JMJD7-PLA2G4B cDNA ORF clone, Homo sapiens(human)

Gene
Clones
gRNAs

Summary

Gene Symbol	JMJD7-PLA2G4B
Entrez Gene ID	8681
Full Name	JMJD7-PLA2G4B readthrough
Synonyms	HsT16992,cPLA2-beta
General protein information	Preferred Names JMJD7-PLA2G4B readthrough Names JMJD7-PLA2G4B protein jumonji domain containing 7-phospholipase A2, group IVB (cytosolic) read-through
Gene Type	protein-coding
Organism	Homo sapiens(human)
Genome	Chromosome: 15 Map Location: 15q15.1
Summary	This locus represents naturally-occurring readthrough transcription between the neighboring jumonji domain containing 7 (JMJD7) and phospholipase A2, group IVB (cytosolic) (PLA2G4B) genes. Readthrough transcripts encode fusion proteins that share amino acid sequence with each individual gene product, including a partial JmjC domain and downstream C2 and phospholipase A2 domains. Alternatively spliced transcript variants have been observed. [provided by RefSeq, Oct 2013].

mRNA and Protein(s)

mRNA	Protein	Name
NM_005090.3	NP_005081.1	JMJD7-PLA2G4B protein isoform a
NM_001198588.1	NP_001185517.1	JMJD7-PLA2G4B protein isoform b

Pathways from BioSystems

Homologies

	JMJD7	XP_001101520.1
Homo sapiens (human)	JMJD7-PLA2G4B	NP_005081.1

Gene Ontology
Bibliography

Related articles in PubMed

Expression of conjoined genes: another mechanism for gene regulation in eukaryotes.
Prakash T, Sharma VK, Adati N, Ozawa R, Kumar N, Nishida Y, Fujikake T, Takeda T, Taylor TD
PloS one5(10)e13284(2010 Oct)

Identification of the expressed form of human cytosolic phospholipase A2beta (cPLA2beta): cPLA2beta3 is a novel variant localized to mitochondria and early endosomes.
Ghosh M, Loper R, Gelb MH, Leslie CC
The Journal of biological chemistry281(24)16615-24(2006 Jun)

Cytosolic PLA2 genes possibly contribute to the etiology of schizophrenia.
Tao R, Yu Y, Zhang X, Guo Y, Shi J, Zhang X, Xie L, Liu S, Ju G, Xu Q, Shen Y, Wei J
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics137B(1)56-8(2005 Aug)

Association analysis of two candidate phospholipase genes that map to the chromosome 15q15.1-15.3 region associated with reading disability.
Morris DW, Ivanov D, Robinson L, Williams N, Stevenson J, Owen MJ, Williams J, O'Donovan MC
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics129B(1)97-103(2004 Aug)

Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis.
Degousee N, Ghomashchi F, Stefanski E, Singer A, Smart BP, Borregaard N, Reithmeier R, Lindsay TF, Lichtenberger C, Reinisch W, Lambeau G, Arm J, Tischfield J, Gelb MH, Rubin BB
The Journal of biological chemistry277(7)5061-73(2002 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Observational study of gene-disease association, gene-environment interaction, and pharmacogenomic / toxicogenomic. (HuGE Navigator)
Title: Variation at the NFATC2 locus increases the risk of thiazolidinedione-induced edema in the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) study.

Observational study of gene-disease association. (HuGE Navigator)
Title: Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.

Observational study of gene-disease association. (HuGE Navigator)
Title: Cytosolic PLA2 genes possibly contribute to the etiology of schizophrenia.

Observational study of gene-disease association. (HuGE Navigator)
Title: Association analysis of two candidate phospholipase genes that map to the chromosome 15q15.1-15.3 region associated with reading disability.

circulating human neutrophils express groups V and X sPLA(2) (GV and GX sPLA(2)) mRNA and contain GV and GX sPLA(2) proteins, whereas GIB, GIIA, GIID, GIIE, GIIF, GIII, and GXII sPLA(2)s are undetectable
Title: Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis.

The following JMJD7-PLA2G4B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the JMJD7-PLA2G4B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OHu01995	NM_001198588.1 Latest version!	Homo sapiens JMJD7-PLA2G4B readthrough (JMJD7-PLA2G4B), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$629.30 $899.00
OHu18178	NM_005090.3 Latest version!	Homo sapiens JMJD7-PLA2G4B readthrough (JMJD7-PLA2G4B), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	20	$559.30 $799.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

