Gene Symbol | CD22 |
Entrez Gene ID | 933 |
Full Name | CD22 molecule |
Synonyms | SIGLEC-2,SIGLEC2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » CD22 cDNA ORF clone
Gene Symbol | CD22 |
Entrez Gene ID | 933 |
Full Name | CD22 molecule |
Synonyms | SIGLEC-2,SIGLEC2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_001185100.1 | NP_001172029.1 | B-cell receptor CD22 isoform 3 precursor |
NM_001771.4 | NP_001762.2 | B-cell receptor CD22 isoform 1 precursor |
NM_001278417.2 | NP_001265346.1 | B-cell receptor CD22 isoform 5 |
NM_001185100.2 | NP_001172029.1 | B-cell receptor CD22 isoform 3 precursor |
NM_001185099.1 | NP_001172028.1 | B-cell receptor CD22 isoform 2 precursor |
NM_001278417.1 | NP_001265346.1 | B-cell receptor CD22 isoform 5 |
NM_001185101.1 | NP_001172030.1 | B-cell receptor CD22 isoform 4 precursor |
NM_001771.3 | NP_001762.2 | B-cell receptor CD22 isoform 1 precursor |
NM_001185099.2 | NP_001172028.1 | B-cell receptor CD22 isoform 2 precursor |
Homo sapiens (human) | CD22 | NP_001762.2 |
Bos taurus (cattle) | CD22 | XP_002695061.3 |
Pan troglodytes (chimpanzee) | CD22 | XP_001159578.1 |
Canis lupus familiaris (dog) | CD22 | XP_867891.1 |
Mus musculus (house mouse) | Cd22 | NP_001036782.1 |
Rattus norvegicus (Norway rat) | Cd22 | NP_001100973.1 |
Xenopus tropicalis (tropical clawed frog) | cd22 | XP_002938259.2 |
Human CD22 Inhibits Murine B Cell Receptor Activation in a Human CD22 Transgenic Mouse Model.
Bednar KJ, Shanina E, Ballet R, Connors EP, Duan S, Juan J, Arlian BM, Kulis MD, Butcher EC, Fung-Leung WP, Rao TS, Paulson JC, Macauley MS
Journal of immunology (Baltimore, Md. : 1950)199(9)3116-3128(2017 Nov)
Molecular basis of human CD22 function and therapeutic targeting.
Ere?o-Orbea J, Sicard T, Cui H, Mazhab-Jafari MT, Benlekbir S, Guarn? A, Rubinstein JL, Julien JP
Nature communications8(1)764(2017 10)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
hCD22 transgenic mice develop normal humoral responses in a peanut allergy oral sensitization model. Homing of B cells to Peyer's patches was partially rescued by expression of hCD22 compared with CD22(-/-) B cells, although not to wild-type levels.
Title: Human CD22 Inhibits Murine B Cell Receptor Activation in a Human CD22 Transgenic Mouse Model.
Here the authors structurally characterize the ectodomain of CD22 and present its crystal structure with the bound therapeutic antibody epratuzumab, which gives insights into the mechanism of inhibition of B-cell activation.
Title: Molecular basis of human CD22 function and therapeutic targeting.
Diabody-based (177)Lu-radioimmunoconjugate for CD22-directed radioimmunotherapy reduced disease burden in a non-Hodgkin lymphoma mouse model.
Title: Preclinical evaluation of a diabody-based (177)Lu-radioimmunoconjugate for CD22-directed radioimmunotherapy in a non-Hodgkin lymphoma mouse model.
We aimed to screen exons 9-14 of the CD22 gene, which is a mutational hot spot region in B-precursor acute lymphoblastic leukemia (pre-B ALL) patients. Nine variants, of which two novel, were found. Novel variants were in introns 10 and 13. Gly745Asp (rs10406069) variant was missense and Cys790Arg (rs79438722) variant was silent.
Title: Screening of Variations in CD22 Gene in Children with B-Precursor Acute Lymphoblastic Leukemia.
