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Gabrb1 cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Gabrb1
Entrez Gene ID 14400
Full Name gamma-aminobutyric acid (GABA) A receptor, subunit beta 1
Synonyms AW061132,B230208N19Rik,Gabrb-1
General protein information
Preferred Names

gamma-aminobutyric acid (GABA) A receptor, subunit beta 1

Names

gamma-aminobutyric acid receptor subunit beta-1
GABA(A) receptor subunit beta-1
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

5

5 C3.2|5 38.18 cM

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_008069.5 NP_032095.1 gamma-aminobutyric acid receptor subunit beta-1 isoform 1 precursor
NM_001370968.1 NP_001357897.1 gamma-aminobutyric acid receptor subunit beta-1 isoform 2
NM_008069.4 NP_032095.1 gamma-aminobutyric acid receptor subunit beta-1 precursor
XM_006503736.3 XP_006503799.1 gamma-aminobutyric acid receptor subunit beta-1 isoform X1

Pathways from BioSystems


Homologies


GABRB1 XP_002804095.1
Canis lupus familiaris (dog) GABRB1 XP_005628215.1
Bos taurus (cattle) GABRB1 NP_776969.1
Mus musculus (house mouse) Gabrb1 NP_032095.1
Rattus norvegicus (Norway rat) Gabrb1 NP_037088.1
Xenopus tropicalis (tropical clawed frog) gabrb1 XP_004911268.1
Homo sapiens (human) GABRB1 NP_000803.2
Gallus gallus (chicken) GABRQ NP_001161175.1
Pan troglodytes (chimpanzee) GABRB1 XP_001154620.1
Danio rerio (zebrafish) gabrb1 XP_002664179.2

Gene Ontology


Bibliography

Related articles in PubMed

Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia.
Heng X, Guo Q, Leung AW, Li JY
eLife6(2017 May)

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.
Bedogni F, Cobolli Gigli C, Pozzi D, Rossi RL, Scaramuzza L, Rossetti G, Pagani M, Kilstrup-Nielsen C, Matteoli M, Landsberger N
Cerebral cortex (New York, N.Y. : 1991)26(6)2517-2529(2016 06)

Differential roles of GABAB1 subunit isoforms on locomotor responses to acute and repeated administration of cocaine.
Jacobson LH, Sweeney FF, Kaupmann K, O'Leary OF, Gassmann M, Bettler B, Cryan JF
Behavioural brain research298(Pt B)12-6(2016 Feb)

Early growth response 1 (Egr-1) directly regulates GABAA receptor ?2, ?4, and ? subunits in the hippocampus.
Mo J, Kim CH, Lee D, Sun W, Lee HW, Kim H
Journal of neurochemistry133(4)489-500(2015 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results indicate that GABAB1a and GABAB1b isoforms differentially regulate behavioural responses to cocaine, with deletion of GABAB1a enhancing cocaine-induced locomotor activity and deletion of GABAB1b protecting from cocaine-induced sensitisation
Title: Differential roles of GABAB1 subunit isoforms on locomotor responses to acute and repeated administration of cocaine.

Study of GABAB1 KO mice provides genetic evidence for a specific involvement of GABAB receptors in the regulation of the behavioral and biochemical effects induced by nicotine withdrawal in mice
Title: Lack of GABAB receptors modifies behavioural and biochemical alterations induced by precipitated nicotine withdrawal.

we conclude that is a greater contribution of beta(1) -subunit-containing GABA(A) receptors following oxygen and glucose deprivation in cerebellar Purkinje cells
Title: Alterations in Purkinje cell GABAA receptor pharmacology following oxygen and glucose deprivation and cerebral ischemia reveal novel contribution of ?1 -subunit-containing receptors.

Heritable preference for ethanol results from a dominant mutation L285R; P228H also causes high ethanol consumption
Title: Mutations in the Gabrb1 gene promote alcohol consumption through increased tonic inhibition.

GABA(B)R1 positively regulates chondrogenesis through a mechanism relevant to the acceleration of nuclear translocation of ATF4 for Ihh expression in chondrocytes
Title: Positive regulation by ?-aminobutyric acid B receptor subunit-1 of chondrogenesis through acceleration of nuclear translocation of activating transcription factor-4.

