Gene Symbol | Hdac11 |
Entrez Gene ID | 232232 |
Full Name | histone deacetylase 11 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Hdac11 cDNA ORF clone
gRNAs
Gene Symbol | Hdac11 |
Entrez Gene ID | 232232 |
Full Name | histone deacetylase 11 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006505995.2 | XP_006506058.1 | histone deacetylase 11 isoform X1 |
NM_144919.2 | NP_659168.1 | histone deacetylase 11 |
XM_017321536.1 | XP_017177025.1 | histone deacetylase 11 isoform X3 |
XM_006505995.1 | XP_006506058.1 | histone deacetylase 11 isoform X1 |
XM_017321535.1 | XP_017177024.1 | histone deacetylase 11 isoform X2 |
HDAC11 | XP_001082767.1 | |
Danio rerio (zebrafish) | hdac11 | NP_001002171.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP001736 | XP_321350.5 |
Arabidopsis thaliana (thale cress) | HDA2 | NP_568480.2 |
Oryza sativa (rice) | Os06g0571100 | NP_001057914.1 |
Bos taurus (cattle) | HDAC11 | NP_001095526.1 |
Gallus gallus (chicken) | HDAC11 | NP_001264070.1 |
Mus musculus (house mouse) | Hdac11 | NP_659168.1 |
Drosophila melanogaster (fruit fly) | HdacX | NP_001247296.1 |
Caenorhabditis elegans (roundworm) | hda-11 | NP_505699.3 |
Homo sapiens (human) | HDAC11 | NP_079103.2 |
Pan troglodytes (chimpanzee) | HDAC11 | XP_530587.3 |
Canis lupus familiaris (dog) | HDAC11 | XP_005632164.1 |
Rattus norvegicus (Norway rat) | Hdac11 | NP_001100080.2 |
HDAC11 Inhibits Myoblast Differentiation through Repression of MyoD-Dependent Transcription.
Byun SK, An TH, Son MJ, Lee DS, Kang HS, Lee EW, Han BS, Kim WK, Bae KH, Oh KJ, Lee SC
Molecules and cells40(9)667-676(2017 Sep)
Disruption to schizophrenia-associated gene Fez1 in the hippocampus of HDAC11 knockout mice.
Bryant DT, Landles C, Papadopoulou AS, Benjamin AC, Duckworth JK, Rosahl T, Benn CL, Bates GP
Scientific reports7(1)11900(2017 Sep)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
our results indicate that the alcohol-induced responsiveness of Kupffer cells to gut-derived endotoxin, in part, is governed by miR-155 and HDAC11
Title: Alcohol-induced miR-155 and HDAC11 inhibit negative regulators of the TLR4 pathway and lead to increased LPS responsiveness of Kupffer cells in alcoholic liver disease.
we have been able to demonstrate a lineage-restricted overexpression of HDAC11 in neutrophils and committed neutrophil precursors and it appears to associate with the transcription machinery, possibly regulating the expression of inflammatory and migratory genes in neutrophils. Our results highlight a unique and novel role for HDAC11
Title: Essential role for histone deacetylase 11 (HDAC11) in neutrophil biology.
HDAC11-knockout T cells displayed enhanced proliferation, proinflammatory cytokine production, and effector molecule expression of Eomes and TBX21 transcription factors previously shown to regulate inflammatory cytokine and effector molecule production.
Title: T cells lacking HDAC11 have increased effector functions and mediate enhanced alloreactivity in a murine model.
HDAC11 appears to function as a negative regulator of myeloid-derived suppressor cells expansion/function in vivo.
Title: Histone deacetylase 11: A novel epigenetic regulator of myeloid derived suppressor cell expansion and function.
HDAC6, primarily a cytoplasmic protein, associates with HDAC11 and modulates the expression of IL-10 as a transcriptional activator.
Title: Divergent roles of histone deacetylase 6 (HDAC6) and histone deacetylase 11 (HDAC11) on the transcriptional regulation of IL10 in antigen presenting cells.
The following Hdac11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Hdac11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu11253 | |
Clone ID Related Accession (Same CDS sequence) | NM_144919.2 | |
Accession Version | NM_144919.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1044bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-27 | |
Organism | Mus musculus(house mouse) | |
Product | histone deacetylase 11 | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AC110256.12 and AC131764.3. On Nov 17, 2006 this sequence version replaced NM_144919.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: BC016208.1, AK045994.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCTCACG CAACACAGCT GTACCAGCAT GTACCAGAGA AACGCTGGCC CATCGTGTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_659168.1 |
CDS | 32..1075 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGCCTCACG CAACACAGCT GTACCAGCAT GTACCAGAGA AACGCTGGCC CATCGTGTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu37182 | |
Clone ID Related Accession (Same CDS sequence) | XM_006505995.2 , XM_006505995.1 | |
Accession Version | XM_006505995.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | histone deacetylase 11 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTGGGAG TTCTCTTCCA CCCAGAGAGC CTGTGCCGTC CCTCAGGTGG TGGCTTCCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006506058.1 |
CDS | 95..772 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTTGGGAG TTCTCTTCCA CCCAGAGAGC CTGTGCCGTC CCTCAGGTGG TGGCTTCCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu37182 | |
Clone ID Related Accession (Same CDS sequence) | XM_006505995.2 , XM_006505995.1 | |
Accession Version | XM_006505995.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 678bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | histone deacetylase 11 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006505995.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTGGGAG TTCTCTTCCA CCCAGAGAGC CTGTGCCGTC CCTCAGGTGG TGGCTTCCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006506058.1 |
CDS | 405..1082 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGTTGGGAG TTCTCTTCCA CCCAGAGAGC CTGTGCCGTC CCTCAGGTGG TGGCTTCCAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu81700 | |
Clone ID Related Accession (Same CDS sequence) | XM_017321535.1 | |
Accession Version | XM_017321535.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 657bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | histone deacetylase 11 isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGGCGT GTGTTCTGCG TAGGCCCTGC CTCTTGCACC CCTCCCACCC CTCCCGGTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017177024.1 |
CDS | 81..737 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGAGGCGT GTGTTCTGCG TAGGCCCTGC CTCTTGCACC CCTCCCACCC CTCCCGGTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu81701 | |
Clone ID Related Accession (Same CDS sequence) | XM_017321536.1 | |
Accession Version | XM_017321536.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | histone deacetylase 11 isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000072.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGAGGCGT GTGTTCTGCG TAGGCCCTGC CTCTTGCACC CCTCCCACCC CTCCCGGTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_017177025.1 |
CDS | 81..656 |
Translation |
Target ORF information:
Target ORF information:
|
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1 | ATGGAGGCGT GTGTTCTGCG TAGGCCCTGC CTCTTGCACC CCTCCCACCC CTCCCGGTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
HDAC11 Inhibits Myoblast Differentiation through Repression of MyoD-Dependent Transcription. |
Disruption to schizophrenia-associated gene Fez1 in the hippocampus of HDAC11 knockout mice. |