Gm2a cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | Gm2a |
| Entrez Gene ID | 14667 |
| Full Name | GM2 ganglioside activator protein |
| Synonyms | AA408702,AW215435,GM2-AP,SAP-3 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_010299.3 | NP_034429.1 | ganglioside GM2 activator precursor |
| LOC713375 | XP_001109570.1 | |
| Canis lupus familiaris (dog) | GM2A | XP_003639059.1 |
| Homo sapiens (human) | GM2A | NP_000396.2 |
| Pan troglodytes (chimpanzee) | GM2A | XP_003950707.1 |
| Bos taurus (cattle) | GM2A | NP_001192476.1 |
| Gallus gallus (chicken) | GM2A | XP_003642107.2 |
| Xenopus tropicalis (tropical clawed frog) | gm2a | NP_001017081.1 |
| Xenopus tropicalis (tropical clawed frog) | LOC100495195 | XP_002932357.2 |
| Mus musculus (house mouse) | Gm2a | NP_034429.1 |
| Rattus norvegicus (Norway rat) | Gm2a | NP_758838.2 |
| Danio rerio (zebrafish) | gm2a | NP_001017831.1 |
Related articles in PubMed
Expression of the GM2 activator protein in mouse testis.
Li YT, Li SC, Chen IL
Reproductive biology17(4)376-379(2017 Dec)
Transcription Factor MafB Coordinates Epidermal Keratinocyte Differentiation.
Miyai M, Hamada M, Moriguchi T, Hiruma J, Kamitani-Kawamoto A, Watanabe H, Hara-Chikuma M, Takahashi K, Takahashi S, Kataoka K
The Journal of investigative dermatology136(9)1848-57(2016 Sep)
Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network.
Shalom-Barak T, Zhang X, Chu T, Timothy Schaiff W, Reddy JK, Xu J, Sadovsky Y, Barak Y
Developmental biology372(1)143-55(2012 Dec)
Adipokine ganglioside GM2 activator protein stimulates insulin secretion.
Higashi K, Kubo H, Watanabe H, Fujimori K, Mikami T, Kaneko H
FEBS letters585(16)2587-91(2011 Aug)
A novel adipokine GM2AP impairs insulin signaling.
Higashi K, Mikami T, Yamada T, Kawashima H, Kimura T, Kaneko H
Biochemical and biophysical research communications402(3)571-6(2010 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
impact of GM2AP on glucose metabolism
Title: Adipokine ganglioside GM2 activator protein stimulates insulin secretion.
these results provide novel insights into the physiological functions of GM2AP in obesity.
Title: A novel adipokine GM2AP impairs insulin signaling.
The trafficking of prosaposin and GM2 activator protein to the lysosome in sertoli cells is dependent on sortilin.
Title: The trafficking of prosaposin (SGP-1) and GM2AP to the lysosomes of TM4 Sertoli cells is mediated by sortilin and monomeric adaptor proteins.
GM2 activator protein exerts strong and broad inhibitory effects on the hydrolysis of phospholipids carried out by plant and microbial phospholipases D
Title: Effect of GM2 activator protein on the enzymatic hydrolysis of phospholipids and sphingomyelin.
The following Gm2a gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Gm2a cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu05911 | |
| Clone ID Related Accession (Same CDS sequence) | NM_010299.3 | |
| Accession Version | NM_010299.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 582bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-18 | |
| Organism | Mus musculus(house mouse) | |
| Product | ganglioside GM2 activator precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BB856051.1, BC004651.1 and AL772357.9. On Apr 21, 2011 this sequence version replaced NM_010299.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1660813.228571.1, AK149642.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGCACCGTC TACCGCTGCT GCTCCTGCTG GGCTTGCTGC TCGCAGGCTC CGTCGCCCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_034429.1 |
| CDS | 180..761 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_010299.3 |
ORF Insert Sequence:
1 | ATGCACCGTC TACCGCTGCT GCTCCTGCTG GGCTTGCTGC TCGCAGGCTC CGTCGCCCCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Expression of the GM2 activator protein in mouse testis. |
|
Transcription Factor MafB Coordinates Epidermal Keratinocyte Differentiation. |
|
Placental PPARγ regulates spatiotemporally diverse genes and a unique metabolic network. |
|
Adipokine ganglioside GM2 activator protein stimulates insulin secretion. |
|
A novel adipokine GM2AP impairs insulin signaling. |