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LRIG2 cDNA ORF clone, Homo sapiens(human)

Summary

Gene Symbol LRIG2
Entrez Gene ID 9860
Full Name leucine rich repeats and immunoglobulin like domains 2
Synonyms LIG-2,LIG2,UFS2
General protein information
Preferred Names

leucine rich repeats and immunoglobulin like domains 2

Names

leucine-rich repeats and immunoglobulin-like domains protein 2
Gene Type protein-coding
Organism Homo sapiens(human)
Genome

1

1p13.2
Summary This gene encodes a transmembrane protein containing leucine-rich repeats and immunoglobulin-like domains. The encoded protein promotes epidermal growth factor signalling, resulting in increased proliferation. Its expression in the cytoplasm of glioma cells is correlated with poor survival. Mutations in this gene can cause urofacial syndrome. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2015].
Disorder MIM:

608869

Disorder Html: Urofacial syndrome 2, 615112 (3)

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_001312686.1 NP_001299615.1 leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 2
XM_005271369.2 XP_005271426.1 leucine-rich repeats and immunoglobulin-like domains protein 2 isoform X1
NM_014813.2 NP_055628.1 leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor
XM_017002952.1 XP_016858441.1 leucine-rich repeats and immunoglobulin-like domains protein 2 isoform X2

Pathways from BioSystems


Homologies


Homo sapiens (human) LRIG2 NP_055628.1
Rattus norvegicus (Norway rat) Lrig2 NP_001101180.1
Xenopus tropicalis (tropical clawed frog) lrig2 XP_002932176.2
LRIG2 XP_002801776.1
Gallus gallus (chicken) LRIG2 XP_004935054.1
Danio rerio (zebrafish) lrig2 XP_699750.6
Bos taurus (cattle) LRIG2 NP_001179789.1
Canis lupus familiaris (dog) LRIG2 XP_540333.3
Mus musculus (house mouse) Lrig2 NP_001020238.1

Gene Ontology


Bibliography

Related articles in PubMed

LRIGs: A Prognostically Significant Family with Emerging Therapeutic Competence against Cancers.
Malik U, Javed A
Current cancer drug targets17(1)3-16(2017)

LRIG and cancer prognosis.
Lindquist D, Kvarnbrink S, Henriksson R, Hedman H
Acta oncologica (Stockholm, Sweden)53(9)1135-42(2014 Sep)

LRIG2 expression and prognosis in non-small cell lung cancer.
Wang G, Wu J, Song H
Oncology letters8(2)667-672(2014 Aug)

Soluble LRIG2 ectodomain is released from glioblastoma cells and promotes the proliferation and inhibits the apoptosis of glioblastoma cells in vitro and in vivo in a similar manner to the full-length LRIG2.
Xiao Q, Tan Y, Guo Y, Yang H, Mao F, Xie R, Wang B, Lei T, Guo D
PloS one9(10)e111419(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Role of LRIG2 in cancer [review]
Title: LRIGs: A Prognostically Significant Family with Emerging Therapeutic Competence against Cancers.

A subset of urofacial syndrome-affected individuals have biallelic mutations in LRIG2
Title: LRIG2 mutations cause urofacial syndrome.

Cytoplasmic expression of LRIG2 is associated with meningiomas.
Title: Immunohistochemical analysis of LRIG proteins in meningiomas: correlation between estrogen receptor status and LRIG expression.

LRIG2 gene is overexpressed in invasive pituitary adenoma.
Title: Association of expression of Leucine-rich repeats and immunoglobulin-like domains 2 gene with invasiveness of pituitary adenoma.

LRIG1 and LRIG2 expressions were seen in precancerous cervical epithelium and found to increase with increasing grade.
Title: Correlation between LRIG1 and LRIG2 expressions and expression of 11 tumor markers, with special reference to tumor suppressors, in CIN and normal cervical epithelium.

The following LRIG2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the LRIG2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OHu63399 NM_001312686.1
Latest version!		 Homo sapiens leucine rich repeats and immunoglobulin like domains 2 (LRIG2), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $475.30
$679.00
OHu34014 XM_005271369.2
Latest version!		 Homo sapiens leucine-rich repeats and immunoglobulin like domains 2 (LRIG2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 12-14 $475.30
$679.00
OHu90879 XM_017002952.1
Latest version!		 Homo sapiens leucine-rich repeats and immunoglobulin like domains 2 (LRIG2), transcript variant X2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 14-16 $307.30
$439.00
OHu63398 NM_014813.2
Latest version!		 Homo sapiens leucine rich repeats and immunoglobulin like domains 2 (LRIG2), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 20 $559.30
$799.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OHu63399
Clone ID Related Accession (Same CDS sequence) NM_001312686.1
Accession Version NM_001312686.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2889bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-16
Organism Homo sapiens(human)
Product leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 2
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA506094.1, CR936669.1, AL357055.18 and AB018349.1. Transcript Variant: This variant (2) contains an alternate exon in the 5' region and initiates translation at a downstream start codon, compared to variant 1. The encoded isoform (2) has a shorter N-terminus than isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CR936669.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03465413 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

