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Cib1 cDNA ORF clone, Mus musculus(house mouse)

Summary

Gene Symbol Cib1
Entrez Gene ID 23991
Full Name calcium and integrin binding 1 (calmyrin)
Synonyms Cibkip,Kip,Prkdcip
General protein information
Preferred Names

calcium and integrin binding 1 (calmyrin)

Names

calcium and integrin-binding protein 1
CIB
DNA-PKcs-interacting protein
calcium and integrin binding, protein kinase interacting protein
calmyrin
kinase-interacting protein
protein kinase, DNA activated, catalytic polypeptide interacting protein
Gene Type protein-coding
Organism Mus musculus(house mouse)
Genome

7

7|7 D2

Reference Sequences (RefSeq)

mRNA and Protein(s)

mRNA Protein Name
XM_011250861.2 XP_011249163.1 calcium and integrin-binding protein 1 isoform X1
XM_030242553.1 XP_030098413.1 calcium and integrin-binding protein 1 isoform X1
XM_011250861.3 XP_011249163.1 calcium and integrin-binding protein 1 isoform X1
NM_001291276.1 NP_001278205.1 calcium and integrin-binding protein 1 isoform 3
NM_001291275.1 NP_001278204.1 calcium and integrin-binding protein 1 isoform 2
NM_011870.5 NP_036000.1 calcium and integrin-binding protein 1 isoform 1

Pathways from BioSystems


Homologies


CIB1 XP_001096008.1
Mus musculus (house mouse) Cib1 NP_036000.1
Gallus gallus (chicken) CIB1 NP_001264577.1
Danio rerio (zebrafish) cib1 NP_001017681.1
Homo sapiens (human) CIB1 NP_006375.2
Canis lupus familiaris (dog) CIB1 XP_849876.1
Pan troglodytes (chimpanzee) CIB1 XP_510591.2
Rattus norvegicus (Norway rat) Cib1 NP_112407.1
Bos taurus (cattle) CIB1 NP_001068901.1
Danio rerio (zebrafish) LOC100536377 XP_003201427.1
Anopheles gambiae (African malaria mosquito) AgaP_AGAP008474 XP_316971.2
Xenopus tropicalis (tropical clawed frog) cib1 NP_001011480.1

Gene Ontology


Bibliography

Related articles in PubMed

CIB1 protects against MPTP-induced neurotoxicity through inhibiting ASK1.
Yoon KW, Yang HS, Kim YM, Kim Y, Kang S, Sun W, Naik UP, Parise LV, Choi EJ
Scientific reports7(1)12178(2017 Sep)

CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.
Giese APJ, Tang YQ, Sinha GP, Bowl MR, Goldring AC, Parker A, Freeman MJ, Brown SDM, Riazuddin S, Fettiplace R, Schafer WR, Frolenkov GI, Ahmed ZM
Nature communications8(1)43(2017 06)

Binding of CIB1 to the ?IIb tail of ?IIb?3 is required for FAK recruitment and activation in platelets.
Naik MU, Naik TU, Summer R, Naik UP
PloS one12(5)e0176602(2017)

Biophysical and structural studies of the human calcium- and integrin-binding protein family: understanding their functional similarities and differences.
Huang H, Bogstie JN, Vogel HJ
Biochemistry and cell biology = Biochimie et biologie cellulaire90(5)646-56(2012 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

results suggest that interaction of CIB1 with alphaIIb is one of the early events occurring during outside-in signaling. Furthermore, CIB1 recruits FAK to the alphaIIbbeta3 complex at the filopodia where FAK is activated, which in turn activates c-Src, resulting in propagation of outside-in signaling leading to platelet spreading.
Title: Binding of CIB1 to the ?IIb tail of ?IIb?3 is required for FAK recruitment and activation in platelets.

CIB1 is involved in regulating endomitosis, perhaps through its interaction with Polo-like kinase 3
Title: Calcium- and integrin-binding protein 1 regulates endomitosis and its interaction with Polo-like kinase 3 is enhanced in endomitotic Dami cells.

CIB1 functions as a previously undescribed regulator of cardiac hypertrophy through its ability to regulate the association of calcineurin with the sarcolemma and its activation.
Title: CIB1 is a regulator of pathological cardiac hypertrophy.

