Gene Symbol | Cnksr3 |
Entrez Gene ID | 215748 |
Full Name | Cnksr family member 3 |
Synonyms | 6820402C05,BC024086,Magi1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Cnksr3 cDNA ORF clone
Gene Symbol | Cnksr3 |
Entrez Gene ID | 215748 |
Full Name | Cnksr family member 3 |
Synonyms | 6820402C05,BC024086,Magi1 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_030244998.1 | XP_030100858.1 | connector enhancer of kinase suppressor of ras 3 isoform X1 |
XM_011243079.1 | XP_011241381.1 | connector enhancer of kinase suppressor of ras 3 isoform X1 |
NM_172546.2 | NP_766134.1 | connector enhancer of kinase suppressor of ras 3 |
Homo sapiens (human) | CNKSR3 | NP_775786.2 |
Bos taurus (cattle) | CNKSR3 | NP_001179041.1 |
CNKSR3 | XP_001095122.1 | |
Canis lupus familiaris (dog) | IPCEF1 | XP_005615587.1 |
Pan troglodytes (chimpanzee) | CNKSR3 | XP_518820.3 |
Xenopus tropicalis (tropical clawed frog) | cnksr3 | NP_001135662.1 |
Rattus norvegicus (Norway rat) | Cnksr3 | NP_001012061.1 |
Gallus gallus (chicken) | CNKSR3 | XP_419685.4 |
Danio rerio (zebrafish) | zgc:172112 | NP_001107119.1 |
Mus musculus (house mouse) | Cnksr3 | NP_766134.1 |
Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates.
Miller JA, Nathanson J, Franjic D, Shim S, Dalley RA, Shapouri S, Smith KA, Sunkin SM, Bernard A, Bennett JL, Lee CK, Hawrylycz MJ, Jones AR, Amaral DG, ?estan N, Gage FH, Lein ES
Development (Cambridge, England)140(22)4633-44(2013 Nov)
Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates assembly of a multiprotein epithelial sodium channel (ENaC)-regulatory complex.
Soundararajan R, Ziera T, Koo E, Ling K, Wang J, Borden SA, Pearce D
The Journal of biological chemistry287(39)33014-25(2012 Sep)
Cnksr3 is a direct mineralocorticoid receptor target gene and plays a key role in the regulation of the epithelial sodium channel.
Ziera T, Irlbacher H, Fromm A, Latouche C, Krug SM, Fromm M, Jaisser F, Borden SA
FASEB journal : official publication of the Federation of American Societies for Experimental Biology23(11)3936-46(2009 Nov)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
CNK3 is a molecular scaffold, which coordinates the assembly of a multiprotein ENaC-regulatory complex and hence plays a central role in Na(+) homeostasis.
Title: Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates assembly of a multiprotein epithelial sodium channel (ENaC)-regulatory complex.
CNKSR3, a homologue of scaffold proteins involved in MAPK pathway regulation, is a direct target of MR and is required for the maintenance of transepithelial sodium transport in the kidney.
Title: Cnksr3 is a direct mineralocorticoid receptor target gene and plays a key role in the regulation of the epithelial sodium channel.
The following Cnksr3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cnksr3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu03660 | |
Clone ID Related Accession (Same CDS sequence) | NM_172546.2 | |
Accession Version | NM_172546.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1668bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-15 | |
Organism | Mus musculus(house mouse) | |
Product | connector enhancer of kinase suppressor of ras 3 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AK033015.1. On Apr 5, 2007 this sequence version replaced NM_172546.1. ##Evidence-Data-START## Transcript exon combination :: AK033015.1, AY151137.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## |
1 | ATGGAGCCCG TGACCAAGTG GAGCCCCAAA CAAGTGGTGG ACTGGACTAG AGGGTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_766134.1 |
CDS | 555..2222 |
Translation |
Target ORF information:
Target ORF information:
|
NM_172546.2 |
1 | ATGGAGCCCG TGACCAAGTG GAGCCCCAAA CAAGTGGTGG ACTGGACTAG AGGGTTGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu72936 | |
Clone ID Related Accession (Same CDS sequence) | XM_011243079.1 | |
Accession Version | XM_011243079.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1737bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | connector enhancer of kinase suppressor of ras 3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTGTGCAT TTTATGTGCA CACCTTGCAG AAGGTACAGA AGGCGGAGGG AGTTCCAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_011241381.1 |
CDS | 631..2367 |
Translation |
Target ORF information:
Target ORF information:
|
XM_011243079.1 |
1 | ATGTGTGCAT TTTATGTGCA CACCTTGCAG AAGGTACAGA AGGCGGAGGG AGTTCCAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu85403 | |
Clone ID Related Accession (Same CDS sequence) | XM_030244998.1 | |
Accession Version | XM_030244998.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1428bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | connector enhancer of kinase suppressor of ras 3 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000076.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAGAACT TGGTTCTGAA ACTGCGGGCA TCTTCCCACA ACTTGCAGAA TTACATCAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_030100858.1 |
CDS | 338..1765 |
Translation |
Target ORF information:
Target ORF information:
|
XM_030244998.1 |
1 | ATGAAGAACT TGGTTCTGAA ACTGCGGGCA TCTTCCCACA ACTTGCAGAA TTACATCAGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. |
Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates assembly of a multiprotein epithelial sodium channel (ENaC)-regulatory complex. |
Cnksr3 is a direct mineralocorticoid receptor target gene and plays a key role in the regulation of the epithelial sodium channel. |