Gene Symbol | DOP1B |
Entrez Gene ID | 9980 |
Full Name | dopey family member 2 |
Synonyms | 21orf5,C21orf5 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » DOP1B cDNA ORF clone
Gene Symbol | DOP1B |
Entrez Gene ID | 9980 |
Full Name | dopey family member 2 |
Synonyms | 21orf5,C21orf5 |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
XM_017028509.1 | XP_016883998.1 | protein dopey-2 isoform X1 |
NM_001320714.1 | NP_001307643.1 | protein dopey-2 |
NM_005128.3 | NP_005119.2 | protein dopey-2 |
Rattus norvegicus (Norway rat) | Dopey2 | NP_001178589.1 |
Canis lupus familiaris (dog) | DOPEY2 | XP_005638954.1 |
Gallus gallus (chicken) | DOPEY2 | XP_003640541.1 |
Xenopus tropicalis (tropical clawed frog) | dopey2 | XP_004912180.1 |
Homo sapiens (human) | DOPEY2 | NP_005119.2 |
DOPEY2 | XP_001084653.2 | |
Bos taurus (cattle) | DOPEY2 | XP_005202180.1 |
Pan troglodytes (chimpanzee) | DOPEY2 | XP_531552.2 |
Mus musculus (house mouse) | Dopey2 | NP_081569.1 |
Analysis of copy number variation in Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals.
Swaminathan S, Huentelman MJ, Corneveaux JJ, Myers AJ, Faber KM, Foroud T, Mayeux R, Shen L, Kim S, Turk M, Hardy J, Reiman EM, Saykin AJ,
PloS one7(12)e50640(2012)
A quantitative assessment of gene expression (QAGE) reveals differential overexpression of DOPEY2, a candidate gene for mental retardation, in Down syndrome brain regions.
Rachidi M, Delezoide AL, Delabar JM, Lopes C
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience27(4)393-8(2009 Jun)
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT).
Gonzalez-Begne M, Lu B, Han X, Hagen FK, Hand AR, Melvin JE, Yates JR
Journal of proteome research8(3)1304-14(2009 Mar)
Large-scale proteomics and phosphoproteomics of urinary exosomes.
Gonzales PA, Pisitkun T, Hoffert JD, Tchapyjnikov D, Star RA, Kleta R, Wang NS, Knepper MA
Journal of the American Society of Nephrology : JASN20(2)363-79(2009 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
Results quantify and statistically analyze, for the first time, DOPEY2 expression variations in different regions of the Down syndrome human fetal brains and to compare them to corresponding normal brains.
Title: A quantitative assessment of gene expression (QAGE) reveals differential overexpression of DOPEY2, a candidate gene for mental retardation, in Down syndrome brain regions.
C21orf5 selective expression in the key brain structures for learning and memory suggests that C21orf5 overexpression could participate in mental retardation pathogenesis in Down syndrome patients.
Title: C21orf5, a human candidate gene for brain abnormalities and mental retardation in Down syndrome.
C21orf5, could play a role in brain morphogenesis and, when overexpressed, it could participate in neurological features and mental retardation observed in DS patients.
Title: C21orf5, a new member of Dopey family involved in morphogenesis, could participate in neurological alterations and mental retardation in Down syndrome.
The differentially expressed C21orf5 gene in the medial temporal-lobe system could play a role in Down syndrome.
Title: The differentially expressed C21orf5 gene in the medial temporal-lobe system could play a role in mental retardation in Down syndrome and transgenic mice.
The following DOP1B gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DOP1B cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu93336 | |
Clone ID Related Accession (Same CDS sequence) | XM_017028509.1 | |
Accession Version | XM_017028509.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 6243bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | protein dopey-2 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000021.9) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTGGGGA CCAATCACCA ACTCACGGTG AAGTCTTTGC GTGCCTCCCT GTTGGACTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016883998.1 |
CDS | 237..6479 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017028509.1 |
1 | ATGCTGGGGA CCAATCACCA ACTCACGGTG AAGTCTTTGC GTGCCTCCCT GTTGGACTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu53351 | |
Clone ID Related Accession (Same CDS sequence) | NM_001320714.1 , NM_005128.3 | |
Accession Version | NM_001320714.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 6897bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-28 | |
Organism | Homo sapiens(human) | |
Product | protein dopey-2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BP365117.1, AP000689.1, BP364624.1, AB023150.2, AP000690.1, AP000691.1, AP000692.1 and W15495.1. On Mar 4, 2016 this sequence version replaced XM_006724068.1. Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.258545.1, SRR1803612.242730.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968540, SAMEA1968832 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## RefSeq Select criteria :: based on conservation, expression, longest protein ##RefSeq-Attributes-END## |
1 | ATGGATCCAG AAGAGCAGGA GCTCTTAAAT GATTACAGAT ACAGAAGCTA CTCTTCAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001307643.1 |
CDS | 189..7085 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001320714.1 |
1 | ATGGATCCAG AAGAGCAGGA GCTCTTAAAT GATTACAGAT ACAGAAGCTA CTCTTCAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu53351 | |
Clone ID Related Accession (Same CDS sequence) | NM_001320714.1 , NM_005128.3 | |
Accession Version | NM_005128.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 6897bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Homo sapiens(human) | |
Product | protein dopey-2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AJ237839.2, AP000690.1, AP000691.1, BC012791.2 and W15495.1. On Dec 23, 2014 this sequence version replaced NM_005128.2. Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Variants 1 and 2 encode the same protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AJ237839.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2163459, SAMN03465416 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGATCCAG AAGAGCAGGA GCTCTTAAAT GATTACAGAT ACAGAAGCTA CTCTTCAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_005119.2 |
CDS | 80..6976 |
Translation |
Target ORF information:
Target ORF information:
|
NM_005128.3 |
1 | ATGGATCCAG AAGAGCAGGA GCTCTTAAAT GATTACAGAT ACAGAAGCTA CTCTTCAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Analysis of copy number variation in Alzheimer's disease in a cohort of clinically characterized and neuropathologically verified individuals. |
A quantitative assessment of gene expression (QAGE) reveals differential overexpression of DOPEY2, a candidate gene for mental retardation, in Down syndrome brain regions. |
Proteomic analysis of human parotid gland exosomes by multidimensional protein identification technology (MudPIT). |
Large-scale proteomics and phosphoproteomics of urinary exosomes. |