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MAGEC1 cDNA ORF clone, Homo sapiens(Human)

Gene Symbol MAGEC1
Entrez Gene ID 9947
Full Name MAGE family member C1
Synonyms CT7,CT7.1
General protein information
Preferred Names

MAGE family member C1

Names

melanoma-associated antigen C1
MAGE-C1 antigen
cancer/testis antigen 7.1
cancer/testis antigen family 7, member 1
melanoma antigen family C, 1
melanoma antigen family C1

Gene Type protein-coding
Organism Homo sapiens(Human)
Genome

X

Xq27.2

Disorder MIM:

300223


mRNA and Protein(s)

mRNA Protein Name
XM_011531418.2 XP_011529720.1 melanoma-associated antigen C1 isoform X1
NM_005462.4 NP_005453.2 melanoma-associated antigen C1



Homo sapiens (human) MAGEC1 NP_005453.2
Pan troglodytes (chimpanzee) MAGEC1 XP_003317784.1


Related articles in PubMed

The expression of MAGE-C1 and MAGE-C2 in breast cancer and their clinical significance.
Hou S, Sang M, Zhao L, Hou R, Shan B
American journal of surgery211(1)142-51(2016 Jan)

The use of MAGE C1 and flow cytometry to determine the malignant cell type in multiple myeloma.
Wienand K, Shires K
PloS one10(3)e0120734(2015)

Intratumoral Heterogeneity of MAGE-C1/CT7 and MAGE-C2/CT10 Expression in Mucosal Melanoma.
Curioni-Fontecedro A, Pitocco R, Schoenewolf NL, Holzmann D, Soldini D, Dummer R, Calvieri S, Moch H, Mihic-Probst D, Fitsche A
BioMed research international2015432479(2015)

YKL-40 downregulation is a key factor to overcome temozolomide resistance in a glioblastoma cell line.
Akiyama Y, Ashizawa T, Komiyama M, Miyata H, Oshita C, Omiya M, Iizuka A, Kume A, Sugino T, Hayashi N, Mitsuya K, Nakasu Y, Yamaguchi K
Oncology reports32(1)159-66(2014 Jul)

Is there any relationship between gene expression of tumor antigens and CD4+ T cells in multiple myeloma?
Braga WM, da Silva BR, Alves VL, Bortoluzo AB, Atanackovic D, Colleoni GW
Immunotherapy6(5)569-75(2014)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In patients with Colon cancer, the expression of MAGE-C1 gene was related to a favorable prognosis.
Title: [Cancer-testis genes in colon cancer].

MAGE-C1 and MAGE-C2 expressions were positively associated with high tumor grade and reduced recurrence-free survival in breast cancer.
Title: The expression of MAGE-C1 and MAGE-C2 in breast cancer and their clinical significance.

MAGE C1 expression was observed consistently in the early stem cells (CD34+) and early pro-B to pre-B cells (CD34+/-/CD19+), as well as the proliferating plasma cells.
Title: The use of MAGE C1 and flow cytometry to determine the malignant cell type in multiple myeloma.

expression of CT7 and CT10 throughout the different subtypes of mucosal melanoma and tumor development.
Title: Intratumoral Heterogeneity of MAGE-C1/CT7 and MAGE-C2/CT10 Expression in Mucosal Melanoma.

MAGEC1/CT7 was expressed in 66% of MM samples.
Title: Is there any relationship between gene expression of tumor antigens and CD4+ T cells in multiple myeloma?

The following MAGEC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MAGEC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

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***CloneID RefSeq Accession Definition **Vector *Turnaround time Price (USD) Select
OHu23099 NM_005462.4
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Homo sapiens MAGE family member C1 (MAGEC1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $559.30
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OHu23099 XM_011531418.2
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Homo sapiens MAGE family member C1 (MAGEC1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector TBD $559.30
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.


CloneID OHu23099
Clone ID Related Accession (Same CDS sequence) XM_011531418.2 , NM_005462.4
Accession Version NM_005462.4 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3429bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-10-07
Organism Homo sapiens(Human)
Product melanoma-associated antigen C1
Comment REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DB065460.1, AF056334.1, AL022152.1 and BQ772869.1. This sequence is a reference standard in the RefSeqGene project. On Oct 23, 2009 this sequence version replaced NM_005462.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AF056334.1, DB099371.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968968, SAMEA2148093 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
ATGGGGGACA AGGATATGCC TACTGCTGGG ATGCCGAGTC TTCTCCAGAG TTCCTCTGAG 
AGTCCTCAGA GTTGTCCTGA GGGGGAGGAC TCCCAGTCTC CTCTCCAGAT TCCCCAGAGT
TCTCCTGAGA GCGACGACAC CCTGTATCCT CTCCAGAGTC CTCAGAGTCG TTCTGAGGGG
GAGGACTCCT CGGATCCTCT CCAGAGACCT CCTGAGGGGA AGGACTCCCA GTCTCCTCTC
CAGATTCCCC AGAGTTCTCC TGAGGGCGAC GACACCCAGT CTCCTCTCCA GAATTCTCAG
AGTTCTCCTG AGGGGAAGGA CTCCCTGTCT CCTCTAGAGA TTTCTCAGAG CCCTCCTGAG
GGTGAGGATG TCCAGTCTCC TCTGCAGAAT CCTGCGAGTT CCTTCTTCTC CTCTGCTTTA
TTGAGTATTT TCCAGAGTTC CCCTGAGAGT ACTCAAAGTC CTTTTGAGGG TTTTCCCCAG
TCTGTTCTCC AGATTCCTGT GAGCGCCGCC TCCTCCTCCA CTTTAGTGAG TATTTTCCAG
AGTTCCCCTG AGAGTACTCA AAGTCCTTTT GAGGGTTTTC CCCAGTCTCC ACTCCAGATT
CCTGTGAGCC GCTCCTTCTC CTCCACTTTA TTGAGTATTT TCCAGAGTTC CCCTGAGAGA
ACTCAGAGTA CTTTTGAGGG TTTTGCCCAG TCTCCTCTCC AGATTCCTGT GAGCCCCTCC
TCCTCCTCCA CTTTACTGAG TCTTTTCCAG AGTTTCTCTG AGAGAACTCA GAGTACTTTT
GAGGGTTTTG CCCAGTCTTC TCTCCAGATT CCTGTGAGCC CCTCCTTCTC CTCCACTTTA
GTGAGTCTTT TCCAGAGTTC CCCTGAGAGA ACTCAGAGTA CTTTTGAGGG TTTTCCCCAG
TCTCCTCTCC AGATTCCTGT GAGCTCCTCC TCCTCCTCCA CTTTATTGAG TCTTTTCCAG
AGTTCCCCTG AGAGAACTCA CAGTACTTTT GAGGGTTTTC CCCAGTCTCT TCTCCAGATT
CCTATGACCT CCTCCTTCTC CTCTACTTTA TTGAGTATTT TCCAGAGTTC TCCTGAGAGT
GCTCAAAGTA CTTTTGAGGG TTTTCCCCAG TCTCCTCTCC AGATTCCTGG GAGCCCCTCC
TTCTCCTCCA CTTTACTGAG TCTTTTCCAG AGTTCCCCTG AGAGAACTCA CAGTACTTTT
GAGGGTTTTC CCCAGTCTCC TCTCCAGATT CCTATGACCT CCTCCTTCTC CTCTACTTTA
TTGAGTATTT TACAGAGTTC TCCTGAGAGT GCTCAAAGTG CTTTTGAGGG TTTTCCCCAG
TCTCCTCTCC AGATTCCTGT GAGCTCCTCT TTCTCCTACA CTTTATTGAG TCTTTTCCAG
AGTTCCCCTG AGAGAACTCA CAGTACTTTT GAGGGTTTTC CCCAGTCTCC TCTCCAGATT
CCTGTGAGCT CCTCCTCCTC CTCCTCCACT TTATTGAGTC TTTTCCAGAG TTCCCCTGAG
