Elac1 cDNA ORF clone, Mus musculus(house mouse)

Gene
Clones
gRNAs

Gene Symbol	Elac1
Entrez Gene ID	114615
Full Name	elaC ribonuclease Z 1
Synonyms	2610018O07Rik,8430417G19Rik
General protein information	Preferred Names elaC ribonuclease Z 1 Names zinc phosphodiesterase ELAC protein 1 RNase Z 1 elaC homolog 1 elaC homolog protein 1 ribonuclease Z 1 tRNA 3 endonuclease 1 tRNase Z 1
Gene Type	protein-coding
Organism	Mus musculus(house mouse)
Genome	Chromosome: 18 Map Location: 18\|18 E2

mRNA and Protein(s)

mRNA Protein Name

XM_030250276.1 XP_030106136.1 zinc phosphodiesterase ELAC protein 1 isoform X1

NM_053255.3 NP_444485.2 zinc phosphodiesterase ELAC protein 1
Pathways from BioSystems

mRNA	Protein	Name
XM_030250276.1	XP_030106136.1	zinc phosphodiesterase ELAC protein 1 isoform X1
NM_053255.3	NP_444485.2	zinc phosphodiesterase ELAC protein 1

Homologies

Danio rerio (zebrafish)	elac1	NP_001003503.1
Homo sapiens (human)	ELAC1	NP_061166.1
Bos taurus (cattle)	ELAC1	NP_001039792.1
Xenopus tropicalis (tropical clawed frog)	elac1	NP_001017028.1
Canis lupus familiaris (dog)	ELAC1	XP_849493.2
Rattus norvegicus (Norway rat)	Elac1	NP_001100876.1
Pan troglodytes (chimpanzee)	ELAC1	XP_003315964.1
Mus musculus (house mouse)	Elac1	NP_444485.2

Gene Ontology
Bibliography

Related articles in PubMed

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
Liu X, Jiao Y, Cao Y, Deng N, Ma Y, Hasty KA, Kang A, Chen H, Stuart JM, Gu W
BMC immunology17(1)25(2016 08)

Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development.
Wang B, Harrison W, Overbeek PA, Zheng H
Development (Cambridge, England)138(20)4487-97(2011 Oct)

A candidate prostate cancer susceptibility gene at chromosome 17p.
Tavtigian SV, Simard J, Teng DH, Abtin V, Baumgard M, Beck A, Camp NJ, Carillo AR, Chen Y, Dayananth P, Desrochers M, Dumont M, Farnham JM, Frank D, Frye C, Ghaffari S, Gupte JS, Hu R, Iliev D, Janecki T, Kort EN, Laity KE, Leavitt A, Leblanc G, McArthur-Morrison J, Pederson A, Penn B, Peterson KT, Reid JE, Richards S, Schroeder M, Smith R, Snyder SC, Swedlund B, Swensen J, Thomas A, Tranchant M, Woodland AM, Labrie F, Skolnick MH, Neuhausen S, Rommens J, Cannon-Albright LA
Nature genetics27(2)172-80(2001 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following Elac1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Elac1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OMu09443	NM_053255.3 Latest version!	Mus musculus elaC ribonuclease Z 1 (Elac1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$223.30 $319.00
OMu72393	XM_030250276.1 Latest version!	Mus musculus elaC ribonuclease Z 1 (Elac1), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$139.30 $199.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

Elac1 ( NM_053255.3 ) cDNA ORF clone, Mus musculus(house mouse) -> NP_444485.2 Mus musculus elaC ribonuclease Z 1 (Elac1), mRNA.