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ATGAATTACA ATGAACTAAC AGAAATCCCG TATTTTGGAG AACCTACATC TAATATTACT 
CTACTTTCAT TAGTCCATAA TATAATCCCA GAAATAAATG CACAGGCACT CCAGTTTTAC 
CCTGCTCTGG AGAGTTTAGA CCTCAGCTCA AATATAATAT CAGAAATCAA GACATCTTCA 
TTTCCTCGCA TGCAGCTTAA ATACCTGAAT TTAAGTAATA ACAGAATAAC CACCTTGGAG 
GCTGGTTGCT TCGATAATTT ATCAAGTTCC TTATTAGTGG TAAAGTTAAA CCGTAACCGA 
ATGAGCATGA TTCCACCTAA GATCTTCAAG CTGCCTCACC TCCAATTCTT GGAACTTAAA 
AGAAACAGAA TTAAAATTGT GGAAGGTCTT ACATTCCAAG GGCTTGACTC CTTAAGATCT 
TTGAAAATGC AGCGGAATGG AATTAGCAAA CTTAAGGATG GAGCATTTTT TGGCTTGAAT 
AACATGGAAG AACTAGAACT GGAACACAAC AACCTTACAC GAGTAAACAA GGGGTGGTTG 
TATGGCTTGC GAATGTTACA GCAGCTCTAT GTGAGCCAGA ATGCTATTGA AAGAATCAGC 
CCTGATGCAT GGGAGTTCTG CCAAAGACTA TCCGAACTTG ATTTGTCCTA TAACCAGCTG 
ACCCGCCTGG ATGAATCTGC CTTTGTGGGT CTGAGCTTAT TGGAGAGATT GAATTTAGGA 
GACAACAGAG TCACTCATAT TGCTGATGGT GTATTTAGAT TTCTTTCCAA TCTTCAGACA 
TTAGACTTAA GAAACAATGA AATTTCATGG GCCATAGAAG ATGCTAGTGA AGCCTTTGCT 
GGACTCACAA GTCTCACTAA ACTAATCTTA CAAGGAAACC AGATTAAGTC AATTACAAAG 
AAAGCATTCA TTGGTCTTGA ATCCCTTGAG CATCTAGATT TGAACAATAA TGCTATAATG 
TCTATCCAAG AAAATGCTTT TTCTCAGACT CATTTAAAAG AACTGATTCT GAACACAAGC 
AGTTTGCTCT GTGACTGCCA TTTGAAGTGG CTACTTCAAT GGTTGGTTGA TAATAACTTT 
CAACATTCTG TGAATGTAAG CTGTGCACAC CCTGAATGGC TAGCAGGGCA AAGCATCCTG 
AATGTGGATC TGAAAGATTT TGTCTGTGAT GATTTTCTCA AGCCACAGAT AAGGACACAT 
CCTGAAACCA TAATTGCTCT AAGAGGCATG AATGTGACTC TGACGTGCAC TGCAGTGAGC 
AGCAGTGATT CACCCATGTC CACTGTGTGG CGCAAAGACA GTGAAATCCT GTATGACGTG 
GATACTGAGA ATTTTGTTCG TTATTGGCAG CAAGCTGGAG AAGCTCTGGA ATATACTAGT 
ATCTTACATC TTTTCAATGT GAATTTCACA GATGAAGGAA AATATCAGTG TATTGTTACT 
AATCACTTTG GTTCTAATTA TTCTCAGAAA GCCAAACTGA CTGTAAATGA GATGCCATCT 
TTTCTGAAAA CGCCAATGGA TCTGACTATT CGCACTGGTG CCATGGCCAG ATTAGAATGT 
GCTGCAGAGG GACACCCTGC ACCTCAGATT TCCTGGCAGA AAGATGGTGG TACTGACTTT 
CCTGCGGCTC GAGAAAGACG CATGCACGTC ATGCCCGAGG ATGACGTCTT CTTTATTGCC 
AATGTGAAAA TAGAAGATAT GGGAATCTAT AGCTGCATGG CACAAAATAC AGCAGGAGGT 
CTCTCAGCAA ATGCTTCCCT AACAGTGTTA GAGACACCCT CATTTATTAG ACCCCTGGAG 
GATAAGACAG TAACACGAGG TGAAACTGCG GTGTTACAGT GCATAGCTGG AGGGAGTCCT 
GCCCCTCGTC TCAACTGGAC TAAAGATGAT GGGCCTTTGC TGGTGACAGA ACGACATTTC 
TTTGCTGCAG CCAATCAGCT TCTCATCATT GTAGATGCCG GGCTAGAAGA TGCTGGGAAA 
TATACCTGCA TTATGTCTAA CACCCTTGGG ACAGAACGTG GCCACATTTA CCTAAATGTC 
ATTTCATCCC CCAATTGTGA CTCTTCCCAG AGTAGCATTG GGCATGAAGA TGATGGCTGG 
ACCACAGTTG GCATTGTCAT CATTGTTGTG GTCTGCTGTG TTGTTGGCAC TTCTTTGATC 
TGGGTCATTG TTATTTACCA CATGAGAAGG AAAAATGAAG ACTATAGTAT CACAAACACA 
GAGGAGCTCA ATCTGCCTGC AGACATTCCC AGCTACTTGT CTTCCCAAGG AACGCTGTCT 
GAGCCACAGG AAGGCTACAG CAACTCTGAG GCAGGCAGTC ATCAGCAACT TATGCCTCCT 
GCCAATGGAT ATATACACAA AGGCACTGAC GGTGGCACTG GTACCCGGGT GATTTGCTCA 
GATTGTTATG ACAATGCCAA CATCTACTCC AGGACCCGAG AATACTGTCC ATACACCTAT 
ATTGCTGAGG AGGACGTTCT TGATCAGACA CTGTCCAGCC TCATGGTCCA AATGCCTAAA 
GAGACATATT TAGTACATCC TCCCCAGGAT ACTACTGCCC TAGAGAGCCT GATACCGTCA 
GCCAACAGAG AGCCATCTGC CTTTCCCACC AACCATGAGA GGATAAGTGA GAAGAAACTT 
CCCTCCACAC AGATGAGCGG TGAAACATTG CAGCGGCCCG TGTGGAACAT AAACAGAGAA 
CTAGGCCTGC CTCATCCTCC TTTTTCCCAG CAGCCAGTCC ATGAGTCACC ACAACTTCAT 
CAAAATGAGG GCCTGGCAGG GAGAGAGCCA GACTGTTCTG CTTCTTCCAT GTCCTGCCAC 
AGGTTACAGG ATCATGCTTT TGATTTTAGT AGGACTCGGA ACATTCAAGA TGGTAGTGAG 
GGCACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001299615.1
CDS659..3547
Misc Feature(1)644..646
Misc Feature(2)707..886
Misc Feature(3)713..784
Misc Feature(4)<758..1384
Misc Feature(5)785..853
Misc Feature(6)order(806..808,950..952,1019..1021,1163..1165,1226..1228,1232..1234,1298..1300,1370..1372)
Misc Feature(7)851..1102
Misc Feature(8)854..925
Misc Feature(9)929..997
Misc Feature(10)998..1069
Misc Feature(11)1067..1246
Misc Feature(12)1070..1141
Misc Feature(13)1142..1213
Misc Feature(14)1145..1825
Misc Feature(15)1214..1285
Misc Feature(16)1283..1462
Misc Feature(17)1286..1357
Misc Feature(18)1358..1429
Misc Feature(19)1424..1615
Misc Feature(20)1430..1504
Misc Feature(21)1511..1582
Misc Feature(22)1583..1651
Misc Feature(23)1682..1828
Misc Feature(24)1853..2143
Misc Feature(25)1859..2143
Misc Feature(26)2153..2425
Misc Feature(27)2204..2428
Misc Feature(28)2435..2698
Misc Feature(29)2489..2698
Exon (1)1..476
Exon (2)477..542
Exon (3)543..654
Exon (4)655..729
Exon (5)730..864
Exon (6)865..1008
Exon (7)1009..1152
Exon (8)1153..1296
Exon (9)1297..1440
Exon (10)1441..1521
Exon (11)1522..1593
Exon (12)1594..1662
Exon (13)1663..1826
Exon (14)1827..2147
Exon (15)2148..2429
Exon (16)2430..2879
Exon (17)2880..3029
Exon (18)3030..3320
Exon (19)3321..4648
Translation

Target ORF information:

RefSeq Version NM_001312686.1
Organism Homo sapiens(human)
Definition Homo sapiens leucine rich repeats and immunoglobulin like domains 2 (LRIG2), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001312686.1

ORF Insert Sequence:

1
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181
241
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421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
ATGAATTACA ATGAACTAAC AGAAATCCCG TATTTTGGAG AACCTACATC TAATATTACT 
CTACTTTCAT TAGTCCATAA TATAATCCCA GAAATAAATG CACAGGCACT CCAGTTTTAC 
CCTGCTCTGG AGAGTTTAGA CCTCAGCTCA AATATAATAT CAGAAATCAA GACATCTTCA 
TTTCCTCGCA TGCAGCTTAA ATACCTGAAT TTAAGTAATA ACAGAATAAC CACCTTGGAG 
GCTGGTTGCT TCGATAATTT ATCAAGTTCC TTATTAGTGG TAAAGTTAAA CCGTAACCGA 
ATGAGCATGA TTCCACCTAA GATCTTCAAG CTGCCTCACC TCCAATTCTT GGAACTTAAA 
AGAAACAGAA TTAAAATTGT GGAAGGTCTT ACATTCCAAG GGCTTGACTC CTTAAGATCT 
TTGAAAATGC AGCGGAATGG AATTAGCAAA CTTAAGGATG GAGCATTTTT TGGCTTGAAT 
AACATGGAAG AACTAGAACT GGAACACAAC AACCTTACAC GAGTAAACAA GGGGTGGTTG 
TATGGCTTGC GAATGTTACA GCAGCTCTAT GTGAGCCAGA ATGCTATTGA AAGAATCAGC 
CCTGATGCAT GGGAGTTCTG CCAAAGACTA TCCGAACTTG ATTTGTCCTA TAACCAGCTG 
ACCCGCCTGG ATGAATCTGC CTTTGTGGGT CTGAGCTTAT TGGAGAGATT GAATTTAGGA 
GACAACAGAG TCACTCATAT TGCTGATGGT GTATTTAGAT TTCTTTCCAA TCTTCAGACA 
TTAGACTTAA GAAACAATGA AATTTCATGG GCCATAGAAG ATGCTAGTGA AGCCTTTGCT 
GGACTCACAA GTCTCACTAA ACTAATCTTA CAAGGAAACC AGATTAAGTC AATTACAAAG 
AAAGCATTCA TTGGTCTTGA ATCCCTTGAG CATCTAGATT TGAACAATAA TGCTATAATG 
TCTATCCAAG AAAATGCTTT TTCTCAGACT CATTTAAAAG AACTGATTCT GAACACAAGC 
AGTTTGCTCT GTGACTGCCA TTTGAAGTGG CTACTTCAAT GGTTGGTTGA TAATAACTTT 
CAACATTCTG TGAATGTAAG CTGTGCACAC CCTGAATGGC TAGCAGGGCA AAGCATCCTG 
AATGTGGATC TGAAAGATTT TGTCTGTGAT GATTTTCTCA AGCCACAGAT AAGGACACAT 
CCTGAAACCA TAATTGCTCT AAGAGGCATG AATGTGACTC TGACGTGCAC TGCAGTGAGC 
AGCAGTGATT CACCCATGTC CACTGTGTGG CGCAAAGACA GTGAAATCCT GTATGACGTG 
GATACTGAGA ATTTTGTTCG TTATTGGCAG CAAGCTGGAG AAGCTCTGGA ATATACTAGT 
ATCTTACATC TTTTCAATGT GAATTTCACA GATGAAGGAA AATATCAGTG TATTGTTACT 
AATCACTTTG GTTCTAATTA TTCTCAGAAA GCCAAACTGA CTGTAAATGA GATGCCATCT 
TTTCTGAAAA CGCCAATGGA TCTGACTATT CGCACTGGTG CCATGGCCAG ATTAGAATGT 
GCTGCAGAGG GACACCCTGC ACCTCAGATT TCCTGGCAGA AAGATGGTGG TACTGACTTT 
CCTGCGGCTC GAGAAAGACG CATGCACGTC ATGCCCGAGG ATGACGTCTT CTTTATTGCC 
AATGTGAAAA TAGAAGATAT GGGAATCTAT AGCTGCATGG CACAAAATAC AGCAGGAGGT 
CTCTCAGCAA ATGCTTCCCT AACAGTGTTA GAGACACCCT CATTTATTAG ACCCCTGGAG 
GATAAGACAG TAACACGAGG TGAAACTGCG GTGTTACAGT GCATAGCTGG AGGGAGTCCT 
GCCCCTCGTC TCAACTGGAC TAAAGATGAT GGGCCTTTGC TGGTGACAGA ACGACATTTC 
TTTGCTGCAG CCAATCAGCT TCTCATCATT GTAGATGCCG GGCTAGAAGA TGCTGGGAAA 
TATACCTGCA TTATGTCTAA CACCCTTGGG ACAGAACGTG GCCACATTTA CCTAAATGTC 
ATTTCATCCC CCAATTGTGA CTCTTCCCAG AGTAGCATTG GGCATGAAGA TGATGGCTGG 
ACCACAGTTG GCATTGTCAT CATTGTTGTG GTCTGCTGTG TTGTTGGCAC TTCTTTGATC 
TGGGTCATTG TTATTTACCA CATGAGAAGG AAAAATGAAG ACTATAGTAT CACAAACACA 
GAGGAGCTCA ATCTGCCTGC AGACATTCCC AGCTACTTGT CTTCCCAAGG AACGCTGTCT 
GAGCCACAGG AAGGCTACAG CAACTCTGAG GCAGGCAGTC ATCAGCAACT TATGCCTCCT 
GCCAATGGAT ATATACACAA AGGCACTGAC GGTGGCACTG GTACCCGGGT GATTTGCTCA 
GATTGTTATG ACAATGCCAA CATCTACTCC AGGACCCGAG AATACTGTCC ATACACCTAT 
ATTGCTGAGG AGGACGTTCT TGATCAGACA CTGTCCAGCC TCATGGTCCA AATGCCTAAA 
GAGACATATT TAGTACATCC TCCCCAGGAT ACTACTGCCC TAGAGAGCCT GATACCGTCA 
GCCAACAGAG AGCCATCTGC CTTTCCCACC AACCATGAGA GGATAAGTGA GAAGAAACTT 
CCCTCCACAC AGATGAGCGG TGAAACATTG CAGCGGCCCG TGTGGAACAT AAACAGAGAA 
CTAGGCCTGC CTCATCCTCC TTTTTCCCAG CAGCCAGTCC ATGAGTCACC ACAACTTCAT 
CAAAATGAGG GCCTGGCAGG GAGAGAGCCA GACTGTTCTG CTTCTTCCAT GTCCTGCCAC 
AGGTTACAGG ATCATGCTTT TGATTTTAGT AGGACTCGGA ACATTCAAGA TGGTAGTGAG 
GGCACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu34014
Clone ID Related Accession (Same CDS sequence) XM_005271369.2
Accession Version XM_005271369.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 2877bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(human)
Product leucine-rich repeats and immunoglobulin-like domains protein 2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_005271369.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

