Gene Symbol | YIPF5 |
Entrez Gene ID | 81555 |
Full Name | Yip1 domain family member 5 |
Synonyms | FinGER5,SB140,SMAP-5,SMAP5,YIP1A |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » YIPF5 cDNA ORF clone
Gene Symbol | YIPF5 |
Entrez Gene ID | 81555 |
Full Name | Yip1 domain family member 5 |
Synonyms | FinGER5,SB140,SMAP-5,SMAP5,YIP1A |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_001024947.3 | NP_001020118.1 | protein YIPF5 isoform a |
NM_030799.9 | NP_110426.4 | protein YIPF5 isoform a |
NM_001271732.2 | NP_001258661.1 | protein YIPF5 isoform b |
NM_001024947.4 | NP_001020118.1 | protein YIPF5 isoform a |
NM_001271732.1 | NP_001258661.1 | protein YIPF5 isoform b |
NM_030799.8 | NP_110426.4 | protein YIPF5 isoform a |
Neurospora crassa | NCU05514 | XP_960476.1 |
Pan troglodytes (chimpanzee) | YIPF5 | XP_001155619.1 |
YIPF5 | XP_001098625.1 | |
Bos taurus (cattle) | YIPF5 | NP_001029715.1 |
Rattus norvegicus (Norway rat) | Yipf5 | NP_001014172.3 |
Mus musculus (house mouse) | Yipf5 | NP_075800.1 |
Gallus gallus (chicken) | YIPF5 | NP_001185566.1 |
Drosophila melanogaster (fruit fly) | CG12404 | NP_609596.1 |
Caenorhabditis elegans (roundworm) | F32D8.14 | NP_001256274.1 |
Arabidopsis thaliana (thale cress) | AT3G52760 | NP_190844.1 |
Oryza sativa (rice) | Os03g0289200 | NP_001049791.1 |
Xenopus tropicalis (tropical clawed frog) | yipf5 | NP_001007977.1 |
Canis lupus familiaris (dog) | YIPF5 | XP_535226.1 |
Danio rerio (zebrafish) | yipf5 | NP_956589.1 |
Saccharomyces cerevisiae (baker's yeast) | YIP1 | NP_011688.3 |
Eremothecium gossypii | AGOS_AAL135C | NP_982407.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_00407 | XP_003718669.1 |
Homo sapiens (human) | YIPF5 | NP_110426.4 |
Kluyveromyces lactis | KLLA0F15015g | XP_455755.1 |
Schizosaccharomyces pombe (fission yeast) | SPCC61.04c | NP_588195.1 |
Arabidopsis thaliana (thale cress) | AT2G36300 | NP_565842.1 |
Functional characterisation of the YIPF protein family in mammalian cells.
Kranjc T, Dempsey E, Cagney G, Nakamura N, Shields DC, Simpson JC
Histochemistry and cell biology147(4)439-451(2017 Apr)
A human interactome in three quantitative dimensions organized by stoichiometries and abundances.
Hein MY, Hubner NC, Poser I, Cox J, Nagaraj N, Toyoda Y, Gak IA, Weisswange I, Mansfeld J, Buchholz F, Hyman AA, Mann M
Cell163(3)712-23(2015 Oct)
Yip1A, a novel host factor for the activation of the IRE1 pathway of the unfolded protein response during Brucella infection.
Taguchi Y, Imaoka K, Kataoka M, Uda A, Nakatsu D, Horii-Okazaki S, Kunishige R, Kano F, Murata M
PLoS pathogens11(3)e1004747(2015 Mar)
The ALS8 protein VAPB interacts with the ER-Golgi recycling protein YIF1A and regulates membrane delivery into dendrites.
Kuijpers M, Yu KL, Teuling E, Akhmanova A, Jaarsma D, Hoogenraad CC
The EMBO journal32(14)2056-72(2013 Jul)
Identification of discrete sites in Yip1A necessary for regulation of endoplasmic reticulum structure.
Dykstra KM, Ulengin I, Delrose N, Lee TH
PloS one8(1)e54413(2013)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The significance of YIPF5 protein for the maintenance of the morphology of the Golgi was tested by RNA interference, revealing a number of specific morphological changes to this organelle on their depletion.
Title: Functional characterisation of the YIPF protein family in mammalian cells.
we propose a model for intracellular Brucella replication that exploits the host unfolded protein response and endoplasmic reticulum -derived vacuole formation machineries, both of which depend on Yip1A-mediated IRE1 activation.
Title: Yip1A, a novel host factor for the activation of the IRE1 pathway of the unfolded protein response during Brucella infection.
Findings suggest that the ability of Yip1A to bind its established binding partners may be uncoupled from its ability to control ER whorl formation.
Title: Identification of discrete sites in Yip1A necessary for regulation of endoplasmic reticulum structure.
Results reveal a conserved Yip1A-mediated mechanism for ER membrane organization that may serve to regulate cargo exit from the organelle.
Title: Yip1A structures the mammalian endoplasmic reticulum.
Observational study of gene-disease association. (HuGE Navigator)
Title: Fine mapping of the CELIAC2 locus on chromosome 5q31-q33 in the Finnish and Hungarian populations.
