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Tppp2 cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Tppp2
Entrez Gene ID 219038
Full Name tubulin polymerization-promoting protein family member 2
Synonyms Gm1790,Gm77
General protein information
Preferred Names

tubulin polymerization-promoting protein family member 2

Names

tubulin polymerization-promoting protein family member 2
p25 beta
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

14

14|14 C1

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_006518844.3 XP_006518907.1 tubulin polymerization-promoting protein family member 2 isoform X1
NM_001128634.1 NP_001122106.1 tubulin polymerization-promoting protein family member 2
XM_006518844.4 XP_006518907.1 tubulin polymerization-promoting protein family member 2 isoform X1

Pathways from BioSystems


Homologies


Pan troglodytes (chimpanzee) TPPP2 XP_528697.2
Rattus norvegicus (Norway rat) Tppp2 NP_001102570.1
Caenorhabditis elegans (roundworm) C32E8.3 NP_491219.1
Homo sapiens (human) TPPP2 NP_776245.2
Canis lupus familiaris (dog) TPPP2 XP_532620.2
Mus musculus (house mouse) Tppp2 NP_001122106.1
Bos taurus (cattle) TPPP2 NP_001029456.1
Gallus gallus (chicken) TPPP2 XP_424853.1
TPPP2 XP_001093843.1

Gene Ontology


Bibliography

Related articles in PubMed

Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells.
Yalcin S, Zhang X, Luciano JP, Mungamuri SK, Marinkovic D, Vercherat C, Sarkar A, Grisotto M, Taneja R, Ghaffari S
The Journal of biological chemistry283(37)25692-705(2008 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Foxo3 represses ROS in part via regulation of ATM and this repression is required for maintenance of the hematopoietic stem cell pool
Title: Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells.

The following Tppp2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Tppp2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu06031 NM_001128634.1
Latest version!		 Mus musculus tubulin polymerization-promoting protein family member 2 (Tppp2), mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
OMu06031 XM_006518844.4
Latest version!		 Mus musculus tubulin polymerization-promoting protein family member 2 (Tppp2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 9-11 $69.30
$99.00
View Old Accession Versions >>
OMu06031 XM_006518844.3 Mus musculus tubulin polymerization-promoting protein family member 2 (Tppp2), transcript variant X1, mRNA. pcDNA3.1+/C-(K)DYK or customized vector 7-9 $69.30
$99.00
Hide Old Accession Versions >>

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu06031
Clone ID Related Accession (Same CDS sequence) XM_006518844.3 , NM_001128634.1 , XM_006518844.4
Accession Version NM_001128634.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-11-11
Organism Mus musculus(house mouse)
Product tubulin polymerization-promoting protein family member 2
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from BC049709.1. On or before Jun 22, 2008 this sequence version replaced XM_907853.3, XM_359331.5, XM_001479332.1. ##Evidence-Data-START## Transcript exon combination :: BU936364.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849384 [ECO:0000348] ##Evidence-Data-END## 

1
61
121
181
241
301
361
421
481
ATGGCCTCAG AAGCAGAAAG AACATTCCAT CGATTCGCTG TCTTTGGAGA ATCATCCAGC 
AGCAGCAAGG AAATTACCAA CAAGAACTTC TCCAAACTCT GTAAAGACTG TGATATCATG 
GATGGCAAGG CAGTGACCTC CACAGATGTG GACATTGTGT TCAGCAAAGT GAAGGCCAAG 
AATGCCAGAA CCATCAACTT TCAACAGTTT CAAGAGGCAA TGAAGGAGCT GGGCCAAAAG 
CGCTTCAAGG GGAAGAACCC AGATGAGGCT TTGCAAGGTG TTTTTAAACT CATGGAAGGC 
AAAGATCCTG CCACCACCGG TGTCACTAAA TCAACGACGG TGGGTGGAGT AGACCGGTTG 
ACAGACACCA GTAAGTACAC CGGAACTCAC AAGGAGCGCT TTGATGAGAG TGGTAAGGGA 
AAAGGTATTG AAGGTCGGGA AGAGACCACT GACAACTCAG GCTACGTGAG TGGCTACAAG 
GGGGCCGGCA CCTATGACAA GAAAAACCAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001122106.1
CDS28..540
Translation