JMJD7-PLA2G4B ( NM_001198588.1 ) cDNA ORF clone, Homo sapiens(human) -> NP_001185517.1 Homo sapiens JMJD7-PLA2G4B readthrough (JMJD7-PLA2G4B), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OHu01995
Clone ID Related Accession (Same CDS sequence)	NM_001198588.1
Accession Version	NM_001198588.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2682bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-30
Organism	Homo sapiens(human)
Product	JMJD7-PLA2G4B protein isoform b
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA096882.1, DQ523799.1, AC020659.5, BC013415.2 and AA064721.1. Transcript Variant: This variant (3, also known as cPLA2 beta2) lacks an alternate exon resulting in a frameshift in the 3' coding region, compared to variant 1. The encoded isoform (b) has a distinct and shorter C-terminus, compared to isoform a. ##Evidence-Data-START## Transcript exon combination :: DQ523799.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA2142670 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## readthrough transcript :: includes exons from GeneID 100137047, 100137049 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGAGG CGGCTTTGGA AGCCGTGCGG AGCGAGTTAC GAGAATTCCC GGCCGCTGCA 
AGGGAGCTCT GCGTGCCTCT TGCTGTGCCC TACCTGGACA AACCCCCAAC TCCGCTCCAC 
TTCTACCGGG ACTGGGTCTG CCCCAACAGG CCGTGCATTA TCCGCAACGC TCTGCAGCAC 
TGGCCGGCCC TCCAGAAGTG GTCCCTCCCC TATTTCAGAG CCACAGTGGG CTCCACAGAG 
GTGAGTGTGG CCGTGACCCC AGATGGTTAC GCGGATGCCG TGAGAGGGGA TCGCTTCATG 
ATGCCAGCTG AGCGCCGCCT GCCCCTGAGC TTCGTGCTGG ATGTGCTGGA GGGCCGGGCC 
CAGCACCCTG GAGTCCTCTA TGTGCAGAAG CAGTGCTCCA ACCTGCCCAG CGAGCTGCCC 
CAGCTGCTGC CTGATCTGGA ATCCCATGTG CCCTGGGCCT CCGAAGCCCT GGGAAAGATG 
CCCGATGCTG TGAACTTCTG GCTGGGGGAG GCGGCTGCAG TGACTTCTTT GCACAAGGAC 
CACTATGAGA ACCTCTACTG CGTGGTCTCA GGAGAGAAGC ATTTCCTGTT CCATCCGCCC 
AGCGACCGGC CCTTCATCCC CTATGAGCTG TACACGCCGG CAACCTACCA GCTAACTGAA 
GAGGGCACCT TTAAGGTGGT GGATGAAGAG GCCATGGAGA AGGCAGAGGT GTCCAGGACC 
TGCCTGCTCA CGGTTCGTGT CCTGCAGGCC CATCGCCTAC CCTCTAAGGA CCTAGTGACC 
CCCTCTGACT GCTACGTGAC TCTCTGGCTG CCCACGGCCT GCAGCCACAG GCTCCAGACA 
CGCACGGTCA AGAACAGCAG TAGCCCTGTC TGGAACCAGA GCTTTCACTT CAGGATCCAC 
AGGCAGCTCA AGAATGTCAT GGAACTGAAA GTCTTTGACC AGGACCTGGT GACCGGAGAT 
GACCCTGTGT TGTCAGTACT GTTTGATGCG GGGACTCTGC GGGCTGGGGA GTTCCGGCGC 
GAGAGCTTCT CACTGAGCCC TCAGGGTGAG GGGCGCCTGG AAGTTGAATT TCGCCTGCAG 
AGTCTGGCTG ACCGTGGCGA GTGGCTCGTC AGCAATGGCG TTCTGGTGGC CCGGGAGCTC 
TCCTGCTTGC ACGTTCAACT GGAGGAGACA GGAGACCAGA AGTCCTCAGA GCACAGAGTT 
CAGCTTGTGG TTCCTGGGTC CTGTGAGGGT CCGCAGGAGG CCTCTGTGGG CACTGGCACC 
TTCCGCTTCC ACTGCCCAGC CTGCTGGGAG CAGGAGCTGA GTATTCGCCT GCAGGATGCC 
CCCGAGGAGC AACTAAAGGC GCCACTGAGT GCCCTGCCCT CTGGTCAAGT GGTGAGGCTT 
GTCTTCCCCA CGTCCCAGGA GCCCCTGATG AGAGTGGAGC TGAAAAAAGA AGCAGGACTG 
AGGGAGCTGG CCGTGCGACT GGGCTTCGGG CCCTGTGCAG AGGAGCAGGC CTTCCTGAGC 
AGGAGGAAGC AGGTGGTGGC CGCGGCCTTG AGGCAGGCCC TGCAGCTGGA CGGAGACCTG 
CAGGAGGATG AGATCCCAGT GGTAGCTATT ATGGCCACTG GTGGTGGGAT CCGGGCAATG 
ACTTCCCTGT ATGGGCAGCT GGCTGGCCTG AAGGAGCTGG GCCTCTTGGA TTGCGTCTCC 
TACATCACCG GGGCCTCGGG CTCCACCTGG GCCTTGGCCA ACCTTTATGA GGACCCAGAG 
TGGTCTCAGA AGGACCTGGC AGGGCCCACT GAGTTGCTGA AGACCCAGGT GACCAAGAAC 
AAGCTGGGTG TGCTGGCCCC CAGCCAGCTG CAGCGGTACC GGCAGGAGCT GGCCGAGCGT 
GCCCGCTTGG GCTACCCAAG CTGCTTCACC AACCTGTGGG CCCTCATCAA CGAGGCGCTG 
CTGCATGATG AGCCCCATGA TCACAAGCTC TCAGATCAAC GGGAGGCCCT GAGTCATGGC 
CAGAACCCTC TGCCCATCTA CTGTGCCCTC AACACCAAAG GGCAGAGCCT GACCACTTTT 
GAATTTGGGG AGTGGTGCGA GTTCTCTCCC TACGAGGTCG GCTTCCCCAA GTACGGGGCC 
TTCATCCCCT CTGAGCTCTT TGGCTCCGAG TTCTTTATGG GGCAGCTGAT GAAGAGGCTT 
CCTGAGTCCC GCATCTGCTT CTTAGAAGGT ATCTGGAGCA ACCTGTATGC AGCCAACCTC 
CAGGACAGCT TATACTGGGC CTCAGAGCCC AGCCAGTTCT GGGACCGCTG GGTCAGGAAC 
CAGGCCAACC TGGACAAGGA GCAGGTCCCC CTTCTGAAGA TAGAAGAACC ACCCTCAACA 
GCCGGCAGGA TAGCTGAGTT TTTCACCGAT CTTCTGACGT GGCGTCCACT GGCCCAGGCC 
ACACATAATT TCCTGCGTGG CCTCCATTTC CACAAAGACT ACTTTCAGCA TCCTCACTTC 
TCCACATGGA AAGCTACCAC TCTGGATGGG CTCCCCAACC AGCTGACACC CTCGGAGCCC 
CACCTGTGCC TGCTGGATGT TGGCTACCTC ATCAATACCA GCTGCCTGCC CCTCCTGCAG 
CCCACTCGGG ACGTGGACCT CATCCTGTCA TTGGACTACA ACCTCCACGG AGCCTTCCAG 
GGGTCCGGCG GACACCCGAG GAGGCGGCAG CTGGGGAGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001185517.1
CDS	41..2722
Translation	MAEAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQHWPALQKWSLPYFRATVGSTEVSVAVTPDGYADAVRGDRFMMPAERRLPLSFVLDVLEGRAQHPGVLYVQKQCSNLPSELPQLLPDLESHVPWASEALGKMPDAVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVVDEEAMEKAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGPQEASVGTGTFRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMRVELKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPLLKIEEPPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQGSGGHPRRRQLGR

Target ORF information:

RefSeq Version	NM_001198588.1
Organism	Homo sapiens(human)
Definition	Homo sapiens JMJD7-PLA2G4B readthrough (JMJD7-PLA2G4B), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001198588.1

ORF Insert Sequence:

ATGGCGGAGG CGGCTTTGGA AGCCGTGCGG AGCGAGTTAC GAGAATTCCC GGCCGCTGCA 
AGGGAGCTCT GCGTGCCTCT TGCTGTGCCC TACCTGGACA AACCCCCAAC TCCGCTCCAC 
TTCTACCGGG ACTGGGTCTG CCCCAACAGG CCGTGCATTA TCCGCAACGC TCTGCAGCAC 
TGGCCGGCCC TCCAGAAGTG GTCCCTCCCC TATTTCAGAG CCACAGTGGG CTCCACAGAG 
GTGAGTGTGG CCGTGACCCC AGATGGTTAC GCGGATGCCG TGAGAGGGGA TCGCTTCATG 
ATGCCAGCTG AGCGCCGCCT GCCCCTGAGC TTCGTGCTGG ATGTGCTGGA GGGCCGGGCC 
CAGCACCCTG GAGTCCTCTA TGTGCAGAAG CAGTGCTCCA ACCTGCCCAG CGAGCTGCCC 
CAGCTGCTGC CTGATCTGGA ATCCCATGTG CCCTGGGCCT CCGAAGCCCT GGGAAAGATG 
CCCGATGCTG TGAACTTCTG GCTGGGGGAG GCGGCTGCAG TGACTTCTTT GCACAAGGAC 
CACTATGAGA ACCTCTACTG CGTGGTCTCA GGAGAGAAGC ATTTCCTGTT CCATCCGCCC 
AGCGACCGGC CCTTCATCCC CTATGAGCTG TACACGCCGG CAACCTACCA GCTAACTGAA 
GAGGGCACCT TTAAGGTGGT GGATGAAGAG GCCATGGAGA AGGCAGAGGT GTCCAGGACC 
TGCCTGCTCA CGGTTCGTGT CCTGCAGGCC CATCGCCTAC CCTCTAAGGA CCTAGTGACC 
CCCTCTGACT GCTACGTGAC TCTCTGGCTG CCCACGGCCT GCAGCCACAG GCTCCAGACA 
CGCACGGTCA AGAACAGCAG TAGCCCTGTC TGGAACCAGA GCTTTCACTT CAGGATCCAC 
AGGCAGCTCA AGAATGTCAT GGAACTGAAA GTCTTTGACC AGGACCTGGT GACCGGAGAT 
GACCCTGTGT TGTCAGTACT GTTTGATGCG GGGACTCTGC GGGCTGGGGA GTTCCGGCGC 
GAGAGCTTCT CACTGAGCCC TCAGGGTGAG GGGCGCCTGG AAGTTGAATT TCGCCTGCAG 
AGTCTGGCTG ACCGTGGCGA GTGGCTCGTC AGCAATGGCG TTCTGGTGGC CCGGGAGCTC 
TCCTGCTTGC ACGTTCAACT GGAGGAGACA GGAGACCAGA AGTCCTCAGA GCACAGAGTT 
CAGCTTGTGG TTCCTGGGTC CTGTGAGGGT CCGCAGGAGG CCTCTGTGGG CACTGGCACC 
TTCCGCTTCC ACTGCCCAGC CTGCTGGGAG CAGGAGCTGA GTATTCGCCT GCAGGATGCC 
CCCGAGGAGC AACTAAAGGC GCCACTGAGT GCCCTGCCCT CTGGTCAAGT GGTGAGGCTT 
GTCTTCCCCA CGTCCCAGGA GCCCCTGATG AGAGTGGAGC TGAAAAAAGA AGCAGGACTG 
AGGGAGCTGG CCGTGCGACT GGGCTTCGGG CCCTGTGCAG AGGAGCAGGC CTTCCTGAGC 
AGGAGGAAGC AGGTGGTGGC CGCGGCCTTG AGGCAGGCCC TGCAGCTGGA CGGAGACCTG 
CAGGAGGATG AGATCCCAGT GGTAGCTATT ATGGCCACTG GTGGTGGGAT CCGGGCAATG 
ACTTCCCTGT ATGGGCAGCT GGCTGGCCTG AAGGAGCTGG GCCTCTTGGA TTGCGTCTCC 
TACATCACCG GGGCCTCGGG CTCCACCTGG GCCTTGGCCA ACCTTTATGA GGACCCAGAG 
TGGTCTCAGA AGGACCTGGC AGGGCCCACT GAGTTGCTGA AGACCCAGGT GACCAAGAAC 
AAGCTGGGTG TGCTGGCCCC CAGCCAGCTG CAGCGGTACC GGCAGGAGCT GGCCGAGCGT 
GCCCGCTTGG GCTACCCAAG CTGCTTCACC AACCTGTGGG CCCTCATCAA CGAGGCGCTG 
CTGCATGATG AGCCCCATGA TCACAAGCTC TCAGATCAAC GGGAGGCCCT GAGTCATGGC 
CAGAACCCTC TGCCCATCTA CTGTGCCCTC AACACCAAAG GGCAGAGCCT GACCACTTTT 
GAATTTGGGG AGTGGTGCGA GTTCTCTCCC TACGAGGTCG GCTTCCCCAA GTACGGGGCC 
TTCATCCCCT CTGAGCTCTT TGGCTCCGAG TTCTTTATGG GGCAGCTGAT GAAGAGGCTT 
CCTGAGTCCC GCATCTGCTT CTTAGAAGGT ATCTGGAGCA ACCTGTATGC AGCCAACCTC 
CAGGACAGCT TATACTGGGC CTCAGAGCCC AGCCAGTTCT GGGACCGCTG GGTCAGGAAC 
CAGGCCAACC TGGACAAGGA GCAGGTCCCC CTTCTGAAGA TAGAAGAACC ACCCTCAACA 
GCCGGCAGGA TAGCTGAGTT TTTCACCGAT CTTCTGACGT GGCGTCCACT GGCCCAGGCC 
ACACATAATT TCCTGCGTGG CCTCCATTTC CACAAAGACT ACTTTCAGCA TCCTCACTTC 
TCCACATGGA AAGCTACCAC TCTGGATGGG CTCCCCAACC AGCTGACACC CTCGGAGCCC 
CACCTGTGCC TGCTGGATGT TGGCTACCTC ATCAATACCA GCTGCCTGCC CCTCCTGCAG 
CCCACTCGGG ACGTGGACCT CATCCTGTCA TTGGACTACA ACCTCCACGG AGCCTTCCAG 
GGGTCCGGCG GACACCCGAG GAGGCGGCAG CTGGGGAGGT GA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

