Gene Symbol | Cacnb4 |
Entrez Gene ID | 12298 |
Full Name | calcium channel, voltage-dependent, beta 4 subunit |
Synonyms | 3110038O15Rik,Cchb4,lh |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Cacnb4 cDNA ORF clone
gRNAs
Gene Symbol | Cacnb4 |
Entrez Gene ID | 12298 |
Full Name | calcium channel, voltage-dependent, beta 4 subunit |
Synonyms | 3110038O15Rik,Cchb4,lh |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_017315165.1 | XP_017170654.1 | voltage-dependent L-type calcium channel subunit beta-4 isoform X2 |
XM_006497641.3 | XP_006497704.1 | voltage-dependent L-type calcium channel subunit beta-4 isoform X1 |
XM_030247010.1 | XP_030102870.1 | voltage-dependent L-type calcium channel subunit beta-4 isoform X2 |
XM_006497642.4 | XP_006497705.1 | voltage-dependent L-type calcium channel subunit beta-4 isoform X2 |
XM_017315163.1 | XP_017170652.1 | voltage-dependent L-type calcium channel subunit beta-4 isoform X1 |
XM_006497641.4 | XP_006497704.1 | voltage-dependent L-type calcium channel subunit beta-4 isoform X1 |
XM_011239015.1 | XP_011237317.1 | voltage-dependent L-type calcium channel subunit beta-4 isoform X1 |
NM_001037099.2 | NP_001032176.1 | voltage-dependent L-type calcium channel subunit beta-4 isoform a |
NM_001285428.1 | NP_001272357.1 | voltage-dependent L-type calcium channel subunit beta-4 isoform e |
NM_001285426.1 | NP_001272355.1 | voltage-dependent L-type calcium channel subunit beta-4 isoform c |
XM_006497642.3 | XP_006497705.1 | voltage-dependent L-type calcium channel subunit beta-4 isoform X2 |
NM_001285427.1 | NP_001272356.1 | voltage-dependent L-type calcium channel subunit beta-4 isoform d |
NM_001355059.1 | NP_001341988.1 | voltage-dependent L-type calcium channel subunit beta-4 isoform f |
NM_146123.3 | NP_666235.1 | voltage-dependent L-type calcium channel subunit beta-4 isoform b |
Homo sapiens (human) | CACNB4 | NP_000717.2 |
Canis lupus familiaris (dog) | CACNB4 | XP_005632048.1 |
Rattus norvegicus (Norway rat) | Cacnb4 | NP_001099203.1 |
Drosophila melanogaster (fruit fly) | Ca-beta | NP_001260375.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008028 | XP_317433.4 |
Pan troglodytes (chimpanzee) | CACNB4 | XP_003309336.1 |
Mus musculus (house mouse) | Cacnb4 | NP_001032176.1 |
Caenorhabditis elegans (roundworm) | ccb-1 | NP_491193.2 |
Xenopus tropicalis (tropical clawed frog) | cacnb4 | NP_001135623.1 |
CACNB4 | XP_002798958.1 | |
Bos taurus (cattle) | CACNB4 | NP_001179033.1 |
Gallus gallus (chicken) | CACNB4 | NP_001001733.1 |
Danio rerio (zebrafish) | cacnb4a | NP_001106991.1 |
Loss of the calcium channel β4 subunit impairs parallel fibre volley and Purkinje cell firing in cerebellum of adult ataxic mice.
Benedetti B, Benedetti A, Flucher BE
The European journal of neuroscience43(11)1486-98(2016 06)
Modified autonomic regulation in mice mutated in the β4 subunit of the lh/lh calcium channel.
Murakami M, Suzuki T, Wu TW, Kuwasako K, Takahashi E, Watanabe H, Murakami AM, Miyoshi I, Yanagisawa T, Sasano H, Ono K, Ohba T
Biochemical and biophysical research communications461(2)200-5(2015 May)
Ion channel expression in the developing enteric nervous system.
Hirst CS, Foong JP, Stamp LA, Fegan E, Dent S, Cooper EC, Lomax AE, Anderson CR, Bornstein JC, Young HM, McKeown SJ
PloS one10(3)e0123436(2015)
The juvenile myoclonic epilepsy mutant of the calcium channel β(4) subunit displays normal nuclear targeting in nerve and muscle cells.