The following Gabrb1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gabrb1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu34942 NM_001370968.1
Latest version!		 Mus musculus gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 (Gabrb1), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
OMu34942 XM_006503736.3
Latest version!		 Mus musculus gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 (Gabrb1), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
OMu01317 NM_008069.5
Latest version!		 Mus musculus gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 (Gabrb1), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
View Old Accession Versions >>
OMu01317 NM_008069.4 Mus musculus gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 (Gabrb1), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $223.30
$319.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu34942
Clone ID Related Accession (Same CDS sequence) NM_001370968.1 , XM_006503736.3
Accession Version NM_001370968.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1326bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-09-29
Organism Mus musculus(house mouse)
Product gamma-aminobutyric acid receptor subunit beta-1 isoform 2
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC163437.16, AC114826.6, AC101688.13 and AC122915.2. On Jun 18, 2019 this sequence version replaced XM_006503736.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR6116558.71014.1, SRR7345562.3211076.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN01164131, SAMN01164132 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGTCATACG TGAAAGAGAC AGTGGACCGA CTGCTCAAAG GATATGACAT TCGCTTGCGG 
CCGGACTTTG GAGGGCCCCC GGTGGACGTC GGGATGCGGA TCGATGTCGC CAGCATAGAC 
ATGGTCTCGG AAGTGAATAT GGATTATACA CTCACCATGT ATTTCCAGCA GTCTTGGAAG 
GACAAGAGGC TTTCATATTC TGGAATCCCA TTAAATCTGA CCCTTGACAA CAGAGTAGCT 
GACCAACTCT GGGTACCAGA CACCTACTTT CTCAATGACA AGAAATCATT TGTGCATGGG 
GTCACAGTGA AAAACCGAAT GATCAGGCTG CATCCTGATG GAACTGTTCT CTATGGACTA 
CGGATCACAA CCACTGCAGC ATGCATGATG GATCTTCGAA GATACCCTCT GGATGAGCAA 
AACTGCACCC TGGAGATTGA AAGTTATGGC TATACCACGG ATGACATCGA ATTTTACTGG 
AATGGAGGAG AGGGAGCAGT AACTGGGGTC AATAAAATTG AGCTTCCCCA ATTTTCAATT 
GTTGACTACA AGATGGTGTC CAAGAAGGTG GAGTTCACAA CAGGGGCATA TCCACGACTA 
TCACTAAGTT TTCGTCTAAA GAGAAACATT GGTTACTTCA TTTTGCAGAC CTACATGCCT 
TCCACACTGA TTACAATCCT GTCCTGGGTG TCGTTTTGGA TCAACTATGA TGCATCTGCA 
GCCAGAGTCG CACTAGGAAT CACTACGGTG CTGACCATGA CCACCATCAG CACTCACCTC 
AGGGAGACTT TGCCGAAGAT CCCTTACGTC AAAGCGATTG ACATCTATCT CATGGGCTGT 
TTTGTGTTTG TGTTCCTGGC TCTACTGGAA TATGCTTTTG TCAATTACAT TTTCTTCGGA 
AAAGGCCCTC AGAAAAAGGG AGCGAGCAAA CAAGACCAGA GTGCCAATGA AAAGAACAGA 
CTGGAGATGA ACAAAGTCCA AGTTGATGCC CACGGCAATA TTCTCCTCAG CACCCTGGAA 
ATCAGGAACG AGACCAGTGG CTCCGAGGTG CTCACAGGTG TAAGTGACCC CAAGGCCACC 
ATGTACTCGT ACGACAGCGC CAGCATCCAG TACCGCAAGC CACTGAGCAG CCGCGAGGGC 
TTCGGGCGTG GGCTGGACAG GCACGGGGTA CCGGGCAAGG GGCGCATCCG CAGGCGCGCC 
TCGCAGCTCA AAGTGAAGAT CCCCGACTTG ACTGACGTGA ACTCCATAGA CAAGTGGTCC 
CGAATGTTCT TCCCCATCAC CTTTTCTCTT TTTAATGTCG TTTATTGGCT TTACTATGTA 
CACTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001357897.1
CDS313..1638
Translation

Target ORF information:

RefSeq Version NM_001370968.1
Organism Mus musculus(house mouse)
Definition Mus musculus gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 (Gabrb1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001370968.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGTCATACG TGAAAGAGAC AGTGGACCGA CTGCTCAAAG GATATGACAT TCGCTTGCGG 
CCGGACTTTG GAGGGCCCCC GGTGGACGTC GGGATGCGGA TCGATGTCGC CAGCATAGAC 
ATGGTCTCGG AAGTGAATAT GGATTATACA CTCACCATGT ATTTCCAGCA GTCTTGGAAG 
GACAAGAGGC TTTCATATTC TGGAATCCCA TTAAATCTGA CCCTTGACAA CAGAGTAGCT 
GACCAACTCT GGGTACCAGA CACCTACTTT CTCAATGACA AGAAATCATT TGTGCATGGG 
GTCACAGTGA AAAACCGAAT GATCAGGCTG CATCCTGATG GAACTGTTCT CTATGGACTA 
CGGATCACAA CCACTGCAGC ATGCATGATG GATCTTCGAA GATACCCTCT GGATGAGCAA 
AACTGCACCC TGGAGATTGA AAGTTATGGC TATACCACGG ATGACATCGA ATTTTACTGG 
AATGGAGGAG AGGGAGCAGT AACTGGGGTC AATAAAATTG AGCTTCCCCA ATTTTCAATT 
GTTGACTACA AGATGGTGTC CAAGAAGGTG GAGTTCACAA CAGGGGCATA TCCACGACTA 
TCACTAAGTT TTCGTCTAAA GAGAAACATT GGTTACTTCA TTTTGCAGAC CTACATGCCT 
TCCACACTGA TTACAATCCT GTCCTGGGTG TCGTTTTGGA TCAACTATGA TGCATCTGCA 
GCCAGAGTCG CACTAGGAAT CACTACGGTG CTGACCATGA CCACCATCAG CACTCACCTC 
AGGGAGACTT TGCCGAAGAT CCCTTACGTC AAAGCGATTG ACATCTATCT CATGGGCTGT 
TTTGTGTTTG TGTTCCTGGC TCTACTGGAA TATGCTTTTG TCAATTACAT TTTCTTCGGA 
AAAGGCCCTC AGAAAAAGGG AGCGAGCAAA CAAGACCAGA GTGCCAATGA AAAGAACAGA 
CTGGAGATGA ACAAAGTCCA AGTTGATGCC CACGGCAATA TTCTCCTCAG CACCCTGGAA 
ATCAGGAACG AGACCAGTGG CTCCGAGGTG CTCACAGGTG TAAGTGACCC CAAGGCCACC 
ATGTACTCGT ACGACAGCGC CAGCATCCAG TACCGCAAGC CACTGAGCAG CCGCGAGGGC 
TTCGGGCGTG GGCTGGACAG GCACGGGGTA CCGGGCAAGG GGCGCATCCG CAGGCGCGCC 
TCGCAGCTCA AAGTGAAGAT CCCCGACTTG ACTGACGTGA ACTCCATAGA CAAGTGGTCC 
CGAATGTTCT TCCCCATCAC CTTTTCTCTT TTTAATGTCG TTTATTGGCT TTACTATGTA 
CACTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu34942
Clone ID Related Accession (Same CDS sequence) NM_001370968.1 , XM_006503736.3
Accession Version XM_006503736.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1326bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product gamma-aminobutyric acid receptor subunit beta-1 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000071.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006503736.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGTCATACG TGAAAGAGAC AGTGGACCGA CTGCTCAAAG GATATGACAT TCGCTTGCGG 
CCGGACTTTG GAGGGCCCCC GGTGGACGTC GGGATGCGGA TCGATGTCGC CAGCATAGAC 
ATGGTCTCGG AAGTGAATAT GGATTATACA CTCACCATGT ATTTCCAGCA GTCTTGGAAG 
GACAAGAGGC TTTCATATTC TGGAATCCCA TTAAATCTGA CCCTTGACAA CAGAGTAGCT 
GACCAACTCT GGGTACCAGA CACCTACTTT CTCAATGACA AGAAATCATT TGTGCATGGG 
GTCACAGTGA AAAACCGAAT GATCAGGCTG CATCCTGATG GAACTGTTCT CTATGGACTA 
CGGATCACAA CCACTGCAGC ATGCATGATG GATCTTCGAA GATACCCTCT GGATGAGCAA 
AACTGCACCC TGGAGATTGA AAGTTATGGC TATACCACGG ATGACATCGA ATTTTACTGG 
AATGGAGGAG AGGGAGCAGT AACTGGGGTC AATAAAATTG AGCTTCCCCA ATTTTCAATT 
GTTGACTACA AGATGGTGTC CAAGAAGGTG GAGTTCACAA CAGGGGCATA TCCACGACTA 
TCACTAAGTT TTCGTCTAAA GAGAAACATT GGTTACTTCA TTTTGCAGAC CTACATGCCT 
TCCACACTGA TTACAATCCT GTCCTGGGTG TCGTTTTGGA TCAACTATGA TGCATCTGCA 
GCCAGAGTCG CACTAGGAAT CACTACGGTG CTGACCATGA CCACCATCAG CACTCACCTC 
AGGGAGACTT TGCCGAAGAT CCCTTACGTC AAAGCGATTG ACATCTATCT CATGGGCTGT 
TTTGTGTTTG TGTTCCTGGC TCTACTGGAA TATGCTTTTG TCAATTACAT TTTCTTCGGA 
AAAGGCCCTC AGAAAAAGGG AGCGAGCAAA CAAGACCAGA GTGCCAATGA AAAGAACAGA 
CTGGAGATGA ACAAAGTCCA AGTTGATGCC CACGGCAATA TTCTCCTCAG CACCCTGGAA 
ATCAGGAACG AGACCAGTGG CTCCGAGGTG CTCACAGGTG TAAGTGACCC CAAGGCCACC 
ATGTACTCGT ACGACAGCGC CAGCATCCAG TACCGCAAGC CACTGAGCAG CCGCGAGGGC 
TTCGGGCGTG GGCTGGACAG GCACGGGGTA CCGGGCAAGG GGCGCATCCG CAGGCGCGCC 
TCGCAGCTCA AAGTGAAGAT CCCCGACTTG ACTGACGTGA ACTCCATAGA CAAGTGGTCC 
CGAATGTTCT TCCCCATCAC CTTTTCTCTT TTTAATGTCG TTTATTGGCT TTACTATGTA 
CACTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006503799.1
CDS180..1505
Translation