Siglec-1 and Siglec-2 are potential biomarkers in autoimmune disease. (Review)
Title: Siglec-1 and -2 as potential biomarkers in autoimmune disease.
The following CD22 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CD22 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu01129 | |
Clone ID Related Accession (Same CDS sequence) | NM_001771.4 , NM_001771.3 | |
Accession Version | NM_001771.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2544bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-27 | |
Organism | Homo sapiens(human) | |
Product | B-cell receptor CD22 isoform 1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK225625.1, AK225694.1, BC109306.1, DB333800.1 and X59350.1. On Nov 22, 2018 this sequence version replaced NM_001771.3. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK225694.1, X59350.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000085219.10/ ENSP00000085219.4 RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGCATCTCC TCGGCCCCTG GCTCCTGCTC CTGGTTCTAG AATACTTGGC TTTCTCTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001762.2 |
CDS | 67..2610 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001771.4 |
1 | ATGCATCTCC TCGGCCCCTG GCTCCTGCTC CTGGTTCTAG AATACTTGGC TTTCTCTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu01129 | |
Clone ID Related Accession (Same CDS sequence) | NM_001771.4 , NM_001771.3 | |
Accession Version | NM_001771.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2544bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-11-26 | |
Organism | Homo sapiens(human) | |
Product | B-cell receptor CD22 isoform 1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA989528.1, AK225625.1, AK225694.1, BC109306.1, DB333800.1 and X59350.1. On Jun 3, 2010 this sequence version replaced NM_001771.2. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X59350.1, AK225694.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCATCTCC TCGGCCCCTG GCTCCTGCTC CTGGTTCTAG AATACTTGGC TTTCTCTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001762.2 |
CDS | 85..2628 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001771.3 |
1 | ATGCATCTCC TCGGCCCCTG GCTCCTGCTC CTGGTTCTAG AATACTTGGC TTTCTCTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu00934 | |
Clone ID Related Accession (Same CDS sequence) | NM_001185101.1 | |
Accession Version | NM_001185101.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2013bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-27 | |
Organism | Homo sapiens(human) | |
Product | B-cell receptor CD22 isoform 4 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA989528.1, X52785.1, BC109306.1, DB333800.1 and X59350.1. Transcript Variant: This variant (4) lacks an alternate in-frame segment compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X52785.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCATCTCC TCGGCCCCTG GCTCCTGCTC CTGGTTCTAG AATACTTGGC TTTCTCTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001172030.1 |
CDS | 85..2097 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001185101.1 |
1 | ATGCATCTCC TCGGCCCCTG GCTCCTGCTC CTGGTTCTAG AATACTTGGC TTTCTCTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu01137 | |
Clone ID Related Accession (Same CDS sequence) | NM_001278417.2 , NM_001278417.1 | |
Accession Version | NM_001278417.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2028bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-27 | |
Organism | Homo sapiens(human) | |
Product | B-cell receptor CD22 isoform 5 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CF138699.1, BC109306.1, U62631.2, BQ054599.1 and KC877723.1. On May 31, 2019 this sequence version replaced NM_001278417.1. Transcript Variant: This variant (5) lacks the exon containing the translation initiation site and uses an alternate splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (5) has a shorter and distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC109306.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCTCTGT GGCTCCTAGA GGGGGTTCCA ATGAGGCAGG CTGCTGTCAC CTCGACCTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001265346.1 |
CDS | 408..2435 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001278417.2 |
1 | ATGTCTCTGT GGCTCCTAGA GGGGGTTCCA ATGAGGCAGG CTGCTGTCAC CTCGACCTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu01137 | |
Clone ID Related Accession (Same CDS sequence) | NM_001278417.2 , NM_001278417.1 | |
Accession Version | NM_001278417.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2028bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-12-15 | |
Organism | Homo sapiens(human) | |
