Il20rb cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | Il20rb |
| Entrez Gene ID | 213208 |
| Full Name | interleukin 20 receptor beta |
| Synonyms | AV228068,Fndc6,Gm186,Il20R2 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_001033543.3 | NP_001028715.2 | interleukin-20 receptor subunit beta precursor |
| Pan troglodytes (chimpanzee) | IL20RB | XP_001154958.1 |
| Bos taurus (cattle) | IL20RB | NP_001095645.1 |
| Rattus norvegicus (Norway rat) | Il20rb | NP_001166909.1 |
| Xenopus tropicalis (tropical clawed frog) | il20rb | XP_004917829.1 |
| Homo sapiens (human) | IL20RB | NP_653318.2 |
| Mus musculus (house mouse) | Il20rb | NP_001028715.2 |
| Gallus gallus (chicken) | IL20RB | XP_001231360.2 |
| IL20RB | XP_001114770.1 | |
| Canis lupus familiaris (dog) | IL20RB | XP_005634529.1 |
Related articles in PubMed
Alternative splicing directs two IL-20R2 isoforms and is responsible for the incomplete gene knockout via the exon I ablation.
Zhou H, Liu X, Yu R, Long T, Zhao R, Liu H, Xu Y, Liang JG, Liang P
Genes and immunity17(4)220-7(2016 06)
Signaling via the IL-20 receptor inhibits cutaneous production of IL-1? and IL-17A to promote infection with methicillin-resistant Staphylococcus aureus.
Myles IA, Fontecilla NM, Valdez PA, Vithayathil PJ, Naik S, Belkaid Y, Ouyang W, Datta SK
Nature immunology14(8)804-11(2013 Aug)
Detection of IL-20R1 and IL-20R2 mRNA in C57BL/6 mice astroglial cells and brain cortex following LPS stimulation.
Abd Nikfarjam B, Ebtekar M, Sabouni F, Pourpak Z, Kheirandish M
Iranian journal of immunology : IJI10(2)62-9(2013 Jun)
Anti-IL-20 monoclonal antibody inhibits the differentiation of osteoclasts and protects against osteoporotic bone loss.
Hsu YH, Chen WY, Chan CH, Wu CH, Sun ZJ, Chang MS
The Journal of experimental medicine208(9)1849-61(2011 Aug)
PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression.
Kirchhof P, Kahr PC, Kaese S, Piccini I, Vokshi I, Scheld HH, Rotering H, Fortmueller L, Laakmann S, Verheule S, Schotten U, Fabritz L, Brown NA
Circulation. Cardiovascular genetics4(2)123-33(2011 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
IL-20R1 and IL-20R2 are constitutively express in the brain.
Title: Detection of IL-20R1 and IL-20R2 mRNA in C57BL/6 mice astroglial cells and brain cortex following LPS stimulation.
IL-20R2 regulates T cell activation directly and attenuates antigen-specific CD8 responses; IL-20R2 signaling directly regulates CD8 and CD4 T cell responses in vitro and in vivo.
Title: IL-20 receptor 2 signaling down-regulates antigen-specific T cell responses.
IL-20R2 receptor subunit is up-regulated by LPS in the liver of normal mice.
Title: The murine liver is a potential target organ for IL-19, IL-20 and IL-24: Type I Interferons and LPS regulate the expression of IL-20R2.
The following Il20rb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Il20rb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu15118 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001033543.3 | |
| Accession Version | NM_001033543.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 927bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-09-09 | |
| Organism | Mus musculus(house mouse) | |
| Product | interleukin-20 receptor subunit beta precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BY772000.1, CK331954.1, AC134590.5 and BE852308.1. On Oct 18, 2007 this sequence version replaced NM_001033543.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data because no single transcript from the same strain was available for the full length of the gene. The extent of this transcript is supported by transcript alignments and orthologous data. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGATTTCCC AGGGAGTCTG GACAAGTCCG TTCATGTGGT TTTTCTACAG CATGACCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001028715.2 |
| CDS | 146..1072 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001033543.3 |
ORF Insert Sequence:
1 | ATGATTTCCC AGGGAGTCTG GACAAGTCCG TTCATGTGGT TTTTCTACAG CATGACCTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
Alternative splicing directs two IL-20R2 isoforms and is responsible for the incomplete gene knockout via the exon I ablation. |
|
Signaling via the IL-20 receptor inhibits cutaneous production of IL-1? and IL-17A to promote infection with methicillin-resistant Staphylococcus aureus. |
|
Detection of IL-20R1 and IL-20R2 mRNA in C57BL/6 mice astroglial cells and brain cortex following LPS stimulation. |
|
Anti-IL-20 monoclonal antibody inhibits the differentiation of osteoclasts and protects against osteoporotic bone loss. |
|
PITX2c is expressed in the adult left atrium, and reducing Pitx2c expression promotes atrial fibrillation inducibility and complex changes in gene expression. |