Gene Symbol | Rnf40 |
Entrez Gene ID | 233900 |
Full Name | ring finger protein 40 |
Synonyms | AI848422,mKIAA0661 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Rnf40 cDNA ORF clone
Gene Symbol | Rnf40 |
Entrez Gene ID | 233900 |
Full Name | ring finger protein 40 |
Synonyms | AI848422,mKIAA0661 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
XM_006507749.2 | XP_006507812.1 | E3 ubiquitin-protein ligase BRE1B isoform X1 |
XM_006507750.2 | XP_006507813.1 | E3 ubiquitin-protein ligase BRE1B isoform X2 |
XM_006507751.3 | XP_006507814.1 | E3 ubiquitin-protein ligase BRE1B isoform X3 |
XM_006507750.3 | XP_006507813.1 | E3 ubiquitin-protein ligase BRE1B isoform X2 |
NM_001360883.1 | NP_001347812.1 | E3 ubiquitin-protein ligase BRE1B isoform 2 |
XM_006507749.3 | XP_006507812.1 | E3 ubiquitin-protein ligase BRE1B isoform X1 |
NM_172281.2 | NP_758485.2 | E3 ubiquitin-protein ligase BRE1B isoform 1 |
Mus musculus (house mouse) | Rnf40 | NP_758485.2 |
Homo sapiens (human) | RNF40 | NP_055586.1 |
RNF40 | XP_001102375.2 | |
Pan troglodytes (chimpanzee) | RNF40 | XP_003315121.1 |
Rattus norvegicus (Norway rat) | Rnf40 | NP_703201.1 |
Xenopus tropicalis (tropical clawed frog) | rnf40 | XP_004918162.1 |
Drosophila melanogaster (fruit fly) | Bre1 | NP_647989.2 |
Canis lupus familiaris (dog) | RNF40 | XP_005621328.1 |
Bos taurus (cattle) | RNF40 | NP_001193381.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP007335 | XP_308493.4 |
Caenorhabditis elegans (roundworm) | rfp-1 | NP_001022700.1 |
Transcriptome analysis for UVB-induced phototoxicity in mouse retina.
An MJ, Kim CH, Nam GY, Kim DH, Rhee S, Cho SJ, Kim JW
Environmental toxicology33(1)52-62(2018 Jan)
RNF40 regulates gene expression in an epigenetic context-dependent manner.
Xie W, Nagarajan S, Baumgart SJ, Kosinsky RL, Najafova Z, Kari V, Hennion M, Indenbirken D, Bonn S, Grundhoff A, Wegwitz F, Mansouri A, Johnsen SA
Genome biology18(1)32(2017 Feb)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Our results support a model in which the direct function of RNF40-mediated H2B monoubiquitination increases transcriptional elongation by promoting the spreading of H3K4me3 into the 5' transcribed region of a select subgroup of genes.
Title: RNF40 regulates gene expression in an epigenetic context-dependent manner.
We show that Bre1 (human BRE1A/B (RNF20/40) and mouse Bre1a/b (Rnf20/40)) acts as an important suppressor of chromosomal instability
Title: Deficiency in mammalian histone H2B ubiquitin ligase Bre1 (Rnf20/Rnf40) leads to replication stress and chromosomal instability.
the observed defects in the radiation response of Bre1a/b-deficient cells
Title: Deficiency in Bre1 impairs homologous recombination repair and cell cycle checkpoint response to radiation damage in mammalian cells.