The following YIPF5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the YIPF5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu00412 | |
Clone ID Related Accession (Same CDS sequence) | NM_001271732.2 , NM_001271732.1 | |
Accession Version | NM_001271732.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 612bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-30 | |
Organism | Homo sapiens(human) | |
Product | protein YIPF5 isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP310538.1, AY640929.1 and AY640926.1. On May 31, 2019 this sequence version replaced NM_001271732.1. Transcript Variant: This variant (3) lacks an alternate exon in the 5' coding region and uses a downstream start codon, compared to variant 1. It encodes isoform b which has a shorter N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY640929.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGATGCAGC CACAACAGCC ATACACCGGG CAGATTTACC AGCCAACTCA GGCATATACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001258661.1 |
CDS | 429..1040 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001271732.2 |
1 | ATGATGCAGC CACAACAGCC ATACACCGGG CAGATTTACC AGCCAACTCA GGCATATACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu00412 | |
Clone ID Related Accession (Same CDS sequence) | NM_001271732.2 , NM_001271732.1 | |
Accession Version | NM_001271732.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 612bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-24 | |
Organism | Homo sapiens(human) | |
Product | protein YIPF5 isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP310538.1, AY640929.1, AY640926.1 and AA811265.1. Transcript Variant: This variant (3) lacks an alternate exon in the 5' coding region and uses a downstream start codon, compared to variant 1. It encodes isoform b which has a shorter N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY640929.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGATGCAGC CACAACAGCC ATACACCGGG CAGATTTACC AGCCAACTCA GGCATATACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001258661.1 |
CDS | 484..1095 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001271732.1 |
1 | ATGATGCAGC CACAACAGCC ATACACCGGG CAGATTTACC AGCCAACTCA GGCATATACT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu00585 | |
Clone ID Related Accession (Same CDS sequence) | NM_001024947.3 , NM_030799.9 , NM_001024947.4 , NM_030799.8 | |
Accession Version | NM_001024947.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-06-24 | |
Organism | Homo sapiens(human) | |
Product | protein YIPF5 isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP310538.1, AY640928.1, AY640926.1 and AA811265.1. On Nov 10, 2012 this sequence version replaced NM_001024947.2. Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 encode the same protein (isoform a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY640928.1, AK124065.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCAGGCT TTGAAAACTT AAACACGGAT TTCTACCAGA CAAGTTACAG CATCGATGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001020118.1 |
CDS | 442..1215 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001024947.3 |
1 | ATGTCAGGCT TTGAAAACTT AAACACGGAT TTCTACCAGA CAAGTTACAG CATCGATGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu00585 | |
Clone ID Related Accession (Same CDS sequence) | NM_001024947.3 , NM_030799.9 , NM_001024947.4 , NM_030799.8 | |
Accession Version | NM_030799.9 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-01 | |
Organism | Homo sapiens(human) | |
Product | protein YIPF5 isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP310538.1 and AY640926.1. On Nov 23, 2018 this sequence version replaced NM_030799.8. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein (isoform a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.92146.1, SRR1803613.113151.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000274496.10/ ENSP00000274496.5 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGTCAGGCT TTGAAAACTT AAACACGGAT TTCTACCAGA CAAGTTACAG CATCGATGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_110426.4 |
CDS | 136..909 |
Translation |
Target ORF information:
Target ORF information:
|
NM_030799.9 |
1 | ATGTCAGGCT TTGAAAACTT AAACACGGAT TTCTACCAGA CAAGTTACAG CATCGATGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu00585 | |
Clone ID Related Accession (Same CDS sequence) | NM_001024947.3 , NM_030799.9 , NM_001024947.4 , NM_030799.8 | |
Accession Version | NM_001024947.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-05-30 | |
Organism | Homo sapiens(human) | |
Product | protein YIPF5 isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP310538.1, AY640928.1 and AY640926.1. On May 31, 2019 this sequence version replaced NM_001024947.3. Transcript Variant: This variant (1) represents the longest transcript. Variants 1 and 2 encode the same protein (isoform a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AY640928.1, SRR1660805.182170.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCAGGCT TTGAAAACTT AAACACGGAT TTCTACCAGA CAAGTTACAG CATCGATGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001020118.1 |
CDS | 387..1160 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001024947.4 |
1 | ATGTCAGGCT TTGAAAACTT AAACACGGAT TTCTACCAGA CAAGTTACAG CATCGATGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu00585 | |
Clone ID Related Accession (Same CDS sequence) | NM_001024947.3 , NM_030799.9 , NM_001024947.4 , NM_030799.8 | |
Accession Version | NM_030799.8 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 774bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-02 | |
Organism | Homo sapiens(human) | |
Product | protein YIPF5 isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP310538.1, AY640926.1 and AA811265.1. On Nov 10, 2012 this sequence version replaced NM_030799.7. Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. Variants 1 and 2 encode the same protein (isoform a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.71929.1, SRR1803613.113151.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA1965299, SAMEA1966682 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCAGGCT TTGAAAACTT AAACACGGAT TTCTACCAGA CAAGTTACAG CATCGATGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_110426.4 |
CDS | 191..964 |
Translation |
Target ORF information:
Target ORF information:
|
NM_030799.8 |
1 | ATGTCAGGCT TTGAAAACTT AAACACGGAT TTCTACCAGA CAAGTTACAG CATCGATGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Functional characterisation of the YIPF protein family in mammalian cells. |
A human interactome in three quantitative dimensions organized by stoichiometries and abundances. |
Yip1A, a novel host factor for the activation of the IRE1 pathway of the unfolded protein response during Brucella infection. |
The ALS8 protein VAPB interacts with the ER-Golgi recycling protein YIF1A and regulates membrane delivery into dendrites. |
Identification of discrete sites in Yip1A necessary for regulation of endoplasmic reticulum structure. |