Target ORF information:

RefSeq Version NM_001128634.1
Organism Mus musculus(house mouse)
Definition Mus musculus tubulin polymerization-promoting protein family member 2 (Tppp2), mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001128634.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGCCTCAG AAGCAGAAAG AACATTCCAT CGATTCGCTG TCTTTGGAGA ATCATCCAGC 
AGCAGCAAGG AAATTACCAA CAAGAACTTC TCCAAACTCT GTAAAGACTG TGATATCATG 
GATGGCAAGG CAGTGACCTC CACAGATGTG GACATTGTGT TCAGCAAAGT GAAGGCCAAG 
AATGCCAGAA CCATCAACTT TCAACAGTTT CAAGAGGCAA TGAAGGAGCT GGGCCAAAAG 
CGCTTCAAGG GGAAGAACCC AGATGAGGCT TTGCAAGGTG TTTTTAAACT CATGGAAGGC 
AAAGATCCTG CCACCACCGG TGTCACTAAA TCAACGACGG TGGGTGGAGT AGACCGGTTG 
ACAGACACCA GTAAGTACAC CGGAACTCAC AAGGAGCGCT TTGATGAGAG TGGTAAGGGA 
AAAGGTATTG AAGGTCGGGA AGAGACCACT GACAACTCAG GCTACGTGAG TGGCTACAAG 
GGGGCCGGCA CCTATGACAA GAAAAACCAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu06031
Clone ID Related Accession (Same CDS sequence) XM_006518844.3 , NM_001128634.1 , XM_006518844.4
Accession Version XM_006518844.3 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product tubulin polymerization-promoting protein family member 2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006518844.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
ATGGCCTCAG AAGCAGAAAG AACATTCCAT CGATTCGCTG TCTTTGGAGA ATCATCCAGC 
AGCAGCAAGG AAATTACCAA CAAGAACTTC TCCAAACTCT GTAAAGACTG TGATATCATG 
GATGGCAAGG CAGTGACCTC CACAGATGTG GACATTGTGT TCAGCAAAGT GAAGGCCAAG 
AATGCCAGAA CCATCAACTT TCAACAGTTT CAAGAGGCAA TGAAGGAGCT GGGCCAAAAG 
CGCTTCAAGG GGAAGAACCC AGATGAGGCT TTGCAAGGTG TTTTTAAACT CATGGAAGGC 
AAAGATCCTG CCACCACCGG TGTCACTAAA TCAACGACGG TGGGTGGAGT AGACCGGTTG 
ACAGACACCA GTAAGTACAC CGGAACTCAC AAGGAGCGCT TTGATGAGAG TGGTAAGGGA 
AAAGGTATTG AAGGTCGGGA AGAGACCACT GACAACTCAG GCTACGTGAG TGGCTACAAG 
GGGGCCGGCA CCTATGACAA GAAAAACCAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006518907.1
CDS141..653
Translation

Target ORF information:

RefSeq Version XM_006518844.3
Organism Mus musculus(house mouse)
Definition Mus musculus tubulin polymerization-promoting protein family member 2 (Tppp2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006518844.3