Target ORF information:

RefSeq Version XM_006503736.3
Organism Mus musculus(house mouse)
Definition Mus musculus gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 (Gabrb1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006503736.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
ATGTCATACG TGAAAGAGAC AGTGGACCGA CTGCTCAAAG GATATGACAT TCGCTTGCGG 
CCGGACTTTG GAGGGCCCCC GGTGGACGTC GGGATGCGGA TCGATGTCGC CAGCATAGAC 
ATGGTCTCGG AAGTGAATAT GGATTATACA CTCACCATGT ATTTCCAGCA GTCTTGGAAG 
GACAAGAGGC TTTCATATTC TGGAATCCCA TTAAATCTGA CCCTTGACAA CAGAGTAGCT 
GACCAACTCT GGGTACCAGA CACCTACTTT CTCAATGACA AGAAATCATT TGTGCATGGG 
GTCACAGTGA AAAACCGAAT GATCAGGCTG CATCCTGATG GAACTGTTCT CTATGGACTA 
CGGATCACAA CCACTGCAGC ATGCATGATG GATCTTCGAA GATACCCTCT GGATGAGCAA 
AACTGCACCC TGGAGATTGA AAGTTATGGC TATACCACGG ATGACATCGA ATTTTACTGG 
AATGGAGGAG AGGGAGCAGT AACTGGGGTC AATAAAATTG AGCTTCCCCA ATTTTCAATT 
GTTGACTACA AGATGGTGTC CAAGAAGGTG GAGTTCACAA CAGGGGCATA TCCACGACTA 
TCACTAAGTT TTCGTCTAAA GAGAAACATT GGTTACTTCA TTTTGCAGAC CTACATGCCT 
TCCACACTGA TTACAATCCT GTCCTGGGTG TCGTTTTGGA TCAACTATGA TGCATCTGCA 
GCCAGAGTCG CACTAGGAAT CACTACGGTG CTGACCATGA CCACCATCAG CACTCACCTC 
AGGGAGACTT TGCCGAAGAT CCCTTACGTC AAAGCGATTG ACATCTATCT CATGGGCTGT 
TTTGTGTTTG TGTTCCTGGC TCTACTGGAA TATGCTTTTG TCAATTACAT TTTCTTCGGA 
AAAGGCCCTC AGAAAAAGGG AGCGAGCAAA CAAGACCAGA GTGCCAATGA AAAGAACAGA 
CTGGAGATGA ACAAAGTCCA AGTTGATGCC CACGGCAATA TTCTCCTCAG CACCCTGGAA 
ATCAGGAACG AGACCAGTGG CTCCGAGGTG CTCACAGGTG TAAGTGACCC CAAGGCCACC 
ATGTACTCGT ACGACAGCGC CAGCATCCAG TACCGCAAGC CACTGAGCAG CCGCGAGGGC 
TTCGGGCGTG GGCTGGACAG GCACGGGGTA CCGGGCAAGG GGCGCATCCG CAGGCGCGCC 
TCGCAGCTCA AAGTGAAGAT CCCCGACTTG ACTGACGTGA ACTCCATAGA CAAGTGGTCC 
CGAATGTTCT TCCCCATCAC CTTTTCTCTT TTTAATGTCG TTTATTGGCT TTACTATGTA 
CACTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu01317
Clone ID Related Accession (Same CDS sequence) NM_008069.5 , NM_008069.4
Accession Version NM_008069.5 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1425bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Mus musculus(house mouse)
