Gene Symbol | Bsn |
Entrez Gene ID | 12217 |
Full Name | bassoon |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Bsn cDNA ORF clone
Gene Symbol | Bsn |
Entrez Gene ID | 12217 |
Full Name | bassoon |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006511634.4 | XP_006511697.1 | protein bassoon isoform X1 |
XM_006511634.3 | XP_006511697.1 | protein bassoon isoform X1 |
NM_007567.2 | NP_031593.2 | protein bassoon |
BSN | XP_001094100.2 | |
Canis lupus familiaris (dog) | BSN | XP_541885.2 |
Mus musculus (house mouse) | Bsn | NP_031593.2 |
Homo sapiens (human) | BSN | NP_003449.2 |
Rattus norvegicus (Norway rat) | Bsn | NP_062019.2 |
Gallus gallus (chicken) | BSN | XP_004944501.1 |
Pan troglodytes (chimpanzee) | BSN | XP_516463.4 |
Bos taurus (cattle) | BSN | XP_002697122.2 |
Xenopus tropicalis (tropical clawed frog) | bsn | XP_002936530.2 |
Danio rerio (zebrafish) | LOC100004063 | XP_001920788.3 |
Multiple roles of integrin-?3 at the neuromuscular junction.
Ross JA, Webster RG, Lechertier T, Reynolds LE, Turmaine M, Bencze M, Jamshidi Y, Cetin H, Muntoni F, Beeson D, Hodilvala-Dilke K, Conti FJ
Journal of cell science130(10)1772-1784(2017 May)
Bassoon Controls Presynaptic Autophagy through Atg5.
Okerlund ND, Schneider K, Leal-Ortiz S, Montenegro-Venegas C, Kim SA, Garner LC, Waites CL, Gundelfinger ED, Reimer RJ, Garner CC
Neuron93(4)897-913.e7(2017 Feb)
Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice.
Nishimune H, Badawi Y, Mori S, Shigemoto K
Scientific reports627935(2016 Jun)
Bassoon speeds vesicle reloading at a central excitatory synapse.
Hallermann S, Fejtova A, Schmidt H, Weyhersm?ller A, Silver RA, Gundelfinger ED, Eilers J
Neuron68(4)710-23(2010 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These data establish Bassoon as a major regulator of the molecular composition of the presynaptic neurotransmitter release sites.
Title: Bassoon specifically controls presynaptic P/Q-type Ca(2+) channels via RIM-binding protein.
Authors conclude that bassoon promotes vesicular replenishment and, consequently, a large standing pool of readily releasable synaptic vesicles at the endbulb synapse.
Title: Bassoon-disruption slows vesicle replenishment and induces homeostatic plasticity at a CNS synapse.
a novel role for Bassoon and Piccolo as critical regulators of presynaptic ubiquitination and proteostasis.
Title: Bassoon and Piccolo maintain synapse integrity by regulating protein ubiquitination and degradation.
This studyy demonistrated that reduced bassoon expression or complete lack of full-length bassoon impaired sound encoding to a similar extent, which is consistent with the comparable reduction of the readily releasable vesicle pool
Title: Disruption of the presynaptic cytomatrix protein bassoon degrades ribbon anchorage, multiquantal release, and sound encoding at the hair cell afferent synapse.
phosphorylation-induced 14-3-3 binding to Bassoon modulates its anchoring to the presynaptic cytomatrix
Title: Regulation of presynaptic anchoring of the scaffold protein Bassoon by phosphorylation-dependent interaction with 14-3-3 adaptor proteins.
The following Bsn gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Bsn cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu18858 | |
Clone ID Related Accession (Same CDS sequence) | XM_006511634.4 , XM_006511634.3 , NM_007567.2 | |
Accession Version | NM_007567.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 11829bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-26 | |
Organism | Mus musculus(house mouse) | |
Product | protein bassoon | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY742476.1, AC137678.11, AK135719.1, AK129141.1 and AI836567.1. On Feb 6, 2007 this sequence version replaced NM_007567.1. CCDS Note: This CCDS ID represents the protein described in PMIDs: 21092860 and 12628168. This variant is inferred from the human ortholog which is supported by AF052224.1. It should be noted this transcript is predicted to undergo nonsense-mediated mRNA decay (NMD). However, the protein is represented because it was detected endogenously in PMID: 21092860. It is likely that the majority of transcripts representing this variant will undergo NMD, while some low level of NMD escape may allow for the expression of this protein. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## ##RefSeq-Attributes-START## inferred exon combination :: based on alignments, homology NMD candidate :: PMID: 21092860 ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGGCAACG AGGCCAGCCT GGAGGGCGGC GCGGGCGAAG GGCCGCTGCC GCCCGGAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_031593.2 |
CDS | 126..11954 |
Translation |
Target ORF information:
Target ORF information:
|
NM_007567.2 |
1 | ATGGGCAACG AGGCCAGCCT GGAGGGCGGC GCGGGCGAAG GGCCGCTGCC GCCCGGAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu18858 | |
Clone ID Related Accession (Same CDS sequence) | XM_006511634.4 , XM_006511634.3 , NM_007567.2 | |
Accession Version | XM_006511634.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 11829bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | protein bassoon isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006511634.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCAACG AGGCCAGCCT GGAGGGCGGC GCGGGCGAAG GGCCGCTGCC GCCCGGAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006511697.1 |
CDS | 162..11990 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006511634.4 |
1 | ATGGGCAACG AGGCCAGCCT GGAGGGCGGC GCGGGCGAAG GGCCGCTGCC GCCCGGAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu18858 | |
Clone ID Related Accession (Same CDS sequence) | XM_006511634.4 , XM_006511634.3 , NM_007567.2 | |
Accession Version | XM_006511634.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 11829bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | protein bassoon isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000075.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006511634.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGGCAACG AGGCCAGCCT GGAGGGCGGC GCGGGCGAAG GGCCGCTGCC GCCCGGAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006511697.1 |
CDS | 162..11990 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006511634.3 |
1 | ATGGGCAACG AGGCCAGCCT GGAGGGCGGC GCGGGCGAAG GGCCGCTGCC GCCCGGAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Multiple roles of integrin-?3 at the neuromuscular junction. |
Bassoon Controls Presynaptic Autophagy through Atg5. |
Dual-color STED microscopy reveals a sandwich structure of Bassoon and Piccolo in active zones of adult and aged mice. |
Bassoon speeds vesicle reloading at a central excitatory synapse. |