The following Rnf40 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Rnf40 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu39580 | |
Clone ID Related Accession (Same CDS sequence) | XM_006507751.3 , NM_001360883.1 | |
Accession Version | NM_001360883.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2007bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-31 | |
Organism | Mus musculus(house mouse) | |
Product | E3 ubiquitin-protein ligase BRE1B isoform 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC122417.4 and BM899169.1. On Feb 16, 2018 this sequence version replaced XM_006507751.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660815.239982.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTTGAATG CAGAGCTGGA AGAAAATCAG GAATTGGCCA ATAGCCGAAT GGCAGAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001347812.1 |
CDS | 1089..3095 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001360883.1 |
1 | ATGTTGAATG CAGAGCTGGA AGAAAATCAG GAATTGGCCA ATAGCCGAAT GGCAGAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu39580 | |
Clone ID Related Accession (Same CDS sequence) | XM_006507751.3 , NM_001360883.1 | |
Accession Version | XM_006507751.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2007bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | E3 ubiquitin-protein ligase BRE1B isoform X3 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006507751.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTTGAATG CAGAGCTGGA AGAAAATCAG GAATTGGCCA ATAGCCGAAT GGCAGAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006507814.1 |
CDS | 1065..3071 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006507751.3 |
1 | ATGTTGAATG CAGAGCTGGA AGAAAATCAG GAATTGGCCA ATAGCCGAAT GGCAGAGCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu39578 | |
Clone ID Related Accession (Same CDS sequence) | XM_006507749.2 , XM_006507749.3 | |
Accession Version | XM_006507749.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3039bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | E3 ubiquitin-protein ligase BRE1B isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006507749.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCTGGCC TCAGCAACAA GCGCGCCGCC GGCGACGGGG GCTCAGGACC CCCAGAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006507812.1 |
CDS | 185..3223 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006507749.3 |
1 | ATGTCTGGCC TCAGCAACAA GCGCGCCGCC GGCGACGGGG GCTCAGGACC CCCAGAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu39579 | |
Clone ID Related Accession (Same CDS sequence) | XM_006507750.2 , XM_006507750.3 | |
Accession Version | XM_006507750.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3021bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-07 | |
Organism | Mus musculus(house mouse) | |
Product | E3 ubiquitin-protein ligase BRE1B isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_006507750.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCTGGCC TCAGCAACAA GCGCGCCGCC GGCGACGGGG GCTCAGGACC CCCAGAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006507813.1 |
CDS | 185..3205 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006507750.3 |
1 | ATGTCTGGCC TCAGCAACAA GCGCGCCGCC GGCGACGGGG GCTCAGGACC CCCAGAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu15259 | |
Clone ID Related Accession (Same CDS sequence) | NM_172281.2 | |
Accession Version | NM_172281.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3006bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-31 | |
Organism | Mus musculus(house mouse) | |
Product | E3 ubiquitin-protein ligase BRE1B isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC122417.4, AK171462.1 and BM899169.1. On May 1, 2009 this sequence version replaced NM_172281.1. ##Evidence-Data-START## Transcript exon combination :: AK154982.1, SRR1660817.189860.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849374, SAMN00849375 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGTCTGGCC TCAGCAACAA GCGCGCCGCC GGCGACGGGG GCTCAGGACC CCCAGAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_758485.2 |
CDS | 187..3192 |
Translation |
Target ORF information:
Target ORF information:
|
NM_172281.2 |
1 | ATGTCTGGCC TCAGCAACAA GCGCGCCGCC GGCGACGGGG GCTCAGGACC CCCAGAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu39578 | |
Clone ID Related Accession (Same CDS sequence) | XM_006507749.2 , XM_006507749.3 | |
Accession Version | XM_006507749.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3039bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | E3 ubiquitin-protein ligase BRE1B isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006507749.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCTGGCC TCAGCAACAA GCGCGCCGCC GGCGACGGGG GCTCAGGACC CCCAGAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006507812.1 |
CDS | 182..3220 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006507749.2 |
1 | ATGTCTGGCC TCAGCAACAA GCGCGCCGCC GGCGACGGGG GCTCAGGACC CCCAGAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OMu39579 | |
Clone ID Related Accession (Same CDS sequence) | XM_006507750.2 , XM_006507750.3 | |
Accession Version | XM_006507750.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3021bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-21 | |
Organism | Mus musculus(house mouse) | |
Product | E3 ubiquitin-protein ligase BRE1B isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_006507750.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGTCTGGCC TCAGCAACAA GCGCGCCGCC GGCGACGGGG GCTCAGGACC CCCAGAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_006507813.1 |
CDS | 182..3202 |
Translation |
Target ORF information:
Target ORF information:
|
XM_006507750.2 |
1 | ATGTCTGGCC TCAGCAACAA GCGCGCCGCC GGCGACGGGG GCTCAGGACC CCCAGAGAAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Transcriptome analysis for UVB-induced phototoxicity in mouse retina. |
RNF40 regulates gene expression in an epigenetic context-dependent manner. |