JMJD7-PLA2G4B ( NM_005090.3 ) cDNA ORF clone, Homo sapiens(human) -> NP_005081.1 Homo sapiens JMJD7-PLA2G4B readthrough (JMJD7-PLA2G4B), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OHu18178
Clone ID Related Accession (Same CDS sequence)	NM_005090.3
Accession Version	NM_005090.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3039bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-30
Organism	Homo sapiens(human)
Product	JMJD7-PLA2G4B protein isoform a
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA096882.1, AF065215.1, DA080158.1, BI768993.1, BU688449.1 and AA064721.1. This sequence is a reference standard in the RefSeqGene project. On Feb 15, 2008 this sequence version replaced NM_005090.2. Transcript Variant: This variant (1, also known as cPLA2 beta) represents the longer transcript and encodes the longer isoform (a). ##Evidence-Data-START## Transcript exon combination :: AF065215.1, AF121908.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968540 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## readthrough transcript :: includes exons from GeneID 100137047, 100137049 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGCGGAGG CGGCTTTGGA AGCCGTGCGG AGCGAGTTAC GAGAATTCCC GGCCGCTGCA 
AGGGAGCTCT GCGTGCCTCT TGCTGTGCCC TACCTGGACA AACCCCCAAC TCCGCTCCAC 
TTCTACCGGG ACTGGGTCTG CCCCAACAGG CCGTGCATTA TCCGCAACGC TCTGCAGCAC 
TGGCCGGCCC TCCAGAAGTG GTCCCTCCCC TATTTCAGAG CCACAGTGGG CTCCACAGAG 
GTGAGTGTGG CCGTGACCCC AGATGGTTAC GCGGATGCCG TGAGAGGGGA TCGCTTCATG 
ATGCCAGCTG AGCGCCGCCT GCCCCTGAGC TTCGTGCTGG ATGTGCTGGA GGGCCGGGCC 
CAGCACCCTG GAGTCCTCTA TGTGCAGAAG CAGTGCTCCA ACCTGCCCAG CGAGCTGCCC 
CAGCTGCTGC CTGATCTGGA ATCCCATGTG CCCTGGGCCT CCGAAGCCCT GGGAAAGATG 
CCCGATGCTG TGAACTTCTG GCTGGGGGAG GCGGCTGCAG TGACTTCTTT GCACAAGGAC 
CACTATGAGA ACCTCTACTG CGTGGTCTCA GGAGAGAAGC ATTTCCTGTT CCATCCGCCC 
AGCGACCGGC CCTTCATCCC CTATGAGCTG TACACGCCGG CAACCTACCA GCTAACTGAA 
GAGGGCACCT TTAAGGTGGT GGATGAAGAG GCCATGGAGA AGGCAGAGGT GTCCAGGACC 
TGCCTGCTCA CGGTTCGTGT CCTGCAGGCC CATCGCCTAC CCTCTAAGGA CCTAGTGACC 
CCCTCTGACT GCTACGTGAC TCTCTGGCTG CCCACGGCCT GCAGCCACAG GCTCCAGACA 
CGCACGGTCA AGAACAGCAG TAGCCCTGTC TGGAACCAGA GCTTTCACTT CAGGATCCAC 
AGGCAGCTCA AGAATGTCAT GGAACTGAAA GTCTTTGACC AGGACCTGGT GACCGGAGAT 
GACCCTGTGT TGTCAGTACT GTTTGATGCG GGGACTCTGC GGGCTGGGGA GTTCCGGCGC 
GAGAGCTTCT CACTGAGCCC TCAGGGTGAG GGGCGCCTGG AAGTTGAATT TCGCCTGCAG 
AGTCTGGCTG ACCGTGGCGA GTGGCTCGTC AGCAATGGCG TTCTGGTGGC CCGGGAGCTC 
TCCTGCTTGC ACGTTCAACT GGAGGAGACA GGAGACCAGA AGTCCTCAGA GCACAGAGTT 
CAGCTTGTGG TTCCTGGGTC CTGTGAGGGT CCGCAGGAGG CCTCTGTGGG CACTGGCACC 
TTCCGCTTCC ACTGCCCAGC CTGCTGGGAG CAGGAGCTGA GTATTCGCCT GCAGGATGCC 
CCCGAGGAGC AACTAAAGGC GCCACTGAGT GCCCTGCCCT CTGGTCAAGT GGTGAGGCTT 
GTCTTCCCCA CGTCCCAGGA GCCCCTGATG AGAGTGGAGC TGAAAAAAGA AGCAGGACTG 
AGGGAGCTGG CCGTGCGACT GGGCTTCGGG CCCTGTGCAG AGGAGCAGGC CTTCCTGAGC 