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2641
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ATGGCGCCGG CGCCCCTAGG CGTCCCGGAG GAGCAGTTGC TGGGGTGTCG ATCTAGAGTG 
CTTTCTCGGT TACTCTTCAT TGCCCAGACC GCTCTCCTCC TGTTGCCCGC CGCCGGAGCA 
GGTCTCTGCC CCGCGCCCTG CTCCTGCCGC ATTCCTCTCC TGGACTGCAG TCGCAGGAAA 
TTGCCCGCAC CGAGCTGGAG GGCGCTGTCG GGCTTGCTGC CCCCCGACAC CGCTATCCTG 
GATTTCAGTC ATAATCGGTT GTCTAACTGG AACATCAGCT TGGAATCACA AACATTACAG 
GAAGTGAAAA TGAATTACAA TGAACTAACA GAAATCCCGT ATTTTGGAGA ACCTACATCT 
AATATTACTC TACTTTCATT AGTCCATAAT ATAATCCCAG AAATAAATGC ACAGGCACTC 
CAGTTTTACC CTGCTCTGGA GAGTTTAGAC CTCAGCTCAA ATATAATATC AGAAATCAAG 
ACATCTTCAT TTCCTCGCAT GCAGCTTAAA TACCTGAATT TAAGTAATAA CAGAATAACC 
ACCTTGGAGG CTGGTTGCTT CGATAATTTA TCAAGTTCCT TATTAGTGGT AAAGTTAAAC 
CGTAACCGAA TGAGCATGAT TCCACCTAAG ATCTTCAAGC TGCCTCACCT CCAATTCTTG 
GAACTTAAAA GAAACAGAAT TAAAATTGTG GAAGGTCTTA CATTCCAAGG GCTTGACTCC 
TTAAGATCTT TGAAAATGCA GCGGAATGGA ATTAGCAAAC TTAAGGATGG AGCATTTTTT 
GGCTTGAATA ACATGGAAGA ACTAGAACTG GAACACAACA ACCTTACACG AGTAAACAAG 
GGGTGGTTGT ATGGCTTGCG AATGTTACAG CAGCTCTATG TGAGCCAGAA TGCTATTGAA 
AGAATCAGCC CTGATGCATG GGAGTTCTGC CAAAGACTAT CCGAACTTGA TTTGTCCTAT 
AACCAGCTGA CCCGCCTGGA TGAATCTGCC TTTGTGGGTC TGAGCTTATT GGAGAGATTG 
AATTTAGGAG ACAACAGAGT CACTCATATT GCTGATGGTG TATTTAGATT TCTTTCCAAT 
CTTCAGACAT TAGACTTAAG AAACAATGAA ATTTCATGGG CCATAGAAGA TGCTAGTGAA 
GCCTTTGCTG GACTCACAAG TCTCACTAAA CTAATCTTAC AAGGAAACCA GATTAAGTCA 
ATTACAAAGA AAGCATTCAT TGGTCTTGAA TCCCTTGAGC ATCTAGATTT GAACAATAAT 
GCTATAATGT CTATCCAAGA AAATGCTTTT TCTCAGACTC ATTTAAAAGA ACTGATTCTG 
AACACAAGCA GTTTGCTCTG TGACTGCCAT TTGAAGTGGC TACTTCAATG GTTGGTTGAT 
AATAACTTTC AACATTCTGT GAATGTAAGC TGTGCACACC CTGAATGGCT AGCAGGGCAA 
AGCATCCTGA ATGTGGATCT GAAAGATTTT GTCTGTGAGA TGCCATCTTT TCTGAAAACG 
CCAATGGATC TGACTATTCG CACTGGTGCC ATGGCCAGAT TAGAATGTGC TGCAGAGGGA 
CACCCTGCAC CTCAGATTTC CTGGCAGAAA GATGGTGGTA CTGACTTTCC TGCGGCTCGA 
GAAAGACGCA TGCACGTCAT GCCCGAGGAT GACGTCTTCT TTATTGCCAA TGTGAAAATA 
GAAGATATGG GAATCTATAG CTGCATGGCA CAAAATACAG CAGGAGGTCT CTCAGCAAAT 
GCTTCCCTAA CAGTGTTAGA GACACCCTCA TTTATTAGAC CCCTGGAGGA TAAGACAGTA 
ACACGAGGTG AAACTGCGGT GTTACAGTGC ATAGCTGGAG GGAGTCCTGC CCCTCGTCTC 
AACTGGACTA AAGATGATGG GCCTTTGCTG GTGACAGAAC GACATTTCTT TGCTGCAGCC 
AATCAGCTTC TCATCATTGT AGATGCCGGG CTAGAAGATG CTGGGAAATA TACCTGCATT 
ATGTCTAACA CCCTTGGGAC AGAACGTGGC CACATTTACC TAAATGTCAT TTCATCCCCC 
AATTGTGACT CTTCCCAGAG TAGCATTGGG CATGAAGATG ATGGCTGGAC CACAGTTGGC 
ATTGTCATCA TTGTTGTGGT CTGCTGTGTT GTTGGCACTT CTTTGATCTG GGTCATTGTT 
ATTTACCACA TGAGAAGGAA AAATGAAGAC TATAGTATCA CAAACACAGA GGAGCTCAAT 
CTGCCTGCAG ACATTCCCAG CTACTTGTCT TCCCAAGGAA CGCTGTCTGA GCCACAGGAA 
GGCTACAGCA ACTCTGAGGC AGGCAGTCAT CAGCAACTTA TGCCTCCTGC CAATGGATAT 
ATACACAAAG GCACTGACGG TGGCACTGGT ACCCGGGTGA TTTGCTCAGA TTGTTATGAC 
AATGCCAACA TCTACTCCAG GACCCGAGAA TACTGTCCAT ACACCTATAT TGCTGAGGAG 
GACGTTCTTG ATCAGACACT GTCCAGCCTC ATGGTCCAAA TGCCTAAAGA GACATATTTA 
GTACATCCTC CCCAGGATAC TACTGCCCTA GAGAGCCTGA TACCGTCAGC CAACAGAGAG 
CCATCTGCCT TTCCCACCAA CCATGAGAGG ATAAGTGAGA AGAAACTTCC CTCCACACAG 
ATGAGCGGTG AAACATTGCA GCGGCCCGTG TGGAACATAA ACAGAGAACT AGGCCTGCCT 
CATCCTCCTT TTTCCCAGCA GCCAGTCCAT GAGTCACCAC AACTTCATCA AAATGAGGGC 
CTGGCAGGGA GAGAGCCAGA CTGTTCTGCT TCTTCCATGT CCTGCCACAG GTTACAGGAT 
CATGCTTTTG ATTTTAGTAG GACTCGGAAC ATTCAAGATG GTAGTGAGGG CACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_005271426.1
CDS238..3114
Misc Feature(1)<373..852
Misc Feature(2)532..600
Misc Feature(3)595..774
Misc Feature(4)601..672
Misc Feature(5)673..741
Misc Feature(6)739..990
Misc Feature(7)742..813
Misc Feature(8)817..885
Misc Feature(9)886..957
Misc Feature(10)955..1134
Misc Feature(11)958..1029
Misc Feature(12)1030..1101
Misc Feature(13)1033..1713
Misc Feature(14)1102..1173
Misc Feature(15)1171..1350
Misc Feature(16)1174..1245
Misc Feature(17)1246..1317
Misc Feature(18)1312..1503
Misc Feature(19)1318..1392
Misc Feature(20)1399..1470
Misc Feature(21)1471..1539
Misc Feature(22)1570..1713
Misc Feature(23)1720..1992
Misc Feature(24)1771..1995
Misc Feature(25)2002..2265
Misc Feature(26)2056..2265
Translation

Target ORF information:

RefSeq Version XM_005271369.2
Organism Homo sapiens(human)
Definition Homo sapiens leucine-rich repeats and immunoglobulin like domains 2 (LRIG2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_005271369.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
ATGGCGCCGG CGCCCCTAGG CGTCCCGGAG GAGCAGTTGC TGGGGTGTCG ATCTAGAGTG 
CTTTCTCGGT TACTCTTCAT TGCCCAGACC GCTCTCCTCC TGTTGCCCGC CGCCGGAGCA 
GGTCTCTGCC CCGCGCCCTG CTCCTGCCGC ATTCCTCTCC TGGACTGCAG TCGCAGGAAA 
TTGCCCGCAC CGAGCTGGAG GGCGCTGTCG GGCTTGCTGC CCCCCGACAC CGCTATCCTG 
GATTTCAGTC ATAATCGGTT GTCTAACTGG AACATCAGCT TGGAATCACA AACATTACAG 
GAAGTGAAAA TGAATTACAA TGAACTAACA GAAATCCCGT ATTTTGGAGA ACCTACATCT 
AATATTACTC TACTTTCATT AGTCCATAAT ATAATCCCAG AAATAAATGC ACAGGCACTC 
CAGTTTTACC CTGCTCTGGA GAGTTTAGAC CTCAGCTCAA ATATAATATC AGAAATCAAG 
ACATCTTCAT TTCCTCGCAT GCAGCTTAAA TACCTGAATT TAAGTAATAA CAGAATAACC 
ACCTTGGAGG CTGGTTGCTT CGATAATTTA TCAAGTTCCT TATTAGTGGT AAAGTTAAAC 
CGTAACCGAA TGAGCATGAT TCCACCTAAG ATCTTCAAGC TGCCTCACCT CCAATTCTTG 
GAACTTAAAA GAAACAGAAT TAAAATTGTG GAAGGTCTTA CATTCCAAGG GCTTGACTCC 
TTAAGATCTT TGAAAATGCA GCGGAATGGA ATTAGCAAAC TTAAGGATGG AGCATTTTTT 
GGCTTGAATA ACATGGAAGA ACTAGAACTG GAACACAACA ACCTTACACG AGTAAACAAG 
GGGTGGTTGT ATGGCTTGCG AATGTTACAG CAGCTCTATG TGAGCCAGAA TGCTATTGAA 
AGAATCAGCC CTGATGCATG GGAGTTCTGC CAAAGACTAT CCGAACTTGA TTTGTCCTAT 
AACCAGCTGA CCCGCCTGGA TGAATCTGCC TTTGTGGGTC TGAGCTTATT GGAGAGATTG 
AATTTAGGAG ACAACAGAGT CACTCATATT GCTGATGGTG TATTTAGATT TCTTTCCAAT 
CTTCAGACAT TAGACTTAAG AAACAATGAA ATTTCATGGG CCATAGAAGA TGCTAGTGAA 
GCCTTTGCTG GACTCACAAG TCTCACTAAA CTAATCTTAC AAGGAAACCA GATTAAGTCA 
ATTACAAAGA AAGCATTCAT TGGTCTTGAA TCCCTTGAGC ATCTAGATTT GAACAATAAT 
GCTATAATGT CTATCCAAGA AAATGCTTTT TCTCAGACTC ATTTAAAAGA ACTGATTCTG 
AACACAAGCA GTTTGCTCTG TGACTGCCAT TTGAAGTGGC TACTTCAATG GTTGGTTGAT 
AATAACTTTC AACATTCTGT GAATGTAAGC TGTGCACACC CTGAATGGCT AGCAGGGCAA 
AGCATCCTGA ATGTGGATCT GAAAGATTTT GTCTGTGAGA TGCCATCTTT TCTGAAAACG 
CCAATGGATC TGACTATTCG CACTGGTGCC ATGGCCAGAT TAGAATGTGC TGCAGAGGGA 
CACCCTGCAC CTCAGATTTC CTGGCAGAAA GATGGTGGTA CTGACTTTCC TGCGGCTCGA 
GAAAGACGCA TGCACGTCAT GCCCGAGGAT GACGTCTTCT TTATTGCCAA TGTGAAAATA 
GAAGATATGG GAATCTATAG CTGCATGGCA CAAAATACAG CAGGAGGTCT CTCAGCAAAT 
GCTTCCCTAA CAGTGTTAGA GACACCCTCA TTTATTAGAC CCCTGGAGGA TAAGACAGTA 
ACACGAGGTG AAACTGCGGT GTTACAGTGC ATAGCTGGAG GGAGTCCTGC CCCTCGTCTC 
AACTGGACTA AAGATGATGG GCCTTTGCTG GTGACAGAAC GACATTTCTT TGCTGCAGCC 
AATCAGCTTC TCATCATTGT AGATGCCGGG CTAGAAGATG CTGGGAAATA TACCTGCATT 
ATGTCTAACA CCCTTGGGAC AGAACGTGGC CACATTTACC TAAATGTCAT TTCATCCCCC 
AATTGTGACT CTTCCCAGAG TAGCATTGGG CATGAAGATG ATGGCTGGAC CACAGTTGGC 
ATTGTCATCA TTGTTGTGGT CTGCTGTGTT GTTGGCACTT CTTTGATCTG GGTCATTGTT 
ATTTACCACA TGAGAAGGAA AAATGAAGAC TATAGTATCA CAAACACAGA GGAGCTCAAT 
CTGCCTGCAG ACATTCCCAG CTACTTGTCT TCCCAAGGAA CGCTGTCTGA GCCACAGGAA 
GGCTACAGCA ACTCTGAGGC AGGCAGTCAT CAGCAACTTA TGCCTCCTGC CAATGGATAT 
ATACACAAAG GCACTGACGG TGGCACTGGT ACCCGGGTGA TTTGCTCAGA TTGTTATGAC 
AATGCCAACA TCTACTCCAG GACCCGAGAA TACTGTCCAT ACACCTATAT TGCTGAGGAG 
GACGTTCTTG ATCAGACACT GTCCAGCCTC ATGGTCCAAA TGCCTAAAGA GACATATTTA 
GTACATCCTC CCCAGGATAC TACTGCCCTA GAGAGCCTGA TACCGTCAGC CAACAGAGAG 
CCATCTGCCT TTCCCACCAA CCATGAGAGG ATAAGTGAGA AGAAACTTCC CTCCACACAG 
ATGAGCGGTG AAACATTGCA GCGGCCCGTG TGGAACATAA ACAGAGAACT AGGCCTGCCT 
CATCCTCCTT TTTCCCAGCA GCCAGTCCAT GAGTCACCAC AACTTCATCA AAATGAGGGC 
CTGGCAGGGA GAGAGCCAGA CTGTTCTGCT TCTTCCATGT CCTGCCACAG GTTACAGGAT 
CATGCTTTTG ATTTTAGTAG GACTCGGAAC ATTCAAGATG GTAGTGAGGG CACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu90879
Clone ID Related Accession (Same CDS sequence) XM_017002952.1
Accession Version XM_017002952.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1662bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(human)
Product leucine-rich repeats and immunoglobulin-like domains protein 2 isoform X2
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000001.11) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGAATGTGA CTCTGACGTG CACTGCAGTG AGCAGCAGTG ATTCACCCAT GTCCACTGTG 
TGGCGCAAAG ACAGTGAAAT CCTGTATGAC GTGGATACTG AGAATTTTGT TCGTTATTGG 
CAGCAAGCTG GAGAAGCTCT GGAATATACT AGTATCTTAC ATCTTTTCAA TGTGAATTTC 
ACAGATGAAG GAAAATATCA GTGTATTGTT ACTAATCACT TTGGTTCTAA TTATTCTCAG 
AAAGCCAAAC TGACTGTAAA TGAGATGCCA TCTTTTCTGA AAACGCCAAT GGATCTGACT 
ATTCGCACTG GTGCCATGGC CAGATTAGAA TGTGCTGCAG AGGGACACCC TGCACCTCAG 
ATTTCCTGGC AGAAAGATGG TGGTACTGAC TTTCCTGCGG CTCGAGAAAG ACGCATGCAC 
GTCATGCCCG AGGATGACGT CTTCTTTATT GCCAATGTGA AAATAGAAGA TATGGGAATC 
TATAGCTGCA TGGCACAAAA TACAGCAGGA GGTCTCTCAG CAAATGCTTC CCTAACAGTG 
TTAGAGACAC CCTCATTTAT TAGACCCCTG GAGGATAAGA CAGTAACACG AGGTGAAACT 
GCGGTGTTAC AGTGCATAGC TGGAGGGAGT CCTGCCCCTC GTCTCAACTG GACTAAAGAT 
GATGGGCCTT TGCTGGTGAC AGAACGACAT TTCTTTGCTG CAGCCAATCA GCTTCTCATC 
ATTGTAGATG CCGGGCTAGA AGATGCTGGG AAATATACCT GCATTATGTC TAACACCCTT 
GGGACAGAAC GTGGCCACAT TTACCTAAAT GTCATTTCAT CCCCCAATTG TGACTCTTCC 
CAGAGTAGCA TTGGGCATGA AGATGATGGC TGGACCACAG TTGGCATTGT CATCATTGTT 
GTGGTCTGCT GTGTTGTTGG CACTTCTTTG ATCTGGGTCA TTGTTATTTA CCACATGAGA 
AGGAAAAATG AAGACTATAG TATCACAAAC ACAGAGGAGC TCAATCTGCC TGCAGACATT 
CCCAGCTACT TGTCTTCCCA AGGAACGCTG TCTGAGCCAC AGGAAGGCTA CAGCAACTCT 
GAGGCAGGCA GTCATCAGCA ACTTATGCCT CCTGCCAATG GATATATACA CAAAGGCACT 
GACGGTGGCA CTGGTACCCG GGTGATTTGC TCAGATTGTT ATGACAATGC CAACATCTAC 
TCCAGGACCC GAGAATACTG TCCATACACC TATATTGCTG AGGAGGACGT TCTTGATCAG 
ACACTGTCCA GCCTCATGGT CCAAATGCCT AAAGAGACAT ATTTAGTACA TCCTCCCCAG 
GATACTACTG CCCTAGAGAG CCTGATACCG TCAGCCAACA GAGAGCCATC TGCCTTTCCC 
ACCAACCATG AGAGGATAAG TGAGAAGAAA CTTCCCTCCA CACAGATGAG CGGTGAAACA 
TTGCAGCGGC CCGTGTGGAA CATAAACAGA GAACTAGGCC TGCCTCATCC TCCTTTTTCC 
CAGCAGCCAG TCCATGAGTC ACCACAACTT CATCAAAATG AGGGCCTGGC AGGGAGAGAG 
CCAGACTGTT CTGCTTCTTC CATGTCCTGC CACAGGTTAC AGGATCATGC TTTTGATTTT 
AGTAGGACTC GGAACATTCA AGATGGTAGT GAGGGCACAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_016858441.1
CDS1425..3086
Misc Feature(1)1428..1682
Misc Feature(2)1428..1682
Misc Feature(3)1692..1964
Misc Feature(4)1743..1967
Misc Feature(5)1974..2237
Misc Feature(6)2028..2237
Translation

Target ORF information:

RefSeq Version XM_017002952.1
Organism Homo sapiens(human)
Definition Homo sapiens leucine-rich repeats and immunoglobulin like domains 2 (LRIG2), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_017002952.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
ATGAATGTGA CTCTGACGTG CACTGCAGTG AGCAGCAGTG ATTCACCCAT GTCCACTGTG 
TGGCGCAAAG ACAGTGAAAT CCTGTATGAC GTGGATACTG AGAATTTTGT TCGTTATTGG 
CAGCAAGCTG GAGAAGCTCT GGAATATACT AGTATCTTAC ATCTTTTCAA TGTGAATTTC 
ACAGATGAAG GAAAATATCA GTGTATTGTT ACTAATCACT TTGGTTCTAA TTATTCTCAG 
AAAGCCAAAC TGACTGTAAA TGAGATGCCA TCTTTTCTGA AAACGCCAAT GGATCTGACT 
ATTCGCACTG GTGCCATGGC CAGATTAGAA TGTGCTGCAG AGGGACACCC TGCACCTCAG 
ATTTCCTGGC AGAAAGATGG TGGTACTGAC TTTCCTGCGG CTCGAGAAAG ACGCATGCAC 
GTCATGCCCG AGGATGACGT CTTCTTTATT GCCAATGTGA AAATAGAAGA TATGGGAATC 
TATAGCTGCA TGGCACAAAA TACAGCAGGA GGTCTCTCAG CAAATGCTTC CCTAACAGTG 
TTAGAGACAC CCTCATTTAT TAGACCCCTG GAGGATAAGA CAGTAACACG AGGTGAAACT 
GCGGTGTTAC AGTGCATAGC TGGAGGGAGT CCTGCCCCTC GTCTCAACTG GACTAAAGAT 
GATGGGCCTT TGCTGGTGAC AGAACGACAT TTCTTTGCTG CAGCCAATCA GCTTCTCATC 
ATTGTAGATG CCGGGCTAGA AGATGCTGGG AAATATACCT GCATTATGTC TAACACCCTT 
GGGACAGAAC GTGGCCACAT TTACCTAAAT GTCATTTCAT CCCCCAATTG TGACTCTTCC 
CAGAGTAGCA TTGGGCATGA AGATGATGGC TGGACCACAG TTGGCATTGT CATCATTGTT 
GTGGTCTGCT GTGTTGTTGG CACTTCTTTG ATCTGGGTCA TTGTTATTTA CCACATGAGA 
AGGAAAAATG AAGACTATAG TATCACAAAC ACAGAGGAGC TCAATCTGCC TGCAGACATT 
CCCAGCTACT TGTCTTCCCA AGGAACGCTG TCTGAGCCAC AGGAAGGCTA CAGCAACTCT 
GAGGCAGGCA GTCATCAGCA ACTTATGCCT CCTGCCAATG GATATATACA CAAAGGCACT 
GACGGTGGCA CTGGTACCCG GGTGATTTGC TCAGATTGTT ATGACAATGC CAACATCTAC 
TCCAGGACCC GAGAATACTG TCCATACACC TATATTGCTG AGGAGGACGT TCTTGATCAG 
ACACTGTCCA GCCTCATGGT CCAAATGCCT AAAGAGACAT ATTTAGTACA TCCTCCCCAG 
GATACTACTG CCCTAGAGAG CCTGATACCG TCAGCCAACA GAGAGCCATC TGCCTTTCCC 
ACCAACCATG AGAGGATAAG TGAGAAGAAA CTTCCCTCCA CACAGATGAG CGGTGAAACA 
TTGCAGCGGC CCGTGTGGAA CATAAACAGA GAACTAGGCC TGCCTCATCC TCCTTTTTCC 
CAGCAGCCAG TCCATGAGTC ACCACAACTT CATCAAAATG AGGGCCTGGC AGGGAGAGAG 
CCAGACTGTT CTGCTTCTTC CATGTCCTGC CACAGGTTAC AGGATCATGC TTTTGATTTT 
AGTAGGACTC GGAACATTCA AGATGGTAGT GAGGGCACAT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu63398
Clone ID Related Accession (Same CDS sequence) NM_014813.2
Accession Version NM_014813.2 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 3198bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2017-10-16
Organism Homo sapiens(human)
Product leucine-rich repeats and immunoglobulin-like domains protein 2 isoform 1 precursor
Comment Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DA506094.1, AK291031.1, AL357055.18 and CR936669.1. This sequence is a reference standard in the RefSeqGene project. On Dec 10, 2014 this sequence version replaced NM_014813.1. Transcript Variant: This variant (1) represents the shorter transcript and encodes the longer isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660803.260442.1, SRR1660803.222045.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
ATGGCGCCGG CGCCCCTAGG CGTCCCGGAG GAGCAGTTGC TGGGGTGTCG ATCTAGAGTG 
CTTTCTCGGT TACTCTTCAT TGCCCAGACC GCTCTCCTCC TGTTGCCCGC CGCCGGAGCA 
GGTCTCTGCC CCGCGCCCTG CTCCTGCCGC ATTCCTCTCC TGGACTGCAG TCGCAGGAAA 
TTGCCCGCAC CGAGCTGGAG GGCGCTGTCG GGCTTGCTGC CCCCCGACAC CGCTATCCTG 
GATTTCAGTC ATAATCGGTT GTCTAACTGG AACATCAGCT TGGAATCACA AACATTACAG 
GAAGTGAAAA TGAATTACAA TGAACTAACA GAAATCCCGT ATTTTGGAGA ACCTACATCT 
AATATTACTC TACTTTCATT AGTCCATAAT ATAATCCCAG AAATAAATGC ACAGGCACTC 
CAGTTTTACC CTGCTCTGGA GAGTTTAGAC CTCAGCTCAA ATATAATATC AGAAATCAAG 
ACATCTTCAT TTCCTCGCAT GCAGCTTAAA TACCTGAATT TAAGTAATAA CAGAATAACC 
ACCTTGGAGG CTGGTTGCTT CGATAATTTA TCAAGTTCCT TATTAGTGGT AAAGTTAAAC 
CGTAACCGAA TGAGCATGAT TCCACCTAAG ATCTTCAAGC TGCCTCACCT CCAATTCTTG 
GAACTTAAAA GAAACAGAAT TAAAATTGTG GAAGGTCTTA CATTCCAAGG GCTTGACTCC 
TTAAGATCTT TGAAAATGCA GCGGAATGGA ATTAGCAAAC TTAAGGATGG AGCATTTTTT 
GGCTTGAATA ACATGGAAGA ACTAGAACTG GAACACAACA ACCTTACACG AGTAAACAAG 
GGGTGGTTGT ATGGCTTGCG AATGTTACAG CAGCTCTATG TGAGCCAGAA TGCTATTGAA 
AGAATCAGCC CTGATGCATG GGAGTTCTGC CAAAGACTAT CCGAACTTGA TTTGTCCTAT 