TGTACTCAAA GTACTTTTGA GGGTTTTCCC CAGTCTCCTC TCCAGATTCC TCAGAGTCCT
CCTGAAGGGG AGAATACCCA TTCTCCTCTC CAGATTGTTC CAAGTCTTCC TGAGTGGGAG
GACTCCCTGT CTCCTCACTA CTTTCCTCAG AGCCCTCCTC AGGGGGAGGA CTCCCTATCT
CCTCACTACT TTCCTCAGAG CCCTCCTCAG GGGGAGGACT CCCTGTCTCC TCACTACTTT
CCTCAGAGCC CTCAGGGGGA GGACTCCCTG TCTCCTCACT ACTTTCCTCA GAGCCCTCCT
CAGGGGGAGG ACTCCATGTC TCCTCTCTAC TTTCCTCAGA GTCCTCTTCA GGGGGAGGAA
TTCCAGTCTT CTCTCCAGAG CCCTGTGAGC ATCTGCTCCT CCTCCACTCC ATCCAGTCTT
CCCCAGAGTT TCCCTGAGAG TTCTCAGAGT CCTCCTGAGG GGCCTGTCCA GTCTCCTCTC
CATAGTCCTC AGAGCCCTCC TGAGGGGATG CACTCCCAAT CTCCTCTCCA GAGTCCTGAG
AGTGCTCCTG AGGGGGAGGA TTCCCTGTCT CCTCTCCAAA TTCCTCAGAG TCCTCTTGAG
GGAGAGGACT CCCTGTCTTC TCTCCATTTT CCTCAGAGTC CTCCTGAGTG GGAGGACTCC
CTCTCTCCTC TCCACTTTCC TCAGTTTCCT CCTCAGGGGG AGGACTTCCA GTCTTCTCTC
CAGAGTCCTG TGAGTATCTG CTCCTCCTCC ACTTCTTTGA GTCTTCCCCA GAGTTTCCCT
GAGAGTCCTC AGAGTCCTCC TGAGGGGCCT GCTCAGTCTC CTCTCCAGAG ACCTGTCAGC
TCCTTCTTCT CCTACACTTT AGCGAGTCTT CTCCAAAGTT CCCATGAGAG TCCTCAGAGT
CCTCCTGAGG GGCCTGCCCA GTCTCCTCTC CAGAGTCCTG TGAGCTCCTT CCCCTCCTCC
ACTTCATCGA GTCTTTCCCA GAGTTCTCCT GTGAGCTCCT TCCCCTCCTC CACTTCATCG
AGTCTTTCCA AGAGTTCCCC TGAGAGTCCT CTCCAGAGTC CTGTGATCTC CTTCTCCTCC
TCCACTTCAT TGAGCCCATT CAGTGAAGAG TCCAGCAGCC CAGTAGATGA ATATACAAGT
TCCTCAGACA CCTTGCTAGA GAGTGATTCC TTGACAGACA GCGAGTCCTT GATAGAGAGC
GAGCCCTTGT TCACTTATAC ACTGGATGAA AAGGTGGACG AGTTGGCGCG GTTTCTTCTC
CTCAAATATC AAGTGAAGCA GCCTATCACA AAGGCAGAGA TGCTGACGAA TGTCATCAGC
AGGTACACGG GCTACTTTCC TGTGATCTTC AGGAAAGCCC GTGAGTTCAT AGAGATACTT
TTTGGCATTT CCCTGAGAGA AGTGGACCCT GATGACTCCT ATGTCTTTGT AAACACATTA
GACCTCACCT CTGAGGGGTG TCTGAGTGAT GAGCAGGGCA TGTCCCAGAA CCGCCTCCTG
ATTCTTATTC TGAGTATCAT CTTCATAAAG GGCACCTATG CCTCTGAGGA GGTCATCTGG
GATGTGCTGA GTGGAATAGG GGTGCGTGCT GGGAGGGAGC ACTTTGCCTT TGGGGAGCCC
AGGGAGCTCC TCACTAAAGT TTGGGTGCAG GAACATTACC TAGAGTACCG GGAGGTGCCC
AACTCTTCTC CTCCTCGTTA CGAATTCCTG TGGGGTCCAA GAGCTCATTC AGAAGTCATT
AAGAGGAAAG TAGTAGAGTT TTTGGCCATG CTAAAGAATA CCGTCCCTAT TACCTTTCCA
TCCTCTTACA AGGATGCTTT GAAAGATGTG GAAGAGAGAG CCCAGGCCAT AATTGACACC
ACAGATGATT CGACTGCCAC AGAAAGTGCA AGCTCCAGTG TCATGTCCCC CAGCTTCTCT
TCTGAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_005453.2
CDS325..3753
Misc Feature(1)283..285
Misc Feature(2)511..513
Misc Feature(3)943..945
Misc Feature(4)1468..1470
Misc Feature(5)3067..3570
Misc Feature(6)3511..3513
Exon (1)1..123
Exon (2)124..221
Exon (3)222..328
Exon (4)329..4321
Translation