Etemad S, Campiglio M, Obermair GJ, Flucher BE
Channels (Austin, Tex.)8(4)334-43(2014)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Study demonstrates that the lack of the voltage-gated calcium channel beta4 subunit causes a decreased late development in cerebellar cortical networks, characterized by reduced parallel fibre-purkinje cell input, shorter purkinje cell dendrites and depressed purkinje cell output.
Title: Loss of the calcium channel β4 subunit impairs parallel fibre volley and Purkinje cell firing in cerebellum of adult ataxic mice.
The nuclear targeting properties of the truncated beta(4b(1-481)) subunit in tsA-201 cells, skeletal myotubes, and in hippocampal neurons, were investigated.
Title: The juvenile myoclonic epilepsy mutant of the calcium channel β(4) subunit displays normal nuclear targeting in nerve and muscle cells.
an alternatively spliced beta4 subunit of voltage-gated calcium channels lacking the variable N terminus (beta4e) is identified
Title: Differential neuronal targeting of a new and two known calcium channel β4 subunit splice variants correlates with their regulation of gene expression.
Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy
Title: Cacnb4 directly couples electrical activity to gene expression, a process defective in juvenile epilepsy.
Ca(v) beta(4) protein was detected throughout the developing cerebellum, particularly in the molecular layer, and in contrast to the other subunits, Ca(v) beta(4) was mainly detected in the molecular layer and the hilus of the hippocampus.
Title: Regional expression and subcellular localization of the voltage-gated calcium channel β subunits in the developing mouse brain.
The following Cacnb4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cacnb4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu14187 | |
Clone ID Related Accession (Same CDS sequence) | NM_001285428.1 | |
Accession Version | NM_001285428.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1005bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Mus musculus(house mouse) | |
Product | voltage-dependent L-type calcium channel subunit beta-4 isoform e | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK158606.1 and AL845467.3. Transcript Variant: This variant (5) differs in the 5' UTR, lacks a portion of the 5' coding region and uses a downstream start codon compared to variant 1. The resulting protein (isoform e) is shorter and has a distinct N-terminus compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK158606.1, SRR1660815.146301.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGTATCAG GAACATTCCG AGCAACTCCC ACAACAACAG CAAAACAGAA GCAGAAAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001272357.1 |
CDS | 544..1548 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGTATCAG GAACATTCCG AGCAACTCCC ACAACAACAG CAAAACAGAA GCAGAAAGTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu14170 | |
Clone ID Related Accession (Same CDS sequence) | NM_001285426.1 | |
Accession Version | NM_001285426.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1509bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Mus musculus(house mouse) | |
Product | voltage-dependent L-type calcium channel subunit beta-4 isoform c | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL928960.25 and AL845467.3. Transcript Variant: This variant (3) differs in the 5' UTR and CDS, and uses a downstream start codon compared to variant 1. The resulting protein (isoform c) has a shorter N-terminus compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGATGTGG TGGCCCGAGG CACCACGACC CGGAGGAGCA GGTTGAAAAG ATCGGATGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001272355.1 |
CDS | 115..1623 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGATGTGG TGGCCCGAGG CACCACGACC CGGAGGAGCA GGTTGAAAAG ATCGGATGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu14245 | |
Clone ID Related Accession (Same CDS sequence) | NM_001037099.2 | |
Accession Version | NM_001037099.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1560bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Mus musculus(house mouse) | |
Product | voltage-dependent L-type calcium channel subunit beta-4 isoform a | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL928960.25, AK147338.1, BB131344.2 and AK046400.1. On Oct 18, 2013 this sequence version replaced NM_001037099.1. Transcript Variant: This variant (1) encodes the longest protein (isoform a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK147338.1, SRR1660819.50657.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCGTCCT CGTACGGCAA GAACGGGGCG GCGGACGGGC CGCACTCCCC CAGCTCACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001032176.1 |
CDS | 280..1839 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTCGTCCT CGTACGGCAA GAACGGGGCG GCGGACGGGC CGCACTCCCC CAGCTCACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17140 | |
Clone ID Related Accession (Same CDS sequence) | XM_006497641.3 , XM_017315163.1 , XM_006497641.4 , XM_011239015.1 , NM_001285427.1 | |
Accession Version | NM_001285427.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1422bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Mus musculus(house mouse) | |
Product | voltage-dependent L-type calcium channel subunit beta-4 isoform d | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ128061.1, AK038633.1 and AL845467.3. Transcript Variant: This variant (4) differs in the 5' UTR and lacks a portion of the 5' coding region compared to variant 1. This results in the use of a downstream start codon. The resulting protein (isoform d) is shorter and has a distinct N-terminus compared to isoform a. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660819.178290.1, SRR1660813.258364.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGGCTGGGT CAGCAGATTC CTATACAAGC AGGCCATCGG ACTCCGATGT CTCCTTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001272356.1 |
CDS | 498..1919 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCTGGGT CAGCAGATTC CTATACAAGC AGGCCATCGG ACTCCGATGT CTCCTTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu29272 | |
Clone ID Related Accession (Same CDS sequence) | XM_017315165.1 , XM_030247010.1 , XM_006497642.4 , XM_006497642.3 , NM_001355059.1 | |
Accession Version | NM_001355059.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-28 | |
Organism | Mus musculus(house mouse) | |
Product | voltage-dependent L-type calcium channel subunit beta-4 isoform f | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL928960.25 and AL845467.3. On Sep 6, 2017 this sequence version replaced XM_017315165.1. Transcript Variant: This variant (6) differs in the 5' UTR and lacks a portion of the 5' coding region compared to variant 1. This results in the use of a downstream start codon. The resulting protein (isoform f) is shorter and has a distinct N-terminus compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660815.102348.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164142 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTGCCCGT TCCCAGCACA GCCATCTCCT TTGACGCCAA GGACTTTCTT CACATTAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001341988.1 |
CDS | 685..1788 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTGCCCGT TCCCAGCACA GCCATCTCCT TTGACGCCAA GGACTTTCTT CACATTAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17140 | |
Clone ID Related Accession (Same CDS sequence) | XM_006497641.3 , XM_017315163.1 , XM_006497641.4 , XM_011239015.1 , NM_001285427.1 | |
Accession Version | XM_006497641.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1422bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | voltage-dependent L-type calcium channel subunit beta-4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006497641.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTGGGT CAGCAGATTC CTATACAAGC AGGCCATCGG ACTCCGATGT CTCCTTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006497704.1 |
CDS | 389..1810 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCTGGGT CAGCAGATTC CTATACAAGC AGGCCATCGG ACTCCGATGT CTCCTTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17140 | |
Clone ID Related Accession (Same CDS sequence) | XM_006497641.3 , XM_017315163.1 , XM_006497641.4 , XM_011239015.1 , NM_001285427.1 | |
Accession Version | XM_017315163.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1422bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | voltage-dependent L-type calcium channel subunit beta-4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTGGGT CAGCAGATTC CTATACAAGC AGGCCATCGG ACTCCGATGT CTCCTTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017170652.1 |
CDS | 1756..3177 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCTGGGT CAGCAGATTC CTATACAAGC AGGCCATCGG ACTCCGATGT CTCCTTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17140 | |
Clone ID Related Accession (Same CDS sequence) | XM_006497641.3 , XM_017315163.1 , XM_006497641.4 , XM_011239015.1 , NM_001285427.1 | |
Accession Version | XM_011239015.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1422bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | voltage-dependent L-type calcium channel subunit beta-4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTGGGT CAGCAGATTC CTATACAAGC AGGCCATCGG ACTCCGATGT CTCCTTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011237317.1 |
CDS | 2156..3577 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCTGGGT CAGCAGATTC CTATACAAGC AGGCCATCGG ACTCCGATGT CTCCTTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu29272 | |
Clone ID Related Accession (Same CDS sequence) | XM_017315165.1 , XM_030247010.1 , XM_006497642.4 , XM_006497642.3 , NM_001355059.1 | |
Accession Version | XM_017315165.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(House mouse) | |
Product | voltage-dependent L-type calcium channel subunit beta-4 isoform X2 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGCCCGT TCCCAGCACA GCCATCTCCT TTGACGCCAA GGACTTTCTT CACATTAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017170654.1 |
