Gene Symbol | Cdc42bpb |
Entrez Gene ID | 217866 |
Full Name | CDC42 binding protein kinase beta |
Synonyms | MRCKb |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Cdc42bpb cDNA ORF clone
Gene Symbol | Cdc42bpb |
Entrez Gene ID | 217866 |
Full Name | CDC42 binding protein kinase beta |
Synonyms | MRCKb |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_183016.2 | NP_898837.2 | serine/threonine-protein kinase MRCK beta |
XM_006515763.3 | XP_006515826.1 | serine/threonine-protein kinase MRCK beta isoform X1 |
XM_006515763.2 | XP_006515826.1 | serine/threonine-protein kinase MRCK beta isoform X1 |
Canis lupus familiaris (dog) | CDC42BPB | XP_005623889.1 |
Bos taurus (cattle) | CDC42BPB | XP_003587632.2 |
Danio rerio (zebrafish) | cdc42bpb | NP_001038590.1 |
Xenopus tropicalis (tropical clawed frog) | cdc42bpb | XP_004917233.1 |
Homo sapiens (human) | CDC42BPB | NP_006026.3 |
Pan troglodytes (chimpanzee) | CDC42BPB | XP_510180.2 |
LOC695720 | XP_002805265.1 | |
Mus musculus (house mouse) | Cdc42bpb | NP_898837.2 |
Rattus norvegicus (Norway rat) | Cdc42bpb | NP_446072.2 |
Gallus gallus (chicken) | CDC42BPB | XP_004936409.1 |
Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in lamellipodial F-actin dynamics.
Lee IC, Leung T, Tan I
The Journal of biological chemistry289(39)26989-7003(2014 Sep)
The mouse kinome: discovery and comparative genomics of all mouse protein kinases.
Caenepeel S, Charydczak G, Sudarsanam S, Hunter T, Manning G
Proceedings of the National Academy of Sciences of the United States of America101(32)11707-12(2004 Aug)
Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif.
Tomsig JL, Snyder SL, Creutz CE
The Journal of biological chemistry278(12)10048-54(2003 Mar)
The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain.
Kalantry S, Manning S, Haub O, Tomihara-Newberger C, Lee HG, Fangman J, Disteche CM, Manova K, Lacy E
Nature genetics27(4)412-6(2001 Apr)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
First identified and named MRCKb based on sequence similarity to MRCKa (CDC42bpa) and orthology to human MRCKb/CDC42bpb
Title: The mouse kinome: discovery and comparative genomics of all mouse protein kinases.
The following Cdc42bpb gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cdc42bpb cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu47775 | |
Clone ID Related Accession (Same CDS sequence) | XM_006515763.3 , XM_006515763.2 | |
Accession Version | XM_006515763.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5193bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | serine/threonine-protein kinase MRCK beta isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006515763.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCGGCCA AGGTGCGGCT CAAGAAGCTG GAGCAGCTGC TCCTGGACGG GCCGTGGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006515826.1 |
CDS | 2043..7235 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006515763.3 |
1 | ATGTCGGCCA AGGTGCGGCT CAAGAAGCTG GAGCAGCTGC TCCTGGACGG GCCGTGGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu08283 | |
Clone ID Related Accession (Same CDS sequence) | NM_183016.2 | |
Accession Version | NM_183016.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5142bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | serine/threonine-protein kinase MRCK beta | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC127580.3. On Jan 6, 2010 this sequence version replaced NM_183016.1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: AY277589.1, BC138035.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN00849374, SAMN00849375 [ECO:0000350] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCGGCCA AGGTGCGGCT CAAGAAGCTG GAGCAGCTGC TCCTGGACGG GCCGTGGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_898837.2 |
CDS | 448..5589 |
Translation |
Target ORF information:
Target ORF information:
|
NM_183016.2 |
1 | ATGTCGGCCA AGGTGCGGCT CAAGAAGCTG GAGCAGCTGC TCCTGGACGG GCCGTGGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu47775 | |
Clone ID Related Accession (Same CDS sequence) | XM_006515763.3 , XM_006515763.2 | |
Accession Version | XM_006515763.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 5193bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | serine/threonine-protein kinase MRCK beta isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000078.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006515763.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCGGCCA AGGTGCGGCT CAAGAAGCTG GAGCAGCTGC TCCTGGACGG GCCGTGGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006515826.1 |
CDS | 448..5640 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006515763.2 |
1 | ATGTCGGCCA AGGTGCGGCT CAAGAAGCTG GAGCAGCTGC TCCTGGACGG GCCGTGGCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Adaptor protein LRAP25 mediates myotonic dystrophy kinase-related Cdc42-binding kinase (MRCK) regulation of LIMK1 protein in lamellipodial F-actin dynamics. |
The mouse kinome: discovery and comparative genomics of all mouse protein kinases. |
Identification of targets for calcium signaling through the copine family of proteins. Characterization of a coiled-coil copine-binding motif. |
The amnionless gene, essential for mouse gastrulation, encodes a visceral-endoderm-specific protein with an extracellular cysteine-rich domain. |