AGGAGGAAGC AGGTGGTGGC CGCGGCCTTG AGGCAGGCCC TGCAGCTGGA CGGAGACCTG 
CAGGAGGATG AGATCCCAGT GGTAGCTATT ATGGCCACTG GTGGTGGGAT CCGGGCAATG 
ACTTCCCTGT ATGGGCAGCT GGCTGGCCTG AAGGAGCTGG GCCTCTTGGA TTGCGTCTCC 
TACATCACCG GGGCCTCGGG CTCCACCTGG GCCTTGGCCA ACCTTTATGA GGACCCAGAG 
TGGTCTCAGA AGGACCTGGC AGGGCCCACT GAGTTGCTGA AGACCCAGGT GACCAAGAAC 
AAGCTGGGTG TGCTGGCCCC CAGCCAGCTG CAGCGGTACC GGCAGGAGCT GGCCGAGCGT 
GCCCGCTTGG GCTACCCAAG CTGCTTCACC AACCTGTGGG CCCTCATCAA CGAGGCGCTG 
CTGCATGATG AGCCCCATGA TCACAAGCTC TCAGATCAAC GGGAGGCCCT GAGTCATGGC 
CAGAACCCTC TGCCCATCTA CTGTGCCCTC AACACCAAAG GGCAGAGCCT GACCACTTTT 
GAATTTGGGG AGTGGTGCGA GTTCTCTCCC TACGAGGTCG GCTTCCCCAA GTACGGGGCC 
TTCATCCCCT CTGAGCTCTT TGGCTCCGAG TTCTTTATGG GGCAGCTGAT GAAGAGGCTT 
CCTGAGTCCC GCATCTGCTT CTTAGAAGGT ATCTGGAGCA ACCTGTATGC AGCCAACCTC 
CAGGACAGCT TATACTGGGC CTCAGAGCCC AGCCAGTTCT GGGACCGCTG GGTCAGGAAC 
CAGGCCAACC TGGACAAGGA GCAGGTCCCC CTTCTGAAGA TAGAAGAACC ACCCTCAACA 
GCCGGCAGGA TAGCTGAGTT TTTCACCGAT CTTCTGACGT GGCGTCCACT GGCCCAGGCC 
ACACATAATT TCCTGCGTGG CCTCCATTTC CACAAAGACT ACTTTCAGCA TCCTCACTTC 
TCCACATGGA AAGCTACCAC TCTGGATGGG CTCCCCAACC AGCTGACACC CTCGGAGCCC 
CACCTGTGCC TGCTGGATGT TGGCTACCTC ATCAATACCA GCTGCCTGCC CCTCCTGCAG 
CCCACTCGGG ACGTGGACCT CATCCTGTCA TTGGACTACA ACCTCCACGG AGCCTTCCAG 
CAGTTGCAGC TCCTGGGCCG GTTCTGCCAG GAGCAGGGGA TCCCGTTCCC ACCCATCTCG 
CCCAGCCCCG AAGAGCAGCT CCAGCCTCGG GAGTGCCACA CCTTCTCCGA CCCCACCTGC 
CCCGGAGCCC CTGCGGTGCT GCACTTTCCT CTGGTCAGCG ACTCCTTCCG GGAGTACTCG 
GCCCCTGGGG TCCGGCGGAC ACCCGAGGAG GCGGCAGCTG GGGAGGTGAA CCTGTCTTCA 
TCGGACTCTC CCTACCACTA CACGAAGGTG ACCTACAGCC AGGAGGACGT GGACAAGCTG 
CTGCACCTGA CACATTACAA TGTCTGCAAC AACCAGGAGC AGCTGCTGGA GGCTCTGCGC 
CAGGCAGTGC AGCGGAGGCG GCAGCGCAGG CCCCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_005081.1
CDS	41..3079
Translation	MAEAALEAVRSELREFPAAARELCVPLAVPYLDKPPTPLHFYRDWVCPNRPCIIRNALQHWPALQKWSLPYFRATVGSTEVSVAVTPDGYADAVRGDRFMMPAERRLPLSFVLDVLEGRAQHPGVLYVQKQCSNLPSELPQLLPDLESHVPWASEALGKMPDAVNFWLGEAAAVTSLHKDHYENLYCVVSGEKHFLFHPPSDRPFIPYELYTPATYQLTEEGTFKVVDEEAMEKAEVSRTCLLTVRVLQAHRLPSKDLVTPSDCYVTLWLPTACSHRLQTRTVKNSSSPVWNQSFHFRIHRQLKNVMELKVFDQDLVTGDDPVLSVLFDAGTLRAGEFRRESFSLSPQGEGRLEVEFRLQSLADRGEWLVSNGVLVARELSCLHVQLEETGDQKSSEHRVQLVVPGSCEGPQEASVGTGTFRFHCPACWEQELSIRLQDAPEEQLKAPLSALPSGQVVRLVFPTSQEPLMRVELKKEAGLRELAVRLGFGPCAEEQAFLSRRKQVVAAALRQALQLDGDLQEDEIPVVAIMATGGGIRAMTSLYGQLAGLKELGLLDCVSYITGASGSTWALANLYEDPEWSQKDLAGPTELLKTQVTKNKLGVLAPSQLQRYRQELAERARLGYPSCFTNLWALINEALLHDEPHDHKLSDQREALSHGQNPLPIYCALNTKGQSLTTFEFGEWCEFSPYEVGFPKYGAFIPSELFGSEFFMGQLMKRLPESRICFLEGIWSNLYAANLQDSLYWASEPSQFWDRWVRNQANLDKEQVPLLKIEEPPSTAGRIAEFFTDLLTWRPLAQATHNFLRGLHFHKDYFQHPHFSTWKATTLDGLPNQLTPSEPHLCLLDVGYLINTSCLPLLQPTRDVDLILSLDYNLHGAFQQLQLLGRFCQEQGIPFPPISPSPEEQLQPRECHTFSDPTCPGAPAVLHFPLVSDSFREYSAPGVRRTPEEAAAGEVNLSSSDSPYHYTKVTYSQEDVDKLLHLTHYNVCNNQEQLLEALRQAVQRRRQRRPH