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGCCTCAG AAGCAGAAAG AACATTCCAT CGATTCGCTG TCTTTGGAGA ATCATCCAGC 
AGCAGCAAGG AAATTACCAA CAAGAACTTC TCCAAACTCT GTAAAGACTG TGATATCATG 
GATGGCAAGG CAGTGACCTC CACAGATGTG GACATTGTGT TCAGCAAAGT GAAGGCCAAG 
AATGCCAGAA CCATCAACTT TCAACAGTTT CAAGAGGCAA TGAAGGAGCT GGGCCAAAAG 
CGCTTCAAGG GGAAGAACCC AGATGAGGCT TTGCAAGGTG TTTTTAAACT CATGGAAGGC 
AAAGATCCTG CCACCACCGG TGTCACTAAA TCAACGACGG TGGGTGGAGT AGACCGGTTG 
ACAGACACCA GTAAGTACAC CGGAACTCAC AAGGAGCGCT TTGATGAGAG TGGTAAGGGA 
AAAGGTATTG AAGGTCGGGA AGAGACCACT GACAACTCAG GCTACGTGAG TGGCTACAAG 
GGGGCCGGCA CCTATGACAA GAAAAACCAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu06031
Clone ID Related Accession (Same CDS sequence) XM_006518844.3 , NM_001128634.1 , XM_006518844.4
Accession Version XM_006518844.4 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 513bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Mus musculus(house mouse)
Product tubulin polymerization-promoting protein family member 2 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000080.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006518844.3. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
361
421
481
ATGGCCTCAG AAGCAGAAAG AACATTCCAT CGATTCGCTG TCTTTGGAGA ATCATCCAGC 
AGCAGCAAGG AAATTACCAA CAAGAACTTC TCCAAACTCT GTAAAGACTG TGATATCATG 
GATGGCAAGG CAGTGACCTC CACAGATGTG GACATTGTGT TCAGCAAAGT GAAGGCCAAG 
AATGCCAGAA CCATCAACTT TCAACAGTTT CAAGAGGCAA TGAAGGAGCT GGGCCAAAAG 
CGCTTCAAGG GGAAGAACCC AGATGAGGCT TTGCAAGGTG TTTTTAAACT CATGGAAGGC 
AAAGATCCTG CCACCACCGG TGTCACTAAA TCAACGACGG TGGGTGGAGT AGACCGGTTG 
ACAGACACCA GTAAGTACAC CGGAACTCAC AAGGAGCGCT TTGATGAGAG TGGTAAGGGA 
AAAGGTATTG AAGGTCGGGA AGAGACCACT GACAACTCAG GCTACGTGAG TGGCTACAAG 
GGGGCCGGCA CCTATGACAA GAAAAACCAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_006518907.1
CDS137..649
Translation

Target ORF information:

RefSeq Version XM_006518844.4
Organism Mus musculus(house mouse)
Definition Mus musculus tubulin polymerization-promoting protein family member 2 (Tppp2), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_006518844.4

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
ATGGCCTCAG AAGCAGAAAG AACATTCCAT CGATTCGCTG TCTTTGGAGA ATCATCCAGC 
AGCAGCAAGG AAATTACCAA CAAGAACTTC TCCAAACTCT GTAAAGACTG TGATATCATG 
GATGGCAAGG CAGTGACCTC CACAGATGTG GACATTGTGT TCAGCAAAGT GAAGGCCAAG 
AATGCCAGAA CCATCAACTT TCAACAGTTT CAAGAGGCAA TGAAGGAGCT GGGCCAAAAG 
CGCTTCAAGG GGAAGAACCC AGATGAGGCT TTGCAAGGTG TTTTTAAACT CATGGAAGGC 
AAAGATCCTG CCACCACCGG TGTCACTAAA TCAACGACGG TGGGTGGAGT AGACCGGTTG 
ACAGACACCA GTAAGTACAC CGGAACTCAC AAGGAGCGCT TTGATGAGAG TGGTAAGGGA 
AAAGGTATTG AAGGTCGGGA AGAGACCACT GACAACTCAG GCTACGTGAG TGGCTACAAG 
GGGGCCGGCA CCTATGACAA GAAAAACCAG TAG

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

Foxo3 is essential for the regulation of ataxia telangiectasia mutated and oxidative stress-mediated homeostasis of hematopoietic stem cells.
The Journal of biological chemistry283(37)25692-705(2008 Sep)
Yalcin S,Zhang X,Luciano JP,Mungamuri SK,Marinkovic D,Vercherat C,Sarkar A,Grisotto M,Taneja R,Ghaffari S