Price & Availability↑

CloneID	OMu09443
Clone ID Related Accession (Same CDS sequence)	NM_053255.3
Accession Version	NM_053255.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-01-19
Organism	Mus musculus(house mouse)
Product	zinc phosphodiesterase ELAC protein 1
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY286576.1, AF308697.1, CV556353.1, AK018424.1 and AC132418.3. On Aug 2, 2006 this sequence version replaced NM_053255.2. ##Evidence-Data-START## Transcript exon combination :: AF308697.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGTCTATGG ATGTGACCTT TCTTGGGACA GGAGCAGCAT ATCCATCACC GACCCGTGGC 
GCCTCTGCGG TGGTTCTTCG GTGCGAGGGC GAGTGCTGGC TCTTTGACTG TGGGGAGGGA 
ACACAGACCC AGCTTATGAA AAGCCAGCTT AAAGCAGGGA GAATTACCAA GATCTTCATC 
ACACATCTCC ATGGCGACCA CTTCTTTGGC CTTCCAGGCC TCCTCTGTAC CATCAGCCTG 
CAGAGTGGCT CTGTGGTCGC CAGGCAGCCT ATTGAGATCT ACGGCCCCGT CGGGCTTCGG 
GACTTTATCT GGAGAACCAT GGAGCTCTCT CACACGGAGT TGGTGTTTCC TTACGTGGTT 
CACGAGCTAG TTCCTACAGC TGACCAGTGT CCTGTAGAAG AACTGAGAGA ATTTGCACAC 
ATGGATGAAA CAGACAGCTC TCCCAAAGGA CAAGGACGAA CTATCTTGCT AGATGCAGAA 
GAAAACTCAT ACTGTCTGGT TGATGACGAG CAGTTTGTGG TAAAAGCATT TCGCCTCTTT 
CATAGAATTC CATCCTTTGG CTTTTCAGTT GTGGAAAAGA AGCGTGCAGG TAAACTCAAC 
GCACAGAAGC TGAGAGATCT CGGTGTGCCA CCAGGTCCTG CCTATGGGAA GCTGAAAAAC 
GGAATTTCTG TTGTTTTGGA TAATGGAGTT ACAATTTCTC CCCAAGACGT CTTAAAAAAG 
CCTATGGTTG GAAGAAAAGT TTGCATCCTG GGTGACTGTT CTGGGGTTGT GGGTGACGGG 
GGCGTGAAGC TGTGCTTTGA GGCCGACCTG CTGATCCACG AGGCCACTCT GGATGATTCC 
CAGATGGACA AAGCGAGAGA GCACGGCCAC AGCACGCCGC AGATGGCAGC GGCGTTTGCA 
AAGCTGTGCC GTGCCAAGAG GCTAGTTCTG ACCCACTTCA GTCAGAGGTA CAAACCAACC 
GCCTTGGCGA GAGAAGGGGA GGCAGACGGC ATCGCAGAGC TGAGGAAGCA AGCAGAGGCC 
GTGTTAGAGC TCCAAGAAGT GACTCTAGCA GAAGATTTTA TGGTGATCGG CATTCCGATC 
AAGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_444485.2
CDS	87..1175
Translation	MSMDVTFLGTGAAYPSPTRGASAVVLRCEGECWLFDCGEGTQTQLMKSQLKAGRITKIFITHLHGDHFFGLPGLLCTISLQSGSVVARQPIEIYGPVGLRDFIWRTMELSHTELVFPYVVHELVPTADQCPVEELREFAHMDETDSSPKGQGRTILLDAEENSYCLVDDEQFVVKAFRLFHRIPSFGFSVVEKKRAGKLNAQKLRDLGVPPGPAYGKLKNGISVVLDNGVTISPQDVLKKPMVGRKVCILGDCSGVVGDGGVKLCFEADLLIHEATLDDSQMDKAREHGHSTPQMAAAFAKLCRAKRLVLTHFSQRYKPTALAREGEADGIAELRKQAEAVLELQEVTLAEDFMVIGIPIKK

Target ORF information:

RefSeq Version	NM_053255.3
Organism	Mus musculus(house mouse)
Definition	Mus musculus elaC ribonuclease Z 1 (Elac1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_053255.3

ORF Insert Sequence:

ATGTCTATGG ATGTGACCTT TCTTGGGACA GGAGCAGCAT ATCCATCACC GACCCGTGGC 
GCCTCTGCGG TGGTTCTTCG GTGCGAGGGC GAGTGCTGGC TCTTTGACTG TGGGGAGGGA 
ACACAGACCC AGCTTATGAA AAGCCAGCTT AAAGCAGGGA GAATTACCAA GATCTTCATC 
ACACATCTCC ATGGCGACCA CTTCTTTGGC CTTCCAGGCC TCCTCTGTAC CATCAGCCTG 
CAGAGTGGCT CTGTGGTCGC CAGGCAGCCT ATTGAGATCT ACGGCCCCGT CGGGCTTCGG 
GACTTTATCT GGAGAACCAT GGAGCTCTCT CACACGGAGT TGGTGTTTCC TTACGTGGTT 
CACGAGCTAG TTCCTACAGC TGACCAGTGT CCTGTAGAAG AACTGAGAGA ATTTGCACAC 
ATGGATGAAA CAGACAGCTC TCCCAAAGGA CAAGGACGAA CTATCTTGCT AGATGCAGAA 
GAAAACTCAT ACTGTCTGGT TGATGACGAG CAGTTTGTGG TAAAAGCATT TCGCCTCTTT 
CATAGAATTC CATCCTTTGG CTTTTCAGTT GTGGAAAAGA AGCGTGCAGG TAAACTCAAC 
GCACAGAAGC TGAGAGATCT CGGTGTGCCA CCAGGTCCTG CCTATGGGAA GCTGAAAAAC 
GGAATTTCTG TTGTTTTGGA TAATGGAGTT ACAATTTCTC CCCAAGACGT CTTAAAAAAG 
CCTATGGTTG GAAGAAAAGT TTGCATCCTG GGTGACTGTT CTGGGGTTGT GGGTGACGGG 
GGCGTGAAGC TGTGCTTTGA GGCCGACCTG CTGATCCACG AGGCCACTCT GGATGATTCC 
CAGATGGACA AAGCGAGAGA GCACGGCCAC AGCACGCCGC AGATGGCAGC GGCGTTTGCA 
AAGCTGTGCC GTGCCAAGAG GCTAGTTCTG ACCCACTTCA GTCAGAGGTA CAAACCAACC 
GCCTTGGCGA GAGAAGGGGA GGCAGACGGC ATCGCAGAGC TGAGGAAGCA AGCAGAGGCC 
GTGTTAGAGC TCCAAGAAGT GACTCTAGCA GAAGATTTTA TGGTGATCGG CATTCCGATC 
AAGAAATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

Elac1 ( XM_030250276.1 ) cDNA ORF clone, Mus musculus(house mouse) -> XP_030106136.1 Mus musculus elaC ribonuclease Z 1 (Elac1), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OMu72393
Clone ID Related Accession (Same CDS sequence)	XM_030250276.1
Accession Version	XM_030250276.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 666bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-08-07
Organism	Mus musculus(house mouse)
Product	zinc phosphodiesterase ELAC protein 1 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000084.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGTCTATGG ATGTGACCTT TCTTGGGACA GGAGCAGCAT ATCCATCACC GACCCGTGGC 
GCCTCTGCGG TGGTTCTTCG GTGCGAGGGC GAGTGCTGGC TCTTTGACTG TGGGGAGGGA 
ACACAGACCC AGCTTATGAA AAGCCAGCTT AAAGCAGGGA GAATTACCAA GATCTTCATC 
ACACATCTCC ATGGCGACCA CTTCTTTGGC CTTCCAGGCC TCCTCTGTAC CATCAGCCTG 
CAGAGTGGCT CTGTGGTCGC CAGGCAGCCT ATTGAGATCT ACGGCCCCGT CGGGCTTCGG 
GACTTTATCT GGAGAACCAT GGAGCTCTCT CACACGGAGT TGGTGTTTCC TTACGTGGTT 
CACGAGCTAG TTCCTACAGC TGACCAGTGT CCTGTAGAAG AACTGAGAGA ATTTGCACAC 
ATGGATGAAA CAGACAGCTC TCCCAAAGGA CAAGGACGAA CTATCTTGCT AGATGCAGAA 
GAAAACTCAT ACTGTCTGGT TGATGACGAG CAGTTTGTGG TAAAAGCATT TCGCCTCTTT 
CATAGAATTC CATCCTTTGG CTTTTCAGTT GTGGAAAAGA AGCGTGCAGG TAAACTCAAC 
GCACAGAAGC TGAGAGATCT CGGGTTTCAC TCTGTAGCCC AGGCTGGCCT ACAAGTCACG 
GTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_030106136.1
CDS	127..792
Translation	MSMDVTFLGTGAAYPSPTRGASAVVLRCEGECWLFDCGEGTQTQLMKSQLKAGRITKIFITHLHGDHFFGLPGLLCTISLQSGSVVARQPIEIYGPVGLRDFIWRTMELSHTELVFPYVVHELVPTADQCPVEELREFAHMDETDSSPKGQGRTILLDAEENSYCLVDDEQFVVKAFRLFHRIPSFGFSVVEKKRAGKLNAQKLRDLGFHSVAQAGLQVTV