AACCAGCTGA CCCGCCTGGA TGAATCTGCC TTTGTGGGTC TGAGCTTATT GGAGAGATTG 
AATTTAGGAG ACAACAGAGT CACTCATATT GCTGATGGTG TATTTAGATT TCTTTCCAAT 
CTTCAGACAT TAGACTTAAG AAACAATGAA ATTTCATGGG CCATAGAAGA TGCTAGTGAA 
GCCTTTGCTG GACTCACAAG TCTCACTAAA CTAATCTTAC AAGGAAACCA GATTAAGTCA 
ATTACAAAGA AAGCATTCAT TGGTCTTGAA TCCCTTGAGC ATCTAGATTT GAACAATAAT 
GCTATAATGT CTATCCAAGA AAATGCTTTT TCTCAGACTC ATTTAAAAGA ACTGATTCTG 
AACACAAGCA GTTTGCTCTG TGACTGCCAT TTGAAGTGGC TACTTCAATG GTTGGTTGAT 
AATAACTTTC AACATTCTGT GAATGTAAGC TGTGCACACC CTGAATGGCT AGCAGGGCAA 
AGCATCCTGA ATGTGGATCT GAAAGATTTT GTCTGTGATG ATTTTCTCAA GCCACAGATA 
AGGACACATC CTGAAACCAT AATTGCTCTA AGAGGCATGA ATGTGACTCT GACGTGCACT 
GCAGTGAGCA GCAGTGATTC ACCCATGTCC ACTGTGTGGC GCAAAGACAG TGAAATCCTG 
TATGACGTGG ATACTGAGAA TTTTGTTCGT TATTGGCAGC AAGCTGGAGA AGCTCTGGAA 
TATACTAGTA TCTTACATCT TTTCAATGTG AATTTCACAG ATGAAGGAAA ATATCAGTGT 
ATTGTTACTA ATCACTTTGG TTCTAATTAT TCTCAGAAAG CCAAACTGAC TGTAAATGAG 
ATGCCATCTT TTCTGAAAAC GCCAATGGAT CTGACTATTC GCACTGGTGC CATGGCCAGA 
TTAGAATGTG CTGCAGAGGG ACACCCTGCA CCTCAGATTT CCTGGCAGAA AGATGGTGGT 
ACTGACTTTC CTGCGGCTCG AGAAAGACGC ATGCACGTCA TGCCCGAGGA TGACGTCTTC 
TTTATTGCCA ATGTGAAAAT AGAAGATATG GGAATCTATA GCTGCATGGC ACAAAATACA 
GCAGGAGGTC TCTCAGCAAA TGCTTCCCTA ACAGTGTTAG AGACACCCTC ATTTATTAGA 
CCCCTGGAGG ATAAGACAGT AACACGAGGT GAAACTGCGG TGTTACAGTG CATAGCTGGA 
GGGAGTCCTG CCCCTCGTCT CAACTGGACT AAAGATGATG GGCCTTTGCT GGTGACAGAA 
CGACATTTCT TTGCTGCAGC CAATCAGCTT CTCATCATTG TAGATGCCGG GCTAGAAGAT 
GCTGGGAAAT ATACCTGCAT TATGTCTAAC ACCCTTGGGA CAGAACGTGG CCACATTTAC 
CTAAATGTCA TTTCATCCCC CAATTGTGAC TCTTCCCAGA GTAGCATTGG GCATGAAGAT 
GATGGCTGGA CCACAGTTGG CATTGTCATC ATTGTTGTGG TCTGCTGTGT TGTTGGCACT 
TCTTTGATCT GGGTCATTGT TATTTACCAC ATGAGAAGGA AAAATGAAGA CTATAGTATC 
ACAAACACAG AGGAGCTCAA TCTGCCTGCA GACATTCCCA GCTACTTGTC TTCCCAAGGA 
ACGCTGTCTG AGCCACAGGA AGGCTACAGC AACTCTGAGG CAGGCAGTCA TCAGCAACTT 
ATGCCTCCTG CCAATGGATA TATACACAAA GGCACTGACG GTGGCACTGG TACCCGGGTG 
ATTTGCTCAG ATTGTTATGA CAATGCCAAC ATCTACTCCA GGACCCGAGA ATACTGTCCA 
TACACCTATA TTGCTGAGGA GGACGTTCTT GATCAGACAC TGTCCAGCCT CATGGTCCAA 
ATGCCTAAAG AGACATATTT AGTACATCCT CCCCAGGATA CTACTGCCCT AGAGAGCCTG 
ATACCGTCAG CCAACAGAGA GCCATCTGCC TTTCCCACCA ACCATGAGAG GATAAGTGAG 
AAGAAACTTC CCTCCACACA GATGAGCGGT GAAACATTGC AGCGGCCCGT GTGGAACATA 
AACAGAGAAC TAGGCCTGCC TCATCCTCCT TTTTCCCAGC AGCCAGTCCA TGAGTCACCA 
CAACTTCATC AAAATGAGGG CCTGGCAGGG AGAGAGCCAG ACTGTTCTGC TTCTTCCATG 
TCCTGCCACA GGTTACAGGA TCATGCTTTT GATTTTAGTA GGACTCGGAA CATTCAAGAT 
GGTAGTGAGG GCACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_055628.1
CDS238..3435
Misc Feature(1)211..213
Misc Feature(2)<373..852
Misc Feature(3)463..528
Misc Feature(4)529..594
Misc Feature(5)532..600
Misc Feature(6)595..774
Misc Feature(7)598..663
Misc Feature(8)601..672
Misc Feature(9)670..735
Misc Feature(10)673..741
Misc Feature(11)739..990
Misc Feature(12)739..804
Misc Feature(13)742..813
Misc Feature(14)814..879
Misc Feature(15)817..885
Misc Feature(16)883..948
Misc Feature(17)886..957
Misc Feature(18)955..1134
Misc Feature(19)955..1020
Misc Feature(20)958..1029
Misc Feature(21)1027..1092
Misc Feature(22)1030..1101
Misc Feature(23)1033..1713
Misc Feature(24)1099..1164
Misc Feature(25)1102..1173
Misc Feature(26)1171..1350
Misc Feature(27)1171..1236
Misc Feature(28)1174..1245
Misc Feature(29)1243..1308
Misc Feature(30)1246..1317
Misc Feature(31)1312..1503
Misc Feature(32)1315..1383
Misc Feature(33)1318..1392
Misc Feature(34)1396..1461
Misc Feature(35)1399..1470
Misc Feature(36)1468..1533
Misc Feature(37)1471..1539
Misc Feature(38)1570..1716
Misc Feature(39)1741..2031
Misc Feature(40)1747..2031
Misc Feature(41)2041..2313
Misc Feature(42)2092..2316
Misc Feature(43)2323..2586
Misc Feature(44)2377..2586
Misc Feature(45)2659..2721
Misc Feature(46)2953..2955
Exon (1)1..476
Exon (2)477..542
Exon (3)543..617
Exon (4)618..752
Exon (5)753..896
Exon (6)897..1040
Exon (7)1041..1184
Exon (8)1185..1328
Exon (9)1329..1409
Exon (10)1410..1481
Exon (11)1482..1550
Exon (12)1551..1714
Exon (13)1715..2035
Exon (14)2036..2317
Exon (15)2318..2767
Exon (16)2768..2917
Exon (17)2918..3208
Exon (18)3209..4536
Translation