Target ORF information:

RefSeq Version NM_005462.4
Organism Homo sapiens(Human)
Definition Homo sapiens MAGE family member C1 (MAGEC1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
NM_005462.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
ATGGGGGACA AGGATATGCC TACTGCTGGG ATGCCGAGTC TTCTCCAGAG TTCCTCTGAG 
AGTCCTCAGA GTTGTCCTGA GGGGGAGGAC TCCCAGTCTC CTCTCCAGAT TCCCCAGAGT
TCTCCTGAGA GCGACGACAC CCTGTATCCT CTCCAGAGTC CTCAGAGTCG TTCTGAGGGG
GAGGACTCCT CGGATCCTCT CCAGAGACCT CCTGAGGGGA AGGACTCCCA GTCTCCTCTC
CAGATTCCCC AGAGTTCTCC TGAGGGCGAC GACACCCAGT CTCCTCTCCA GAATTCTCAG
AGTTCTCCTG AGGGGAAGGA CTCCCTGTCT CCTCTAGAGA TTTCTCAGAG CCCTCCTGAG
GGTGAGGATG TCCAGTCTCC TCTGCAGAAT CCTGCGAGTT CCTTCTTCTC CTCTGCTTTA
TTGAGTATTT TCCAGAGTTC CCCTGAGAGT ACTCAAAGTC CTTTTGAGGG TTTTCCCCAG
TCTGTTCTCC AGATTCCTGT GAGCGCCGCC TCCTCCTCCA CTTTAGTGAG TATTTTCCAG
AGTTCCCCTG AGAGTACTCA AAGTCCTTTT GAGGGTTTTC CCCAGTCTCC ACTCCAGATT
CCTGTGAGCC GCTCCTTCTC CTCCACTTTA TTGAGTATTT TCCAGAGTTC CCCTGAGAGA
ACTCAGAGTA CTTTTGAGGG TTTTGCCCAG TCTCCTCTCC AGATTCCTGT GAGCCCCTCC
TCCTCCTCCA CTTTACTGAG TCTTTTCCAG AGTTTCTCTG AGAGAACTCA GAGTACTTTT
GAGGGTTTTG CCCAGTCTTC TCTCCAGATT CCTGTGAGCC CCTCCTTCTC CTCCACTTTA
GTGAGTCTTT TCCAGAGTTC CCCTGAGAGA ACTCAGAGTA CTTTTGAGGG TTTTCCCCAG
TCTCCTCTCC AGATTCCTGT GAGCTCCTCC TCCTCCTCCA CTTTATTGAG TCTTTTCCAG
AGTTCCCCTG AGAGAACTCA CAGTACTTTT GAGGGTTTTC CCCAGTCTCT TCTCCAGATT
CCTATGACCT CCTCCTTCTC CTCTACTTTA TTGAGTATTT TCCAGAGTTC TCCTGAGAGT
GCTCAAAGTA CTTTTGAGGG TTTTCCCCAG TCTCCTCTCC AGATTCCTGG GAGCCCCTCC
TTCTCCTCCA CTTTACTGAG TCTTTTCCAG AGTTCCCCTG AGAGAACTCA CAGTACTTTT
GAGGGTTTTC CCCAGTCTCC TCTCCAGATT CCTATGACCT CCTCCTTCTC CTCTACTTTA
TTGAGTATTT TACAGAGTTC TCCTGAGAGT GCTCAAAGTG CTTTTGAGGG TTTTCCCCAG
TCTCCTCTCC AGATTCCTGT GAGCTCCTCT TTCTCCTACA CTTTATTGAG TCTTTTCCAG
AGTTCCCCTG AGAGAACTCA CAGTACTTTT GAGGGTTTTC CCCAGTCTCC TCTCCAGATT
CCTGTGAGCT CCTCCTCCTC CTCCTCCACT TTATTGAGTC TTTTCCAGAG TTCCCCTGAG
TGTACTCAAA GTACTTTTGA GGGTTTTCCC CAGTCTCCTC TCCAGATTCC TCAGAGTCCT
CCTGAAGGGG AGAATACCCA TTCTCCTCTC CAGATTGTTC CAAGTCTTCC TGAGTGGGAG
GACTCCCTGT CTCCTCACTA CTTTCCTCAG AGCCCTCCTC AGGGGGAGGA CTCCCTATCT
CCTCACTACT TTCCTCAGAG CCCTCCTCAG GGGGAGGACT CCCTGTCTCC TCACTACTTT
CCTCAGAGCC CTCAGGGGGA GGACTCCCTG TCTCCTCACT ACTTTCCTCA GAGCCCTCCT
CAGGGGGAGG ACTCCATGTC TCCTCTCTAC TTTCCTCAGA GTCCTCTTCA GGGGGAGGAA
TTCCAGTCTT CTCTCCAGAG CCCTGTGAGC ATCTGCTCCT CCTCCACTCC ATCCAGTCTT
CCCCAGAGTT TCCCTGAGAG TTCTCAGAGT CCTCCTGAGG GGCCTGTCCA GTCTCCTCTC
CATAGTCCTC AGAGCCCTCC TGAGGGGATG CACTCCCAAT CTCCTCTCCA GAGTCCTGAG
AGTGCTCCTG AGGGGGAGGA TTCCCTGTCT CCTCTCCAAA TTCCTCAGAG TCCTCTTGAG
GGAGAGGACT CCCTGTCTTC TCTCCATTTT CCTCAGAGTC CTCCTGAGTG GGAGGACTCC
CTCTCTCCTC TCCACTTTCC TCAGTTTCCT CCTCAGGGGG AGGACTTCCA GTCTTCTCTC
CAGAGTCCTG TGAGTATCTG CTCCTCCTCC ACTTCTTTGA GTCTTCCCCA GAGTTTCCCT
GAGAGTCCTC AGAGTCCTCC TGAGGGGCCT GCTCAGTCTC CTCTCCAGAG ACCTGTCAGC
TCCTTCTTCT CCTACACTTT AGCGAGTCTT CTCCAAAGTT CCCATGAGAG TCCTCAGAGT