Product gamma-aminobutyric acid receptor subunit beta-1 isoform 1 precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC114826.6, AC101688.13 and AC122915.2. On Jun 18, 2019 this sequence version replaced NM_008069.4. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC157920.1, SRR1660817.251971.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGTGGACAG TACAAAATCG AGAGAGTTTG GGGCTTCTCT CTTTTCCCGT GATGGTTGCT 
ATGGTTTGTT GTGCACACAG CTCCAATGAA CCCAGCAACA TGTCATACGT GAAAGAGACA 
GTGGACCGAC TGCTCAAAGG ATATGACATT CGCTTGCGGC CGGACTTTGG AGGGCCCCCG 
GTGGACGTCG GGATGCGGAT CGATGTCGCC AGCATAGACA TGGTCTCGGA AGTGAATATG 
GATTATACAC TCACCATGTA TTTCCAGCAG TCTTGGAAGG ACAAGAGGCT TTCATATTCT 
GGAATCCCAT TAAATCTGAC CCTTGACAAC AGAGTAGCTG ACCAACTCTG GGTACCAGAC 
ACCTACTTTC TCAATGACAA GAAATCATTT GTGCATGGGG TCACAGTGAA AAACCGAATG 
ATCAGGCTGC ATCCTGATGG AACTGTTCTC TATGGACTAC GGATCACAAC CACTGCAGCA 
TGCATGATGG ATCTTCGAAG ATACCCTCTG GATGAGCAAA ACTGCACCCT GGAGATTGAA 
AGTTATGGCT ATACCACGGA TGACATCGAA TTTTACTGGA ATGGAGGAGA GGGAGCAGTA 
ACTGGGGTCA ATAAAATTGA GCTTCCCCAA TTTTCAATTG TTGACTACAA GATGGTGTCC 
AAGAAGGTGG AGTTCACAAC AGGGGCATAT CCACGACTAT CACTAAGTTT TCGTCTAAAG 
AGAAACATTG GTTACTTCAT TTTGCAGACC TACATGCCTT CCACACTGAT TACAATCCTG 
TCCTGGGTGT CGTTTTGGAT CAACTATGAT GCATCTGCAG CCAGAGTCGC ACTAGGAATC 
ACTACGGTGC TGACCATGAC CACCATCAGC ACTCACCTCA GGGAGACTTT GCCGAAGATC 
CCTTACGTCA AAGCGATTGA CATCTATCTC ATGGGCTGTT TTGTGTTTGT GTTCCTGGCT 
CTACTGGAAT ATGCTTTTGT CAATTACATT TTCTTCGGAA AAGGCCCTCA GAAAAAGGGA 
GCGAGCAAAC AAGACCAGAG TGCCAATGAA AAGAACAGAC TGGAGATGAA CAAAGTCCAA 
GTTGATGCCC ACGGCAATAT TCTCCTCAGC ACCCTGGAAA TCAGGAACGA GACCAGTGGC 
TCCGAGGTGC TCACAGGTGT AAGTGACCCC AAGGCCACCA TGTACTCGTA CGACAGCGCC 
AGCATCCAGT ACCGCAAGCC ACTGAGCAGC CGCGAGGGCT TCGGGCGTGG GCTGGACAGG 
CACGGGGTAC CGGGCAAGGG GCGCATCCGC AGGCGCGCCT CGCAGCTCAA AGTGAAGATC 
CCCGACTTGA CTGACGTGAA CTCCATAGAC AAGTGGTCCC GAATGTTCTT CCCCATCACC 
TTTTCTCTTT TTAATGTCGT TTATTGGCTT TACTATGTAC ACTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_032095.1
CDS85..1509
Translation

