Gene Symbol | Yars |
Entrez Gene ID | 107271 |
Full Name | tyrosyl-tRNA synthetase |
Synonyms | AL024047,AU018965 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Yars cDNA ORF clone
Gene Symbol | Yars |
Entrez Gene ID | 107271 |
Full Name | tyrosyl-tRNA synthetase |
Synonyms | AL024047,AU018965 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_134151.4 | NP_598912.4 | tyrosine--tRNA ligase, cytoplasmic |
NM_134151.5 | NP_598912.5 | tyrosine--tRNA ligase, cytoplasmic |
Saccharomyces cerevisiae (baker's yeast) | TYS1 | NP_011701.3 |
Kluyveromyces lactis | KLLA0F15389g | XP_455771.1 |
Oryza sativa (rice) | Os04g0303900 | NP_001052413.1 |
Neurospora crassa | NCU07755 | XP_958548.2 |
Homo sapiens (human) | YARS | NP_003671.1 |
Pan troglodytes (chimpanzee) | YARS | XP_001164500.1 |
YARS | XP_001104797.2 | |
Mus musculus (house mouse) | Yars | NP_598912.4 |
Rattus norvegicus (Norway rat) | Yars | NP_001020867.2 |
Gallus gallus (chicken) | YARS | NP_001006314.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP003003 | XP_311880.3 |
Schizosaccharomyces pombe (fission yeast) | yrs1 | NP_587876.1 |
Xenopus tropicalis (tropical clawed frog) | yars | NP_001004987.1 |
Canis lupus familiaris (dog) | YARS | XP_535324.4 |
Bos taurus (cattle) | YARS | NP_776645.1 |
Danio rerio (zebrafish) | yars | NP_958473.1 |
Eremothecium gossypii | AGOS_AAL148W | NP_982394.1 |
Drosophila melanogaster (fruit fly) | Aats-tyr | NP_648895.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_02449 | XP_003709239.1 |
Tyrosyl-tRNA synthetase: A potential kyotorphin synthetase in mammals.
Tsukahara T, Yamagishi S, Neyama H, Ueda H
Peptides10160-68(2017 Dec)
High-throughput discovery of novel developmental phenotypes.
Dickinson ME, Flenniken AM, Ji X, Teboul L, Wong MD, White JK, Meehan TF, Weninger WJ, Westerberg H, Adissu H, Baker CN, Bower L, Brown JM, Caddle LB, Chiani F, Clary D, Cleak J, Daly MJ, Denegre JM, Doe B, Dolan ME, Edie SM, Fuchs H, Gailus-Durner V, Galli A, Gambadoro A, Gallegos J, Guo S, Horner NR, Hsu CW, Johnson SJ, Kalaga S, Keith LC, Lanoue L, Lawson TN, Lek M, Mark M, Marschall S, Mason J, McElwee ML, Newbigging S, Nutter LM, Peterson KA, Ramirez-Solis R, Rowland DJ, Ryder E, Samocha KE, Seavitt JR, Selloum M, Szoke-Kovacs Z, Tamura M, Trainor AG, Tudose I, Wakana S, Warren J, Wendling O, West DB, Wong L, Yoshiki A, , , , , , , , , MacArthur DG, Tocchini-Valentini GP, Gao X, Flicek P, Bradley A, Skarnes WC, Justice MJ, Parkinson HE, Moore M, Wells S, Braun RE, Svenson KL, de Angelis MH, Herault Y, Mohun T, Mallon AM, Henkelman RM, Brown SD, Adams DJ, Lloyd KC, McKerlie C, Beaudet AL, Bu?an M, Murray SA
Nature537(7621)508-514(2016 09)
Oxidative stress diverts tRNA synthetase to nucleus for protection against DNA damage.
Wei N, Shi Y, Truong LN, Fisch KM, Xu T, Gardiner E, Fu G, Hsu YS, Kishi S, Su AI, Wu X, Yang XL
Molecular cell56(2)323-32(2014 Oct)
Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy.
Jordanova A, Irobi J, Thomas FP, Van Dijck P, Meerschaert K, Dewil M, Dierick I, Jacobs A, De Vriendt E, Guergueltcheva V, Rao CV, Tournev I, Gondim FA, D'Hooghe M, Van Gerwen V, Callaerts P, Van Den Bosch L, Timmermans JP, Robberecht W, Gettemans J, Thevelein JM, De Jonghe P, Kremensky I, Timmerman V
Nature genetics38(2)197-202(2006 Feb)
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Stryke D, Kawamoto M, Huang CC, Johns SJ, King LA, Harper CA, Meng EC, Lee RE, Yee A, L'Italien L, Chuang PT, Young SG, Skarnes WC, Babbitt PC, Ferrin TE
Nucleic acids research31(1)278-81(2003 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The following Yars gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Yars cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu16973 | |
Clone ID Related Accession (Same CDS sequence) | NM_134151.4 | |
Accession Version | NM_134151.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1695bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-22 | |
Organism | Mus musculus(house mouse) | |
Product | tyrosine--tRNA ligase, cytoplasmic | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY287648.1, AK145356.1 and AK076634.1. On Jan 16, 2008 this sequence version replaced NM_134151.3. ##Evidence-Data-START## Transcript exon combination :: AK076634.1, AK145356.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCAACCCG ACGGGACTAG CGTGACAGTT CCCGGCACGC GGAGACGACG GCGAACGAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_598912.4 |
CDS | 114..1808 |
Translation |
Target ORF information:
Target ORF information:
|
NM_134151.4 |
1 | ATGCAACCCG ACGGGACTAG CGTGACAGTT CCCGGCACGC GGAGACGACG GCGAACGAGG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu84850 | |
Clone ID Related Accession (Same CDS sequence) | NM_134151.5 | |
Accession Version | NM_134151.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1587bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-06-08 | |
Organism | Mus musculus(house mouse) | |
Product | tyrosine--tRNA ligase, cytoplasmic | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL606977.28. On Mar 18, 2019 this sequence version replaced NM_134151.4. Transcript Variant: This variant (1) represents the protein-coding transcript. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AK145356.1, SRR7345562.2632377.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## CDS uses downstream in-frame AUG :: upstream AUG and CDS extension is not conserved ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGGTGATG CTCCAAGCCC TGAGGAGAAG CTGCATCTTA TCACCCGGAA CCTGCAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_598912.5 |
CDS | 114..1700 |
Translation |
Target ORF information:
Target ORF information:
|
NM_134151.5 |
1 | ATGGGTGATG CTCCAAGCCC TGAGGAGAAG CTGCATCTTA TCACCCGGAA CCTGCAGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Tyrosyl-tRNA synthetase: A potential kyotorphin synthetase in mammals. |
High-throughput discovery of novel developmental phenotypes. |
Oxidative stress diverts tRNA synthetase to nucleus for protection against DNA damage. |
Disrupted function and axonal distribution of mutant tyrosyl-tRNA synthetase in dominant intermediate Charcot-Marie-Tooth neuropathy. |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |