Gene Symbol | Gjc3 |
Entrez Gene ID | 118446 |
Full Name | gap junction protein, gamma 3 |
Synonyms | Cx29,Gje1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Gjc3 cDNA ORF clone
Gene Symbol | Gjc3 |
Entrez Gene ID | 118446 |
Full Name | gap junction protein, gamma 3 |
Synonyms | Cx29,Gje1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_080450.4 | NP_536698.2 | gap junction gamma-3 protein |
NM_080450.5 | NP_536698.2 | gap junction gamma-3 protein |
MED12 regulates a transcriptional network of calcium-handling genes in the heart.
Baskin KK, Makarewich CA, DeLeon SM, Ye W, Chen B, Beetz N, Schrewe H, Bassel-Duby R, Olson EN
JCI insight2(14)(2017 Jul)
Expression of connexin29 and 32 in the penumbra region after traumatic brain injury of mice.
Moon Y, Choi SY, Kim K, Kim H, Sun W
Neuroreport21(18)1135-9(2010 Dec)
Dynamic expression of Cx47 in mouse brain development and in the cuprizone model of myelin plasticity.
Parenti R, Cicirata F, Zappal? A, Catania A, La Delia F, Cicirata V, Tress O, Willecke K
Glia58(13)1594-609(2010 Oct)
Mouse lens connexin23 (Gje1) does not form functional gap junction channels but causes enhanced ATP release from HeLa cells.
Sonntag S, S?hl G, Dobrowolski R, Zhang J, Theis M, Winterhager E, Bukauskas FF, Willecke K
European journal of cell biology88(2)65-77(2009 Feb)
Cx29 and Cx32, two connexins expressed by myelinating glia, do not interact and are functionally distinct.
Ahn M, Lee J, Gustafsson A, Enriquez A, Lancaster E, Sul JY, Haydon PG, Paul DL, Huang Y, Abrams CK, Scherer SS
Journal of neuroscience research86(5)992-1006(2008 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Induction of Cxs 29 and 32 in the injury border suggests that altered Cx expression may contribute to the propagation of injury-related and/or regeneration signals after acute brain injury.
Title: Expression of connexin29 and 32 in the penumbra region after traumatic brain injury of mice.
Cx23 seems to share functional properties with pannexin (hemi) channels rather than gap junction channels of other connexins.
Title: Mouse lens connexin23 (Gje1) does not form functional gap junction channels but causes enhanced ATP release from HeLa cells.
Homomeric interactions of Cx29 and Cx32 require other domains: the N-terminus, transmembrane domains, and extracellular loops. Substituting the intracellular loop and/or tail of Cx32 with those of Cx29 prevents Cx32 from forming functional gap junctions.
Title: Cx29 and Cx32, two connexins expressed by myelinating glia, do not interact and are functionally distinct.
Cx29 protein expression was absent from neural crest cells but appeared as neural crest cells generated precursors (embryonic day 12) both in vivo and in vitro. This identifies Cx29 as a novel marker for cells of the defined Schwann cell lineage.
Title: Analysis of connexin expression during mouse Schwann cell development identifies connexin29 as a novel marker for the transition of neural crest to precursor cells.
Findings demonstrated the requirement of Cx29 for normal cochlear functions and suggest that Cx29 is a new candidate gene for studying the auditory neuropathy.
Title: Connexin29 is highly expressed in cochlear Schwann cells, and it is required for the normal development and function of the auditory nerve of mice.
The following Gjc3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gjc3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu09661 | |
Clone ID Related Accession (Same CDS sequence) | NM_080450.4 , NM_080450.5 | |
Accession Version | NM_080450.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 810bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-09-12 | |
Organism | Mus musculus(House mouse) | |
Product | gap junction gamma-3 protein | |
Comment | PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC125212.3. On May 1, 2007 this sequence version replaced NM_080450.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK047368.1, AK147913.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849380, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCTTCTGC TGGAGTTGCC AATCAAGTGC AGGATGTGCG GCAGGTTCCT GAGACAGCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_536698.2 |
CDS | 63..872 |
Translation |
Target ORF information:
Target ORF information:
|
NM_080450.4 |
1 | ATGCTTCTGC TGGAGTTGCC AATCAAGTGC AGGATGTGCG GCAGGTTCCT GAGACAGCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu09661 | |
Clone ID Related Accession (Same CDS sequence) | NM_080450.4 , NM_080450.5 | |
Accession Version | NM_080450.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 810bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-09 | |
Organism | Mus musculus(house mouse) | |
Product | gap junction gamma-3 protein | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY741110.1, AK047368.1 and AW495171.1. On Oct 17, 2017 this sequence version replaced NM_080450.4. Transcript Variant: This variant (1) represents the longer, protein-coding transcript. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK147913.1, AK047368.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGCTTCTGC TGGAGTTGCC AATCAAGTGC AGGATGTGCG GCAGGTTCCT GAGACAGCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_536698.2 |
CDS | 202..1011 |
Translation |
Target ORF information:
Target ORF information:
|
NM_080450.5 |
1 | ATGCTTCTGC TGGAGTTGCC AATCAAGTGC AGGATGTGCG GCAGGTTCCT GAGACAGCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
MED12 regulates a transcriptional network of calcium-handling genes in the heart. |
Expression of connexin29 and 32 in the penumbra region after traumatic brain injury of mice. |
Dynamic expression of Cx47 in mouse brain development and in the cuprizone model of myelin plasticity. |
Mouse lens connexin23 (Gje1) does not form functional gap junction channels but causes enhanced ATP release from HeLa cells. |
Cx29 and Cx32, two connexins expressed by myelinating glia, do not interact and are functionally distinct. |