Target ORF information:

RefSeq Version NM_008069.5
Organism Mus musculus(house mouse)
Definition Mus musculus gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 (Gabrb1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_008069.5

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGTGGACAG TACAAAATCG AGAGAGTTTG GGGCTTCTCT CTTTTCCCGT GATGGTTGCT 
ATGGTTTGTT GTGCACACAG CTCCAATGAA CCCAGCAACA TGTCATACGT GAAAGAGACA 
GTGGACCGAC TGCTCAAAGG ATATGACATT CGCTTGCGGC CGGACTTTGG AGGGCCCCCG 
GTGGACGTCG GGATGCGGAT CGATGTCGCC AGCATAGACA TGGTCTCGGA AGTGAATATG 
GATTATACAC TCACCATGTA TTTCCAGCAG TCTTGGAAGG ACAAGAGGCT TTCATATTCT 
GGAATCCCAT TAAATCTGAC CCTTGACAAC AGAGTAGCTG ACCAACTCTG GGTACCAGAC 
ACCTACTTTC TCAATGACAA GAAATCATTT GTGCATGGGG TCACAGTGAA AAACCGAATG 
ATCAGGCTGC ATCCTGATGG AACTGTTCTC TATGGACTAC GGATCACAAC CACTGCAGCA 
TGCATGATGG ATCTTCGAAG ATACCCTCTG GATGAGCAAA ACTGCACCCT GGAGATTGAA 
AGTTATGGCT ATACCACGGA TGACATCGAA TTTTACTGGA ATGGAGGAGA GGGAGCAGTA 
ACTGGGGTCA ATAAAATTGA GCTTCCCCAA TTTTCAATTG TTGACTACAA GATGGTGTCC 
AAGAAGGTGG AGTTCACAAC AGGGGCATAT CCACGACTAT CACTAAGTTT TCGTCTAAAG 
AGAAACATTG GTTACTTCAT TTTGCAGACC TACATGCCTT CCACACTGAT TACAATCCTG 
TCCTGGGTGT CGTTTTGGAT CAACTATGAT GCATCTGCAG CCAGAGTCGC ACTAGGAATC 
ACTACGGTGC TGACCATGAC CACCATCAGC ACTCACCTCA GGGAGACTTT GCCGAAGATC 
CCTTACGTCA AAGCGATTGA CATCTATCTC ATGGGCTGTT TTGTGTTTGT GTTCCTGGCT 
CTACTGGAAT ATGCTTTTGT CAATTACATT TTCTTCGGAA AAGGCCCTCA GAAAAAGGGA 
GCGAGCAAAC AAGACCAGAG TGCCAATGAA AAGAACAGAC TGGAGATGAA CAAAGTCCAA 
GTTGATGCCC ACGGCAATAT TCTCCTCAGC ACCCTGGAAA TCAGGAACGA GACCAGTGGC 
TCCGAGGTGC TCACAGGTGT AAGTGACCCC AAGGCCACCA TGTACTCGTA CGACAGCGCC 
AGCATCCAGT ACCGCAAGCC ACTGAGCAGC CGCGAGGGCT TCGGGCGTGG GCTGGACAGG 
CACGGGGTAC CGGGCAAGGG GCGCATCCGC AGGCGCGCCT CGCAGCTCAA AGTGAAGATC 
CCCGACTTGA CTGACGTGAA CTCCATAGAC AAGTGGTCCC GAATGTTCTT CCCCATCACC 
TTTTCTCTTT TTAATGTCGT TTATTGGCTT TACTATGTAC ACTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu01317
Clone ID Related Accession (Same CDS sequence) NM_008069.5 , NM_008069.4
Accession Version NM_008069.4 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 1425bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-02-22
