vasoactive intestinal peptide (VIP), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu40959 XM_006715562.3
Latest version!		 Homo sapiens vasoactive intestinal peptide (VIP), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OHu40960 XM_005267135.3
Latest version!		 Homo sapiens vasoactive intestinal peptide (VIP), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu14101
Clone ID Related Accession (Same CDS sequence) NM_194435.2
Accession Version NM_194435.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 510bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-11-13
Organism Homo sapiens(human)
Product VIP peptides isoform 2 preproprotein
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA914915.1, BC009794.1 and BM971673.1. On Jul 13, 2012 this sequence version replaced NM_194435.1. Transcript Variant: This variant (2) lacks an alternate in-frame segment, compared to variant 1, resulting in a shorter protein (isoform 2), compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803617.429716.1, BC009794.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 18603306 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
ATGGACACCA GAAATAAGGC CCAGCTCCTT GTGCTCCTGA CTCTTCTCAG TGTGCTCTTC 
TCACAGACTT CGGCATGGCC TCTTTACAGG GCACCTTCTG CTCTCAGGTT GGGTGACAGA 
ATACCCTTTG AGGGAGCAAA TGAACCTGAT CAAGTTTCAT TAAAAGAAGA CATTGACATG 
TTGCAAAATG CATTAGCTGA AAATGACACA CCCTATTATG ATGTATCCAG AAATGCCAGG 
CATGCTGATG GAGTTTTCAC CAGTGACTTC AGTAAACTCT TGGGTCAACT TTCTGCCAAA 
AAGTACCTTG AGTCTCTTAT GGGAAAACGT GTTAGTAACA TCTCAGAAGA CCCTGTACCA 
GTCAAACGTC ACTCAGATGC AGTCTTCACT GACAACTATA CCCGCCTTAG AAAACAAATG 
GCTGTAAAGA AATATTTGAA CTCAATTCTG AATGGAAAGA GGAGCAGTGA GGGAGAATCT 
CCCGACTTTC CAGAAGAGTT AGAAAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_919416.1
CDS174..683
Misc Feature(1)54..56
Misc Feature(2)414..494
Misc Feature(3)543..623
Exon (1)1..163
Exon (2)164..280
Exon (3)281..403
Exon (4)404..508
Exon (5)509..637
Exon (6)638..726
Exon (7)727..1582
Translation

Target ORF information:

RefSeq Version NM_194435.2
Organism Homo sapiens(human)
Definition Homo sapiens vasoactive intestinal peptide (VIP), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_194435.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGACACCA GAAATAAGGC CCAGCTCCTT GTGCTCCTGA CTCTTCTCAG TGTGCTCTTC 
TCACAGACTT CGGCATGGCC TCTTTACAGG GCACCTTCTG CTCTCAGGTT GGGTGACAGA 
ATACCCTTTG AGGGAGCAAA TGAACCTGAT CAAGTTTCAT TAAAAGAAGA CATTGACATG 
TTGCAAAATG CATTAGCTGA AAATGACACA CCCTATTATG ATGTATCCAG AAATGCCAGG 
CATGCTGATG GAGTTTTCAC CAGTGACTTC AGTAAACTCT TGGGTCAACT TTCTGCCAAA 
AAGTACCTTG AGTCTCTTAT GGGAAAACGT GTTAGTAACA TCTCAGAAGA CCCTGTACCA 
GTCAAACGTC ACTCAGATGC AGTCTTCACT GACAACTATA CCCGCCTTAG AAAACAAATG 
GCTGTAAAGA AATATTTGAA CTCAATTCTG AATGGAAAGA GGAGCAGTGA GGGAGAATCT 
CCCGACTTTC CAGAAGAGTT AGAAAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu27483
Clone ID Related Accession (Same CDS sequence) NM_003381.3
Accession Version NM_003381.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-11-13
Organism Homo sapiens(human)
Product VIP peptides isoform 1 preproprotein
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA914915.1, BC009794.1 and BM971673.1. On Jul 13, 2012 this sequence version replaced NM_003381.2. Transcript Variant: This variant (1) encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M36634.1, SRR1660809.107512.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## Protein has antimicrobial activity :: PMID: 18603306 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
ATGGACACCA GAAATAAGGC CCAGCTCCTT GTGCTCCTGA CTCTTCTCAG TGTGCTCTTC 
TCACAGACTT CGGCATGGCC TCTTTACAGG GCACCTTCTG CTCTCAGGTT GGGTGACAGA 
ATACCCTTTG AGGGAGCAAA TGAACCTGAT CAAGTTTCAT TAAAAGAAGA CATTGACATG 
TTGCAAAATG CATTAGCTGA AAATGACACA CCCTATTATG ATGTATCCAG AAATGCCAGG 
CATGCTGATG GAGTTTTCAC CAGTGACTTC AGTAAACTCT TGGGTCAACT TTCTGCCAAA 
AAGTACCTTG AGTCTCTTAT GGGAAAACGT GTTAGCAGTA ACATCTCAGA AGACCCTGTA 
CCAGTCAAAC GTCACTCAGA TGCAGTCTTC ACTGACAACT ATACCCGCCT TAGAAAACAA 
ATGGCTGTAA AGAAATATTT GAACTCAATT CTGAATGGAA AGAGGAGCAG TGAGGGAGAA 
TCTCCCGACT TTCCAGAAGA GTTAGAAAAA TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_003372.1
CDS174..686
Misc Feature(1)54..56
Misc Feature(2)414..494
Misc Feature(3)546..626
Exon (1)1..163
Exon (2)164..280
Exon (3)281..403
Exon (4)404..508
Exon (5)509..640
Exon (6)641..729
Exon (7)730..1585
Translation

Target ORF information:

RefSeq Version NM_003381.3
Organism Homo sapiens(human)
Definition Homo sapiens vasoactive intestinal peptide (VIP), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_003381.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGACACCA GAAATAAGGC CCAGCTCCTT GTGCTCCTGA CTCTTCTCAG TGTGCTCTTC 
TCACAGACTT CGGCATGGCC TCTTTACAGG GCACCTTCTG CTCTCAGGTT GGGTGACAGA 
ATACCCTTTG AGGGAGCAAA TGAACCTGAT CAAGTTTCAT TAAAAGAAGA CATTGACATG 
TTGCAAAATG CATTAGCTGA AAATGACACA CCCTATTATG ATGTATCCAG AAATGCCAGG 
CATGCTGATG GAGTTTTCAC CAGTGACTTC AGTAAACTCT TGGGTCAACT TTCTGCCAAA 
AAGTACCTTG AGTCTCTTAT GGGAAAACGT GTTAGCAGTA ACATCTCAGA AGACCCTGTA 
CCAGTCAAAC GTCACTCAGA TGCAGTCTTC ACTGACAACT ATACCCGCCT TAGAAAACAA 
ATGGCTGTAA AGAAATATTT GAACTCAATT CTGAATGGAA AGAGGAGCAG TGAGGGAGAA 
TCTCCCGACT TTCCAGAAGA GTTAGAAAAA TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu40959
Clone ID Related Accession (Same CDS sequence) XM_006715562.3
Accession Version XM_006715562.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 510bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(human)
Product VIP peptides isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_006715562.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
ATGGACACCA GAAATAAGGC CCAGCTCCTT GTGCTCCTGA CTCTTCTCAG TGTGCTCTTC 
TCACAGACTT CGGCATGGCC TCTTTACAGG GCACCTTCTG CTCTCAGGTT GGGTGACAGA 
ATACCCTTTG AGGGAGCAAA TGAACCTGAT CAAGTTTCAT TAAAAGAAGA CATTGACATG 
TTGCAAAATG CATTAGCTGA AAATGACACA CCCTATTATG ATGTATCCAG AAATGCCAGG 
CATGCTGATG GAGTTTTCAC CAGTGACTTC AGTAAACTCT TGGGTCAACT TTCTGCCAAA 
AAGTACCTTG AGTCTCTTAT GGGAAAACGT GTTAGCAGTA ACATCTCAGA AGACCCTGTA 
CCAGTCAAAC GTCACTCAGA TGCAGTCTTC ACTGACAACT ATACCCGCCT TAGAAAACAA 
ATGGCTGTAA AGAAATATTT GAACTCAATT CTGAATGGAA AGAGGAGTGA GGGAGAATCT 
CCCGACTTTC CAGAAGAGTT AGAAAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006715625.1
CDS3077..3586
Misc Feature(1)3317..3397
Misc Feature(2)3449..3529
Translation

Target ORF information:

RefSeq Version XM_006715562.3
Organism Homo sapiens(human)
Definition Homo sapiens vasoactive intestinal peptide (VIP), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006715562.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGACACCA GAAATAAGGC CCAGCTCCTT GTGCTCCTGA CTCTTCTCAG TGTGCTCTTC 
TCACAGACTT CGGCATGGCC TCTTTACAGG GCACCTTCTG CTCTCAGGTT GGGTGACAGA 
ATACCCTTTG AGGGAGCAAA TGAACCTGAT CAAGTTTCAT TAAAAGAAGA CATTGACATG 
TTGCAAAATG CATTAGCTGA AAATGACACA CCCTATTATG ATGTATCCAG AAATGCCAGG 
CATGCTGATG GAGTTTTCAC CAGTGACTTC AGTAAACTCT TGGGTCAACT TTCTGCCAAA 
AAGTACCTTG AGTCTCTTAT GGGAAAACGT GTTAGCAGTA ACATCTCAGA AGACCCTGTA 
CCAGTCAAAC GTCACTCAGA TGCAGTCTTC ACTGACAACT ATACCCGCCT TAGAAAACAA 
ATGGCTGTAA AGAAATATTT GAACTCAATT CTGAATGGAA AGAGGAGTGA GGGAGAATCT 
CCCGACTTTC CAGAAGAGTT AGAAAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu40960
Clone ID Related Accession (Same CDS sequence) XM_005267135.3
Accession Version XM_005267135.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 507bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(human)
Product VIP peptides isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000006.12) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005267135.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
ATGGACACCA GAAATAAGGC CCAGCTCCTT GTGCTCCTGA CTCTTCTCAG TGTGCTCTTC 
TCACAGACTT CGGCATGGCC TCTTTACAGG GCACCTTCTG CTCTCAGGTT GGGTGACAGA 
ATACCCTTTG AGGGAGCAAA TGAACCTGAT CAAGTTTCAT TAAAAGAAGA CATTGACATG 
TTGCAAAATG CATTAGCTGA AAATGACACA CCCTATTATG ATGTATCCAG AAATGCCAGG 
CATGCTGATG GAGTTTTCAC CAGTGACTTC AGTAAACTCT TGGGTCAACT TTCTGCCAAA 
AAGTACCTTG AGTCTCTTAT GGGAAAACGT GTTAGTAACA TCTCAGAAGA CCCTGTACCA 
GTCAAACGTC ACTCAGATGC AGTCTTCACT GACAACTATA CCCGCCTTAG AAAACAAATG 
GCTGTAAAGA AATATTTGAA CTCAATTCTG AATGGAAAGA GGAGTGAGGG AGAATCTCCC 
GACTTTCCAG AAGAGTTAGA AAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005267192.1
CDS126..632
Misc Feature(1)366..446
Misc Feature(2)495..575
Translation

Target ORF information:

RefSeq Version XM_005267135.3
Organism Homo sapiens(human)
Definition Homo sapiens vasoactive intestinal peptide (VIP), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_005267135.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGACACCA GAAATAAGGC CCAGCTCCTT GTGCTCCTGA CTCTTCTCAG TGTGCTCTTC 
TCACAGACTT CGGCATGGCC TCTTTACAGG GCACCTTCTG CTCTCAGGTT GGGTGACAGA 
ATACCCTTTG AGGGAGCAAA TGAACCTGAT CAAGTTTCAT TAAAAGAAGA CATTGACATG 
TTGCAAAATG CATTAGCTGA AAATGACACA CCCTATTATG ATGTATCCAG AAATGCCAGG 
CATGCTGATG GAGTTTTCAC CAGTGACTTC AGTAAACTCT TGGGTCAACT TTCTGCCAAA 
AAGTACCTTG AGTCTCTTAT GGGAAAACGT GTTAGTAACA TCTCAGAAGA CCCTGTACCA 
GTCAAACGTC ACTCAGATGC AGTCTTCACT GACAACTATA CCCGCCTTAG AAAACAAATG 
GCTGTAAAGA AATATTTGAA CTCAATTCTG AATGGAAAGA GGAGTGAGGG AGAATCTCCC 
GACTTTCCAG AAGAGTTAGA AAAATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Vasoactive Intestinal Polypeptide and Mast Cells Regulate Increased Passage of Colonic Bacteria in Patients With Irritable Bowel Syndrome.
Gastroenterology153(4)948-960.e3(2017 Oct)
Bednarska O,Walter SA,Casado-Bedmar M,Str?m M,Salvo-Romero E,Vicario M,Mayer EA,Keita ?V


book

Vasoactive intestinal peptide dampens formyl-peptide-induced ROS production and inflammation by targeting a MAPK-p47
Mucosal immunology10(2)332-340(2017 Mar)
Chedid P,Boussetta T,Dang PM,Belambri SA,Marzaioli V,Fasseau M,Walker F,Couvineau A,El-Benna J,Marie JC


book

NFATc3 and VIP in Idiopathic Pulmonary Fibrosis and Chronic Obstructive Pulmonary Disease.
PloS one12(1)e0170606(2017)
Szema AM,Forsyth E,Ying B,Hamidi SA,Chen JJ,Hwang S,Li JC,Sabatini Dwyer D,Ramiro-Diaz JM,Giermakowska W,Gonzalez Bosc LV


book

VIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts.
Journal of cellular and molecular medicine20(4)678-87(2016 Apr)
P?rez-Garc?a S,Carri?n M,Guti?rrez-Ca?as I,Gonz?lez-?lvaro I,Gomariz RP,Juarranz Y


book

Opening Holes in the Blanket of Inhibition: Localized Lateral Disinhibition by VIP Interneurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience36(12)3471-80(2016 Mar)
Karnani MM,Jackson J,Ayzenshtat I,Hamzehei Sichani A,Manoocheri K,Kim S,Yuste R