CCTCCTGAGG GGCCTGCCCA GTCTCCTCTC CAGAGTCCTG TGAGCTCCTT CCCCTCCTCC
ACTTCATCGA GTCTTTCCCA GAGTTCTCCT GTGAGCTCCT TCCCCTCCTC CACTTCATCG
AGTCTTTCCA AGAGTTCCCC TGAGAGTCCT CTCCAGAGTC CTGTGATCTC CTTCTCCTCC
TCCACTTCAT TGAGCCCATT CAGTGAAGAG TCCAGCAGCC CAGTAGATGA ATATACAAGT
TCCTCAGACA CCTTGCTAGA GAGTGATTCC TTGACAGACA GCGAGTCCTT GATAGAGAGC
GAGCCCTTGT TCACTTATAC ACTGGATGAA AAGGTGGACG AGTTGGCGCG GTTTCTTCTC
CTCAAATATC AAGTGAAGCA GCCTATCACA AAGGCAGAGA TGCTGACGAA TGTCATCAGC
AGGTACACGG GCTACTTTCC TGTGATCTTC AGGAAAGCCC GTGAGTTCAT AGAGATACTT
TTTGGCATTT CCCTGAGAGA AGTGGACCCT GATGACTCCT ATGTCTTTGT AAACACATTA
GACCTCACCT CTGAGGGGTG TCTGAGTGAT GAGCAGGGCA TGTCCCAGAA CCGCCTCCTG
ATTCTTATTC TGAGTATCAT CTTCATAAAG GGCACCTATG CCTCTGAGGA GGTCATCTGG
GATGTGCTGA GTGGAATAGG GGTGCGTGCT GGGAGGGAGC ACTTTGCCTT TGGGGAGCCC
AGGGAGCTCC TCACTAAAGT TTGGGTGCAG GAACATTACC TAGAGTACCG GGAGGTGCCC
AACTCTTCTC CTCCTCGTTA CGAATTCCTG TGGGGTCCAA GAGCTCATTC AGAAGTCATT
AAGAGGAAAG TAGTAGAGTT TTTGGCCATG CTAAAGAATA CCGTCCCTAT TACCTTTCCA
TCCTCTTACA AGGATGCTTT GAAAGATGTG GAAGAGAGAG CCCAGGCCAT AATTGACACC
ACAGATGATT CGACTGCCAC AGAAAGTGCA AGCTCCAGTG TCATGTCCCC CAGCTTCTCT
TCTGAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OHu23099
Clone ID Related Accession (Same CDS sequence) XM_011531418.2 , NM_005462.4
Accession Version XM_011531418.2 Latest version! Documents for ORF clone product in dufault vector
Sequence Information ORF Nucleotide Sequence (Length: 3429bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ® Seamless cloning technology
Insert Structure linear
Update Date 2016-06-06
Organism Homo sapiens(Human)
Product melanoma-associated antigen C1 isoform X1
Comment MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000023.11) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 6, 2016 this sequence version replaced XM_011531418.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
ATGGGGGACA AGGATATGCC TACTGCTGGG ATGCCGAGTC TTCTCCAGAG TTCCTCTGAG 
AGTCCTCAGA GTTGTCCTGA GGGGGAGGAC TCCCAGTCTC CTCTCCAGAT TCCCCAGAGT
TCTCCTGAGA GCGACGACAC CCTGTATCCT CTCCAGAGTC CTCAGAGTCG TTCTGAGGGG
GAGGACTCCT CGGATCCTCT CCAGAGACCT CCTGAGGGGA AGGACTCCCA GTCTCCTCTC
CAGATTCCCC AGAGTTCTCC TGAGGGCGAC GACACCCAGT CTCCTCTCCA GAATTCTCAG
AGTTCTCCTG AGGGGAAGGA CTCCCTGTCT CCTCTAGAGA TTTCTCAGAG CCCTCCTGAG
GGTGAGGATG TCCAGTCTCC TCTGCAGAAT CCTGCGAGTT CCTTCTTCTC CTCTGCTTTA
TTGAGTATTT TCCAGAGTTC CCCTGAGAGT ACTCAAAGTC CTTTTGAGGG TTTTCCCCAG
TCTGTTCTCC AGATTCCTGT GAGCGCCGCC TCCTCCTCCA CTTTAGTGAG TATTTTCCAG
AGTTCCCCTG AGAGTACTCA AAGTCCTTTT GAGGGTTTTC CCCAGTCTCC ACTCCAGATT
CCTGTGAGCC GCTCCTTCTC CTCCACTTTA TTGAGTATTT TCCAGAGTTC CCCTGAGAGA
ACTCAGAGTA CTTTTGAGGG TTTTGCCCAG TCTCCTCTCC AGATTCCTGT GAGCCCCTCC
TCCTCCTCCA CTTTACTGAG TCTTTTCCAG AGTTTCTCTG AGAGAACTCA GAGTACTTTT
GAGGGTTTTG CCCAGTCTTC TCTCCAGATT CCTGTGAGCC CCTCCTTCTC CTCCACTTTA
GTGAGTCTTT TCCAGAGTTC CCCTGAGAGA ACTCAGAGTA CTTTTGAGGG TTTTCCCCAG