Data demonstrate that CIB1 is not required for AID to mediate antibody gene diversification processes. It remains possible that CIB1 has an alternative, a redundant or a subtle non-limiting regulatory role in AID biology.
Title: The interaction between AID and CIB1 is nonessential for antibody gene diversification by gene conversion or class switch recombination.

CIB1 is a key regulator of thrombosis, by affecting platelet spreading, but not platelet filopodia formation.
Title: CIB1 deficiency results in impaired thrombosis: the potential role of CIB1 in outside-in signaling through integrin alpha IIb beta 3.

The following Cib1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the Cib1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID Accession No. Definition **Vector *Turnaround time Price (USD) Select
OMu16476 NM_001291275.1
Latest version!		 Mus musculus calcium and integrin binding 1 (calmyrin) (Cib1), transcript variant 2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
OMu16479 NM_001291276.1
Latest version!		 Mus musculus calcium and integrin binding 1 (calmyrin) (Cib1), transcript variant 3, mRNA. pcDNA3.1-C-(k)DYK or customized vector 7-9 $69.30
$99.00
OMu16478 NM_011870.5
Latest version!		 Mus musculus calcium and integrin binding 1 (calmyrin) (Cib1), transcript variant 1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $69.30
$99.00
OMu69159 XM_011250861.3
Latest version!		 Mus musculus calcium and integrin binding 1 (calmyrin) (Cib1), transcript variant X2, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $69.30
$99.00
OMu69159 XM_030242553.1
Latest version!		 Mus musculus calcium and integrin binding 1 (calmyrin) (Cib1), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 9-11 $69.30
$99.00
View Old Accession Versions >>
OMu69159 XM_011250861.2 Mus musculus calcium and integrin binding 1 (calmyrin) (Cib1), transcript variant X1, mRNA. pcDNA3.1-C-(k)DYK or customized vector 5-7 $69.30
$99.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)


CloneID OMu69159
Clone ID Related Accession (Same CDS sequence) XM_011250861.2 , XM_030242553.1 , XM_011250861.3
Accession Version XM_011250861.2 Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 354bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2016-06-21
Organism Mus musculus(house mouse)
Product calcium and integrin-binding protein 1 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Jun 22, 2016 this sequence version replaced XM_011250861.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Mus musculus Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.1 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
ATGGTCTTCT CCACATCACC TACCAGAGAC AGCCTGAGCT TTGAGGACTT CCTGGACCTC 
CTGAGTGTCT TCAGTGACAC AGCAACCCCA GACATCAAGT CACACTATGC CTTCCGCATC 
TTTGACTTTG ATGACGATGG AACCCTGGAC AGAGAAGACC TGAGCCAGCT TGTGAATTGC 
CTCACGGGAG AGGGCGAGGA CACTCGGCTC AGTGCTTCTG AGATGAAGCA GCTGATTGAC 
AATATCCTGG AAGAGTCAGA CATTGACAGG GATGGGACCA TCAATCTTTC CGAGTTCCAG 
CATGTCATCT CGCGCTCACC AGACTTTGCC AGCTCCTTTA AGATTGTCCT GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011249163.1
CDS391..744
Translation

Target ORF information:

RefSeq Version XM_011250861.2
Organism Mus musculus(house mouse)
Definition Mus musculus calcium and integrin binding 1 (calmyrin) (Cib1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011250861.2

ORF Insert Sequence:

1
61
121
181
241
301
ATGGTCTTCT CCACATCACC TACCAGAGAC AGCCTGAGCT TTGAGGACTT CCTGGACCTC 
CTGAGTGTCT TCAGTGACAC AGCAACCCCA GACATCAAGT CACACTATGC CTTCCGCATC 
TTTGACTTTG ATGACGATGG AACCCTGGAC AGAGAAGACC TGAGCCAGCT TGTGAATTGC 
CTCACGGGAG AGGGCGAGGA CACTCGGCTC AGTGCTTCTG AGATGAAGCA GCTGATTGAC 
AATATCCTGG AAGAGTCAGA CATTGACAGG GATGGGACCA TCAATCTTTC CGAGTTCCAG 
CATGTCATCT CGCGCTCACC AGACTTTGCC AGCTCCTTTA AGATTGTCCT GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu16476
Clone ID Related Accession (Same CDS sequence) NM_001291275.1
Accession Version NM_001291275.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 561bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-11-15
Organism Mus musculus(house mouse)
Product calcium and integrin-binding protein 1 isoform 2
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CF104297.1, AK152805.1 and BP770454.1. Transcript Variant: This variant (2) uses an alternate in-frame splice junction at the 5' end of an exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CK031089.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849386, SAMN00849389 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
ATGGGAGGTT CGGGCAGTCG CCTGTCTAAG GAGCTGCTGG CCGAGTACCA GGACCTGACG 
TTCCTGACCA AGCAGGAGAT CCTCCTAGCC CACAGACGCT TTTGTGAGCT GCTTCCCCCA 
GAGCAGCGGA CCGTGGAGGA GTCACTGCAC ACCCGAGTAT CGTTTGAGCA GATCCTCAGC 
CTCCCAGAGC TCAAGGAGCG AATCTGCATG GTCTTCTCCA CATCACCTAC CAGAGACAGC 
CTGAGCTTTG AGGACTTCCT GGACCTCCTG AGTGTCTTCA GTGACACAGC AACCCCAGAC 
ATCAAGTCAC ACTATGCCTT CCGCATCTTT GACTTTGATG ACGATGGAAC CCTGGACAGA 
GAAGACCTGA GCCAGCTTGT GAATTGCCTC ACGGGAGAGG GCGAGGACAC TCGGCTCAGT 
GCTTCTGAGA TGAAGCAGCT GATTGACAAT ATCCTGGAAG AGTCAGACAT TGACAGGGAT 
GGGACCATCA ATCTTTCCGA GTTCCAGCAT GTCATCTCGC GCTCACCAGA CTTTGCCAGC 
TCCTTTAAGA TTGTCCTGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278204.1
CDS246..806
Translation

Target ORF information:

RefSeq Version NM_001291275.1
Organism Mus musculus(house mouse)
Definition Mus musculus calcium and integrin binding 1 (calmyrin) (Cib1), transcript variant 2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001291275.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGGAGGTT CGGGCAGTCG CCTGTCTAAG GAGCTGCTGG CCGAGTACCA GGACCTGACG 
TTCCTGACCA AGCAGGAGAT CCTCCTAGCC CACAGACGCT TTTGTGAGCT GCTTCCCCCA 
GAGCAGCGGA CCGTGGAGGA GTCACTGCAC ACCCGAGTAT CGTTTGAGCA GATCCTCAGC 
CTCCCAGAGC TCAAGGAGCG AATCTGCATG GTCTTCTCCA CATCACCTAC CAGAGACAGC 
CTGAGCTTTG AGGACTTCCT GGACCTCCTG AGTGTCTTCA GTGACACAGC AACCCCAGAC 
ATCAAGTCAC ACTATGCCTT CCGCATCTTT GACTTTGATG ACGATGGAAC CCTGGACAGA 
GAAGACCTGA GCCAGCTTGT GAATTGCCTC ACGGGAGAGG GCGAGGACAC TCGGCTCAGT 
GCTTCTGAGA TGAAGCAGCT GATTGACAAT ATCCTGGAAG AGTCAGACAT TGACAGGGAT 
GGGACCATCA ATCTTTCCGA GTTCCAGCAT GTCATCTCGC GCTCACCAGA CTTTGCCAGC 
TCCTTTAAGA TTGTCCTGTG A