Organism Mus musculus(house mouse)
Product gamma-aminobutyric acid receptor subunit beta-1 precursor
Comment Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC114826.6, AC101688.13 and AC122915.2. On Nov 17, 2006 this sequence version replaced NM_008069.3. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC157920.1, SRR1660815.88754.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN01164131 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGTGGACAG TACAAAATCG AGAGAGTTTG GGGCTTCTCT CTTTTCCCGT GATGGTTGCT 
ATGGTTTGTT GTGCACACAG CTCCAATGAA CCCAGCAACA TGTCATACGT GAAAGAGACA 
GTGGACCGAC TGCTCAAAGG ATATGACATT CGCTTGCGGC CGGACTTTGG AGGGCCCCCG 
GTGGACGTCG GGATGCGGAT CGATGTCGCC AGCATAGACA TGGTCTCGGA AGTGAATATG 
GATTATACAC TCACCATGTA TTTCCAGCAG TCTTGGAAGG ACAAGAGGCT TTCATATTCT 
GGAATCCCAT TAAATCTGAC CCTTGACAAC AGAGTAGCTG ACCAACTCTG GGTACCAGAC 
ACCTACTTTC TCAATGACAA GAAATCATTT GTGCATGGGG TCACAGTGAA AAACCGAATG 
ATCAGGCTGC ATCCTGATGG AACTGTTCTC TATGGACTAC GGATCACAAC CACTGCAGCA 
TGCATGATGG ATCTTCGAAG ATACCCTCTG GATGAGCAAA ACTGCACCCT GGAGATTGAA 
AGTTATGGCT ATACCACGGA TGACATCGAA TTTTACTGGA ATGGAGGAGA GGGAGCAGTA 
ACTGGGGTCA ATAAAATTGA GCTTCCCCAA TTTTCAATTG TTGACTACAA GATGGTGTCC 
AAGAAGGTGG AGTTCACAAC AGGGGCATAT CCACGACTAT CACTAAGTTT TCGTCTAAAG 
AGAAACATTG GTTACTTCAT TTTGCAGACC TACATGCCTT CCACACTGAT TACAATCCTG 
TCCTGGGTGT CGTTTTGGAT CAACTATGAT GCATCTGCAG CCAGAGTCGC ACTAGGAATC 
ACTACGGTGC TGACCATGAC CACCATCAGC ACTCACCTCA GGGAGACTTT GCCGAAGATC 
CCTTACGTCA AAGCGATTGA CATCTATCTC ATGGGCTGTT TTGTGTTTGT GTTCCTGGCT 
CTACTGGAAT ATGCTTTTGT CAATTACATT TTCTTCGGAA AAGGCCCTCA GAAAAAGGGA 
GCGAGCAAAC AAGACCAGAG TGCCAATGAA AAGAACAGAC TGGAGATGAA CAAAGTCCAA 
GTTGATGCCC ACGGCAATAT TCTCCTCAGC ACCCTGGAAA TCAGGAACGA GACCAGTGGC 
TCCGAGGTGC TCACAGGTGT AAGTGACCCC AAGGCCACCA TGTACTCGTA CGACAGCGCC 
AGCATCCAGT ACCGCAAGCC ACTGAGCAGC CGCGAGGGCT TCGGGCGTGG GCTGGACAGG 
CACGGGGTAC CGGGCAAGGG GCGCATCCGC AGGCGCGCCT CGCAGCTCAA AGTGAAGATC 
CCCGACTTGA CTGACGTGAA CTCCATAGAC AAGTGGTCCC GAATGTTCTT CCCCATCACC 
TTTTCTCTTT TTAATGTCGT TTATTGGCTT TACTATGTAC ACTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_032095.1
CDS1..1425
Translation

Target ORF information:

