Gene Symbol | Csn3 |
Entrez Gene ID | 12994 |
Full Name | casein kappa |
Synonyms | AW208918,CSN10,Csnk |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Csn3 cDNA ORF clone
Gene Symbol | Csn3 |
Entrez Gene ID | 12994 |
Full Name | casein kappa |
Synonyms | AW208918,CSN10,Csnk |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006534765.2 | XP_006534828.1 | kappa-casein isoform X1 |
NM_001356571.1 | NP_001343500.1 | kappa-casein isoform b precursor |
NM_001356570.1 | NP_001343499.1 | kappa-casein isoform a precursor |
NM_007786.4 | NP_031812.2 | kappa-casein precursor |
NM_007786.5 | NP_031812.2 | kappa-casein isoform a precursor |
Csn3 gene is regulated by all-trans retinoic acid during neural differentiation in mouse P19 cells.
Komori R, Kobayashi T, Matsuo H, Kino K, Miyazawa H
PloS one8(4)e61938(2013)
A conditional knockout resource for the genome-wide study of mouse gene function.
Skarnes WC, Rosen B, West AP, Koutsourakis M, Bushell W, Iyer V, Mujica AO, Thomas M, Harrow J, Cox T, Jackson D, Severin J, Biggs P, Fu J, Nefedov M, de Jong PJ, Stewart AF, Bradley A
Nature474(7351)337-42(2011 Jun)
Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation.
Kim E, Yoon SJ, Kim EY, Kim Y, Lee HS, Kim KH, Lee KA
PloS one6(10)e25870(2011)
kappa-casein-deficient mice fail to lactate.
Shekar PC, Goel S, Rani SD, Sarathi DP, Alex JL, Singh S, Kumar S
Proceedings of the National Academy of Sciences of the United States of America103(21)8000-5(2006 May)
Mutagenesis of diploid mammalian genes by gene entrapment.
Lin Q, Donahue SL, Moore-Jarrett T, Cao S, Osipovich AB, Ruley HE
Nucleic acids research34(20)e139(2006)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
the Csn3 expression is upregulated via all-trans retinoic acid-bound RARalpha.
Title: Csn3 gene is regulated by all-trans retinoic acid during neural differentiation in mouse P19 cells.
CSN3 and CSN5 are involved in oocyte meiosis by regulating degradation of Cyclin B1 and Securin via APC/C.
Title: Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation.
kappa-casein has a role in mouse lactation
Title: kappa-casein-deficient mice fail to lactate.
The following Csn3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Csn3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu00804 | |
Clone ID Related Accession (Same CDS sequence) | XM_006534765.2 , NM_001356570.1 , NM_007786.4 , NM_007786.5 | |
Accession Version | NM_001356570.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-29 | |
Organism | Mus musculus(house mouse) | |
Product | kappa-casein isoform a precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC022298.31 and AK164788.1. On Oct 11, 2017 this sequence version replaced XM_006534765.2. Transcript Variant: This variant (2) differs in the 3' UTR compared to variant 1. Variants 1 and 2 both encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI250529.1, BI112544.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN01164134 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGATGAGGA ATTTTATCGT AGTTGTGAAT ATTCTGGCAT TAACTCTGCC CTTTTTGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001343499.1 |
CDS | 106..651 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001356570.1 |
1 | ATGATGAGGA ATTTTATCGT AGTTGTGAAT ATTCTGGCAT TAACTCTGCC CTTTTTGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu00804 | |
Clone ID Related Accession (Same CDS sequence) | XM_006534765.2 , NM_001356570.1 , NM_007786.4 , NM_007786.5 | |
Accession Version | NM_007786.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2015-02-14 | |
Organism | Mus musculus(House mouse) | |
Product | kappa-casein precursor | |
Comment | PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC022298.31. On Apr 27, 2007 this sequence version replaced NM_007786.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK142673.1, BY730915.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849375, SAMN01164134 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGATGAGGA ATTTTATCGT AGTTGTGAAT ATTCTGGCAT TAACTCTGCC CTTTTTGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_031812.2 |
CDS | 52..597 |
Translation |
Target ORF information:
Target ORF information:
|
NM_007786.4 |
1 | ATGATGAGGA ATTTTATCGT AGTTGTGAAT ATTCTGGCAT TAACTCTGCC CTTTTTGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu00804 | |
Clone ID Related Accession (Same CDS sequence) | XM_006534765.2 , NM_001356570.1 , NM_007786.4 , NM_007786.5 | |
Accession Version | NM_007786.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-25 | |
Organism | Mus musculus(house mouse) | |
Product | kappa-casein isoform a precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC022298.31 and AK142673.1. On Oct 11, 2017 this sequence version replaced NM_007786.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longer isoform (a). Variants 1 and 2 both encode the same isoform (a). Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AK142673.1, BY730915.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849375, SAMN01164134 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGATGAGGA ATTTTATCGT AGTTGTGAAT ATTCTGGCAT TAACTCTGCC CTTTTTGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_031812.2 |
CDS | 106..651 |
Translation |
Target ORF information:
Target ORF information:
|
NM_007786.5 |
1 | ATGATGAGGA ATTTTATCGT AGTTGTGAAT ATTCTGGCAT TAACTCTGCC CTTTTTGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu83833 | |
Clone ID Related Accession (Same CDS sequence) | NM_001356571.1 | |
Accession Version | NM_001356571.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 516bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-21 | |
Organism | Mus musculus(house mouse) | |
Product | kappa-casein isoform b precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC022298.31. Transcript Variant: This variant (3) differs in the 3' UTR and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (b) has the same N- and C-termini but is shorter compared to isoform a. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BI108989.1, BI452794.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849375, SAMN01164134 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGATGAGGA ATTTTATCGT AGTTGTGAAT ATTCTGGCAT TAACTCTGCC CTTTTTGTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001343500.1 |
CDS | 106..621 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001356571.1 |
1 | ATGATGAGGA ATTTTATCGT AGTTGTGAAT ATTCTGGCAT TAACTCTGCC CTTTTTGTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu00804 | |
Clone ID Related Accession (Same CDS sequence) | XM_006534765.2 , NM_001356570.1 , NM_007786.4 , NM_007786.5 | |
Accession Version | XM_006534765.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 546bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(House mouse) | |
Product | kappa-casein isoform X1 | |
Comment | MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Feb 9, 2015 this sequence version replaced XM_006534765.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGATGAGGA ATTTTATCGT AGTTGTGAAT ATTCTGGCAT TAACTCTGCC CTTTTTGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006534828.1 |
CDS | 110..655 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006534765.2 |
1 | ATGATGAGGA ATTTTATCGT AGTTGTGAAT ATTCTGGCAT TAACTCTGCC CTTTTTGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Csn3 gene is regulated by all-trans retinoic acid during neural differentiation in mouse P19 cells. |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Function of COP9 signalosome in regulation of mouse oocytes meiosis by regulating MPF activity and securing degradation. |
kappa-casein-deficient mice fail to lactate. |
Mutagenesis of diploid mammalian genes by gene entrapment. |