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu16479
Clone ID Related Accession (Same CDS sequence) NM_001291276.1
Accession Version NM_001291276.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 432bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-11-15
Organism Mus musculus(house mouse)
Product calcium and integrin-binding protein 1 isoform 3
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CF104297.1, BB843350.1, AK152805.1 and BP770454.1. On Apr 1, 2014 this sequence version replaced XM_006540859.1. Transcript Variant: This variant (3) lacks an alternate in-frame segment compared to variant 1. The resulting isoform (3) has the same N- and C-termini but is shorter compared to isoform 1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: CK021021.1, AK088450.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849377, SAMN00849380 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
ATGGGAGGTT CGGGCAGTCG CCTGTCTAAG GAGCTGCTGG CCGAGTACCA GGCTAACCCT 
TTCAAGGAGC GAATCTGCAT GGTCTTCTCC ACATCACCTA CCAGAGACAG CCTGAGCTTT 
GAGGACTTCC TGGACCTCCT GAGTGTCTTC AGTGACACAG CAACCCCAGA CATCAAGTCA 
CACTATGCCT TCCGCATCTT TGACTTTGAT GACGATGGAA CCCTGGACAG AGAAGACCTG 
AGCCAGCTTG TGAATTGCCT CACGGGAGAG GGCGAGGACA CTCGGCTCAG TGCTTCTGAG 
ATGAAGCAGC TGATTGACAA TATCCTGGAA GAGTCAGACA TTGACAGGGA TGGGACCATC 
AATCTTTCCG AGTTCCAGCA TGTCATCTCG CGCTCACCAG ACTTTGCCAG CTCCTTTAAG 
ATTGTCCTGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_001278205.1
CDS246..677
Translation

Target ORF information:

RefSeq Version NM_001291276.1
Organism Mus musculus(house mouse)
Definition Mus musculus calcium and integrin binding 1 (calmyrin) (Cib1), transcript variant 3, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_001291276.1

ORF Insert Sequence:

1
61
121
181
241
301
361
421
ATGGGAGGTT CGGGCAGTCG CCTGTCTAAG GAGCTGCTGG CCGAGTACCA GGCTAACCCT 
TTCAAGGAGC GAATCTGCAT GGTCTTCTCC ACATCACCTA CCAGAGACAG CCTGAGCTTT 
GAGGACTTCC TGGACCTCCT GAGTGTCTTC AGTGACACAG CAACCCCAGA CATCAAGTCA 
CACTATGCCT TCCGCATCTT TGACTTTGAT GACGATGGAA CCCTGGACAG AGAAGACCTG 
AGCCAGCTTG TGAATTGCCT CACGGGAGAG GGCGAGGACA CTCGGCTCAG TGCTTCTGAG 
ATGAAGCAGC TGATTGACAA TATCCTGGAA GAGTCAGACA TTGACAGGGA TGGGACCATC 
AATCTTTCCG AGTTCCAGCA TGTCATCTCG CGCTCACCAG ACTTTGCCAG CTCCTTTAAG 
ATTGTCCTGT GA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu16478
Clone ID Related Accession (Same CDS sequence) NM_011870.5
Accession Version NM_011870.5 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 576bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-11-15
Organism Mus musculus(house mouse)
Product calcium and integrin-binding protein 1 isoform 1
Comment Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from CF104297.1, AK152805.1 and BP770454.1. On Apr 1, 2014 this sequence version replaced NM_011870.4. Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1). Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: DV055722.1, CK020088.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN00849386, SAMN00849389 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. 

1
61
121
181
241
301
361
421
481
541
ATGGGAGGTT CGGGCAGTCG CCTGTCTAAG GAGCTGCTGG CCGAGTACCA GGACCTGACG 
TTCCTGACCA AGCAGGAGAT CCTCCTAGCC CACAGACGCT TTTGTGAGCT GCTTCCCCCA 
GAGCAGCGGA CCGTGGAGGA GTCACTGCAC ACCCGAGTAT CGTTTGAGCA GATCCTCAGC 
CTCCCAGAGC TCAAGGCTAA CCCTTTCAAG GAGCGAATCT GCATGGTCTT CTCCACATCA 
CCTACCAGAG ACAGCCTGAG CTTTGAGGAC TTCCTGGACC TCCTGAGTGT CTTCAGTGAC 
ACAGCAACCC CAGACATCAA GTCACACTAT GCCTTCCGCA TCTTTGACTT TGATGACGAT 
GGAACCCTGG ACAGAGAAGA CCTGAGCCAG CTTGTGAATT GCCTCACGGG AGAGGGCGAG 
GACACTCGGC TCAGTGCTTC TGAGATGAAG CAGCTGATTG ACAATATCCT GGAAGAGTCA 
GACATTGACA GGGATGGGAC CATCAATCTT TCCGAGTTCC AGCATGTCAT CTCGCGCTCA 
CCAGACTTTG CCAGCTCCTT TAAGATTGTC CTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq NP_036000.1
CDS246..821
Translation