Target ORF information:

RefSeq Version	NM_005090.3
Organism	Homo sapiens(human)
Definition	Homo sapiens JMJD7-PLA2G4B readthrough (JMJD7-PLA2G4B), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_005090.3

ORF Insert Sequence:

ATGGCGGAGG CGGCTTTGGA AGCCGTGCGG AGCGAGTTAC GAGAATTCCC GGCCGCTGCA 
AGGGAGCTCT GCGTGCCTCT TGCTGTGCCC TACCTGGACA AACCCCCAAC TCCGCTCCAC 
TTCTACCGGG ACTGGGTCTG CCCCAACAGG CCGTGCATTA TCCGCAACGC TCTGCAGCAC 
TGGCCGGCCC TCCAGAAGTG GTCCCTCCCC TATTTCAGAG CCACAGTGGG CTCCACAGAG 
GTGAGTGTGG CCGTGACCCC AGATGGTTAC GCGGATGCCG TGAGAGGGGA TCGCTTCATG 
ATGCCAGCTG AGCGCCGCCT GCCCCTGAGC TTCGTGCTGG ATGTGCTGGA GGGCCGGGCC 
CAGCACCCTG GAGTCCTCTA TGTGCAGAAG CAGTGCTCCA ACCTGCCCAG CGAGCTGCCC 
CAGCTGCTGC CTGATCTGGA ATCCCATGTG CCCTGGGCCT CCGAAGCCCT GGGAAAGATG 
CCCGATGCTG TGAACTTCTG GCTGGGGGAG GCGGCTGCAG TGACTTCTTT GCACAAGGAC 
CACTATGAGA ACCTCTACTG CGTGGTCTCA GGAGAGAAGC ATTTCCTGTT CCATCCGCCC 
AGCGACCGGC CCTTCATCCC CTATGAGCTG TACACGCCGG CAACCTACCA GCTAACTGAA 
GAGGGCACCT TTAAGGTGGT GGATGAAGAG GCCATGGAGA AGGCAGAGGT GTCCAGGACC 
TGCCTGCTCA CGGTTCGTGT CCTGCAGGCC CATCGCCTAC CCTCTAAGGA CCTAGTGACC 
CCCTCTGACT GCTACGTGAC TCTCTGGCTG CCCACGGCCT GCAGCCACAG GCTCCAGACA 
CGCACGGTCA AGAACAGCAG TAGCCCTGTC TGGAACCAGA GCTTTCACTT CAGGATCCAC 
AGGCAGCTCA AGAATGTCAT GGAACTGAAA GTCTTTGACC AGGACCTGGT GACCGGAGAT 
GACCCTGTGT TGTCAGTACT GTTTGATGCG GGGACTCTGC GGGCTGGGGA GTTCCGGCGC 
GAGAGCTTCT CACTGAGCCC TCAGGGTGAG GGGCGCCTGG AAGTTGAATT TCGCCTGCAG 
AGTCTGGCTG ACCGTGGCGA GTGGCTCGTC AGCAATGGCG TTCTGGTGGC CCGGGAGCTC 
TCCTGCTTGC ACGTTCAACT GGAGGAGACA GGAGACCAGA AGTCCTCAGA GCACAGAGTT 
CAGCTTGTGG TTCCTGGGTC CTGTGAGGGT CCGCAGGAGG CCTCTGTGGG CACTGGCACC 
TTCCGCTTCC ACTGCCCAGC CTGCTGGGAG CAGGAGCTGA GTATTCGCCT GCAGGATGCC 
CCCGAGGAGC AACTAAAGGC GCCACTGAGT GCCCTGCCCT CTGGTCAAGT GGTGAGGCTT 
GTCTTCCCCA CGTCCCAGGA GCCCCTGATG AGAGTGGAGC TGAAAAAAGA AGCAGGACTG 
AGGGAGCTGG CCGTGCGACT GGGCTTCGGG CCCTGTGCAG AGGAGCAGGC CTTCCTGAGC 
AGGAGGAAGC AGGTGGTGGC CGCGGCCTTG AGGCAGGCCC TGCAGCTGGA CGGAGACCTG 
CAGGAGGATG AGATCCCAGT GGTAGCTATT ATGGCCACTG GTGGTGGGAT CCGGGCAATG 
ACTTCCCTGT ATGGGCAGCT GGCTGGCCTG AAGGAGCTGG GCCTCTTGGA TTGCGTCTCC 
TACATCACCG GGGCCTCGGG CTCCACCTGG GCCTTGGCCA ACCTTTATGA GGACCCAGAG 
TGGTCTCAGA AGGACCTGGC AGGGCCCACT GAGTTGCTGA AGACCCAGGT GACCAAGAAC 
AAGCTGGGTG TGCTGGCCCC CAGCCAGCTG CAGCGGTACC GGCAGGAGCT GGCCGAGCGT 
GCCCGCTTGG GCTACCCAAG CTGCTTCACC AACCTGTGGG CCCTCATCAA CGAGGCGCTG 
CTGCATGATG AGCCCCATGA TCACAAGCTC TCAGATCAAC GGGAGGCCCT GAGTCATGGC 
CAGAACCCTC TGCCCATCTA CTGTGCCCTC AACACCAAAG GGCAGAGCCT GACCACTTTT 
GAATTTGGGG AGTGGTGCGA GTTCTCTCCC TACGAGGTCG GCTTCCCCAA GTACGGGGCC 
TTCATCCCCT CTGAGCTCTT TGGCTCCGAG TTCTTTATGG GGCAGCTGAT GAAGAGGCTT 
CCTGAGTCCC GCATCTGCTT CTTAGAAGGT ATCTGGAGCA ACCTGTATGC AGCCAACCTC 
CAGGACAGCT TATACTGGGC CTCAGAGCCC AGCCAGTTCT GGGACCGCTG GGTCAGGAAC 
CAGGCCAACC TGGACAAGGA GCAGGTCCCC CTTCTGAAGA TAGAAGAACC ACCCTCAACA 
GCCGGCAGGA TAGCTGAGTT TTTCACCGAT CTTCTGACGT GGCGTCCACT GGCCCAGGCC 
ACACATAATT TCCTGCGTGG CCTCCATTTC CACAAAGACT ACTTTCAGCA TCCTCACTTC 
TCCACATGGA AAGCTACCAC TCTGGATGGG CTCCCCAACC AGCTGACACC CTCGGAGCCC 
CACCTGTGCC TGCTGGATGT TGGCTACCTC ATCAATACCA GCTGCCTGCC CCTCCTGCAG 
CCCACTCGGG ACGTGGACCT CATCCTGTCA TTGGACTACA ACCTCCACGG AGCCTTCCAG 
CAGTTGCAGC TCCTGGGCCG GTTCTGCCAG GAGCAGGGGA TCCCGTTCCC ACCCATCTCG 
CCCAGCCCCG AAGAGCAGCT CCAGCCTCGG GAGTGCCACA CCTTCTCCGA CCCCACCTGC 
CCCGGAGCCC CTGCGGTGCT GCACTTTCCT CTGGTCAGCG ACTCCTTCCG GGAGTACTCG 
GCCCCTGGGG TCCGGCGGAC ACCCGAGGAG GCGGCAGCTG GGGAGGTGAA CCTGTCTTCA 
TCGGACTCTC CCTACCACTA CACGAAGGTG ACCTACAGCC AGGAGGACGT GGACAAGCTG 
CTGCACCTGA CACATTACAA TGTCTGCAAC AACCAGGAGC AGCTGCTGGA GGCTCTGCGC 
CAGGCAGTGC AGCGGAGGCG GCAGCGCAGG CCCCACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Expression of conjoined genes: another mechanism for gene regulation in eukaryotes.
PloS one5(10)e13284(2010 Oct)
Prakash T,Sharma VK,Adati N,Ozawa R,Kumar N,Nishida Y,Fujikake T,Takeda T,Taylor TD