CDS | 1058..2161 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTGCCCGT TCCCAGCACA GCCATCTCCT TTGACGCCAA GGACTTTCTT CACATTAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu29272 | |
Clone ID Related Accession (Same CDS sequence) | XM_017315165.1 , XM_030247010.1 , XM_006497642.4 , XM_006497642.3 , NM_001355059.1 | |
Accession Version | XM_006497642.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | voltage-dependent L-type calcium channel subunit beta-4 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006497642.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGCCCGT TCCCAGCACA GCCATCTCCT TTGACGCCAA GGACTTTCTT CACATTAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006497705.1 |
CDS | 898..2001 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTGCCCGT TCCCAGCACA GCCATCTCCT TTGACGCCAA GGACTTTCTT CACATTAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu14174 | |
Clone ID Related Accession (Same CDS sequence) | NM_146123.3 | |
Accession Version | NM_146123.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1461bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Mus musculus(house mouse) | |
Product | voltage-dependent L-type calcium channel subunit beta-4 isoform b | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL928960.25, AK038633.1, BC026479.1, AK147338.1, BB131344.2 and AK046400.1. On Oct 18, 2013 this sequence version replaced NM_146123.2. Transcript Variant: This variant (2) differs in the 5' UTR and lacks a portion of the 5' coding region compared to variant 1. This results in the use of a downstream start codon. The resulting protein (isoform b) is shorter and has a distinct N-terminus compared to isoform a. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660817.93971.1, SRR1660813.235858.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTATGACA ATTTGTACCT GCATGGAGTT GAAGACTCGG AGGCTGGGTC AGCAGATTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_666235.1 |
CDS | 299..1759 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGTATGACA ATTTGTACCT GCATGGAGTT GAAGACTCGG AGGCTGGGTC AGCAGATTCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu17140 | |
Clone ID Related Accession (Same CDS sequence) | XM_006497641.3 , XM_017315163.1 , XM_006497641.4 , XM_011239015.1 , NM_001285427.1 | |
Accession Version | XM_006497641.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1422bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | voltage-dependent L-type calcium channel subunit beta-4 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006497641.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGCTGGGT CAGCAGATTC CTATACAAGC AGGCCATCGG ACTCCGATGT CTCCTTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006497704.1 |
CDS | 390..1811 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGCTGGGT CAGCAGATTC CTATACAAGC AGGCCATCGG ACTCCGATGT CTCCTTGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu29272 | |
Clone ID Related Accession (Same CDS sequence) | XM_017315165.1 , XM_030247010.1 , XM_006497642.4 , XM_006497642.3 , NM_001355059.1 | |
Accession Version | XM_030247010.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | voltage-dependent L-type calcium channel subunit beta-4 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGCCCGT TCCCAGCACA GCCATCTCCT TTGACGCCAA GGACTTTCTT CACATTAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030102870.1 |
CDS | 414..1517 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTGCCCGT TCCCAGCACA GCCATCTCCT TTGACGCCAA GGACTTTCTT CACATTAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu29272 | |
Clone ID Related Accession (Same CDS sequence) | XM_017315165.1 , XM_030247010.1 , XM_006497642.4 , XM_006497642.3 , NM_001355059.1 | |
Accession Version | XM_006497642.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1104bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | voltage-dependent L-type calcium channel subunit beta-4 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000068.7) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006497642.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGCCCGT TCCCAGCACA GCCATCTCCT TTGACGCCAA GGACTTTCTT CACATTAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006497705.1 |
CDS | 910..2013 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTGCCCGT TCCCAGCACA GCCATCTCCT TTGACGCCAA GGACTTTCTT CACATTAAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Loss of the calcium channel β4 subunit impairs parallel fibre volley and Purkinje cell firing in cerebellum of adult ataxic mice. |
Modified autonomic regulation in mice mutated in the β4 subunit of the lh/lh calcium channel. |
Ion channel expression in the developing enteric nervous system. |
The juvenile myoclonic epilepsy mutant of the calcium channel β(4) subunit displays normal nuclear targeting in nerve and muscle cells. |