ARHGAP11B cDNA ORF clone, Homo sapiens(human)
| Gene Symbol | ARHGAP11B |
| Entrez Gene ID | 89839 |
| Full Name | Rho GTPase activating protein 11B |
| Synonyms | B'-T,FAM7B1,GAP (1-8) |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Disorder MIM: |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_001039841.1 | NP_001034930.1 | rho GTPase-activating protein 11B |
| NM_001039841.2 | NP_001034930.1 | rho GTPase-activating protein 11B |
Related articles in PubMed
A single splice site mutation in human-specific
Florio M, Namba T, P??bo S, Hiller M, Huttner WB
Science advances2(12)e1601941(2016 Dec)
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion.
Florio M, Albert M, Taverna E, Namba T, Brandl H, Lewitus E, Haffner C, Sykes A, Wong FK, Peters J, Guhr E, Klemroth S, Pr?fer K, Kelso J, Naumann R, N?sslein I, Dahl A, Lachmann R, P??bo S, Huttner WB
Science (New York, N.Y.)347(6229)1465-70(2015 Mar)
A genome-wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy.
Speed D, Hoggart C, Petrovski S, Tachmazidou I, Coffey A, Jorgensen A, Eleftherohorinou H, De Iorio M, Todaro M, De T, Smith D, Smith PE, Jackson M, Cooper P, Kellett M, Howell S, Newton M, Yerra R, Tan M, French C, Reuber M, Sills GE, Chadwick D, Pirmohamed M, Bentley D, Scheffer I, Berkovic S, Balding D, Palotie A, Marson A, O'Brien TJ, Johnson MR
Human molecular genetics23(1)247-58(2014 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
ARHGAP11B may have contributed to evolutionary expansion of human neocortex.
Title: Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion.
The following ARHGAP11B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ARHGAP11B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OHu13447 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001039841.1 , NM_001039841.2 | |
| Accession Version | NM_001039841.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 804bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2015-04-10 | |
| Organism | Homo sapiens(Human) | |
| Product | rho GTPase-activating protein 11B | |
| Comment | PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC105788.1. On or before Mar 17, 2006 this sequence version replaced XM_931017.1, XM_931023.1, XM_931028.1, XM_926156.1, XM_931039.1, XM_931045.1, XM_931050.1. ##Evidence-Data-START## Transcript exon combination :: BC105788.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGTGGGATC AGAGGCTGGT GAAGTTGGCC CTGTTGCAGC ATCTGCGGGC CTTCTATGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001034930.1 |
| CDS | 146..949 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001039841.1 |
ORF Insert Sequence:
1 | ATGTGGGATC AGAGGCTGGT GAAGTTGGCC CTGTTGCAGC ATCTGCGGGC CTTCTATGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu13447 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_001039841.1 , NM_001039841.2 | |
| Accession Version | NM_001039841.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 804bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-30 | |
| Organism | Homo sapiens(human) | |
| Product | rho GTPase-activating protein 11B | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL556699.3, AC091057.6 and BC105788.1. On Jul 12, 2017 this sequence version replaced NM_001039841.1. Transcript Variant: This variant (1) represents the protein-coding transcript. ##Evidence-Data-START## Transcript exon combination :: BC105788.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGTGGGATC AGAGGCTGGT GAAGTTGGCC CTGTTGCAGC ATCTGCGGGC CTTCTATGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001034930.1 |
| CDS | 674..1477 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001039841.2 |
ORF Insert Sequence:
1 | ATGTGGGATC AGAGGCTGGT GAAGTTGGCC CTGTTGCAGC ATCTGCGGGC CTTCTATGGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
A single splice site mutation in human-specific |
|
Human-specific gene ARHGAP11B promotes basal progenitor amplification and neocortex expansion. |
|
A genome-wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy. |