Cd52 cDNA ORF clone, Mus musculus(house mouse)
| Gene Symbol | Cd52 |
| Entrez Gene ID | 23833 |
| Full Name | CD52 antigen |
| Synonyms | AI463198,B7,B7-Ag,CAMPATH-1,CLS1,MB7 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Mus musculus(house mouse) |
| Genome |
mRNA and Protein(s)
| mRNA | Protein | Name |
|---|---|---|
| NM_013706.2 | NP_038734.1 | CAMPATH-1 antigen precursor |
Related articles in PubMed
CD52 inhibits Toll-like receptor activation of NF-?B and triggers apoptosis to suppress inflammation.
Rashidi M, Bandala-Sanchez E, Lawlor KE, Zhang Y, Neale AM, Vijayaraj SL, O'Donoghue R, Wentworth JM, Adams TE, Vince JE, Harrison LC
Cell death and differentiation25(2)392-405(2018 Feb)
Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent.
Chen JQ, Mori H, Cardiff RD, Trott JF, Hovey RC, Hubbard NE, Engelberg JA, Tepper CG, Willis BJ, Khan IH, Ravindran RK, Chan SR, Schreiber RD, Borowsky AD
PloS one10(6)e0129895(2015)
T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10.
Bandala-Sanchez E, Zhang Y, Reinwald S, Dromey JA, Lee BH, Qian J, B?hmer RM, Harrison LC
Nature immunology14(7)741-8(2013 Jul)
Impact of lactobacilli on orally acquired listeriosis.
Archambaud C, Nahori MA, Soubigou G, B?cavin C, Laval L, Lechat P, Smokvina T, Langella P, Lecuit M, Cossart P
Proceedings of the National Academy of Sciences of the United States of America109(41)16684-9(2012 Oct)
DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice.
Abdallah BM, Ditzel N, Mahmood A, Isa A, Traustadottir GA, Schilling AF, Ruiz-Hidalgo MJ, Laborda J, Amling M, Kassem M
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research26(7)1457-71(2011 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Soluble CD52 is used by certain CD4-positive cells to suppress target celss via the inhibitory receptor Siglec-10.
Title: T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10.
expression is induced in the mouse uterus at the time of embryo implantation
Title: CD52 expression is induced in the mouse uterus at the time of embryo implantation.
Study helps to precisely define CD52 expression in the tumor cell population of PTCL and might therefore be valuable when evaluating the response to alemtuzumab therapy in prospective clinical trials.
Title: CD52 expression in peripheral T-cell lymphomas determined by combined immunophenotyping using tumor cell specific T-cell receptor antibodies.
The results indicate CD52 is not required for fertilization in the mouse either in vivo or in vitro.
Title: Cd52, known as a major maturation-associated sperm membrane antigen secreted from the epididymis, is not required for fertilization in the mouse.
study examined the tissue distribution, molecular composition and immunogenicity of mouse male reproductive tract-CD52
Title: Biochemical property and immunogenicity of mouse male reproductive tract CD52 (mrt-CD52).
The following Cd52 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cd52 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OMu09817 | |
| Clone ID Related Accession (Same CDS sequence) | NM_013706.2 | |
| Accession Version | NM_013706.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 225bp) Protein sequence SNP |
|
| Vector | pcDNA3.1+/C-(K)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-19 | |
| Organism | Mus musculus(house mouse) | |
| Product | CAMPATH-1 antigen precursor | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK155728.1 and BC027495.1. On Oct 31, 2007 this sequence version replaced NM_013706.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: AI021439.1, AK155728.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849381, SAMN00849383 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. | |
1 | ATGAAGAGCT TCCTCCTCTT CCTCACTATC ATTCTTCTGG TTGTGATTCA GATACAAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_038734.1 |
| CDS | 90..314 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_013706.2 |
ORF Insert Sequence:
1 | ATGAAGAGCT TCCTCCTCTT CCTCACTATC ATTCTTCTGG TTGTGATTCA GATACAAACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
 |
CD52 inhibits Toll-like receptor activation of NF-?B and triggers apoptosis to suppress inflammation. |
|
Abnormal Mammary Development in 129:STAT1-Null Mice is Stroma-Dependent. |
|
T cell regulation mediated by interaction of soluble CD52 with the inhibitory receptor Siglec-10. |
|
Impact of lactobacilli on orally acquired listeriosis. |
|
DLK1 is a novel regulator of bone mass that mediates estrogen deficiency-induced bone loss in mice. |