RefSeq Version NM_008069.4
Organism Mus musculus(house mouse)
Definition Mus musculus gamma-aminobutyric acid (GABA) A receptor, subunit beta 1 (Gabrb1), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_008069.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
601
661
721
781
841
901
961
1021
1081
1141
1201
1261
1321
1381
ATGTGGACAG TACAAAATCG AGAGAGTTTG GGGCTTCTCT CTTTTCCCGT GATGGTTGCT 
ATGGTTTGTT GTGCACACAG CTCCAATGAA CCCAGCAACA TGTCATACGT GAAAGAGACA 
GTGGACCGAC TGCTCAAAGG ATATGACATT CGCTTGCGGC CGGACTTTGG AGGGCCCCCG 
GTGGACGTCG GGATGCGGAT CGATGTCGCC AGCATAGACA TGGTCTCGGA AGTGAATATG 
GATTATACAC TCACCATGTA TTTCCAGCAG TCTTGGAAGG ACAAGAGGCT TTCATATTCT 
GGAATCCCAT TAAATCTGAC CCTTGACAAC AGAGTAGCTG ACCAACTCTG GGTACCAGAC 
ACCTACTTTC TCAATGACAA GAAATCATTT GTGCATGGGG TCACAGTGAA AAACCGAATG 
ATCAGGCTGC ATCCTGATGG AACTGTTCTC TATGGACTAC GGATCACAAC CACTGCAGCA 
TGCATGATGG ATCTTCGAAG ATACCCTCTG GATGAGCAAA ACTGCACCCT GGAGATTGAA 
AGTTATGGCT ATACCACGGA TGACATCGAA TTTTACTGGA ATGGAGGAGA GGGAGCAGTA 
ACTGGGGTCA ATAAAATTGA GCTTCCCCAA TTTTCAATTG TTGACTACAA GATGGTGTCC 
AAGAAGGTGG AGTTCACAAC AGGGGCATAT CCACGACTAT CACTAAGTTT TCGTCTAAAG 
AGAAACATTG GTTACTTCAT TTTGCAGACC TACATGCCTT CCACACTGAT TACAATCCTG 
TCCTGGGTGT CGTTTTGGAT CAACTATGAT GCATCTGCAG CCAGAGTCGC ACTAGGAATC 
ACTACGGTGC TGACCATGAC CACCATCAGC ACTCACCTCA GGGAGACTTT GCCGAAGATC 
CCTTACGTCA AAGCGATTGA CATCTATCTC ATGGGCTGTT TTGTGTTTGT GTTCCTGGCT 
CTACTGGAAT ATGCTTTTGT CAATTACATT TTCTTCGGAA AAGGCCCTCA GAAAAAGGGA 
GCGAGCAAAC AAGACCAGAG TGCCAATGAA AAGAACAGAC TGGAGATGAA CAAAGTCCAA 
GTTGATGCCC ACGGCAATAT TCTCCTCAGC ACCCTGGAAA TCAGGAACGA GACCAGTGGC 
TCCGAGGTGC TCACAGGTGT AAGTGACCCC AAGGCCACCA TGTACTCGTA CGACAGCGCC 
AGCATCCAGT ACCGCAAGCC ACTGAGCAGC CGCGAGGGCT TCGGGCGTGG GCTGGACAGG 
CACGGGGTAC CGGGCAAGGG GCGCATCCGC AGGCGCGCCT CGCAGCTCAA AGTGAAGATC 
CCCGACTTGA CTGACGTGAA CTCCATAGAC AAGTGGTCCC GAATGTTCTT CCCCATCACC 
TTTTCTCTTT TTAATGTCGT TTATTGGCTT TACTATGTAC ACTAA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Analogous mechanism regulating formation of neocortical basal radial glia and cerebellar Bergmann glia.
eLife6(2017 May)
Heng X,Guo Q,Leung AW,Li JY


book

Defects During Mecp2 Null Embryonic Cortex Development Precede the Onset of Overt Neurological Symptoms.
Cerebral cortex (New York, N.Y. : 1991)26(6)2517-2529(2016 06)
Bedogni F,Cobolli Gigli C,Pozzi D,Rossi RL,Scaramuzza L,Rossetti G,Pagani M,Kilstrup-Nielsen C,Matteoli M,Landsberger N


book

Differential roles of GABAB1 subunit isoforms on locomotor responses to acute and repeated administration of cocaine.
Behavioural brain research298(Pt B)12-6(2016 Feb)
Jacobson LH,Sweeney FF,Kaupmann K,O'Leary OF,Gassmann M,Bettler B,Cryan JF


book

Early growth response 1 (Egr-1) directly regulates GABAA receptor ?2, ?4, and ? subunits in the hippocampus.
Journal of neurochemistry133(4)489-500(2015 May)
Mo J,Kim CH,Lee D,Sun W,Lee HW,Kim H