Gene Symbol | Erf |
Entrez Gene ID | 13875 |
Full Name | Ets2 repressor factor |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Erf cDNA ORF clone
gRNAs
Gene Symbol | Erf |
Entrez Gene ID | 13875 |
Full Name | Ets2 repressor factor |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_030242130.1 | XP_030097990.1 | ETS domain-containing transcription factor ERF isoform X2 |
XM_030242129.1 | XP_030097989.1 | ETS domain-containing transcription factor ERF isoform X2 |
XM_030242128.1 | XP_030097988.1 | ETS domain-containing transcription factor ERF isoform X1 |
NM_010155.3 | NP_034285.3 | ETS domain-containing transcription factor ERF |
Homo sapiens (human) | ERF | NP_006485.2 |
ERF | XP_001097678.2 | |
Bos taurus (cattle) | ERF | NP_001192394.1 |
Pan troglodytes (chimpanzee) | ERF | XP_003316428.1 |
Danio rerio (zebrafish) | erfl3 | XP_694263.4 |
Canis lupus familiaris (dog) | ERF | XP_003432625.1 |
Danio rerio (zebrafish) | erf | NP_001038392.1 |
Xenopus tropicalis (tropical clawed frog) | erf | NP_001015821.1 |
Mus musculus (house mouse) | Erf | NP_034285.3 |
Rattus norvegicus (Norway rat) | Erf | NP_001163806.1 |
The Ets2 Repressor Factor (Erf) Is Required for Effective Primitive and Definitive Hematopoiesis.
Peraki I, Palis J, Mavrothalassitis G
Molecular and cellular biology37(19)(2017 Oct)
ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis.
Bose R, Karthaus WR, Armenia J, Abida W, Iaquinta PJ, Zhang Z, Wongvipat J, Wasmuth EV, Shah N, Sullivan PS, Doran MG, Wang P, Patruno A, Zhao Y, , Zheng D, Schultz N, Sawyers CL
Nature546(7660)671-675(2017 06)
Early molecular events during retinoic acid induced differentiation of neuromesodermal progenitors.
Cunningham TJ, Colas A, Duester G
Biology open5(12)1821-1833(2016 Dec)
Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg.
Ohta Y, Okabe T, Larmour C, Di Rocco A, Maijenburg MW, Phillips A, Speck NA, Wakitani S, Nakamura T, Yamada Y, Enomoto-Iwamoto M, Pacifici M, Iwamoto M
Arthritis & rheumatology (Hoboken, N.J.)67(10)2679-90(2015 Oct)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Results provide evidence that Erf is required for both primitive and erythromyeloid progenitor waves of hematopoietic stem cell (HSC)-independent hematopoiesis as well as for the normal function of HSCs.
Title: The Ets2 Repressor Factor (Erf) Is Required for Effective Primitive and Definitive Hematopoiesis.
data provide evidence that the oncogenicity of ERG is mediated, in part, by competition with ERF and they raise the larger question of whether other gain-of-function oncogenic transcription factors might also inactivate endogenous tumour suppressors
Title: ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis.
Oncogenic Ras may play a role in epithelial mesenchymal transition via the ERF and regulation of Semaphorin-7a.
Title: Semaphorin-7a reverses the ERF-induced inhibition of EMT in Ras-dependent mouse mammary epithelial cells.
Erf provides a direct link between the RAS/ERK signaling and the transcriptional regulation of c-Myc and suggests that RAS/ERK attenuation actively regulates cell fate
Title: The RAS-dependent ERF control of cell proliferation and differentiation is mediated by c-Myc repression.
These studies suggest "repressing repressors" as a potential strategy for achieving utrophin up-regulation in Duchenne's muscular dystrophy, and they provide a model for utrophin-A regulation in muscle.
Title: Ets-2 repressor factor silences extrasynaptic utrophin by N-box mediated repression in skeletal muscle.
The following Erf gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Erf cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu05646 | |
Clone ID Related Accession (Same CDS sequence) | NM_010155.3 | |
Accession Version | NM_010155.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1656bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-20 | |
Organism | Mus musculus(house mouse) | |
Product | ETS domain-containing transcription factor ERF | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC156992.13. On Apr 4, 2009 this sequence version replaced NM_010155.2. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC063092.1, AK159225.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849375, SAMN00849381 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAAGACCC CGGCGGACAC AGGGTTTGCC TTCCCAGATT GGGCCTACAA ACCGGAGTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_034285.3 |
CDS | 159..1814 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAAGACCC CGGCGGACAC AGGGTTTGCC TTCCCAGATT GGGCCTACAA ACCGGAGTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu89360 | |
Clone ID Related Accession (Same CDS sequence) | XM_030242130.1 , XM_030242129.1 | |
Accession Version | XM_030242130.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | ETS domain-containing transcription factor ERF isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACTATG ACAAGCTGAG CCGGGCTTTG CGCTATTATT ACAACAAGCG CATTCTACAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030097990.1 |
CDS | 348..1778 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAACTATG ACAAGCTGAG CCGGGCTTTG CGCTATTATT ACAACAAGCG CATTCTACAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu89360 | |
Clone ID Related Accession (Same CDS sequence) | XM_030242130.1 , XM_030242129.1 | |
Accession Version | XM_030242129.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1431bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | ETS domain-containing transcription factor ERF isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAACTATG ACAAGCTGAG CCGGGCTTTG CGCTATTATT ACAACAAGCG CATTCTACAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030097989.1 |
CDS | 276..1706 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGAACTATG ACAAGCTGAG CCGGGCTTTG CGCTATTATT ACAACAAGCG CATTCTACAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu89359 | |
Clone ID Related Accession (Same CDS sequence) | XM_030242128.1 | |
Accession Version | XM_030242128.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1659bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | ETS domain-containing transcription factor ERF isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTGTGTC CGATGAGGAA AGCCGGGTTT GCCTTCCCAG ATTGGGCCTA CAAACCGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030097988.1 |
CDS | 944..2602 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGCTGTGTC CGATGAGGAA AGCCGGGTTT GCCTTCCCAG ATTGGGCCTA CAAACCGGAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The Ets2 Repressor Factor (Erf) Is Required for Effective Primitive and Definitive Hematopoiesis. |
ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis. |
Early molecular events during retinoic acid induced differentiation of neuromesodermal progenitors. |
Articular cartilage endurance and resistance to osteoarthritic changes require transcription factor Erg. |