Target ORF information:

RefSeq Version NM_011870.5
Organism Mus musculus(house mouse)
Definition Mus musculus calcium and integrin binding 1 (calmyrin) (Cib1), transcript variant 1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 NM_011870.5

ORF Insert Sequence:

1
61
121
181
241
301
361
421
481
541
ATGGGAGGTT CGGGCAGTCG CCTGTCTAAG GAGCTGCTGG CCGAGTACCA GGACCTGACG 
TTCCTGACCA AGCAGGAGAT CCTCCTAGCC CACAGACGCT TTTGTGAGCT GCTTCCCCCA 
GAGCAGCGGA CCGTGGAGGA GTCACTGCAC ACCCGAGTAT CGTTTGAGCA GATCCTCAGC 
CTCCCAGAGC TCAAGGCTAA CCCTTTCAAG GAGCGAATCT GCATGGTCTT CTCCACATCA 
CCTACCAGAG ACAGCCTGAG CTTTGAGGAC TTCCTGGACC TCCTGAGTGT CTTCAGTGAC 
ACAGCAACCC CAGACATCAA GTCACACTAT GCCTTCCGCA TCTTTGACTT TGATGACGAT 
GGAACCCTGG ACAGAGAAGA CCTGAGCCAG CTTGTGAATT GCCTCACGGG AGAGGGCGAG 
GACACTCGGC TCAGTGCTTC TGAGATGAAG CAGCTGATTG ACAATATCCT GGAAGAGTCA 
GACATTGACA GGGATGGGAC CATCAATCTT TCCGAGTTCC AGCATGTCAT CTCGCGCTCA 
CCAGACTTTG CCAGCTCCTT TAAGATTGTC CTGTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu69159
Clone ID Related Accession (Same CDS sequence) XM_011250861.2 , XM_030242553.1 , XM_011250861.3
Accession Version XM_030242553.1 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 354bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Mus musculus(house mouse)
Product calcium and integrin-binding protein 1 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
ATGGTCTTCT CCACATCACC TACCAGAGAC AGCCTGAGCT TTGAGGACTT CCTGGACCTC 
CTGAGTGTCT TCAGTGACAC AGCAACCCCA GACATCAAGT CACACTATGC CTTCCGCATC 
TTTGACTTTG ATGACGATGG AACCCTGGAC AGAGAAGACC TGAGCCAGCT TGTGAATTGC 
CTCACGGGAG AGGGCGAGGA CACTCGGCTC AGTGCTTCTG AGATGAAGCA GCTGATTGAC 
AATATCCTGG AAGAGTCAGA CATTGACAGG GATGGGACCA TCAATCTTTC CGAGTTCCAG 
CATGTCATCT CGCGCTCACC AGACTTTGCC AGCTCCTTTA AGATTGTCCT GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_030098413.1
CDS778..1131
Translation

Target ORF information:

RefSeq Version XM_030242553.1
Organism Mus musculus(house mouse)
Definition Mus musculus calcium and integrin binding 1 (calmyrin) (Cib1), transcript variant X1, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_030242553.1

ORF Insert Sequence:

1
61
121
181
241
301
ATGGTCTTCT CCACATCACC TACCAGAGAC AGCCTGAGCT TTGAGGACTT CCTGGACCTC 
CTGAGTGTCT TCAGTGACAC AGCAACCCCA GACATCAAGT CACACTATGC CTTCCGCATC 
TTTGACTTTG ATGACGATGG AACCCTGGAC AGAGAAGACC TGAGCCAGCT TGTGAATTGC 
CTCACGGGAG AGGGCGAGGA CACTCGGCTC AGTGCTTCTG AGATGAAGCA GCTGATTGAC 
AATATCCTGG AAGAGTCAGA CATTGACAGG GATGGGACCA TCAATCTTTC CGAGTTCCAG 
CATGTCATCT CGCGCTCACC AGACTTTGCC AGCTCCTTTA AGATTGTCCT GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

