Gene Symbol | Mbd3l2 |
Entrez Gene ID | 234988 |
Full Name | methyl-CpG binding domain protein 3-like 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
ORF » Species Summary » Mus musculus » Mbd3l2 cDNA ORF clone
gRNAs
Gene Symbol | Mbd3l2 |
Entrez Gene ID | 234988 |
Full Name | methyl-CpG binding domain protein 3-like 2 |
General protein information |
|
Gene Type | protein-coding |
Organism | Mus musculus(house mouse) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_144934.3 | NP_659183.3 | methyl-CpG binding domain protein 3-like 2 |
Homo sapiens (human) | MBD3L4 | NP_001157891.1 |
Homo sapiens (human) | MBD3L3 | NP_001157897.1 |
Pan troglodytes (chimpanzee) | MBD3L2 | XP_001165954.1 |
Rattus norvegicus (Norway rat) | LOC100363016 | XP_002729925.1 |
Rattus norvegicus (Norway rat) | LOC100912114 | XP_003752238.1 |
Pan troglodytes (chimpanzee) | MBD3L2 | XP_001144438.1 |
Pan troglodytes (chimpanzee) | MBD3L2 | XP_524079.2 |
LOC705273 | XP_001093645.1 | |
LOC705142 | XP_001093522.1 | |
Bos taurus (cattle) | MBD3L3 | XP_002688877.2 |
Mus musculus (house mouse) | Mbd3l2 | NP_659183.3 |
Rattus norvegicus (Norway rat) | Mbd3l2 | XP_235852.3 |
Canis lupus familiaris (dog) | LOC100688619 | XP_003432915.2 |
Homo sapiens (human) | LOC729458 | XP_001130308.1 |
Pan troglodytes (chimpanzee) | LOC749125 | XP_001165749.2 |
Pan troglodytes (chimpanzee) | MBD3L2 | XP_001165919.1 |
Pan troglodytes (chimpanzee) | MBD3L2 | XP_001165993.1 |
Homo sapiens (human) | MBD3L5 | NP_001129979.1 |
Homo sapiens (human) | MBD3L2 | NP_653215.2 |
Haploid male germ cell- and oocyte-specific Mbd3l1 and Mbd3l2 genes are dispensable for early development, fertility, and zygotic DNA demethylation in the mouse.
Jin SG, Tsark W, Szab? PE, Pfeifer GP
Developmental dynamics : an official publication of the American Association of Anatomists237(11)3435-43(2008 Nov)
MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing.
Jin SG, Jiang CL, Rauch T, Li H, Pfeifer GP
The Journal of biological chemistry280(13)12700-9(2005 Apr)
MBD3L1 and MBD3L2, two new proteins homologous to the methyl-CpG-binding proteins MBD2 and MBD3: characterization of MBD3L1 as a testis-specific transcriptional repressor.
Jiang CL, Jin SG, Lee DH, Lan ZJ, Xu X, O'Connor TR, Szab? PE, Mann JR, Cooney AJ, Pfeifer GP
Genomics80(6)621-9(2002 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Mbd3l1 and Mbd3l2 are not involved in genome-wide demethylation of paternal genomes in mouse zygotes and are dispensable for normal development.
Title: Haploid male germ cell- and oocyte-specific Mbd3l1 and Mbd3l2 genes are dispensable for early development, fertility, and zygotic DNA demethylation in the mouse.
MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing
Title: MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing.
The following Mbd3l2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Mbd3l2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OMu25321 | |
Clone ID Related Accession (Same CDS sequence) | NM_144934.3 | |
Accession Version | NM_144934.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 687bp) Protein sequence SNP |
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Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-27 | |
Organism | Mus musculus(house mouse) | |
Product | methyl-CpG binding domain protein 3-like 2 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC162941.5, AK135772.1 and BC064744.1. On Aug 6, 2009 this sequence version replaced NM_144934.2. ##Evidence-Data-START## Transcript exon combination :: BC064744.1, AK135772.1 [ECO:0000332] ##Evidence-Data-END## |
1 | ATGGAGGAGA CTTCAAGAAA CTCAGTTTCA AGCCAGCCTT TGATAGGAAG TCTCACAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_659183.3 |
CDS | 220..906 |
Translation |
Target ORF information:
Target ORF information:
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1 | ATGGAGGAGA CTTCAAGAAA CTCAGTTTCA AGCCAGCCTT TGATAGGAAG TCTCACAAGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Haploid male germ cell- and oocyte-specific Mbd3l1 and Mbd3l2 genes are dispensable for early development, fertility, and zygotic DNA demethylation in the mouse. |
MBD3L2 interacts with MBD3 and components of the NuRD complex and can oppose MBD2-MeCP1-mediated methylation silencing. |
MBD3L1 and MBD3L2, two new proteins homologous to the methyl-CpG-binding proteins MBD2 and MBD3: characterization of MBD3L1 as a testis-specific transcriptional repressor. |