Gene Symbol | Mcpt8 |
Entrez Gene ID | 17231 |
Full Name | mast cell protease 8 |
Synonyms | BB139338,MMCP-8 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Mcpt8 cDNA ORF clone
gRNAs
Gene Symbol | Mcpt8 |
Entrez Gene ID | 17231 |
Full Name | mast cell protease 8 |
Synonyms | BB139338,MMCP-8 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006518671.3 | XP_006518734.1 | mast cell protease 8 isoform X1 |
NM_008572.1 | NP_032598.1 | mast cell protease 8 precursor |
Treatment of MCPT8
Hachem CE, Hener P, Kirstetter P, Li J, Chan S, Li M
European journal of immunology(2018 Jan)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
These results suggest that mMCP-8 is an important effector molecule in basophil-elicited inflammation, providing novel insights into how basophils exert a crucial and non-redundant role, distinct from that played by mast cells, in immune responses.
Title: The Basophil-specific Protease mMCP-8 Provokes an Inflammatory Response in the Skin with Microvascular Hyperpermeability and Leukocyte Infiltration.
The proteolytic activity of mMCP-8 as a first representative for the Mcpt8-subfamilywas studied.
Title: Expression profile of novel members of the rat mast cell protease (rMCP)-2 and (rMCP)-8 families, and functional analyses of mouse mast cell protease (mMCP)-8.
The following Mcpt8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mcpt8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu49757 | |
Clone ID Related Accession (Same CDS sequence) | XM_006518671.3 | |
Accession Version | XM_006518671.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 420bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | mast cell protease 8 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006518671.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGCTCCTGA AGCTGGAACG CAAAGCTCAA CTCAACAGTG CTGTGGATAC TATTGCCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006518734.1 |
CDS | 489..908 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGCTCCTGA AGCTGGAACG CAAAGCTCAA CTCAACAGTG CTGTGGATAC TATTGCCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu22331 | |
Clone ID Related Accession (Same CDS sequence) | NM_008572.1 | |
Accession Version | NM_008572.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 744bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Mus musculus(house mouse) | |
Product | mast cell protease 8 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X78545.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: X78545.1, AK136485.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849381, SAMN00849388 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGTTCCTGC TCCTGGTCCT CCTGGTGGCT GCCCTGCCAG TCAACGCTGA AGGAGGGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_032598.1 |
CDS | 11..754 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTTCCTGC TCCTGGTCCT CCTGGTGGCT GCCCTGCCAG TCAACGCTGA AGGAGGGGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Treatment of MCPT8 |