TCTCCTCTCC AGATTCCTGT GAGCTCCTCC TCCTCCTCCA CTTTATTGAG TCTTTTCCAG
AGTTCCCCTG AGAGAACTCA CAGTACTTTT GAGGGTTTTC CCCAGTCTCT TCTCCAGATT
CCTATGACCT CCTCCTTCTC CTCTACTTTA TTGAGTATTT TCCAGAGTTC TCCTGAGAGT
GCTCAAAGTA CTTTTGAGGG TTTTCCCCAG TCTCCTCTCC AGATTCCTGG GAGCCCCTCC
TTCTCCTCCA CTTTACTGAG TCTTTTCCAG AGTTCCCCTG AGAGAACTCA CAGTACTTTT
GAGGGTTTTC CCCAGTCTCC TCTCCAGATT CCTATGACCT CCTCCTTCTC CTCTACTTTA
TTGAGTATTT TACAGAGTTC TCCTGAGAGT GCTCAAAGTG CTTTTGAGGG TTTTCCCCAG
TCTCCTCTCC AGATTCCTGT GAGCTCCTCT TTCTCCTACA CTTTATTGAG TCTTTTCCAG
AGTTCCCCTG AGAGAACTCA CAGTACTTTT GAGGGTTTTC CCCAGTCTCC TCTCCAGATT
CCTGTGAGCT CCTCCTCCTC CTCCTCCACT TTATTGAGTC TTTTCCAGAG TTCCCCTGAG
TGTACTCAAA GTACTTTTGA GGGTTTTCCC CAGTCTCCTC TCCAGATTCC TCAGAGTCCT
CCTGAAGGGG AGAATACCCA TTCTCCTCTC CAGATTGTTC CAAGTCTTCC TGAGTGGGAG
GACTCCCTGT CTCCTCACTA CTTTCCTCAG AGCCCTCCTC AGGGGGAGGA CTCCCTATCT
CCTCACTACT TTCCTCAGAG CCCTCCTCAG GGGGAGGACT CCCTGTCTCC TCACTACTTT
CCTCAGAGCC CTCAGGGGGA GGACTCCCTG TCTCCTCACT ACTTTCCTCA GAGCCCTCCT
CAGGGGGAGG ACTCCATGTC TCCTCTCTAC TTTCCTCAGA GTCCTCTTCA GGGGGAGGAA
TTCCAGTCTT CTCTCCAGAG CCCTGTGAGC ATCTGCTCCT CCTCCACTCC ATCCAGTCTT
CCCCAGAGTT TCCCTGAGAG TTCTCAGAGT CCTCCTGAGG GGCCTGTCCA GTCTCCTCTC
CATAGTCCTC AGAGCCCTCC TGAGGGGATG CACTCCCAAT CTCCTCTCCA GAGTCCTGAG
AGTGCTCCTG AGGGGGAGGA TTCCCTGTCT CCTCTCCAAA TTCCTCAGAG TCCTCTTGAG
GGAGAGGACT CCCTGTCTTC TCTCCATTTT CCTCAGAGTC CTCCTGAGTG GGAGGACTCC
CTCTCTCCTC TCCACTTTCC TCAGTTTCCT CCTCAGGGGG AGGACTTCCA GTCTTCTCTC
CAGAGTCCTG TGAGTATCTG CTCCTCCTCC ACTTCTTTGA GTCTTCCCCA GAGTTTCCCT
GAGAGTCCTC AGAGTCCTCC TGAGGGGCCT GCTCAGTCTC CTCTCCAGAG ACCTGTCAGC
TCCTTCTTCT CCTACACTTT AGCGAGTCTT CTCCAAAGTT CCCATGAGAG TCCTCAGAGT
CCTCCTGAGG GGCCTGCCCA GTCTCCTCTC CAGAGTCCTG TGAGCTCCTT CCCCTCCTCC
ACTTCATCGA GTCTTTCCCA GAGTTCTCCT GTGAGCTCCT TCCCCTCCTC CACTTCATCG
AGTCTTTCCA AGAGTTCCCC TGAGAGTCCT CTCCAGAGTC CTGTGATCTC CTTCTCCTCC
TCCACTTCAT TGAGCCCATT CAGTGAAGAG TCCAGCAGCC CAGTAGATGA ATATACAAGT
TCCTCAGACA CCTTGCTAGA GAGTGATTCC TTGACAGACA GCGAGTCCTT GATAGAGAGC
GAGCCCTTGT TCACTTATAC ACTGGATGAA AAGGTGGACG AGTTGGCGCG GTTTCTTCTC
CTCAAATATC AAGTGAAGCA GCCTATCACA AAGGCAGAGA TGCTGACGAA TGTCATCAGC
AGGTACACGG GCTACTTTCC TGTGATCTTC AGGAAAGCCC GTGAGTTCAT AGAGATACTT
TTTGGCATTT CCCTGAGAGA AGTGGACCCT GATGACTCCT ATGTCTTTGT AAACACATTA
GACCTCACCT CTGAGGGGTG TCTGAGTGAT GAGCAGGGCA TGTCCCAGAA CCGCCTCCTG
ATTCTTATTC TGAGTATCAT CTTCATAAAG GGCACCTATG CCTCTGAGGA GGTCATCTGG
GATGTGCTGA GTGGAATAGG GGTGCGTGCT GGGAGGGAGC ACTTTGCCTT TGGGGAGCCC
AGGGAGCTCC TCACTAAAGT TTGGGTGCAG GAACATTACC TAGAGTACCG GGAGGTGCCC
AACTCTTCTC CTCCTCGTTA CGAATTCCTG TGGGGTCCAA GAGCTCATTC AGAAGTCATT
AAGAGGAAAG TAGTAGAGTT TTTGGCCATG CTAAAGAATA CCGTCCCTAT TACCTTTCCA
TCCTCTTACA AGGATGCTTT GAAAGATGTG GAAGAGAGAG CCCAGGCCAT AATTGACACC
ACAGATGATT CGACTGCCAC AGAAAGTGCA AGCTCCAGTG TCATGTCCCC CAGCTTCTCT
TCTGAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011529720.1
CDS261..3689
Misc Feature(1)3003..3506
Translation

