Gene Symbol | Calcr |
Entrez Gene ID | 12311 |
Full Name | calcitonin receptor |
Synonyms | Clr,Ct-r |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Calcr cDNA ORF clone
Gene Symbol | Calcr |
Entrez Gene ID | 12311 |
Full Name | calcitonin receptor |
Synonyms | Clr,Ct-r |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006504973.2 | XP_006505036.1 | calcitonin receptor isoform X2 |
XM_006504972.2 | XP_006505035.1 | calcitonin receptor isoform X1 |
NM_001355192.1 | NP_001342121.1 | calcitonin receptor isoform 1a precursor |
NM_007588.2 | NP_031614.2 | calcitonin receptor isoform 1b precursor |
NM_001377018.1 | NP_001363947.1 | calcitonin receptor isoform 1b precursor |
XM_006504972.1 | XP_006505035.1 | calcitonin receptor isoform X1 |
NM_001042725.1 | NP_001036190.1 | calcitonin receptor isoform 1a precursor |
Canis lupus familiaris (dog) | CALCR | NP_001184071.1 |
CALCR | XP_001099544.2 | |
Danio rerio (zebrafish) | calcr | XP_003200679.2 |
Homo sapiens (human) | CALCR | NP_001158209.1 |
Pan troglodytes (chimpanzee) | CALCR | XP_001167949.1 |
Bos taurus (cattle) | CALCR | NP_001069737.2 |
Mus musculus (house mouse) | Calcr | NP_031614.2 |
Rattus norvegicus (Norway rat) | Calcr | NP_446268.2 |
Gallus gallus (chicken) | CALCR | XP_425985.3 |
Xenopus tropicalis (tropical clawed frog) | calcr | XP_002934645.2 |
Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission.
Yarwood RE, Imlach WL, Lieu T, Veldhuis NA, Jensen DD, Klein Herenbrink C, Aurelio L, Cai Z, Christie MJ, Poole DP, Porter CJH, McLean P, Hicks GA, Geppetti P, Halls ML, Canals M, Bunnett NW
Proceedings of the National Academy of Sciences of the United States of America114(46)12309-12314(2017 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
upregulated in synovial tissue of osteoarthritic mice by macrophage-derived IL-1 beta
Title: Synovial macrophage-derived IL-1? regulates the calcitonin receptor in osteoarthritic mice.
Calcr knockout resulted in abnormal quiescent state of muscle stem cells, reduction of their pool apoptosis and relocation from the MSC niche.
Title: Calcitonin Receptor Signaling Inhibits Muscle Stem Cells from Escaping the Quiescent State and the Niche.
protects the maternal skeleton during lactation by a direct action on osteocytes to inhibit osteolysis
Title: A Role for the Calcitonin Receptor to Limit Bone Loss During Lactation in Female Mice by Inhibiting Osteocytic Osteolysis.
The relevance of the OPG/RANK/RANKL system in the particle-induced osteolysis process, was investigated.
Title: The role of calcitonin receptor signalling in polyethylene particle-induced osteolysis.
data suggest that Clr-b modulation is a conserved innate host cell response to virus infection that is subverted by multiple CMV immune evasion strategies.
Title: Modulation of Clr Ligand Expression and NKR-P1 Receptor Function during Murine Cytomegalovirus Infection.