CloneID OMu69159
Clone ID Related Accession (Same CDS sequence) XM_011250861.2 , XM_030242553.1 , XM_011250861.3
Accession Version XM_011250861.3 Latest version! Documents for ORF clone product in default vector
Sequence Information ORF Nucleotide Sequence (Length: 354bp)
Protein sequence
SNP
Vector pcDNA3.1+/C-(K)DYK or customized vector User Manual
Clone information Clone Map MSDS
Tag on pcDNA3.1+/C-(K)DYK C terminal DYKDDDDK tags
ORF Insert Method CloneEZ™ Seamless cloning technology
Insert Structure linear
Update Date 2019-08-07
Organism Mus musculus(house mouse)
Product calcium and integrin-binding protein 1 isoform X1
Comment Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000073.6) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Aug 8, 2019 this sequence version replaced XM_011250861.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Mus musculus Annotation Release 108 Annotation Version :: 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.2 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## 

1
61
121
181
241
301
ATGGTCTTCT CCACATCACC TACCAGAGAC AGCCTGAGCT TTGAGGACTT CCTGGACCTC 
CTGAGTGTCT TCAGTGACAC AGCAACCCCA GACATCAAGT CACACTATGC CTTCCGCATC 
TTTGACTTTG ATGACGATGG AACCCTGGAC AGAGAAGACC TGAGCCAGCT TGTGAATTGC 
CTCACGGGAG AGGGCGAGGA CACTCGGCTC AGTGCTTCTG AGATGAAGCA GCTGATTGAC 
AATATCCTGG AAGAGTCAGA CATTGACAGG GATGGGACCA TCAATCTTTC CGAGTTCCAG 
CATGTCATCT CGCGCTCACC AGACTTTGCC AGCTCCTTTA AGATTGTCCT GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

RefSeq XP_011249163.1
CDS407..760
Translation

Target ORF information:

RefSeq Version XM_011250861.3
Organism Mus musculus(house mouse)
Definition Mus musculus calcium and integrin binding 1 (calmyrin) (Cib1), transcript variant X2, mRNA.

Target ORF information:

Epitope DYKDDDDK
Bacterial selection AMPR
Mammalian selection NeoR
Vector pcDNA3.1+/C-(K)DYK
 XM_011250861.3

ORF Insert Sequence:

1
61
121
181
241
301
ATGGTCTTCT CCACATCACC TACCAGAGAC AGCCTGAGCT TTGAGGACTT CCTGGACCTC 
CTGAGTGTCT TCAGTGACAC AGCAACCCCA GACATCAAGT CACACTATGC CTTCCGCATC 
TTTGACTTTG ATGACGATGG AACCCTGGAC AGAGAAGACC TGAGCCAGCT TGTGAATTGC 
CTCACGGGAG AGGGCGAGGA CACTCGGCTC AGTGCTTCTG AGATGAAGCA GCTGATTGAC 
AATATCCTGG AAGAGTCAGA CATTGACAGG GATGGGACCA TCAATCTTTC CGAGTTCCAG 
CATGTCATCT CGCGCTCACC AGACTTTGCC AGCTCCTTTA AGATTGTCCT GTGA

The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.

PubMed

book

CIB1 protects against MPTP-induced neurotoxicity through inhibiting ASK1.
Scientific reports7(1)12178(2017 Sep)
Yoon KW,Yang HS,Kim YM,Kim Y,Kang S,Sun W,Naik UP,Parise LV,Choi EJ


book

CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells.
Nature communications8(1)43(2017 06)
Giese APJ,Tang YQ,Sinha GP,Bowl MR,Goldring AC,Parker A,Freeman MJ,Brown SDM,Riazuddin S,Fettiplace R,Schafer WR,Frolenkov GI,Ahmed ZM


book

Binding of CIB1 to the ?IIb tail of ?IIb?3 is required for FAK recruitment and activation in platelets.
PloS one12(5)e0176602(2017)
Naik MU,Naik TU,Summer R,Naik UP


book

Biophysical and structural studies of the human calcium- and integrin-binding protein family: understanding their functional similarities and differences.
Biochemistry and cell biology = Biochimie et biologie cellulaire90(5)646-56(2012 Oct)
Huang H,Bogstie JN,Vogel HJ