Identification of the expressed form of human cytosolic phospholipase A2beta (cPLA2beta): cPLA2beta3 is a novel variant localized to mitochondria and early endosomes.
The Journal of biological chemistry281(24)16615-24(2006 Jun)
Ghosh M,Loper R,Gelb MH,Leslie CC

Cytosolic PLA2 genes possibly contribute to the etiology of schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics137B(1)56-8(2005 Aug)
Tao R,Yu Y,Zhang X,Guo Y,Shi J,Zhang X,Xie L,Liu S,Ju G,Xu Q,Shen Y,Wei J

Association analysis of two candidate phospholipase genes that map to the chromosome 15q15.1-15.3 region associated with reading disability.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics129B(1)97-103(2004 Aug)
Morris DW,Ivanov D,Robinson L,Williams N,Stevenson J,Owen MJ,Williams J,O'Donovan MC

Groups IV, V, and X phospholipases A2s in human neutrophils: role in eicosanoid production and gram-negative bacterial phospholipid hydrolysis.
The Journal of biological chemistry277(7)5061-73(2002 Feb)
Degousee N,Ghomashchi F,Stefanski E,Singer A,Smart BP,Borregaard N,Reithmeier R,Lindsay TF,Lichtenberger C,Reinisch W,Lambeau G,Arm J,Tischfield J,Gelb MH,Rubin BB

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JMJD7-PLA2G4B cDNA ORF clone, Homo sapiens(human)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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