Target ORF information:

RefSeq Version NM_014813.2
Organism Homo sapiens(human)
Definition Homo sapiens leucine rich repeats and immunoglobulin like domains 2 (LRIG2), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_014813.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
ATGGCGCCGG CGCCCCTAGG CGTCCCGGAG GAGCAGTTGC TGGGGTGTCG ATCTAGAGTG 
CTTTCTCGGT TACTCTTCAT TGCCCAGACC GCTCTCCTCC TGTTGCCCGC CGCCGGAGCA 
GGTCTCTGCC CCGCGCCCTG CTCCTGCCGC ATTCCTCTCC TGGACTGCAG TCGCAGGAAA 
TTGCCCGCAC CGAGCTGGAG GGCGCTGTCG GGCTTGCTGC CCCCCGACAC CGCTATCCTG 
GATTTCAGTC ATAATCGGTT GTCTAACTGG AACATCAGCT TGGAATCACA AACATTACAG 
GAAGTGAAAA TGAATTACAA TGAACTAACA GAAATCCCGT ATTTTGGAGA ACCTACATCT 
AATATTACTC TACTTTCATT AGTCCATAAT ATAATCCCAG AAATAAATGC ACAGGCACTC 
CAGTTTTACC CTGCTCTGGA GAGTTTAGAC CTCAGCTCAA ATATAATATC AGAAATCAAG 
ACATCTTCAT TTCCTCGCAT GCAGCTTAAA TACCTGAATT TAAGTAATAA CAGAATAACC 
ACCTTGGAGG CTGGTTGCTT CGATAATTTA TCAAGTTCCT TATTAGTGGT AAAGTTAAAC 
CGTAACCGAA TGAGCATGAT TCCACCTAAG ATCTTCAAGC TGCCTCACCT CCAATTCTTG 
GAACTTAAAA GAAACAGAAT TAAAATTGTG GAAGGTCTTA CATTCCAAGG GCTTGACTCC 
TTAAGATCTT TGAAAATGCA GCGGAATGGA ATTAGCAAAC TTAAGGATGG AGCATTTTTT 
GGCTTGAATA ACATGGAAGA ACTAGAACTG GAACACAACA ACCTTACACG AGTAAACAAG 
GGGTGGTTGT ATGGCTTGCG AATGTTACAG CAGCTCTATG TGAGCCAGAA TGCTATTGAA 
AGAATCAGCC CTGATGCATG GGAGTTCTGC CAAAGACTAT CCGAACTTGA TTTGTCCTAT 
AACCAGCTGA CCCGCCTGGA TGAATCTGCC TTTGTGGGTC TGAGCTTATT GGAGAGATTG 
AATTTAGGAG ACAACAGAGT CACTCATATT GCTGATGGTG TATTTAGATT TCTTTCCAAT 
CTTCAGACAT TAGACTTAAG AAACAATGAA ATTTCATGGG CCATAGAAGA TGCTAGTGAA 
GCCTTTGCTG GACTCACAAG TCTCACTAAA CTAATCTTAC AAGGAAACCA GATTAAGTCA 
ATTACAAAGA AAGCATTCAT TGGTCTTGAA TCCCTTGAGC ATCTAGATTT GAACAATAAT 
GCTATAATGT CTATCCAAGA AAATGCTTTT TCTCAGACTC ATTTAAAAGA ACTGATTCTG 
AACACAAGCA GTTTGCTCTG TGACTGCCAT TTGAAGTGGC TACTTCAATG GTTGGTTGAT 
AATAACTTTC AACATTCTGT GAATGTAAGC TGTGCACACC CTGAATGGCT AGCAGGGCAA 
AGCATCCTGA ATGTGGATCT GAAAGATTTT GTCTGTGATG ATTTTCTCAA GCCACAGATA 
AGGACACATC CTGAAACCAT AATTGCTCTA AGAGGCATGA ATGTGACTCT GACGTGCACT 
GCAGTGAGCA GCAGTGATTC ACCCATGTCC ACTGTGTGGC GCAAAGACAG TGAAATCCTG 
TATGACGTGG ATACTGAGAA TTTTGTTCGT TATTGGCAGC AAGCTGGAGA AGCTCTGGAA 
TATACTAGTA TCTTACATCT TTTCAATGTG AATTTCACAG ATGAAGGAAA ATATCAGTGT 
ATTGTTACTA ATCACTTTGG TTCTAATTAT TCTCAGAAAG CCAAACTGAC TGTAAATGAG 
ATGCCATCTT TTCTGAAAAC GCCAATGGAT CTGACTATTC GCACTGGTGC CATGGCCAGA 
TTAGAATGTG CTGCAGAGGG ACACCCTGCA CCTCAGATTT CCTGGCAGAA AGATGGTGGT 
ACTGACTTTC CTGCGGCTCG AGAAAGACGC ATGCACGTCA TGCCCGAGGA TGACGTCTTC 
TTTATTGCCA ATGTGAAAAT AGAAGATATG GGAATCTATA GCTGCATGGC ACAAAATACA 
GCAGGAGGTC TCTCAGCAAA TGCTTCCCTA ACAGTGTTAG AGACACCCTC ATTTATTAGA 
CCCCTGGAGG ATAAGACAGT AACACGAGGT GAAACTGCGG TGTTACAGTG CATAGCTGGA 
GGGAGTCCTG CCCCTCGTCT CAACTGGACT AAAGATGATG GGCCTTTGCT GGTGACAGAA 
CGACATTTCT TTGCTGCAGC CAATCAGCTT CTCATCATTG TAGATGCCGG GCTAGAAGAT 
GCTGGGAAAT ATACCTGCAT TATGTCTAAC ACCCTTGGGA CAGAACGTGG CCACATTTAC 
CTAAATGTCA TTTCATCCCC CAATTGTGAC TCTTCCCAGA GTAGCATTGG GCATGAAGAT 
GATGGCTGGA CCACAGTTGG CATTGTCATC ATTGTTGTGG TCTGCTGTGT TGTTGGCACT 
TCTTTGATCT GGGTCATTGT TATTTACCAC ATGAGAAGGA AAAATGAAGA CTATAGTATC 
ACAAACACAG AGGAGCTCAA TCTGCCTGCA GACATTCCCA GCTACTTGTC TTCCCAAGGA 
ACGCTGTCTG AGCCACAGGA AGGCTACAGC AACTCTGAGG CAGGCAGTCA TCAGCAACTT 
ATGCCTCCTG CCAATGGATA TATACACAAA GGCACTGACG GTGGCACTGG TACCCGGGTG 
ATTTGCTCAG ATTGTTATGA CAATGCCAAC ATCTACTCCA GGACCCGAGA ATACTGTCCA 
TACACCTATA TTGCTGAGGA GGACGTTCTT GATCAGACAC TGTCCAGCCT CATGGTCCAA 
ATGCCTAAAG AGACATATTT AGTACATCCT CCCCAGGATA CTACTGCCCT AGAGAGCCTG 
ATACCGTCAG CCAACAGAGA GCCATCTGCC TTTCCCACCA ACCATGAGAG GATAAGTGAG 
AAGAAACTTC CCTCCACACA GATGAGCGGT GAAACATTGC AGCGGCCCGT GTGGAACATA 
AACAGAGAAC TAGGCCTGCC TCATCCTCCT TTTTCCCAGC AGCCAGTCCA TGAGTCACCA 
CAACTTCATC AAAATGAGGG CCTGGCAGGG AGAGAGCCAG ACTGTTCTGC TTCTTCCATG 
TCCTGCCACA GGTTACAGGA TCATGCTTTT GATTTTAGTA GGACTCGGAA CATTCAAGAT 
GGTAGTGAGG GCACATGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

LRIGs: A Prognostically Significant Family with Emerging Therapeutic Competence against Cancers.
Current cancer drug targets17(1)3-16(2017)
Malik U,Javed A


book

LRIG and cancer prognosis.
Acta oncologica (Stockholm, Sweden)53(9)1135-42(2014 Sep)
Lindquist D,Kvarnbrink S,Henriksson R,Hedman H


book

LRIG2 expression and prognosis in non-small cell lung cancer.
Oncology letters8(2)667-672(2014 Aug)
Wang G,Wu J,Song H


book

Soluble LRIG2 ectodomain is released from glioblastoma cells and promotes the proliferation and inhibits the apoptosis of glioblastoma cells in vitro and in vivo in a similar manner to the full-length LRIG2.
PloS one9(10)e111419(2014)
Xiao Q,Tan Y,Guo Y,Yang H,Mao F,Xie R,Wang B,Lei T,Guo D