Product | B-cell receptor CD22 isoform 5 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CF138699.1, BC109306.1, U62631.2 and BQ054599.1. Transcript Variant: This variant (5) lacks the exon containing the translation initiation site and uses an alternate splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (5) has a shorter and distinct N-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC109306.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCTCTGT GGCTCCTAGA GGGGGTTCCA ATGAGGCAGG CTGCTGTCAC CTCGACCTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001265346.1 |
CDS | 429..2456 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001278417.1 |
1 | ATGTCTCTGT GGCTCCTAGA GGGGGTTCCA ATGAGGCAGG CTGCTGTCAC CTCGACCTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu04885 | |
Clone ID Related Accession (Same CDS sequence) | NM_001185099.1 , NM_001185099.2 | |
Accession Version | NM_001185099.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2280bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-12-09 | |
Organism | Homo sapiens(human) | |
Product | B-cell receptor CD22 isoform 2 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA989528.1, AK225625.1, AK225694.1 and X59350.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK225625.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCATCTCC TCGGCCCCTG GCTCCTGCTC CTGGTTCTAG AATACTTGGC TTTCTCTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001172028.1 |
CDS | 85..2364 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001185099.1 |
1 | ATGCATCTCC TCGGCCCCTG GCTCCTGCTC CTGGTTCTAG AATACTTGGC TTTCTCTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu04885 | |
Clone ID Related Accession (Same CDS sequence) | NM_001185099.1 , NM_001185099.2 | |
Accession Version | NM_001185099.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2280bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-27 | |
Organism | Homo sapiens(human) | |
Product | B-cell receptor CD22 isoform 2 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK225625.1, AK225694.1 and X59350.1. On May 31, 2019 this sequence version replaced NM_001185099.1. Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK225625.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCATCTCC TCGGCCCCTG GCTCCTGCTC CTGGTTCTAG AATACTTGGC TTTCTCTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001172028.1 |
CDS | 67..2346 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001185099.2 |
1 | ATGCATCTCC TCGGCCCCTG GCTCCTGCTC CTGGTTCTAG AATACTTGGC TTTCTCTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu07886 | |
Clone ID Related Accession (Same CDS sequence) | NM_001185100.1 , NM_001185100.2 | |
Accession Version | NM_001185100.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2256bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-21 | |
Organism | Homo sapiens(human) | |
Product | B-cell receptor CD22 isoform 3 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA989528.1, BC109307.1, U62631.2, BC109306.1, DB333800.1 and X59350.1. Transcript Variant: This variant (3) lacks an alternate coding exon compared to variant 1, that causes a frameshift. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC109307.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCATCTCC TCGGCCCCTG GCTCCTGCTC CTGGTTCTAG AATACTTGGC TTTCTCTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001172029.1 |
CDS | 85..2340 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001185100.1 |
1 | ATGCATCTCC TCGGCCCCTG GCTCCTGCTC CTGGTTCTAG AATACTTGGC TTTCTCTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu07886 | |
Clone ID Related Accession (Same CDS sequence) | NM_001185100.1 , NM_001185100.2 | |
Accession Version | NM_001185100.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2256bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-27 | |
Organism | Homo sapiens(human) | |
Product | B-cell receptor CD22 isoform 3 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA989528.1, BC109307.1, U62631.2, BC109306.1, DB333800.1 and X59350.1. On May 31, 2019 this sequence version replaced NM_001185100.1. Transcript Variant: This variant (3) lacks an alternate coding exon compared to variant 1, that causes a frameshift. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC109307.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCATCTCC TCGGCCCCTG GCTCCTGCTC CTGGTTCTAG AATACTTGGC TTTCTCTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001172029.1 |
CDS | 67..2322 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001185100.2 |
1 | ATGCATCTCC TCGGCCCCTG GCTCCTGCTC CTGGTTCTAG AATACTTGGC TTTCTCTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Human CD22 Inhibits Murine B Cell Receptor Activation in a Human CD22 Transgenic Mouse Model. |
Molecular basis of human CD22 function and therapeutic targeting. |