Target ORF information:

RefSeq Version	XM_030250276.1
Organism	Mus musculus(house mouse)
Definition	Mus musculus elaC ribonuclease Z 1 (Elac1), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_030250276.1

ORF Insert Sequence:

ATGTCTATGG ATGTGACCTT TCTTGGGACA GGAGCAGCAT ATCCATCACC GACCCGTGGC 
GCCTCTGCGG TGGTTCTTCG GTGCGAGGGC GAGTGCTGGC TCTTTGACTG TGGGGAGGGA 
ACACAGACCC AGCTTATGAA AAGCCAGCTT AAAGCAGGGA GAATTACCAA GATCTTCATC 
ACACATCTCC ATGGCGACCA CTTCTTTGGC CTTCCAGGCC TCCTCTGTAC CATCAGCCTG 
CAGAGTGGCT CTGTGGTCGC CAGGCAGCCT ATTGAGATCT ACGGCCCCGT CGGGCTTCGG 
GACTTTATCT GGAGAACCAT GGAGCTCTCT CACACGGAGT TGGTGTTTCC TTACGTGGTT 
CACGAGCTAG TTCCTACAGC TGACCAGTGT CCTGTAGAAG AACTGAGAGA ATTTGCACAC 
ATGGATGAAA CAGACAGCTC TCCCAAAGGA CAAGGACGAA CTATCTTGCT AGATGCAGAA 
GAAAACTCAT ACTGTCTGGT TGATGACGAG CAGTTTGTGG TAAAAGCATT TCGCCTCTTT 
CATAGAATTC CATCCTTTGG CTTTTCAGTT GTGGAAAAGA AGCGTGCAGG TAAACTCAAC 
GCACAGAAGC TGAGAGATCT CGGGTTTCAC TCTGTAGCCC AGGCTGGCCT ACAAGTCACG 
GTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Decreased expression levels of Ifi genes is associated to the increased resistance to spontaneous arthritis disease in mice deficiency of IL-1RA.
BMC immunology17(1)25(2016 08)
Liu X,Jiao Y,Cao Y,Deng N,Ma Y,Hasty KA,Kang A,Chen H,Stuart JM,Gu W

Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development.
Development (Cambridge, England)138(20)4487-97(2011 Oct)
Wang B,Harrison W,Overbeek PA,Zheng H

A candidate prostate cancer susceptibility gene at chromosome 17p.
Nature genetics27(2)172-80(2001 Feb)
Tavtigian SV,Simard J,Teng DH,Abtin V,Baumgard M,Beck A,Camp NJ,Carillo AR,Chen Y,Dayananth P,Desrochers M,Dumont M,Farnham JM,Frank D,Frye C,Ghaffari S,Gupte JS,Hu R,Iliev D,Janecki T,Kort EN,Laity KE,Leavitt A,Leblanc G,McArthur-Morrison J,Pederson A,Penn B,Peterson KT,Reid JE,Richards S,Schroeder M,Smith R,Snyder SC,Swedlund B,Swensen J,Thomas A,Tranchant M,Woodland AM,Labrie F,Skolnick MH,Neuhausen S,Rommens J,Cannon-Albright LA

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Elac1 cDNA ORF clone, Mus musculus(house mouse)

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Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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