Target ORF information:

RefSeq Version XM_011531418.2
Organism Homo sapiens(Human)
Definition Homo sapiens MAGE family member C1 (MAGEC1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
XM_011531418.2

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
1441
1501
1561
1621
1681
1741
1801
1861
1921
1981
2041
2101
2161
2221
2281
2341
2401
2461
2521
2581
2641
2701
2761
2821
2881
2941
3001
3061
3121
3181
3241
3301
3361
3421
ATGGGGGACA AGGATATGCC TACTGCTGGG ATGCCGAGTC TTCTCCAGAG TTCCTCTGAG 
AGTCCTCAGA GTTGTCCTGA GGGGGAGGAC TCCCAGTCTC CTCTCCAGAT TCCCCAGAGT
TCTCCTGAGA GCGACGACAC CCTGTATCCT CTCCAGAGTC CTCAGAGTCG TTCTGAGGGG
GAGGACTCCT CGGATCCTCT CCAGAGACCT CCTGAGGGGA AGGACTCCCA GTCTCCTCTC
CAGATTCCCC AGAGTTCTCC TGAGGGCGAC GACACCCAGT CTCCTCTCCA GAATTCTCAG
AGTTCTCCTG AGGGGAAGGA CTCCCTGTCT CCTCTAGAGA TTTCTCAGAG CCCTCCTGAG
GGTGAGGATG TCCAGTCTCC TCTGCAGAAT CCTGCGAGTT CCTTCTTCTC CTCTGCTTTA
TTGAGTATTT TCCAGAGTTC CCCTGAGAGT ACTCAAAGTC CTTTTGAGGG TTTTCCCCAG
TCTGTTCTCC AGATTCCTGT GAGCGCCGCC TCCTCCTCCA CTTTAGTGAG TATTTTCCAG
AGTTCCCCTG AGAGTACTCA AAGTCCTTTT GAGGGTTTTC CCCAGTCTCC ACTCCAGATT
CCTGTGAGCC GCTCCTTCTC CTCCACTTTA TTGAGTATTT TCCAGAGTTC CCCTGAGAGA
ACTCAGAGTA CTTTTGAGGG TTTTGCCCAG TCTCCTCTCC AGATTCCTGT GAGCCCCTCC
TCCTCCTCCA CTTTACTGAG TCTTTTCCAG AGTTTCTCTG AGAGAACTCA GAGTACTTTT
GAGGGTTTTG CCCAGTCTTC TCTCCAGATT CCTGTGAGCC CCTCCTTCTC CTCCACTTTA
GTGAGTCTTT TCCAGAGTTC CCCTGAGAGA ACTCAGAGTA CTTTTGAGGG TTTTCCCCAG
TCTCCTCTCC AGATTCCTGT GAGCTCCTCC TCCTCCTCCA CTTTATTGAG TCTTTTCCAG
AGTTCCCCTG AGAGAACTCA CAGTACTTTT GAGGGTTTTC CCCAGTCTCT TCTCCAGATT
CCTATGACCT CCTCCTTCTC CTCTACTTTA TTGAGTATTT TCCAGAGTTC TCCTGAGAGT
GCTCAAAGTA CTTTTGAGGG TTTTCCCCAG TCTCCTCTCC AGATTCCTGG GAGCCCCTCC
TTCTCCTCCA CTTTACTGAG TCTTTTCCAG AGTTCCCCTG AGAGAACTCA CAGTACTTTT
GAGGGTTTTC CCCAGTCTCC TCTCCAGATT CCTATGACCT CCTCCTTCTC CTCTACTTTA
TTGAGTATTT TACAGAGTTC TCCTGAGAGT GCTCAAAGTG CTTTTGAGGG TTTTCCCCAG
TCTCCTCTCC AGATTCCTGT GAGCTCCTCT TTCTCCTACA CTTTATTGAG TCTTTTCCAG
AGTTCCCCTG AGAGAACTCA CAGTACTTTT GAGGGTTTTC CCCAGTCTCC TCTCCAGATT
CCTGTGAGCT CCTCCTCCTC CTCCTCCACT TTATTGAGTC TTTTCCAGAG TTCCCCTGAG
TGTACTCAAA GTACTTTTGA GGGTTTTCCC CAGTCTCCTC TCCAGATTCC TCAGAGTCCT
CCTGAAGGGG AGAATACCCA TTCTCCTCTC CAGATTGTTC CAAGTCTTCC TGAGTGGGAG
GACTCCCTGT CTCCTCACTA CTTTCCTCAG AGCCCTCCTC AGGGGGAGGA CTCCCTATCT
CCTCACTACT TTCCTCAGAG CCCTCCTCAG GGGGAGGACT CCCTGTCTCC TCACTACTTT
CCTCAGAGCC CTCAGGGGGA GGACTCCCTG TCTCCTCACT ACTTTCCTCA GAGCCCTCCT
CAGGGGGAGG ACTCCATGTC TCCTCTCTAC TTTCCTCAGA GTCCTCTTCA GGGGGAGGAA
TTCCAGTCTT CTCTCCAGAG CCCTGTGAGC ATCTGCTCCT CCTCCACTCC ATCCAGTCTT
CCCCAGAGTT TCCCTGAGAG TTCTCAGAGT CCTCCTGAGG GGCCTGTCCA GTCTCCTCTC
CATAGTCCTC AGAGCCCTCC TGAGGGGATG CACTCCCAAT CTCCTCTCCA GAGTCCTGAG
AGTGCTCCTG AGGGGGAGGA TTCCCTGTCT CCTCTCCAAA TTCCTCAGAG TCCTCTTGAG
GGAGAGGACT CCCTGTCTTC TCTCCATTTT CCTCAGAGTC CTCCTGAGTG GGAGGACTCC
CTCTCTCCTC TCCACTTTCC TCAGTTTCCT CCTCAGGGGG AGGACTTCCA GTCTTCTCTC
CAGAGTCCTG TGAGTATCTG CTCCTCCTCC ACTTCTTTGA GTCTTCCCCA GAGTTTCCCT
GAGAGTCCTC AGAGTCCTCC TGAGGGGCCT GCTCAGTCTC CTCTCCAGAG ACCTGTCAGC
TCCTTCTTCT CCTACACTTT AGCGAGTCTT CTCCAAAGTT CCCATGAGAG TCCTCAGAGT
CCTCCTGAGG GGCCTGCCCA GTCTCCTCTC CAGAGTCCTG TGAGCTCCTT CCCCTCCTCC
ACTTCATCGA GTCTTTCCCA GAGTTCTCCT GTGAGCTCCT TCCCCTCCTC CACTTCATCG
AGTCTTTCCA AGAGTTCCCC TGAGAGTCCT CTCCAGAGTC CTGTGATCTC CTTCTCCTCC
TCCACTTCAT TGAGCCCATT CAGTGAAGAG TCCAGCAGCC CAGTAGATGA ATATACAAGT
TCCTCAGACA CCTTGCTAGA GAGTGATTCC TTGACAGACA GCGAGTCCTT GATAGAGAGC
GAGCCCTTGT TCACTTATAC ACTGGATGAA AAGGTGGACG AGTTGGCGCG GTTTCTTCTC
CTCAAATATC AAGTGAAGCA GCCTATCACA AAGGCAGAGA TGCTGACGAA TGTCATCAGC
AGGTACACGG GCTACTTTCC TGTGATCTTC AGGAAAGCCC GTGAGTTCAT AGAGATACTT
TTTGGCATTT CCCTGAGAGA AGTGGACCCT GATGACTCCT ATGTCTTTGT AAACACATTA
GACCTCACCT CTGAGGGGTG TCTGAGTGAT GAGCAGGGCA TGTCCCAGAA CCGCCTCCTG
ATTCTTATTC TGAGTATCAT CTTCATAAAG GGCACCTATG CCTCTGAGGA GGTCATCTGG
GATGTGCTGA GTGGAATAGG GGTGCGTGCT GGGAGGGAGC ACTTTGCCTT TGGGGAGCCC
AGGGAGCTCC TCACTAAAGT TTGGGTGCAG GAACATTACC TAGAGTACCG GGAGGTGCCC
AACTCTTCTC CTCCTCGTTA CGAATTCCTG TGGGGTCCAA GAGCTCATTC AGAAGTCATT
AAGAGGAAAG TAGTAGAGTT TTTGGCCATG CTAAAGAATA CCGTCCCTAT TACCTTTCCA
TCCTCTTACA AGGATGCTTT GAAAGATGTG GAAGAGAGAG CCCAGGCCAT AATTGACACC
ACAGATGATT CGACTGCCAC AGAAAGTGCA AGCTCCAGTG TCATGTCCCC CAGCTTCTCT
TCTGAGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

