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Pyy cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Pyy
Entrez Gene ID 217212
Full Name peptide YY
General protein information
Preferred Names

peptide YY

Names

peptide YY
Peptide tyrosine tyrosine
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

11

11|11 D

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
NM_145435.1 NP_663410.1 peptide YY isoform 1 precursor
NM_001346771.1 NP_001333700.1 peptide YY isoform 2 precursor

Pathways from BioSystems


Homologies


PYY XP_001113958.1
Bos taurus (cattle) PYY NP_001035677.1
Rattus norvegicus (Norway rat) Pyy NP_001029252.1
Xenopus tropicalis (tropical clawed frog) pyy NP_001072427.1
Homo sapiens (human) PYY NP_004151.3
Pan troglodytes (chimpanzee) PYY XP_523780.3
Danio rerio (zebrafish) pyya NP_001157843.1
Canis lupus familiaris (dog) PYY XP_005624470.1
Mus musculus (house mouse) Pyy NP_663410.1
Danio rerio (zebrafish) pyyb XP_001333222.2

Gene Ontology


Bibliography

Related articles in PubMed

Y5 receptor signalling counteracts the anorectic effects of PYY3-36 in diet-induced obese mice.
Shi YC, Ip CK, Reed F, Sarruf DA, Wulff BS, Herzog H
Journal of neuroendocrinology29(10)(2017 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

expression of PYY and its NPY receptors on mouse islets and immortalised rodent and human beta-cells was examined.
Title: Islet distribution of Peptide YY and its regulatory role in primary mouse islets and immortalised rodent and human beta-cell function and survival.

Angiotensin II stimulates PYY secretion, in turn inhibiting epithelial anion fluxes, thereby reducing net fluid secretion into the colonic lumen.
Title: Angiotensin II Type 1 Receptor-Dependent GLP-1 and PYY Secretion in Mice and Humans.

new information on the cell specific localization of NUCB2/nesfatin-1 in the intestinal mucosa, and a novel function for nesfatin-1 in modulating intestinal CCK and PYY expression and secretion
Title: Nesfatin-1 stimulates cholecystokinin and suppresses peptide YY expression and secretion in mice.

Data (including data from studies in transgenic mice) suggest neurotensin (Nts), glucagon-like peptide I (GLP-1), and peptide YY (Pyy) are closely co-expressed and co-secreted within enteroendocrine cells in ileum mucosa.
Title: Neurotensin Is Coexpressed, Coreleased, and Acts Together With GLP-1 and PYY in Enteroendocrine Control of Metabolism.

pancreatic islet-derived PYY plays an important role in controlling glucose homeostasis through the modulation of beta-cell mass and function
Title: Pancreatic PYY Is Critical in the Control of Insulin Secretion and Glucose Homeostasis in Female Mice.

The following Pyy gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Pyy cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu11560 NM_145435.1
Latest version!		 Mus musculus peptide YY (Pyy), transcript variant 1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 5-7 $69.30
$99.00
OMu46127 NM_001346771.1
Latest version!		 Mus musculus peptide YY (Pyy), transcript variant 2, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone 30% OFF
2-4 Clone 40% OFF
5 or more Clone 50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu11560
Clone ID Related Accession (Same CDS sequence) NM_145435.1
Accession Version NM_145435.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 297bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-24
Organism Mus musculus(house mouse)
Product peptide YY isoform 1 precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC010821.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC010821.1, BB654143.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849389 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
ATGGTGGCGG TGCGCAGGCC TTGGCCCGTC ACGGTCGCAA TGCTGCTAAT CCTGCTCGCC 
TGTCTGGGAG CCCTGGTGGA CGCCTACCCT GCCAAACCAG AGGCTCCCGG CGAAGACGCC 
TCCCCGGAGG AGCTGAGCCG CTACTACGCC TCCCTGCGCC ACTACCTCAA CCTGGTCACC 
CGGCAGCGGT ATGGAAAAAG AGATGTCCCC GCAGCTCTGT TCTCCAAACT GCTCTTCACA 
GACGACAGCG ACAGCGAGAA CCTCCCCTTC AGGCCAGAAG GTTTGGACCA GTGGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_663410.1
CDS37..333
Translation

Target ORF information:

RefSeq Version NM_145435.1
Organism Mus musculus(house mouse)
Definition Mus musculus peptide YY (Pyy), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_145435.1

ORF Insert Sequence:

1
61
121
181
241
ATGGTGGCGG TGCGCAGGCC TTGGCCCGTC ACGGTCGCAA TGCTGCTAAT CCTGCTCGCC 
TGTCTGGGAG CCCTGGTGGA CGCCTACCCT GCCAAACCAG AGGCTCCCGG CGAAGACGCC 
TCCCCGGAGG AGCTGAGCCG CTACTACGCC TCCCTGCGCC ACTACCTCAA CCTGGTCACC 
CGGCAGCGGT ATGGAAAAAG AGATGTCCCC GCAGCTCTGT TCTCCAAACT GCTCTTCACA 
GACGACAGCG ACAGCGAGAA CCTCCCCTTC AGGCCAGAAG GTTTGGACCA GTGGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu46127
Clone ID Related Accession (Same CDS sequence) NM_001346771.1
Accession Version NM_001346771.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 303bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-12-28
Organism Mus musculus(house mouse)
Product peptide YY isoform 2 precursor
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AL591145.25 and BP774079.1. On Oct 30, 2016 this sequence version replaced XM_006533039.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BP762644.1, BY095863.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849389 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
ATGGTGGCGG TGCGCAGGCC TTGGCCCGTC ACGGTCGCAA TGCTGCTAAT CCTGCTCGCC 
TGTCTGGGAG CCCTGGTGGA CGCCTACCCT GCCAAACCAG AGGCTCCCGG CGAAGACGCC 
TCCCCGGAGG AGCTGAGCCG CTACTACGCC TCCCTGCGCC ACTACCTCAA CCTGGTCACC 
CGGCAGCGGT ATGGAAAAAG AGATGTCCCC GCAGCTCTGT TCTCCAAACT GCTCTTCACA 
GACGACAGCG ACAGCGAGAA CCTCCCCTTC AGGTCTCGGC CAGAAGGTTT GGACCAGTGG 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001333700.1
CDS93..395
Translation

Target ORF information:

RefSeq Version NM_001346771.1
Organism Mus musculus(house mouse)
Definition Mus musculus peptide YY (Pyy), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001346771.1

ORF Insert Sequence:

1
61
121
181
241
301
ATGGTGGCGG TGCGCAGGCC TTGGCCCGTC ACGGTCGCAA TGCTGCTAAT CCTGCTCGCC 
TGTCTGGGAG CCCTGGTGGA CGCCTACCCT GCCAAACCAG AGGCTCCCGG CGAAGACGCC 
TCCCCGGAGG AGCTGAGCCG CTACTACGCC TCCCTGCGCC ACTACCTCAA CCTGGTCACC 
CGGCAGCGGT ATGGAAAAAG AGATGTCCCC GCAGCTCTGT TCTCCAAACT GCTCTTCACA 
GACGACAGCG ACAGCGAGAA CCTCCCCTTC AGGTCTCGGC CAGAAGGTTT GGACCAGTGG 
TGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Y5 receptor signalling counteracts the anorectic effects of PYY3-36 in diet-induced obese mice.
Journal of neuroendocrinology29(10)(2017 Oct)
Shi YC,Ip CK,Reed F,Sarruf DA,Wulff BS,Herzog H