The following Calcr gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Calcr cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu00997 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504973.2 , NM_001355192.1 , NM_001042725.1 | |
Accession Version | NM_001355192.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1491bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-22 | |
Organism | Mus musculus(house mouse) | |
Product | calcitonin receptor isoform 1a precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK138275.1, AK162391.1 and AK133983.1. On Sep 13, 2017 this sequence version replaced XM_006504973.2. Transcript Variant: This variant (3) lacks an alternate in-frame exon compared to variant 1b. The resulting isoform (1a), has the same N- and C-termini but is shorter compared to isoform 1b. Variants 1a and 3 encode the same protein (isoform 1a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK138275.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGACTCCAA GGAGGTCCAG AGTGAAAAGG CGGAATCTCC GCAAACCGAA GATGAGGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001342121.1 |
CDS | 555..2045 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001355192.1 |
1 | ATGACTCCAA GGAGGTCCAG AGTGAAAAGG CGGAATCTCC GCAAACCGAA GATGAGGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu00997 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504973.2 , NM_001355192.1 , NM_001042725.1 | |
Accession Version | NM_001042725.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1491bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-21 | |
Organism | Mus musculus(house mouse) | |
Product | calcitonin receptor isoform 1a precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK133983.1 and AC066688.4. Transcript Variant: This variant (1a, previously called b), differs in the 5' UTR and lacks an alternate in-frame exon compared to variant 1b. The resulting isoform (1a, previously called b), has the same N- and C-termini but is shorter compared to isoform 1b. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK133983.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164138 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGACTCCAA GGAGGTCCAG AGTGAAAAGG CGGAATCTCC GCAAACCGAA GATGAGGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001036190.1 |
CDS | 306..1796 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001042725.1 |
1 | ATGACTCCAA GGAGGTCCAG AGTGAAAAGG CGGAATCTCC GCAAACCGAA GATGAGGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu00997 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504973.2 , NM_001355192.1 , NM_001042725.1 | |
Accession Version | XM_006504973.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1491bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(House mouse) | |
Product | calcitonin receptor isoform X2 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006504973.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACTCCAA GGAGGTCCAG AGTGAAAAGG CGGAATCTCC GCAAACCGAA GATGAGGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006505036.1 |
CDS | 574..2064 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504973.2 |
1 | ATGACTCCAA GGAGGTCCAG AGTGAAAAGG CGGAATCTCC GCAAACCGAA GATGAGGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu00421 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504972.2 , NM_007588.2 , NM_001377018.1 , XM_006504972.1 | |
Accession Version | NM_007588.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1602bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Mus musculus(house mouse) | |
Product | calcitonin receptor isoform 1b precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CJ057218.1, AK162391.1 and AC066688.4. On Aug 12, 2006 this sequence version replaced NM_007588.1. Transcript Variant: This variant (1b), previously called a, represents the longer variant and encodes the longer isoform (1b, previously called a). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK039161.1, U18542.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849375, SAMN00849381 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGACTCCAA GGAGGTCCAG AGTGAAAAGG CGGAATCTCC GCAAACCGAA GATGAGGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_031614.2 |
CDS | 555..2156 |
Translation |
Target ORF information:
Target ORF information:
|
NM_007588.2 |
1 | ATGACTCCAA GGAGGTCCAG AGTGAAAAGG CGGAATCTCC GCAAACCGAA GATGAGGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu00421 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504972.2 , NM_007588.2 , NM_001377018.1 , XM_006504972.1 | |
Accession Version | NM_001377018.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1602bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2020-01-04 | |
Organism | Mus musculus(house mouse) | |
Product | calcitonin receptor isoform 1b precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC161368.2 and AC066688.4. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. |
1 | ATGACTCCAA GGAGGTCCAG AGTGAAAAGG CGGAATCTCC GCAAACCGAA GATGAGGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001363947.1 |
CDS | 306..1907 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001377018.1 |
1 | ATGACTCCAA GGAGGTCCAG AGTGAAAAGG CGGAATCTCC GCAAACCGAA GATGAGGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu00421 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504972.2 , NM_007588.2 , NM_001377018.1 , XM_006504972.1 | |
Accession Version | XM_006504972.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1602bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | calcitonin receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006504972.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACTCCAA GGAGGTCCAG AGTGAAAAGG CGGAATCTCC GCAAACCGAA GATGAGGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006505035.1 |
CDS | 535..2136 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504972.2 |
1 | ATGACTCCAA GGAGGTCCAG AGTGAAAAGG CGGAATCTCC GCAAACCGAA GATGAGGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu00421 | |
Clone ID Related Accession (Same CDS sequence) | XM_006504972.2 , NM_007588.2 , NM_001377018.1 , XM_006504972.1 | |
Accession Version | XM_006504972.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1602bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | calcitonin receptor isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGACTCCAA GGAGGTCCAG AGTGAAAAGG CGGAATCTCC GCAAACCGAA GATGAGGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006505035.1 |
CDS | 377..1978 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006504972.1 |
1 | ATGACTCCAA GGAGGTCCAG AGTGAAAAGG CGGAATCTCC GCAAACCGAA GATGAGGTTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Endosomal signaling of the receptor for calcitonin gene-related peptide mediates pain transmission. |