| Gene Symbol | Alas2 |
| Entrez Gene ID | 11656 |
| Full Name | aminolevulinic acid synthase 2, erythroid |
| Synonyms | ALAS,ALAS-E,ALASE,Alas-2 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
The following Alas2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Alas2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu21979 | |
| Clone ID Related Accession (Same CDS sequence) | NM_009653.3 | |
| Accession Version | NM_009653.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1764bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-12-25 | |
| Organism | Mus musculus(house mouse) | |
| Product | 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform a | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY035435.1, AK077610.1, AK002642.1 and M15268.1. On Aug 24, 2007 this sequence version replaced NM_009653.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK077610.1, AK002642.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGTGGCAG CAGCTATGTT GCTACGGTCC TGTCCAGTGC TCTCTCAGGG CCCCACAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_033783.1 |
| CDS | 85..1848 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_009653.3 |
1 | ATGGTGGCAG CAGCTATGTT GCTACGGTCC TGTCCAGTGC TCTCTCAGGG CCCCACAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu22087 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001102446.1 | |
| Accession Version | NM_001102446.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1719bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-10 | |
| Organism | Mus musculus(house mouse) | |
| Product | 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform b | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY035435.1, M15268.1 and AK002642.1. Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the end of an exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: M15268.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849382 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: reported by MitoCarta ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGGTGGCAG CAGCTATGTT GCTACGGTCC TGTCCAGTGC TCTCTCAGGG CCCCACAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001095916.1 |
| CDS | 85..1803 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001102446.1 |
1 | ATGGTGGCAG CAGCTATGTT GCTACGGTCC TGTCCAGTGC TCTCTCAGGG CCCCACAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OMu90356 | |
| Clone ID Related Accession (Same CDS sequence) | XM_030251199.1 | |
| Accession Version | XM_030251199.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1803bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-07 | |
| Organism | Mus musculus(house mouse) | |
| Product | 5-aminolevulinate synthase, erythroid-specific, mitochondrial isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000086.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGGCCAACA GCCCCACAAA AATGGACTTT GGGCTCAGGA TGGTGGCAGC AGCTATGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_030107059.1 |
| CDS | 50..1852 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_030251199.1 |
1 | ATGGCCAACA GCCCCACAAA AATGGACTTT GGGCTCAGGA TGGTGGCAGC AGCTATGTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Molecular dynamics analysis of the structural and dynamic properties of the functionally enhanced hepta-variant of mouse 5-aminolevulinate synthase. |
Intron 1 GATA site enhances ALAS2 expression indispensably during erythroid differentiation. |
Murine erythroid 5-aminolevulinate synthase: Truncation of a disordered N-terminal extension is not detrimental for catalysis. |