book

The expression of MAGE-C1 and MAGE-C2 in breast cancer and their clinical significance.
American journal of surgery211(1)142-51(2016 Jan)
Hou S,Sang M,Zhao L,Hou R,Shan B


book

The use of MAGE C1 and flow cytometry to determine the malignant cell type in multiple myeloma.
PloS one10(3)e0120734(2015)
Wienand K,Shires K


book

Intratumoral Heterogeneity of MAGE-C1/CT7 and MAGE-C2/CT10 Expression in Mucosal Melanoma.
BioMed research international2015432479(2015)
Curioni-Fontecedro A,Pitocco R,Schoenewolf NL,Holzmann D,Soldini D,Dummer R,Calvieri S,Moch H,Mihic-Probst D,Fitsche A


book

YKL-40 downregulation is a key factor to overcome temozolomide resistance in a glioblastoma cell line.
Oncology reports32(1)159-66(2014 Jul)
Akiyama Y,Ashizawa T,Komiyama M,Miyata H,Oshita C,Omiya M,Iizuka A,Kume A,Sugino T,Hayashi N,Mitsuya K,Nakasu Y,Yamaguchi K


book

Is there any relationship between gene expression of tumor antigens and CD4+ T cells in multiple myeloma?
Immunotherapy6(5)569-75(2014)
Braga WM,da Silva BR,Alves VL,Bortoluzo AB,Atanackovic D,Colleoni GW


 
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